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Reconstruction of Rabbit Corneal Layer Composed of Corneal Fibroblasts and Corneal Epithelium on the Lyophilized Amniotic Membrane

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Chemical Research in Chinese Universities 2006年第2期22卷 150-156页

作者： AHN Jae-il JANG In-keun YOON Mun-young SEO Young-kwon YOON Hee-hun KIN Jae-chan SONG Kye-yong YANG Eun-kyung park jung-keug Department of Chemical and Biochemical Engineering Dongguk University Seoul Korea Department of Ophthalmology Chung-Ang University Hospital Seoul Korea Department of Pathology College of Medicine Chung-Ang University Seoul Korea R & D Center Bioland Ltd. Chun-An Korea

Many researchers have employed the cryopreserved amniotic membrane（CAM） and corneal epithelial cells in the treatment of a severely damaged burned cornea, with corneal epithelial cells cultured on an amniotic membrane （AM）. The lyophilized amniotic membrane（LAM） has a higher graft take and a longer shelf life; it is easier to store and safer because of gamma irradiation. Two Teflon rings（ Ahn＇s supporter） were made for culturing the cells on the LAM, and were then used to support the LAM. To reconstruct a corneal layer composed of corneal fibroblasts and epithelium, the corneal fibroblasts were first cultivated on the stromal side of LAM for five days, foUowed by epithelial cells culture on the epithelial side, by using the air-liquid interface culture. The reconstructed corneal layer composed of corneal fibroblasts and corneal epithelial cells has a much healthier basal layer of corneal epithelium than the reconstructed corneal epithelium, which was got by using only corneal epithelial cells, and resembles the epithelium of normal corneas, without the horny layer. Thus, the reconstruction of the corneal layer by using a LAM is considered to be a good in vitro model, not only for its application in toxicological test kits, but also for transplantation in patients with a severely damaged cornea.

关键词： Lyophilized amniotic membrane Corneal layer Corneal fibroblast Corneal epithelium

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Prominent cycling reversibility and kinetics enabled by CaTiO3 protective layer on Zn metal for aqueous Zn-ion batteries

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Journal of Energy Chemistry 2025年第1期100卷 245-258页

作者： Gaeun Lee Yong Nam Ahn Seongjoon So Chanwoo park Jong-Seong Bae Taehyun park Il Tae Kim Jaehyun Hur School of Chemical Biological and Battery Engineering Gachon University Seongnam Busan Center Korea Basic Science Institute

Aqueous Zn-ion batteries （AZIBs） have received considerable attention owing to their various advantages such as safety,low cost,simple battery assembly conditions,and high ionic ***,they still suffer from serious problems,including uncontrollable dendrite growth,corrosion,hydrogen evolution reaction （HER） from water decomposition,electrode passivation,and unexpected *** creation of a uniform artificial nanocrystal layer on the Zn anode surface is a promising strategy for resolving these ***,we propose the use of a perovskite CaTiO3（CTO） protective layer on Zn（CTO@Zn） as a promising approach for improving the performance of *** CTO artificial layer provides an efficient pathway for Zn ion diffusion towards the Zn metal because of the high dielectric constant （εr=180） and ferroelectric characteristics that enable the alignment of dipole moments and redistribute the Zn2+ions in the CTO *** avoiding the direct contact of the Zn anode with the electrolyte solution,the uneven dendrite growth,corrosion,parasitic side reactions,and HER are mitigated,while CTO retains its mechanical and chemical robustness during ***,CTO@Zn demonstrates an improved lifespan in a symmetric cell configuration compared with bare ***@Zn shows steady overpotential （～68 m V） for 1500 h at 1 mA cm-2/0.5 mA h cm-2,excelling bare ***,when paired with the V2O5-C cathode,the CTO@Zn//V2O5-C full battery delivers 148.4 mA h g-1（based on the mass of the cathode） after 300 *** study provides new insights into Zn metal anodes and the development of high-performance AZIBs.

关键词： Artificial layer Dielectric constant Zn metal anode Zinc aqueous battery

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Development of Bioartificial Skin using Tissue Engineering

Development of Bioartificial Skin using Tissue Engineering

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中国生物工程学会第三次全国会员代表大会暨学术讨论会

作者： jung keug park Tissue Eng. Lab Dept. Chem. Eng. Dongguk Univ. Seoul Korea

Objective Bioartificial skin for grafting is required high-strength scaffold to overcome the problem of easily being tom during handling. But gel-type bioartificial skin has low mechanical strength and furthermore appropriate crosslinking methods cannot be accepted in it. We made bioartificial skin for grafting using collagen scaffold in the form of sponge that was prepared by freeze-drying of 5.0 mg/ml of type I collagen solution. And then we examined various cross-linking effects when chemical cross-linkings were perfomed with glutaraldehyde, hexamethylene diisocyanate, and ascorbic acid, and also physical cross-linkings were performed

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Silica-quaternary ammonium “Fixed-Quat” nanofilm coated fiberglass mesh for water disinfection and harmful algal blooms control

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Journal of Environmental Sciences 2019年第8期31卷 213-224页

作者： Daniela Diaz Jared Church Mikaeel Young keug Tae Kim jungsu park Yun Bin Hwang Swadeshmukul Santra Woo Hyoung Lee Department of Civil Environmental and Construction Engineering University of Central Florida NanoScience Technology Center University of Central Florida Burnett School of Biomedical Sciences University of Central Florida Department of Environmental & Energy Engineering Suwon University K-water Institute Korea Water Resources Corporation Department of Material Science and Engineering 4000 Central Florida Blvd University of Central Florida Department of Chemistry 4111 Libra Drive University of Central Florida

Intensification of pollution loading worldwide has promoted an escalation of different types of disease-causing microorganisms, such as harmful algal blooms(HABs), instigating detrimental impacts on the quality of receiving surface waters. Formation of unwanted disinfection by-products(DBPs) resulting from conventional disinfection technologies reveals the need for the development of new sustainable alternatives. Quaternary Ammonium Compounds(QACs) are cationic surfactants widely known for their effective biocidal properties at the ppm level. In this study, a novel silica-based antimicrobial nanofilm was developed using a composite of silica-modified QAC(Fixed-Quat) and applied to a fiberglass mesh as an active surface via sol–gel technique. The synthesized Fixed-Quat nanocoating was found to be effective against E. coli with an inactivation rate of 1.3 × 10^(-3) log reduction/cm min. The Fixed-Quat coated fiberglass mesh also demonstrated successful control of Microcystis aeruginosa with more than 99% inactivation after 10 hr of *** developed antimicrobial mesh was also evaluated with wild-type microalgal species collected in a water body experiencing HABs, obtaining a 97% removal efficiency. Overall,the silica-functionalized Fixed-Quat nanocoating showed promising antimicrobial properties for water disinfection and HABs control, while decreasing concerns related to DBPs formation and the possible release of toxic nanomaterials into the environment.

关键词： Fiberglass mesh HAB mitigation Nanocoating Quaternary ammonium compounds(QACs) Silica-functionalization Water disinfection

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A method for automatically translating print books into electronic Braille books

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Science China(Information Sciences) 2016年第7期59卷 129-142页

作者： Taekeun park jungil jung Jinsoo CHO Department of Applied Computer Engineering Dankook University Department of IT Convergence Engineering Gachon University Department of Computer Engineering Gachon University

In this paper, a method for automatically translating scanned images from print books into electronic Braille books is proposed with the objective of reducing the amount of time and cost required for producing Braille books. The proposed method consists of processes for identifying character and image areas in a scanned image, automatically translating characters and images into Braille and tactile graphics, respectively, and positioning Braille and tactile graphics into an electronic Braille page. Experimental results show that the proposed method drastically reduces the time required to translate a print book into an electronic Braille book. Despite the drastic reduction in translation time, the method proposed in this paper does not compromise the ability to recognize information for the visually impaired compared to manually produced Braille books, demonstrating its feasibility in practical applications. Therefore, the proposed method is expected to significantly reduce the time and cost required for producing Braille books, and provide more reading materials for the visually impaired,making significant contributions to enhancing their knowledge and welfare.

关键词： Braille tactile graphic electronic Braille book automatic translation the visually impaired

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Reduced interface energy loss in non-fullerene organic solar cells using room temperature-synthesized SnO2 quantum dots

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Journal of Materials Science & Technology 2020年第17期52卷 12-19页

作者： In Su Jin Minwoo park Jae Woong jung Department of Advanced Materials Engineering for Information&Electronics Kyung Hee University1732 Deogyeong-daeroGiheung-guYongin-siGyeonggi-do 446-701Republic of Korea Department of Chemical and Biological Engineering Sookmyung Women's UniversitySeoul 04310Republic of Korea

We herein report the room temperature synthesis of colloidal SnO2 quantum dots and their application in non-fullerene organic solar cells as an excellent electron transport *** thiourea-assisted hydrolysis at room temperature affords the nanocrystalline SnO2 quantum dots with a diameter of 3-4 *** utilization of the SnO2 quantum dots as an electron transporting layer effectively reduces the interfacial trap density and charge recombination in the solar cell devices,leading to not only the reduced energy loss but also excellent photocurrent *** optimized organic solar cells employing SnO2 quantum dots with polyethylenimine ethoxylated achieves power conversion efficiencies up to 12.023%with a VOC,a JSC,and a FF of 0.89 V,18.89 mA cm^–2,and *** work suggest that the SnO2 quantum dot is a promising electron transporting material to construct efficient organic solar cells for practical *** work also demonstrates the key strategy for thiourea-assisted hydrolysis to synthesize fine and nanocrystalline SnO2 quantum dots.

关键词： Energy loss Organic solar cells Interface SnO2 Quantum dots

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Effect of monovalent charge compensators on the photoluminescence properties of Ca_(3)(PO_(4))_(2):Tb^(3+),A^(+)(A=Li,Na,K)phosphors

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Journal of Materials Science & Technology 2021年第23期82卷 187-196页

作者： G.W.jung K.park Faculty of Nanotechnology and Advanced Materials Engineering Sejong UniversitySeoul05006Republic of Korea

Ca_(3-x)(PO_(4))_(2):xTb^(3+)(0.2≤x≤0.4),Ca_(2.3)(PO_(4))_(2):0.35 Tb^(3+),0.35 A^(+)(A=Li,Na,K),and Ca_(2.3)(PO_(4))_(2):0.35 Tb^(3+),yLi^(+)(0.35≤y≤0.455)phosphors were prepared by solid-state *** the prepared phosphors formed a rhombohedral unit cell with the R3c space *** improve the photoluminescence(PL)properties of the Ca_(2.65)(PO_(4))_(2):0.35 Tb^(3+)phosphor,monovalent charge compensators such as Li^(+),NA^(+),and K^(+)were added to the Ca_(2.65)(PO_(4))_(2):0.35 Tb^(3+)*** charge compensators acted as fluxes,so they improved the *** excitation and emission properties were significantly improved through the incorporation of charge *** particular,among the charge compensators,Li^(+)ion substantially enhanced the emission intensity and color ***,considering the evaporation of Li_(2)CO_(3)during the annealing process,we optimized the concentration of Li^(+)charge compensator to enhance its PL ***,the green emission intensity of the Ca_(2.3)(PO_(4))_(2):0.35 Tb^(3+),0.385 Li^(+)phosphor was 260%higher than that of the Ca_(2.65)(PO_(4))_(2):0.35 Tb^(3+)*** believe that the effect of charge compensators on the PL properties and the optimum concentration of Li^(+)cha rge compensator are useful for the design of phosphors in light-emitting diodes.

关键词： Optical properties Ca_(3)(PO_(4))_(2) Emission Excitation Charge compensator

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Mobilization of monocytic myeloid-derived suppressor cells is regulated by PTH1R activation in bone marrow stromal cells

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Bone Research 2023年第2期11卷 354-367页

作者： Eun jung Lee Kyoung Jin Lee Seungpil jung Kyong Hwa park Serk In park Department of Biochemistry and Molecular Biology Korea University College of MedicineSeoulRepublic of Korea The BK21 Graduate Program Department of Biomedical SciencesKorea University College of MedicineSeoulRepublic of Korea Division of Breast and Endocrine Surgery Department of SurgeryKorea University Anam HospitalSeoulRepublic of Korea Division of Oncology and Hematology Department of Internal MedicineKorea University Anam HospitalSeoulRepublic of Korea Vanderbilt Center for Bone Biology Vanderbilt University School of MedicineNashvilleTNUSA

Myeloid-derived suppressor cells(MDSCs)are bone marrow(BM)-derived immunosuppressive cells in the tumor microenvironment,but the mechanism of MDSC mobilization from the BM remains *** investigated how BM stromal cell activation by PTH1R contributes to MDSC ***1R activation by parathyroid hormone(PTH)or PTH-related peptide(PTHrP),a tumor-derived counterpart,mobilized monocytic(M-)MDSCs from murine BM without increasing immunosuppressive *** vitro cell-binding assays demonstrated thatα4β1 integrin and vascular cell adhesion molecule(VCAM)-1,expressed on M-MDSCs and osteoblasts,respectively,are key to M-MDSC binding to *** PTH1R activation,osteoblasts express VEGF-A and IL6,leading to Src family kinase phosphorylation in *** inhibitors suppressed PTHrP-induced MDSC mobilization,and Src activation in M-MDSCs upregulated two proteases,ADAM-17 and MMP7,leading to VCAM1 shedding and subsequent disruption of M-MDSC tethering to ***,our data provide the molecular mechanism of M-MDSC mobilization in the bones of tumor hosts.

关键词： MMP7 suppressor regulated

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Lattice Preferred Orientation, Water Content, and Seismic Anisotropy of Orthopyroxene

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Journal of Earth Science 2010年第5期21卷 555-568页

作者： Haemyeong jung Munjae park Sejin jung Jaeseok Lee Tectonophysics Laboratory School of Earth and Environmental Sciences Seoul National University Seoul 151-747 Korea

Lattice preferred orientation （LPO） and seismic anisotropy of orthopyroxene （enstatite） in mantle xenoliths from Spitsbergen, Svalbard, near the Arctic, are studied. LPOs of enstatite were determined using electron backseattered diffraction （EBSD）. We found four types of LPOs of orthopyroxene and defined them as type-AC, -AB, -BC, and -ABC. Type-AC LPO of orthopyroxene is defined as （100） plane aligned subparallel to foliation and [001] axis aligned subparallel to lineation. Type-AB LPO is defined as （100） plane aligned subparallel to foliation and [010] axis aligned subparallel to linea- tion. Type-BC LPO is defined as （010） plane aligned subparallel to foliation and [001] axis aligned subparallel to lineation. Type-ABC LPO is defined as both （100） and （010） planes aligned subparallel to foliation with a girdle distribution of both [100] and [010] axes normal to lineation and [001] axis aligned subparallel to lineation. We report for the first time the type-AB, -BC, and -ABC LPO of orthopyroxerie. We found that the LPO pattern has a correlation with the content of orthopyroxene in the specimen. Nicolet 6700 FTIR （Fourier transformation infrared） study of enstatite showed that type-AC LPO was observed mostly in the samples of enstatite with low water content. It is found that the strength of the LPO of enstatite decreases with increasing water content and has a correlation with the strength of the LPO of olivine： the stronger the LPO of enstatite, the stronger the LPO of olivine. Seismic anisotropy of enstatite was smaller than that of olivine in the same specimen.

关键词： orthopyroxene lattice preferred orientation seismic anisotropy mantle xenolith Spitsbergen FTIR.

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Enhancing Building Facade Image Segmentation via Object-Wise Processing and Cascade U-Net

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Computers, Materials & Continua 2024年第11期81卷 2261-2279页

作者： Haemin jung Heesung park Hae Sun jung Kwangyon Lee Department of Industrial&Management Engineering Korea National University of TransportationChungju27469Republic of Korea Department of Industrial Engineering Yonsei UniversitySeoul03722Republic of Korea Department of Applied Artificial Intelligence Sungkyunkwan UniversitySeoul03063Republic of Korea School of Electronic Engineering Soongsil UniversitySeoul06978Republic of Korea

The growing demand for energy-efficient solutions has led to increased interest in analyzing building facades,as buildings contribute significantly to energy consumption in urban ***,conventional image segmentation methods often struggle to capture fine details such as edges and contours,limiting their effectiveness in identifying areas prone to energy *** address this challenge,we propose a novel segmentation methodology that combines object-wise processing with a two-stage deep learning model,Cascade ***-wise processing isolates components of the facade,such as walls and windows,for independent analysis,while Cascade U-Net incorporates contour information to enhance segmentation *** methodology involves four steps:object isolation,which crops and adjusts the image based on bounding boxes;contour extraction,which derives contours;image segmentation,which modifies and reuses contours as guide data in Cascade U-Net to segment areas;and segmentation synthesis,which integrates the results obtained for each object to produce the final segmentation *** to a dataset of Korean building images,the proposed method significantly outperformed traditional models,demonstrating improved accuracy and the ability to preserve critical structural ***,we applied this approach to classify window thermal loss in real-world scenarios using infrared images,showing its potential to identify windows vulnerable to energy ***,our Cascade U-Net,which builds upon the relatively lightweight U-Net architecture,also exhibited strong performance,reinforcing the practical value of this *** approach offers a practical solution for enhancing energy efficiency in buildings by providing more precise segmentation results.

关键词： Building facade image image segmentation edge detection

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