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Study of alternate cooling and heating treatment induced tumor microvasculature injury

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Chinese Science Bulletin 2010年第2期55卷 172-178页

作者： SHEN YuanYuan ZHANG aili Department of Biomedical Engineering School of Life Sciences and Biotechnology Shanghai Jiao Tong University Shanghai 200240 China

Tumor microvasculature is important to tumor growth, metastasis and thus tumor treatment outcome. The alternate cooling and heating treatment has been confirmed to have advantages over single treatment of cooling or heating. The degree of tumor microvasculature damage induced by the alternate cooling and heating treatment and the mechanisms underlying are studied in this paper. The response of the tumor microvasculature to different treatments including alternate cooling and heating is observed in vivo through confocal microscopy using the nude mice dorsal skin fold tumor chamber model. Results show that alternate cooling and heating has induced much more severe damage to the microvessel structure throughout the entire tumor. Numerical simulations of the mechanical stresses on the tumor vessel wall has found that during the alternate treatment, the vessel wall suffer a rapid chang in thermal stresses in the opposite directions successively, which might caused damage to the peripheral microvasculature and micro-cracks in the central vessels. Reperfusion of blood flow after freezing also led to relatively large stresses on the vessel wall, especially when blood flow re-perfuses quickly during the subsequent heating. The quick increase of stresses on the blood vessel might be one of the key issues causing the blood vessel rupture referring to the experimental observation. The preliminary study has partly revealed the mechanism underlying serious tumor microvasculature damage caused by the alternate cooling and heating treatment.

关键词：肿瘤治疗血管损伤过冷却热诱导加热处理血流灌注显微镜观察微血管

BANDED M-MATRIX SPLITTING PRECONDITIONER FOR RIESZ SPACE FRACTIONAL REACTION-DISPERSION EQUATION

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Journal of Computational Mathematics 2024年第2期42卷 372-389页

作者： Shiping Tang aili Yang Yujiang Wu School of Mathematics and Statistics Lanzhou UniversityLanzhou 730000China School of Mathematics and Statistics Hainan Normal UniversityHaikou 570000China

Based on the Crank-Nicolson and the weighted and shifted Grunwald operators,we present an implicit difference scheme for the Riesz space fractional reaction-dispersion equations and also analyze the stability and the convergence of this implicit difference ***,after estimating the condition number of the coefficient matrix of the discretized scheme,we find that this coefficient matrix is ill-conditioned when the spatial mesh-size is sufficiently *** overcome this deficiency,we further develop an effective banded M-matrix splitting preconditioner for the coefficient *** properties of this preconditioner together with its preconditioning effect are ***,Numerical examples are employed to test the robustness and the effectiveness of the proposed preconditioner.

关键词： Riesz space fractional equations Toeplitz matrix conjugate gradient method Incomplete Cholesky decomposition Banded M-matrix splitting

Effect of Carbon Nanotube on the Oscillating Wear Behaviour of Metal-PTFE Multilayer Composites

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Journal of Wuhan University of Technology(Materials Science) 2018年第5期33卷 1271-1274页

作者： ZOU aili LI Dongsheng School of Mechanical Engineering ＆ Automation Beihang UniversityBeijing 100191China School of Aerospace Engineering Shenyang A erospace UniversityShenyang 110136China

Two kinds of metal-PTFE multilayer composites, which were composed of a steel backing, a middle layer of sintered porous bronze and a surface layer of polytetrafluoroethylene（PTFE） filled by carbon nanotubes（CNTs） or not, were prepared. The wear properties of metal-PTFE multilayer composites oscillating against 45 carbon steel under dry condition were evaluated on an oscillating wear tester, and the effect of CNTs on wear behaviour of metal-PTFE multilayer composites was studied. The results showed that the worn surface of metal-PTFE multilayer composites was characterized by adhesive wear, abrasive wear and fatigue wear. The CNTs greatly increased the adhesion strength of PTFE in the metal-PTFE composites and thereby greatly reduced puck, ploughing, and fatigue failure of PTFE during wearing. The PTFE filled with CNTs prevented direct contact between the mating surfaces and served as fine self-lubricating film, in which the oscillating wear mechanism of the composites was changed to a slightly adhesive wear. Therefore, the CNTs significantly decreased the weight loss and obviously increased the wear resistance of metal-PTFE multilayer composites.

关键词： carbon nanotubes Metal-PTFE composites oscillating wear self-lubricating

Preparation of hollow B–SiO2@TiO2 composites and their photocatalytic performances for degradation of ammonia-nitrogen and green algae in aqueous solution

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Chinese Journal of Chemical Engineering 2019年第10期27卷 2535-2543页

作者： Qin Zhou Hengbo Yin aili Wang Yang Si Faculty of Chemistry and Chemical Engineering Jiangsu UniversityZhenjiang 212013China

Hollow B–SiO2@TiO2 composites were prepared by the wet chemical deposition method starting from TiCl4 and hollow B–SiO2 ***2 layers composed of anatase TiO2 nanoparticles were coated on the surfaces of the hollow B–SiO2 microspheres probably through the formation of Ti—O—Si and Ti—O—B bonds.A great number of—OH groups were also present at the TiO2 coating *** presence of Ti—O—Si bonds and Ti—O—B bonds resulted in the formation of defects in the TiO2 coating layers,which decreased the band gap of the TiO2 coating layers to ca.3.0 eV and endowed the TiO2 coating layers with visible light absorption *** buoyancy hollow B–SiO2@TiO2 composites exhibited high photocatalytic activities for the degradation of ammonia-nitrogen and green *** conversion of ammonia-nitrogen reached 65%when the degradation of ammonia-nitrogen(43 mg·L-1 at pH value of 8)was catalyzed by the B–SiO2@TiO2(100:10)composite under the simulated solar light irradiation at 35°C for 660 *** green algae(5 mg·L-1)were almost completely degraded over the B–SiO@TiO2(100:20)photocatalyst under the visible light irradiation at 35°C for 510 min.

关键词： B–SiO2@TiO 2composites Photocatalysis Ammonia-nitrogen Green algae

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基于双流特征融合的肺结节图像分割网络

现代电子技术 2025年第1期48卷 1-7页

作者：郝胜男庞建华华北理工大学人工智能学院河北唐山063210

为了提高对肺结节的准确分割,文中提出一种CSF-UNet的双骨干网络特征提取方法。使用两种不同侧重的骨干网络并行提取图像特征,通过利用ConvNeXt网络提取局部特征,并结合Swin Transformer网络提取全局特征来提升模型的特征提取能力。提... 详细信息

为了提高对肺结节的准确分割,文中提出一种CSF-UNet的双骨干网络特征提取方法。使用两种不同侧重的骨干网络并行提取图像特征,通过利用ConvNeXt网络提取局部特征,并结合Swin Transformer网络提取全局特征来提升模型的特征提取能力。提出了一种自适应大核融合模块,有效地融合两种不同规格的特征,通过串联两个大核卷积获得更大的感受野和动态选择机制来突出重要的空间区域。在SPPF中融合了ECA通道注意力和密集链接,提出了ESPP模块以进一步挖掘双骨干网络提取的高级语义信息,使网络更加关注重要的特征通道。在LIDC数据集上的实验结果表明,提出的模型在3个指标上优于基本UNet模型以及最近几年其他研究团队提出的针对该数据集的分割网络。最终,CSF-UNet模型实现了78.1%的IoU、87.71%的DSC、87.19%的敏感度和88.23%的精确度。这些结果表明,该模型在肺结节分割方面表现出良好的性能,对医生进行早期肺结节诊断具有重要的临床意义和应用价值。

关键词：肺结节 Transformer ConvNeXt 注意力机制计算机视觉双骨干网络

Hereditarily covering properties of inverse sequence limits

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Frontiers of Mathematics in China 2013年第4期8卷 987-997页

作者： Bin ZHAO aili SONG Jing WEI Department of Mathematics Kashi Teachers College Kashi 844007 China

Let {Xi,πki,ω} be an inverse sequence and X -- lim{Xi,πki,ω）. If each Xi is hereditarily （resp. metaLindelSf, σ-metaLindelSf, σ-orthocompact, weakly suborthocompact, δθ-refinable, weakly θ-refinable, weakly... 详细信息

关键词： Inverse sequence limit hereditarily metaLindelofness hereditarily weakly suborthocompactness hereditarily δθ-refinability hereditarily weakly θ-refinability countable product

Synthesis of Flower-like Manganese Wad and Its Decolorization Performance for Azo Dye Congo Red

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Chemical Research in Chinese Universities 2014年第2期30卷 306-309页

作者： YANG aili WEI Bingqing ZHANG Zhengjun Department of Materials Science and Engineering Tsinghua University Beijing 100085 P.R.China Department of Mechanical Engineering University of Delaware Newark DE 19716 USA

Flower-like manganese wad（MW） with high activity was synthesized via ultrasonic-assisted redox reaction of sole manganese salt MnO4-.MW was characterized by X-ray diffraction（XRD）,scanning electron microscopy（SEM） and X-ray photoelectron spectroscopy（XPS）.The experimental results indicate that the maximum decolorization rate of Congo red（CR） reached above 95％ within 15 min in a wide pH range from 2.0 to *** also show that MW has excellent decolorization performance for azo dye CR which implies potential application for removing dye pollutants from industrial effluents.

关键词： Manganese wad Ultrasonic synthesis Congo red Decolorization

Increasing isobutanol yield by double-gene deletion of PDC6 and LPD1 in Saccharomyces cerevisiae

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Chinese Journal of Chemical Engineering 2016年第8期24卷 1074-1079页

作者： aili Zhang Yang Li Yuhan Gao Hongxing Jin School of Chemical Engineering and Technology Hebei University of Technology

As a new biofuel, isobutanol has received more attentions in recent years. Because of its high tolerance to higher alcohols, Saccharomyces cerevisiae has potential advantages as a platform microbe to produce isobutanol. In this study, we investigated integration effects of enhancing valine biosynthesis by overexpression of ILV2 and BAT2 with eliminating ethanol formation by deletion of PDC6 and decreasing acetyl-Co A biosynthesis by deletion of LPD1 on isobutanol titers. Our results showed that deletion of LPD1 in strains overexpressing BAT2 and ILV2 increased isobutanol titer by 5.3-fold compared with control strain. Additional deletion of PDC6 in lpd1Δ strains carrying overexpressed BAT2 and ILV2 further increased isobutanol titer by 1.5 fold. Overexpression of BAT2 and ILV2 in lpd1Δ strains and pdc6Δ strains decreased ethanol titers. Glycerol titers of the engineered strains did not have greater changes than that of control strain, while their acetic acid titers were higher, perhaps due to the imbalance of cofactors in isobutanol synthesis. Our researches suggest that double-gene deletion of PDC6 and LPD1 in strains overexpressing BAT2 and ILV2 could increase isobutanol production dramatically than single-gene deletion of PDC6 or LPD1. This study reveals the integration effects of overexpression of ILV2/BAT2 and double-gene deletion of LPD1 and PDC6 on isobutanol production, and helps understanding future developments of engineered strains for producing isobutanol.

关键词： Saccharomyces cerevisiae Isobutanol Ethanol Pyruvate decarboxylase

SOCIAL LEARNING WITH TIME-VARYING WEIGHTS

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Journal of Systems Science & Complexity 2014年第3期27卷 581-593页

作者： LIU Qipeng FANG aili WANG Lin WANG Xiaofan Department of Automation Shanghai Jiao Tong Universityand Key Laboratory of System Control and Information ProcessingMinistry of Education of China

This paper investigates a non-Bayesian social learning model, in which each individual updates her beliefs based on private signals as well as her neighbors＇ beliefs. The private signM is involved in the updating process through Bayes＇ rule, and the neighbors＇ beliefs are embodied in through a weighted average form, where the weights are time-varying. The authors prove that agents eventually have correct forecasts for upcoming signals, and all the beliefs of agents reach a consensus. In addition, if there exists no state that is observationally equivalent to the true state from the point of view of all agents, the authors show that the consensus belief of the whole group eventually reflects the true state.

关键词： Consensus social learning social networks time-varying weights.