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Slaughter Performance, Muscle Quality and Nutritional Composition of Duoluo Goats in Sichuan Province

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Agricultural Biotechnology 2024年第2期13卷 12-16页

作者： Mingliang ZHOU Shan WU qian pang Basangzhuoma Minghua CHEN Hualong FU Jinbin MAO Pinggui YANG Sichuan Academy of Grassland Sciences Chengdu 611731China Animal Husbandry Station of Ganzi Tibetan Autonomous Prefecture Kangding 626000China

[Objectives] This study was conducted to understand the biological characteristics of Duoluo goats. [Methods] With male and female Duoluo goats as the research object, related performance indexes were determined and analyzed after slaughter. [Results] The weights of one-year-old male and female Duoluo goats before slaughter were (25.68±2.37) and (24.51±1.97) kg, respectively;the dressing percentages were (43.55±3.24) % and (43.84±3.42) %, respectively;and the net meat percentages were (33.02±2.32) % and (34.19±2.46) %, respectively. (2) The cooked meat rates of male and female Duoluo goats were (65.49±1.42) % and (65.36±1.55) %, respectively;the shearing force was (5.48±1.24) and (5.65±1.02) N, respectively;and the loin-eye muscle areas were (8.95±1.72) and (8.82±1.15) cm 2, respectively. (3) The protein contents of male and female Duoluo goats were (20.07±0.42) and (19.47±1.22) g/100 g, respectively;and the fat contents were (1.30±0.80) % and (2.92±0.55) %, respectively;and the cholesterol contents were (71.76±11.47) and (74.83±2.68) mg/100 g, respectively;(4) The Ca contents of male and female Duoluo goats were (69.53±10.89) and (63.00±4.56) mg/kg, respectively;the Fe contents were (16.73±1.83) and (14.77±0.58) mg/kg, respectively;and the Zn contents were (38.47±3.68) and (31.83±2.22) mg/kg, respectively. (5) In the muscles of male and female Duoluo goats, the contents of essential amino acids were (7.44±0.24) and (7.26±0.41) g/100 g , respectively;the contents of non-essential amino acids were (11.81±0.33) and (11.42±0.67) g/100 g, respectively;and the contents of flavor amino acids were (8.79±0.27) and (8.42±0.57) g/100 g, respectively. [Conclusions] This study lays a foundation for the excavation and utilization of the resource, Duoluo goats.

关键词： Duoluo goat Slaughter Muscle quality Amino acid

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前列腺素E2在骨形成中的作用机制

中华骨质疏松和骨矿盐疾病杂志 2024年第3期17卷 295-302页

作者：周若彤庞倩倩夏维波中国医学科学院、北京协和医学院、北京协和医院内分泌科北京100730

前列腺素E2(prostaglandin E2,PGE2)作为体内一种重要的生物活性物质,通过作用于前列腺素E受体(prostaglandin E receptor,EP),参与内环境稳态的维持。PGE2在骨代谢调控中发挥重要作用,在骨重建的过程中,调控成骨细胞介导的骨形成与破... 详细信息

前列腺素E2(prostaglandin E2,PGE2)作为体内一种重要的生物活性物质,通过作用于前列腺素E受体(prostaglandin E receptor,EP),参与内环境稳态的维持。PGE2在骨代谢调控中发挥重要作用,在骨重建的过程中,调控成骨细胞介导的骨形成与破骨细胞介导的骨吸收,维持动态平衡。在骨形成方面,PGE2/EP轴通过神经调控、机械负荷调控、与体内其他细胞分子间的交互作用,促进成骨细胞增殖分化,维持骨稳态。因此,PGE2在以骨量异常为特征的疾病中发挥关键作用,可能是潜在的治疗靶点。本文对近年来PGE2在骨形成中的调控机制进行综述,并总结现有的临床应用。

关键词：前列腺素E2 骨形成神经调控机械负荷成骨细胞

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机器视觉在圆盘造球机自动化控制中的应用

矿业工程 2024年第1期22卷 62-65页

作者：王亚庞茜孙爽天津市三特电子有限公司天津436056

针对当前圆盘造球生产过程主要依靠现场操作工的主观经验,存在不稳定、不可靠、效率低等问题,开发了自动造球专家系统。系统将机器视觉检测技术应用于自动化控制中,系统能够在线实时分析生球粒径,反馈给控制模型,实时优化并自适应调节... 详细信息

针对当前圆盘造球生产过程主要依靠现场操作工的主观经验,存在不稳定、不可靠、效率低等问题,开发了自动造球专家系统。系统将机器视觉检测技术应用于自动化控制中,系统能够在线实时分析生球粒径,反馈给控制模型,实时优化并自适应调节影响生球质量的模型变量。最终实现稳定造球与自动化生产,为球团厂降本增效。

关键词：自动造球专家系统机器视觉

替雷利珠单抗联合化疗治疗Ⅲb~Ⅳ期非小细胞肺癌的效果

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实用医院临床杂志 2024年第3期21卷 112-116页

作者：刘爽刘倩庞茜茜汤建华张鹤鸣张志华河北北方学院药学院河北省神经药理学重点实验室河北张家口075031 河北北方学院附属第一医院药学部河北张家口075061 河北北方学院附属第一医院呼吸内科河北张家口075061

目的探讨替雷利珠单抗联合化疗治疗晚期非小细胞肺癌(NSCLC)的临床效果。方法选择2021年2月至2022年5月晚期NSCLC患者72例,随机数字表法分为对照组和研究组各36例。对照组给予紫杉醇^(+)卡铂化疗,研究组在对照组的基础上另给予替雷利珠... 详细信息

目的探讨替雷利珠单抗联合化疗治疗晚期非小细胞肺癌(NSCLC)的临床效果。方法选择2021年2月至2022年5月晚期NSCLC患者72例,随机数字表法分为对照组和研究组各36例。对照组给予紫杉醇^(+)卡铂化疗,研究组在对照组的基础上另给予替雷利珠单抗静脉滴注。比较2组患者近期抗肿瘤疗效、肿瘤标志物水平[鳞癌抗原(SCC)、癌胚抗原(CEA)、神经元特异性烯醇化酶(NSE)及糖类抗原125(CA125)]、免疫功能、安全性及预后生存情况。结果研究组客观缓解率、临床控制率高于对照组(P0.05)。研究组累积生存率(72.22%vs 47.22%)高于对照组(P<0.05)。结论替雷利珠单抗联合化疗治疗晚期NSCLC可提高临床疗效,降低肿瘤标志物水平,改善免疫功能,不良反应耐受,并可提高生存率。

关键词：非小细胞肺癌晚期替雷利珠单抗化疗免疫生存预后

Process and Mechanisms of Deep Fluid Effects on Hydrocarbon Generation and Pore Space in Shale:A Case Study from the Mesoproterozoic Xiamaling Formation in the Zhaojiashan Section

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Acta Geologica Sinica(English Edition) 2022年第4期96卷 1342-1352页

作者： MENG Qingqiang pang qian HU Guang JIN Zhijun ZHU Dongya LIU Jiayi ZHANG Chuanwen State Key Laboratory of Shale Oil and Gas Enrichment Mechanisms and Effective Development SINOPECBeijing 100083China Petroleum Exploration and Product Research Institute SinopecBeijing 102206China School of Geoscience and Technology Southwest Petroleum UniversityChengdu 637001China Institute of Energy Peking UniversityBeijing 100871China School of Energy Chinese University of Geosciences(Beijing)Beijing 100083China

Heat carried by deep fluid might greatly affect hydrocarbon generation and pore space in *** intrusion carrying high levels of heat may be a means by which to explore the influence of deep fluid on shale *** study evaluates hydrocarbon generation and analyzed the evolution of shale storage space in the third member of the Xiamaling Formation in the Zhaojiashan section,Hebei Province,based on experimental data such as TOC,SEM,VRo,low-temperature N_(2)adsorption and high-pressure mercury *** results show that the dyke intrusion reduced the shale TOC content drastically―by up to 77%―and also induced instantaneous hydrocarbon generation over a range about 1.4 times the thickness of the ***,the dyke intrusion might transform organic pores in surrounding shales into inorganic *** were two shale porosity peaks:one appeared when VRo=2.0%,caused by the increase of organic pores as thermal maturity increased,the other occurred when the VRo value was between 3%and 4%,caused by the increase of inorganic mineral *** can be concluded that dyke intrusion can be an effective tool with which to study how deep fluid affects instantaneous hydrocarbon generation and pore space in shale.

关键词： deep fluid hydrocarbon generation thermal effect pore Xiamaling Formation

吗啡预处理对缺氧/复氧诱发的心肌细胞线粒体动力学变化的影响

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中国临床药理学杂志 2024年第14期40卷 2023-2027页

作者：高亚云王蕴琦张熙贡美娜逄晓倩田炜徐菁蔓华北理工大学公共卫生学院河北唐山063210 华北理工大学实验动物中心河北唐山063210 河北省器官纤维化重点实验室河北唐山063210

目的探讨吗啡(Mor)对缺氧/复氧(H/R)诱发的心肌H9c2细胞线粒体动力学变化的影响。方法将心肌H9c2细胞分为空白组(正常培养)、模型组(H/R处理)、对照组(5μmol·L^(-1) Mor处理)、实验组(H/R+5μmol·L^(-1) Mor处理)。用透射电子显微镜(... 详细信息

目的探讨吗啡(Mor)对缺氧/复氧(H/R)诱发的心肌H9c2细胞线粒体动力学变化的影响。方法将心肌H9c2细胞分为空白组(正常培养)、模型组(H/R处理)、对照组(5μmol·L^(-1) Mor处理)、实验组(H/R+5μmol·L^(-1) Mor处理)。用透射电子显微镜(TEM)观察线粒体的形态,用活性氧(ROS)、四甲基罗丹明乙酯(TMRE)、线粒体复合体Ⅰ和Ⅲ活性检测试剂盒分别检测ROS含量、线粒体膜电位(MMP)、复合体Ⅰ和Ⅲ活性,用蛋白质印迹法检测线粒体动力学相关蛋白GTP酶动力蛋白相关蛋白1(Drp1)、细胞色素氧化酶Ⅳ亚型(COXⅣ)和线粒体外膜转位酶20(TOM20)蛋白的表达水平。结果实验组细胞核膜光滑完整,线粒体大小一致,嵴排列整齐,空泡化减少,线粒体基质电子密度增加,自噬体数量减少。空白组、模型组、对照组和实验组细胞的ROS含量分别为1.03±0.04、1.53±0.10、1.06±0.06和1.10±0.11,MMP分别为1.00±0.15、0.80±0.16、1.06±0.19和1.00±0.19,复合体Ⅰ活性分别为1.00±0.08、2.28±0.82、1.05±0.26和1.13±0.37,复合体Ⅲ活性分别为1.00±0.09、2.13±0.38、0.83±0.22和0.96±0.11,Drp1蛋白相对表达水平分别为1.00±0.14、1.27±0.07、0.97±0.21和0.93±0.17,线粒体裂变蛋白1(Fis1)蛋白相对表达水平分别为1.00±0.16、1.33±0.18、1.17±0.25和0.99±0.05,COXⅣ蛋白相对表达水平分别为1.00±0.25、0.62±0.08、0.79±0.26和0.97±0.16,TOM20蛋白相对表达水平分别为1.00±0.13、0.67±0.15、0.75±0.13和0.89±0.05。模型组的上述指标与空白组比较,在统计学上差异均有统计学意义(P<0.05,P<0.01,P<0.001,P<0.0001);实验组的上述指标与模型组比较,在统计学上差异均有统计学意义(P<0.05,P<0.01,P<0.001,P<0.0001)。结论吗啡可能通过抑制心肌线粒体自噬和分裂,以及降低呼吸链复合体Ⅰ和Ⅲ的活性减轻氧化应激损伤,进而维持线粒体动力学稳态,减轻H/R诱发的心肌细胞损伤。

关键词：吗啡心肌缺氧/复氧损伤线粒体动力学活性氧

The mechanisms of thermal solidification agent promoting steam diversion in heavy oil reservoirs

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Petroleum Science 2024年第3期21卷 1902-1914页

作者： Zhan-Xi pang qian-Hui Wang qiang Meng Bo Wang Dong Liu State Key Laboratory of Petroleum Resources and Engineering China University of Petroleum(Beijing)Beijing102249China Liaohe Oilfield Institute CNPC ChinaPanjin124000LiaoningChina Henan Oilfield Institute Sinopec ChinaNanyang473400HenanChina Tianjin Branch of China National Offshore Oil Company(CNOOC)Ltd. Tianjin300452China

At high cycles of steam huff&puff,oil distribution in reservoirs becomes stronger heterogeneity due to steam *** solidification agent can be used to solve this *** solution is a lowviscosity liquid at normal temperature,but it can be solidified above 80℃.The plugging degree is up to 99%at 250℃.The sweep efficiency reaches 59.2%,which is 7.3%higher than pure steam *** addition,simultaneous injection of viscosity reducer and/or nitrogen foams can further enhance oil *** mechanism of this technology depends on its strong plugging ability,which changes the flowing pattern of steam to effectively mobilize remaining *** reducer and nitrogen foams further expand the sweep range and extends the effective ***,thermal solidification agent can plug steam channeling paths and adjust steam flowing direction to significantly enhance oil recovery at high cycles of steam huff&puff.

关键词： Heavy oil reservoir Steam huff&puff Steam channeling Steam diversion Plugging performance Mechanism analysis

Energy Spectrum of a Bipartite Complicated-Coupled-Oscillator System

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Communications in Theoretical Physics 2006年第3期45卷 425-428页

作者： pang qian-Jun Physics Department Shanghai Jiao Tong University Shanghai 2000307 China

我们在场一个 bipartitecomplicated-coupled-oscillator 系统的 eigenstate 问题的一般讨论。由一个概括中间的纠缠的状态的使用， Hamiltonian 的表示，特征值和特徵函数是获得的经分解。作为它的申请，我们为 Hamiltonian 的二种特... 详细信息

我们在场一个 bipartitecomplicated-coupled-oscillator 系统的 eigenstate 问题的一般讨论。由一个概括中间的纠缠的状态的使用， Hamiltonian 的表示，特征值和特徵函数是获得的经分解。作为它的申请，我们为 Hamiltonian 的二种特殊状况获得精力光谱。

关键词：能谱双向耦合振荡系统媒介振荡问题

Application of Coordinate-Momentum Intermediate Representation in Solving Eigenstate Problem of a Coupled Oscillator System

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Communications in Theoretical Physics 2005年第3X期44卷 440-444页

作者： pang qian-Jun Department of Physics Shanghai Jiao Tong University Shanghai 200030 China

We study the eigenstate problem of a kind of coupled oscillators in the new quantum mechanical represen tation ｜q, μ, v〉, which is defined as the eigenvector of the operator (μQ + vP), where μ and v are two realparameters. We also use the U operator transformation method to deal with the same problem. We obtain the normally ordered product expressions of U operator and eigenvector. It is shown that the ground state of system Hamiltonian is a squeezed state.

关键词：协同要素媒介表示法转换算法特征向量 Hamiltonian函数