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Intrumer:A Multi Module Distributed Explainable IDS/IpS for Securing Cloud Environment

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Computers, Materials & Continua 2025年第1期82卷 579-607页

作者： Nazreen Banu A S.K.B.sangeetha Department of Computer Science and Engineering SRM Institute of Science and TechnologyVadapalani CampusChennai600026Tamil NaduIndia

The increasing use of cloud-based devices has reached the critical point of cybersecurity and unwanted network *** environments pose significant challenges in maintaining privacy and *** approaches,such as IDS,have been developed to tackle these ***,most conventional Intrusion Detection System(IDS)models struggle with unseen cyberattacks and complex high-dimensional *** fact,this paper introduces the idea of a novel distributed explainable and heterogeneous transformer-based intrusion detection system,named INTRUMER,which offers balanced accuracy,reliability,and security in cloud settings bymultiplemodulesworking together within *** traffic captured from cloud devices is first passed to the TC&TM module in which the Falcon Optimization Algorithm optimizes the feature selection process,and Naie Bayes algorithm performs the classification of *** selected features are classified further and are forwarded to the Heterogeneous Attention Transformer(HAT)*** this module,the contextual interactions of the network traffic are taken into account to classify them as normal or malicious *** classified results are further analyzed by the Explainable prevention Module(XpM)to ensure trustworthiness by providing interpretable *** the explanations fromthe classifier,emergency alarms are transmitted to nearby IDSmodules,servers,and underlying cloud devices for the enhancement of preventive *** experiments on benchmark IDS datasets CICIDS 2017,Honeypots,and NSL-KDD were conducted to demonstrate the efficiency of the INTRUMER model in detecting network trafficwith high accuracy for different *** outperforms state-of-the-art approaches,obtaining better performance metrics:98.7%accuracy,97.5%precision,96.3%recall,and 97.8%*** results validate the robustness and effectiveness of INTRUMER in securing diverse cloud environments against sophisticated cyber threats.

关键词： Cloud computing intrusion detection system transformers and explainable artificial intelligence(XAI)

Navigating the ethical terrain:Off-label and experimental treatments in medical case reports

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World Journal of Methodology 2025年第1期15卷 1-5页

作者： Madhan Jeyaraman Naveen Jeyaraman Swaminathan Ramasubramanian sangeetha Balaji Department of Orthopaedics ACS Medical College and HospitalDr MGR Educational and Research InstituteChennai 600077India Department of Orthopaedics Government Medical CollegeOmandurar Government EstateChennai 600002India

This article explores the ethical considerations surrounding the reporting of offlabel and experimental treatments in medical case reports,with a focus on fields such as oncology,psychiatry,and *** emphasizes the balance between innovation and evidence-based medicine,highlighting the critical role of case reports in disseminating clinical experiences and advancing medical *** discussion delves into the ethical framework guiding case reporting,including principles of patient autonomy,informed consent,non-maleficence,beneficence,justice,and *** such as negative outcome reporting,commercial interests,and the balance between innovation and caution are *** for ethical vigilance,the development of comprehensive guidelines,and the role of regulatory bodies are proposed to ensure patient safety and uphold scientific *** article concludes by underscoring the importance of a collaborative effort among clinicians,researchers,ethicists,and regulatory bodies to foster the responsible advancement of medical science while adhering to the highest ethical standards.

关键词： Ethical considerations patient autonomy Informed consent Non-maleficence Beneficence Transparency Evidence-based medicine

Beyond statistical significance:Embracing minimal clinically important difference for better patient care

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World Journal of Methodology 2025年第1期15卷 33-41页

作者： Naveen Jeyaraman Madhan Jeyaraman Swaminathan Ramasubramanian sangeetha Balaji Sathish Muthu Department of Orthopaedics ACS Medical College and HospitalDr MGR Educational and Research InstituteChennai 600077Tamil NaduIndia Department of Research Methods Orthopaedic Research GroupCoimbatore 641045Tamil NaduIndia Department of Orthopaedics Government Medical CollegeOmandurar Government EstateChennai 600002Tamil NaduIndia Department of Biotechnology Faculty of EngineeringKarpagam Academy of Higher EducationCoimbatore 641021Tamil NaduIndia Department of Orthopaedics Government Medical CollegeKarur 639004Tamil NaduIndia

The minimal clinically important difference(MCID)represents a pivotal metric in bridging the gap between statistical significance and clinical relevance,addressing the direct impact of medical interventions from the patient's *** comprehensive review analyzes the evolution,applications,and challenges of MCID across medical specialties,emphasizing its necessity in ensuring that clinical outcomes not only demonstrate statistical significance but also offer genuine clinical utility that aligns with patient expectations and *** discuss the evolution of MCID since its inception in the 1980s,its current applications across various medical specialties,and the methodologies used in its calculation,highlighting both anchor-based and distribution-based ***,the paper delves into the challenges associated with the application of MCID,such as methodological variability and the interpretation difficulties that arise in clinical *** for the future include standardizing MCID calculation methods,enhancing patient involvement in setting MCID thresholds,and extending research to incorporate diverse global *** steps are critical to refining the role of MCID in patient-centered healthcare,addressing existing gaps in methodology and interpretation,and ensuring that medical interventions lead to significant,patient-perceived improvements.

关键词： Minimal clinically important difference patient-centered care Clinical relevance Global health

BLEND MEMBRANES FOR DIRECT METHANOL AND pROTON EXCHANGE MEMBRANE FUEL CELLS

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Chinese Journal of polymer Science 2012年第4期30卷 548-560页

作者： perumal Bhavani Dharmalingam sangeetha Department of Chemistry Anna UniversityChennai 25India

Sulphonated polystyrene ethylene butylene polystyrene （SpSEBS） prepared with 35% sulphonation was found to be highly elastic and enlarged up to 300%-400% of its initial length. It absorbed over 110% of water by weight. A major drawback of this membrane is its poor mechanical properties which are not adequate for use as polymer electrolytes in fuel cells. To overcome this, SpSEBS was blended with poly（vinylidene fluoride）（pVDF）, a hydrophobic polymer. The blend membranes showed better mechanical properties than the base polymer. The effect of pVDF content on water uptake, ion exchange capacity and proton conductivity of the blend membranes was investigated. This paper presents the results of recent studies applied to develop an optimized in-house membrane electrode assembly （MEA） preparation technique combining catalyst ink spraying and assembly hot pressing. Easy steps were chosen in this preparation technique in order to simplify the method, aiming at cost reduction. The open circuit voltage for the cell with SpSEBS is 0.980 V which is higher compared to that of the cell with Nation 117 （0.790 V）. From this study, it is concluded that a polymer electrolyte membrane suitable for proton exchange membrane fuel cell （pEMFC） and direct methanol fuel cell （DMFC） application can be obtained by blending SpSEBS and pVDF in appropriate proportions. The methanol permeability and selectivity showed a strong influence on DMFC performance.

关键词： Fuel cell Impedance polymer blend proton conductivity.

Unlocking hypoglycemia–associated brain microvascular dysfunction:critical insights from proteomic analysis

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Neural Regeneration Research 2025年第6期20卷 1707-1708页

作者： Siva S.V.p.Sakamuri Anil Sakamuri Department of Chemistry Auburn University at MontgomeryMontgomeryALUSA Vascular Biology Center and Department of Medicine Medical College of Georgia at Augusta UniversityAugustaGAUSA

Hypoglycemia-a critical complication linked to worsened brain function in diabetic subjects:Hypoglycemia is characterized by a decline in circulatory glucose levels below sta nda rd physiological *** hypoglycemia,classified as level 1 hypoglycemia,is defined by blood glucose levels below 70 mg/dL and can be effectively addressed through carbohydrate *** hypoglycemia,denoted by blood glucose levels less than 54 mg/dL,poses a life-threatening risk if left *** with type 1 and type 2 diabetes undergoing insulin treatment are particularly susceptible to hypoglycemia due to impaired counterregulatory mechanisms.

关键词： impaired intake critical

Small molecule inhibitor DDQ-treated hippocampal neuronal cells show improved neurite outgrowth and synaptic branching

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Neural Regeneration Research 2025年第9期20卷 2624-2632页

作者： Jangampalli Adi pradeepkiran priyanka Rawat Arubala p.Reddy Erika Orlov pHemachandra Reddy Department of Internal Medicine Texas Tech University Health Sciences CenterLubbockTXUSA Department of Nutritional Sciences College of Human SciencesTexas Tech UniversityLubbockTXUSA Department of pharmacology&Neuroscience Texas Tech University Health Sciences CenterLubbockTXUSA Department of Neurology Texas Tech University Health Sciences CenterLubbockTXUSA Department of Speech Language and Hearing SciencesTexas Tech University Health Sciences CenterLubbockTXUSA Department of public Health Texas Tech University Health Sciences CenterLubbockTXUSA

The process of neurite outgrowth and branching is a crucial aspect of neuronal development and *** and dendrites,sometimes referred to as neurites,are extensions of a neuron's cellular body that are used to start *** we explored the effects of diethyl(3,4-dihydroxyphenethylamino)(quinolin-4-yl)methylphosphonate(DDQ)on neurite developmental features in HT22 neuronal *** this work,we examined the protective effects of DDQ on neuronal processes and synaptic outgrowth in differentiated HT22cells expressing mutant Tau(mTau)*** investigate DDQ chara cteristics,cell viability,biochemical,molecular,western blotting,and immunocytochemistry were *** outgrowth is evaluated through the segmentation and measurement of neural *** neural processes can be seen and measured with a fluorescence microscope by manually tracing and measuring the length of the neurite *** neuronal processes can be observed and quantified with a fluorescent microscope by manually tracing and measuring the length of the neuronal ***-treated mTau-HT22 cells(HT22 cells transfected with cDNA mutant Tau)were seen to display increased levels of synaptophysin,MAp-2,andβ-***,we confirmed and noted reduced levels of both total and p-Tau,as well as elevated levels of microtubule-associated protein 2,β-tubulin,synaptophysin,vesicular acetylcholine transporter,and the mitochondrial biogenesis protein-pe roxisome prolife rator-activated receptor-gamma coactivator-1α.In mTa u-expressed HT22 neurons,we observed DDQ enhanced the neurite characteristics and improved neurite development through increased synaptic *** findings conclude that mTa u-HT22(Alzheimer's disease)cells treated with DDQ have functional neurite developmental chara *** key finding is that,in mTa u-HT22 cells,DDQ preserves neuronal structure and may even enhance nerve development function with mTa u inhibition.

关键词： diethyl(3 4-dihydroxyphenethylamino)(quinolin-4-yl)methylphosphonate(DDQ) hippocampal neuronal cells HT22 neurite outgrowth neuronal development small molecule

Outlier detection in neutrosophic sets by using rough entropy based weighted density method

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CAAI Transactions on Intelligence Technology 2020年第2期5卷 121-127页

作者： Tamilarasu sangeetha Geetha Mary Amalanathan SCOpE Vellore Institute of TechnologyVelloreIndia

Neutrosophy is the study of neutralities,which is an extension of discussing the truth of *** logic can be applied to any field,to provide the solution for indeterminacy *** of the real-world data have a problem of inconsistency,indeterminacy and *** sets provide a solution for uncertainties,and intuitionistic fuzzy sets handle incomplete information,but both concepts failed to handle indeterminate *** handle this complicated situation,researchers require a powerful mathematical tool,naming,neutrosophic sets,which is a generalised concept of fuzzy and intuitionistic fuzzy *** sets provide a solution for both incomplete and indeterminate *** has mainly three degrees of membership such as truth,indeterminacy and *** values are obtained from the three degrees of membership by cut relation *** items which contrast from other objects by their qualities are *** weighted density outlier detection method based on rough entropy calculates weights of each object and *** the obtained weighted values,the threshold value is fixed to determine *** analysis of the proposed method has been carried out with neutrosophic movie dataset to detect outliers and also compared with existing methods to prove its performance.

关键词： method. entropy incomplete

Understand Students Feedback Using Bi-Integrated CRF Model Based Target Extraction

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Computer Systems Science & Engineering 2022年第2期40卷 735-747页

作者： K.sangeetha D.prabha Department of Computer Science and Engineering Panimalar Engineering CollegeChennai600123India Department of Computer Science and Engineering Sri Krishna College of Engineering and TechnologyCoimbatore641008India

Educational institutions showing interest to find the opinion of the students about their course and the instructors to enhance the teaching-learning *** this,most research uses sentiment analysis to track students’*** sentence-level sentiment analysis focuses on the whole sentence *** studies show that the sentiments alone are not enough to observe the feeling of the students because different words express different sentiments in a *** is a need to extract the targets in a given sentence which helps to find the sentiment towards those *** extraction is the subtask of targeted sentiment *** this paper,we proposed the innovative model to find the targets of the given sentence using Bi-Integrated Conditional Random Fields(CRF).A parallel fusion neural network model is designed to perform this *** evaluate the model using the Michigan dataset and we build a dataset for target extraction from student *** experimental results show that our proposed fusion model achieves better results compared to baseline models.

关键词： Feedback sentimental analysis deeplearning integrated CRF

Unmet supportive care needs in families of children with chronic health conditions: an Australian cross‑sectional study

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World Journal of pediatrics 2023年第12期19卷 1181-1191页

作者： sangeetha Thomas Linda K.Byrne Nicholas p.Ryan Christel Hendrieckx Victoria White School of psychology Faculty of HealthDeakin UniversityMelbourneVIC 3125Australia Department of paediatrics University of MelbourneMelbourneVICAustralia Australian Centre for Behavioural Research in Diabetes MelbourneVICAustralia Institute of Health Transformation Deakin UniversityMelbourneVICAustralia Cancer Council Victoria MelbourneVICAustralia

Background The aim of this study was to identify similarities and diferences in the unmet supportive care needs(USCN)of families of children with major chronic health conditions(CHCs)using a universal need assessment *** A cross-sectional online survey involving parents of children with congenital heart disease(CHD),type 1 diabetes mellitus(T1D),cancer,and asthma diagnosed within the last 5 years recruited via social media and support ***-four items assessing the USCN across six domains(care needs,physical and social needs,informational needs,support needs,fnancial needs,child-related emotional needs)were responded to on a 4-point Likert scale[no need(1)to high need(4)].Descriptive statistics identifed the level of need,and linear regressions identifed factors associated with higher need domain *** to small numbers,the asthma group was excluded from comparisons across *** One hundred and ninety-four parents completed the survey(CHD:n=97,T1D:n=50,cancer:n=39,and asthma:n=8).parents of children with cancer were most likely to report at least one USCN(92%),followed by parents of children with T1D(62%).The fve most commonly reported USCN across CHCs were drawn from four domains:child-related emotional,support,care,and *** need items were included in the top fve needs for all conditions.A higher USCN was associated with a greater frequency of hospital visits and the absence of parental *** Using a universal need assessment tool,this is one of the frst studies to characterize USCN in families of children diagnosed with common *** proportions endorsing diferent needs varied across conditions,the most endorsed needs were similar across the illness *** suggests that support programs or services could be shared across diferent CHCs.

关键词： Children Chronic illness Need assessment Unmet supportive care needs