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Neosporosis: An Overview of Its Molecular Epidemiology and pathogenesis

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Engineering 2020年第1期6卷 10-19页

作者： Asis Khan Jahangheer s.shaik patricia sikorski Jitender p.Dubey Michael E.Grigg Molecular parasitology section Laboratory of Parasitic DiseasesNational Institute of Allergy and Infectious DiseasesNational Institutes of HealthBethesdaMD 20892USA Animal parasitic Disease Laboratory Beltsville Agricultural Research CenterAgricultural Research ServiceUS Department of AgricultureBeltsvilleMD 20705USA

Neospora caninum (N. caninum), a cyst-forming protozoan parasite, is a major cause of bovine abortions and neonatal mortality worldwide. N. caninum has a broad intermediate host range, and its sexual cycle occurs exclusively in canids. Another species of Neospora, Neospora hughesi (N. hughesi), has been identified and causes myeloencephalitis in horses. Although molecular epidemiology studies are in their infancy, the 18s ribosomal RNA (rRNA) and ITs1 regions within the small subunit ribosomal RNA (ssuRNA) and an N. caninum species-specific DNA probe (pNc5) have been used extensively to differentiate Neospora from other closely related apicomplexan parasites. While these repetitive regions have higher sensitivity and specificity than housekeeping or antigen genes, they suffer from low discriminatory power and fail to capture intra-species diversity. similarly, although multiple minisatellite or microsatellite marker studies have shown clear geographic substructures within Neospora, strains are often misclassified due to a convergence in the size of different alleles at microsatellite loci, known as homoplasy. Only one strain, N. caninum Liverpool (Nc-Liv), has been genome sequenced and compared with its closest relative, Toxoplasma gondii (T. gondii). Hence, detailed population genomics studies based on whole-genome sequences from multiple strains worldwide are needed in order to better understand the current population genetic structure of Neospora, and ultimately to determine more effective vaccine candidates against bovine neosporosis. The aim of this review is to outline our current understanding of the molecular epidemiology and genomics of Neospora in juxtaposition with the closely related apicomplexan parasites Hammondia hammondi and T. gondii.

关键词： Neosporosis Molecular epidemiology population genetics Genomics Host response Vaccine

An overview of selected topics in smart grids

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Frontiers in Energy 2016年第4期10卷 441-458页

作者： s. Haft Charan CHERUKURI Balasubramaniyan sARAVANAN school of Electrical Engineering VIT University Vellore 632014 India

smart technologies when used in the tradi- tional grid infrastructure will provide a different environ- ment and working conditions in the grid by bringing the required smartness into the grid, called the smart grid. The smart grid can play a major role in the upcoming days to come because there is a necessity to integrate coordinated renewable energy resources into the grid and to operate the grids at a higher efficiency considering many aspects including reliability of the supply. Apart from this, there is a necessity to manage the demand supply gap in the smart grid by optimally scheduling the generators or by effectively scheduling the demand side resources instead of going for the traditional methods like partial or full load shedding. This paper presents an overview on the present state-of-the-art of smart grid technologies and broadly classifies the papers referred into two major areas, papers based on improvement of operational efficiency in smart grids and papers based on smartness in maintaining the demand supply gap. some of the papers projected in this work also give a brief overview of the necessity of the smart grid.

关键词： smart grid demand side management electric springs operational efficiency

Cost Effective Optimal Task scheduling Model in Hybrid Cloud Environment

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Computer systems science & Engineering 2022年第9期42卷 935-948页

作者： M.Manikandan R.subramanian M.s.Kavitha s.Karthik Department of Computer science&Engineering Sri Krishna College of Engineering and TechnologyCoimbatore641008India Department of Electrical and Electronics Engineering SNS College of TechnologyCoimbatore641035India Department of Computer science&Engineering SNS College of TechnologyCoimbatore641035India

In today’s world, Cloud Computing (CC) enables the users to accesscomputing resources and services over cloud without any need to own the infrastructure. Cloud Computing is a concept in which a network of devices, located inremote locations, is integrated to perform operations like data collection, processing, data profiling and data storage. In this context, resource allocation and taskscheduling are important processes which must be managed based on the requirements of a user. In order to allocate the resources effectively, hybrid cloud isemployed since it is a capable solution to process large-scale consumer applications in a pay-by-use manner. Hence, the model is to be designed as a profit-driven framework to reduce cost and make span. With this motivation, the currentresearch work develops a Cost-Effective Optimal Task scheduling Model(CEOTs). A novel algorithm called Target-based Cost Derivation (TCD) modelis used in the proposed work for hybrid clouds. Moreover, the algorithm workson the basis of multi-intentional task completion process with optimal resourceallocation. The model was successfully simulated to validate its effectivenessbased on factors such as processing time, make span and efficient utilization ofvirtual machines. The results infer that the proposed model outperformed theexisting works and can be relied in future for real-time applications.

关键词： Cost effectiveness hybrid cloud optimal task scheduling virtual machine resource allocation make span

Intralenticular metallic foreign body: a case report

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International Journal of Ophthalmology(English edition) 2011年第3期4卷 326-328页

作者： s C Reddy Department of Ophthalmology Faculty of MedicineUniversity of Malaya

A case of retained intralenticular iron piece with signs of mild anterior uveitis at the time of presentation is reported in a 45 year-old man. His vision improved with topical cycloplegics and corticosteroids. After six months, his vision deteriorated grossly due to cataract formation. He regained good vision following removal of foreign body, extracapsular extraction with posterior chamber intraocular lens implantation. This case highlights the conservative management of the condition till the patient develops cataract resulting in visual disability; and good visual recovery following cataract surgery with intraocular lens implantation.

关键词： intralenticular foreign body anterior uveitis traumatic cataract penetrating eye injury

pharmacopoeia of acute pancreatitis:Is the roster complete?

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World Journal of Gastroenterology 2008年第38期14卷 5938-5939页

作者： Maxim s petrov Department of surgery Nizhny Novgorod State Medical AcademyNizhny Novgorod Russia

Acute pancreatitis is one of the most common diseases in the everyday's practise of gastroenterologists and surgeons. However, the physicians' therapeutic armamentarium is very limited. The present letter to the editor briefly describes the recent evidence from the literature with the aim to optimize a conservative management of patients with acute pancreatitis.

关键词： Acute pancreatitis Conservative treatment Enteral nutrition

BOTTOM,CHARMED MEsONs(B=C=±1)B_c^+=c,B_c^-=cb,similarly for B_c~*'s

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Chinese physics C 2014年第9期38卷 1239-1247页

作者： K.A.Olive K.Agashe C.Amsler M.Antonelli J.-F.Arguin D.M.Asner H.Baer H.R.Band R.M.Barnett T.Basaglia C.W.Bauer J.J.Beatty V.I.Belousov J.Beringer G.Bernardi s.Bethke H.Bichsel O.Biebe E.Blucher s.Blusk G.Brooijmans O.Buchmueller V.Burkert M.A.Bychkov R.N.Cahn M.Carena A.Ceccucci A.Cerr D.Chakraborty M.-C.Chen R.s.Chivukula K.Copic G.Cowan O.Dahl G.D'Ambrosio T.Damour D.de Florian A.de Gouvea T.DeGrand p.de Jong G.Dissertor B.A.Dobrescu M.Doser M.Drees H.K.Dreiner D.A.Edwards s.Eidelman J.Erler V.V.Ezhela W.Fetscher B.D.Fields B.Foster A.Freitas T.K.Gaisser H.Gallagher L.Garren H.-J.Gerber G.Gerbier T.Gershon T.Gherghetta s.Golwala M.Goodman C.Grab A.V.Gritsan C.Grojean D.E.Groom M.Grnewald A.Gurtu T.Gutsche H.E.Haber K.Hagiwara C.Hanhart s.Hashimoto Y.Hayato K.G.Hayes M.Heffner B.Heltsley J.J.Hernandez-Rey K.Hikasa A.Hocker J.Holder A.Holtkamp J.Huston J.D.Jackson K.F.Johnson T.Junk M.Kado D.Karlen U.F.Katz s.R.Klein E.Klempt R.V.Kowalewski F.Krauss M.Kreps B.Krusche Yu.V.Kuyanov Y.Kwon O.Lahav J.Laiho p.Langacker A.Liddle Z.Ligeti C.-J.Lin T.M.Liss L.Littenberg K.s.Lugovsky s.B.Lugovsky F.Maltoni T.Mannel A.V.Manohar W.J.Marciano A.D.Martin A.Masoni J.Matthews D.Milstead p.Molaro K.Monig F.Moortgat M.J.Mortonson H.Murayama K.Nakamura M.Narain p.Nason s.Navas M.Neubert p.Nevski Y.Nir L.pape J.parsons C.patrignani J.A.peacock M.pennington s.T.petcov Kavli IpMU A.piepke A.pomarol A.Quadt s.Raby J.Rademacker G.Raffel B.N.Ratcliff p.Richardson A.Ringwald s.Roesler s.Rolli A.Romaniouk L.J.Rosenberg J L.Rosner G.Rybka C.T.sachrajda Y.sakai G.p.salam s.sarkar F.sauli O.schneider K.scholberg D.scott V.sharma s.R.sharpe M.silari T.sjostrand p.skands J.G.smith G.F.smoot s.spanier H.spieler C.spiering A.stahl T.stanev s.L.stone T.sumiyoshi M.J.syphers F.Takahashi M.Tanabashi J.Terning L.Tiator M.Titov N.p.Tkachenko N.A.Tornqvist D.Tovey G.Valencia G.Venanzoni M.G.Vincter p.Vogel A.Vogt s.p.Wakely W.Walkowiak C.W.Walter D.R.Ward G.Weiglein D.H.Weinberg E.J.Weinberg M.White L.R.Wiencke C.G.Wohl L.Wolfenstein J.Womersley C.L. University of Minnesota School of Physics and Astronomy116 Church St.S.E.MinneapolisMN 55455USA University of Maryland Department of PhysicsCollege ParkMD 20742-4111USA Albert Einstein Center for Fundamental physics Universitat BernCH-3012 BernSwitzerland Lab.Nazionali di Frascati dell'INFN CP 13via E.Fermi40I-00044 Frascati(Roma)Italy Departement de physique Universite de MontrealC.P.6128succ.centre-villeMontreal(Quebec) H3C 3J7Canada pacific Northwest National Laboratory 902 Battelle BoulevardRichlandWA 99352USA Department of physics and Astronomy University of OklahomaNormanOK 73019USA Department of physics University of WisconsinMadisonWI 53706USA physics Division Lawrence Berkeley National Laboratory1 Cyclotron RoadBerkeleyCA 94720USA CERN European Organization for Nuclear ResearchCH-1211 Geneve 23Switzerland Department of physics The Ohio State University191 W.Woodruff Ave.ColumbusOH 43210 COMpAs Group Institute for High Energy PhysicsRU- 142284ProtvinoRussia LpNHE IN2P3-CNRS et Universites de Paris 6 et 7F-75252 ParisFrance Max-planck-Institute of physics 80805 MunichGermany Department of physics University of WashingtonSeattleWA 98195USA Ludwig-Maximilians-Universitat Fakultdt für PhysikSchellingstr.4D-80799 MünchenGermany Enrico Fermi Institute and Department of physics University of ChicagoChicagoIL 60637-1433USA Department of physics Syracuse UniversitySyracuseNY13244USA Department of physics Columbia University538 W.120th StreetNew YorkNY10027 USA High Energy physics Group Blackett LaboratoryImperial CollegePrince Consort RoadLondon SW7 2AZUK Jefferson Lab 12000 Jefferson Ave.Newport NewsVA 23606USA Department of physics University of VirginiaPO Box 400714CharlottesvilleVA 22904USA Fermi National Accelerator Laboratory P.O.Box 500BataviaIL 60510USA Kavli Institute for Cosmological physics University of ChicagoChicagoIL 60637-1433USA Department of physics and Astronomy University of SussexFalmerBrighton BN1 9QHUK Department o

I（Jp） = 0（0-）I, J, p need confirmation.Quantum numbers shown are quark-model predictions.

关键词： B=C HBC B BOTTOM,CHARMED MEsONs B_c cb,similarly for B_c

∧ BARYONs(s=-1,I=0)∧~0=uds

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Chinese physics C 2014年第9期38卷 1452-1470页

We have omitted some results that have been superseded by later experiments. see our earlier editions.

关键词： HBC uds BARYONs I

photosynthetic phenomics of Field-and Greenhouse-Grown Amaranths *** and species Delimits

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plant phenomics 2021年第1期3卷 1-13页

作者： s.D.s.s.sooriyapathirana L.T.Ranaweera H.s.M.Jayarathne T.H.I.Gayathree p.G.R.G.Rathnayake s.I.Karunarathne s.M.N.K.Thilakarathne R.salih C.K.Weebadde C.p.Weebadde Department of Molecular Biology and Biotechnology Faculty of ScienceUniversity of Peradeniya20400 PeradeniyaSri Lanka photosynQ Inc. 325 E Grand River AvenueSuite 331East LansingMI 48823USA Department of plant Soil and Microbial SciencesCollege of Agriculture and Natural ResourcesMichigan State UniversityEast Lansing 48824USA

Consumers hesitate to purchase field-grown shoot-tops of amaranths in sri Lanka,citing the low-cleanliness making growers focus on greenhouse ***,the photosynthetic and growth variations in relation to the organoleptic preference of the greenhouse-grown amaranths in comparison to field-grown counterparts have not been ***,the species delimits of the amaranths in sri Lanka have not been identified,limiting our ability to interpret species-specific production ***,we assessed the common types of amaranths under greenhouse and field *** photosynthesis was measured using a MultispeQ device of the photosynQ phenomic platform,which records chlorophyll fluorescence-based *** shoot-tops were harvested and prepared as dishes according to the typical recipe for amaranths in sri *** dishes were subjected to an organoleptic assessment for the parameters color,aroma,bitterness,texture,and overall *** differences in plant and the shoot-top biomass were also *** markers atpB-rbcL,matk-trnT,and ITs were used to define the species *** field-grown and greenhouse-grown amaranths exhibited species/cultivar-specific photosynthetic *** texture and overall taste of the dishes were different among greenhouse and field-grown *** tasters preferred the texture and the overall taste of the greenhouse-grown *** greenhouse-grown plants also yielded higher shoot-top harvests compared to field-grown *** of the tested markers,ITs defines the delimits of amaranth *** higher organoleptic preference,the appreciable yield levels,unique photosynthetic patterns of the greenhouse-grown amaranths,and species definitions provide the much-needed platform for clean shoot-top production guaranteeing the highest end-user trust.

关键词： guarantee taste limits

Modeling and simulation of circulating fluidized bed reactors applied to a carbonation/calcination loop

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particuology 2014年第4期12卷 116-128页

作者： Rafael A.sánchez Hugo A.Jakobsen Department of Chemical Engineering Norwegian University of Science and Technology7034 TrondheimNorway

A fluid dynamic model for a gas-solid circulating fluidized bed （CFB） designed using two coupled riser reactors is developed and implemented numerically with code programmed in Matlab. The fluid dynamic model contains heat and species mass balances to calculate temperatures and compositions for a carbonation/calcination loop process. Because of the high computational costs required to resolve the three-dimensional phenomena, a model representing a trade-offbetween computational time requirements and accuracy is developed. For dynamic processes with a solid flux between the two reactor units that depends on the fluid dynamics of both risers, a dynamic one-dimensional two-fluid model is sufficient. A two-fluid model using the constant particle viscosity closure for the stress term is used for the solid phase, and an algebraic turbulence model is applied to the gas phase. The numerical model implementa- tion is based on the finite volume method with a staggered grid scheme. The exchange of solids between the reactor units constituting the circulating fluidized bed （solid flux） is implemented through additional mass source/sink terms in the continuity equations of the two phases, For model validation, a relevant experimental analysis provided in the literature is reproduced by the numerical simulations, The numerical analysis indicates that sufficient heat integration between the two reactor units is important for the performance of the circulating fluidized bed system, The two-fluid model performs fairly well for this chemical process operated in a CFB designed as two coupled riser reactors. Further analysis and optimization of the solution algorithms and the reactor coupling strategy is warranted.

关键词： Chemical reactors Fluidization Mathematical modeling Multiphase flow simulation