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硅基pbSe/BaF_2/CaF_2薄膜及其光电特性

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红外与毫米波学报 2001年第2期20卷 154-156页

作者：金进生吴惠桢常勇寿翔 X.M.Fang p.j.mccann 浙江大学物理系浙江杭州310028 中国科学院上海技术物理研究所红外物理国家重点实验室上海200083 School of Electrical & Computer Engineering The University of Oklahoma

采用分子束外延方法在 Si(111)衬底上生长了 pb Se/ Ba F2 / Ca F2 薄膜 ,扫描电镜和 X-光衍射分析显示 ,通过生长 Ba F2 / Ca F2 缓冲层的方法 ,在 Si(111)衬底上外延的 pb Se薄膜晶体质量高 ,pb Se表面光亮 ,无开裂现象发生 ,X-光衍... 详细信息

采用分子束外延方法在 Si(111)衬底上生长了 pb Se/ Ba F2 / Ca F2 薄膜 ,扫描电镜和 X-光衍射分析显示 ,通过生长 Ba F2 / Ca F2 缓冲层的方法 ,在 Si(111)衬底上外延的 pb Se薄膜晶体质量高 ,pb Se表面光亮 ,无开裂现象发生 ,X-光衍射峰峰宽窄 (15 3arcs) .外延生长的 pb Se薄膜被应用于制作光电二极管 ,首次采用热蒸发金属铝膜在 pb Se表面形成 Al- pb Se肖特基结光电二极管 ,获得了比 pb- pb Se肖特基结更为稳定和理想的电流

关键词： pbSe薄膜 BaF2/CaF2缓冲层肖特基结 I-V特性分子束外延光电二极管 Si(111)

Treating amyotrophic lateral sclerosis with allogeneic Schwann cell-derived exosomal vesicles: a case report

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Neural Regeneration Research 2025年第4期20卷 1207-1216页

作者： pascal j.Goldschmidt-Clermont Aisha Khan George jimsheleishvili patricia Graham Adriana Brooks Risset Silvera Alexander j.p.Goldschmidt Damien D.pearse W.Dalton Dietrich Allan D.Levi james D.Guest Miller School of Medicine University of MiamiMiamiFLUSA Stem Cell Institute Miller School of MedicineUniversity of MiamiMiamiFLUSA The Miami project to Cure paralysis Miller School of MedicineUniversity of MiamiMiamiFLUSA Alzady International LLC MiamiFLUSA Neurological Surgery Miller School of MedicineUniversity of MiamiMiamiFLUSA

Schwann cells are essential for the maintenance and function of motor neurons,axonal networks,and the neuromuscular *** amyotrophic lateral sclerosis,where motor neuron function is progressively lost,Schwann cell function may also be ***,important signaling and potential trophic activities of Schwann cell-derived exosomal vesicles have been *** case report describes the treatment of a patient with advanced amyotrophic lateral sclerosis using serial intravenous infusions of allogeneic Schwann cell-derived exosomal vesicles,marking,to our knowledge,the first instance of such *** 81-year-old male patient presented with a 1.5-year history of rapidly progressive amyotrophic lateral *** initial diagnosis,the patient underwent a combination of generic riluzole,sodium phenylbutyrate for the treatment of amyotrophic lateral sclerosis,and *** patient volunteered to participate in an FDA-approved single-patient expanded access treatment and received weekly intravenous infusions of allogeneic Schwann cell-derived exosomal vesicles to potentially restore impaired Schwann cell and motor neuron *** confirmed that cultured Schwann cells obtained from the amyotrophic lateral sclerosis patient via sural nerve biopsy appeared impaired(senescent)and that exposure of the patient’s Schwann cells to allogeneic Schwann cell-derived exosomal vesicles,cultured expanded from a cadaver donor improved their growth capacity in *** a period of observation lasting 10 weeks,during which amyotrophic lateral sclerosis Functional Rating Scale-Revised and pulmonary function were regularly monitored,the patient received weekly consecutive infusions of 1.54×1012(×2),and then consecutive infusions of 7.5×1012(×6)allogeneic Schwann cell-derived exosomal vesicles diluted in 40 mL of Dulbecco’s phosphate-buffered *** of the infusions were associated with adverse events such as infusion reactions(allergic or otherwise)or

关键词： allogeneic amyotrophic lateral sclerosis exosomes infusion neuromuscular junction Schwann cell

Apples to oranges:environmentally derived,dynamic regulation of serotonin neuron subpopulations in adulthood?

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Neural Regeneration Research 2025年第9期20卷 2596-2597页

作者： Christopher j.O’Connell Matthew j.Robson Department of Genetics College of MedicineHarvard UniversityBostonMAUSA james L.Winkle College of pharmacy Division of Pharmaceutical SciencesUniversity of CincinnatiCincinnatiOHUSA Neuroscience Graduate program College of MedicineUniversity of CincinnatiCincinnatiOHUSA

Traumatic brain injury(TBI)is a public health problem with an undue economic burden that impacts nearly every age,ethnic,and gender group across the globe(Capizzi et al.,2020).TBIs are often sustained during a dynamic range of exposures to energetic environmental forces and as such outcomes are typically heterogeneous regarding severity and pathology(Capizzi et al.,2020).

关键词： sustained orange dynamic

Gene therapy for spinal muscular atrophy:perspectives on the possibility of optimizing SMN1 delivery to correct all neurological and systemic perturbations

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Neural Regeneration Research 2025年第7期20卷 2011-2012页

作者： Sharon j.Brown Rafael j.Yáñez-Muñoz Heidi R.Fuller School of pharmacy and Bioengineering Keele UniversityKeeleUK Wolfson Center for Inherited Neuromuscular Disease TORCH BuildingRJAH Orthopaedic HospitalOswestryUK *** Center of Gene and Cell TherapyDepartment of Biological SciencesSchool of Life Sciences and the EnvironmentRoyal Holloway University of LondonEghamUK

Spinal muscular atrophy(SMA)is a genetic condition that results in selective lower motor neuron loss with concomitant muscle weakness and *** genetic cause of SMA was understood in 1995 when loss or impairment of the survival motor neuron 1(SMN1)gene was identified as the main contributing factor(Lefebvre et al.,1995).This,in combination with the discovery that humans have a“back-up”gene,SMN2,which can produce low levels(approximately 10%)of the full-length functional SMN protein,has led to the generation of SMA-specific gene *** was traditionally classified according to age of symptom onset and developmental milestones achieved,with life expectancy and severity varying between ***,SMN2 copy number is used as a proxy for the prediction of disease severity,with higher SMN2 copy number typically being associated with reduced severity of SMA,although this relationship is not absolute:some individuals with low SMN2 copy number have less severe SMA phenotypes and vice ***,the etiology of SMA is further complicated by other factors,such as non-typical nucleotide variants and SMN2-independent modifiers of disease severity.

关键词： atrophy traditionally absolute

Women in visual neural regeneration research

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Neural Regeneration Research 2025年第2期20卷 489-490页

作者： Tonia S.Rex David j.Calkins Vanderbilt Eye Institute Vanderbilt University Medical CenterNashvilleTNUSA

The year 2024 marks the 60^(th)anniversary of Title IX and 25 years since the New York Times revealed bias against female faculty members at the Massachusetts Institute of *** take an opportunity here to examine the state of gender bias in a relatively new yet already prominent field,neural regeneration in the visual system,for which there is a well-defined context useful for this *** National Eye Institute(NEI)provided the first round of research funding for its Audacious Goals Initiative(AGI)on visual neural regeneration in 2013 and the last round in ***,we focus on this *** sources included pubMed,the National Science Foundation(NSF),the NEI,the Blue Ridge Institute for Medical Research and data from the major professional organization for eye and vision research,the Association for Research in Vision and Ophthalmology(ARVO).

关键词： neural visual Times

Generation of brain vascular heterogeneity:recent advances from the perspective of angiogenesis

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Neural Regeneration Research 2025年第7期20卷 2013-2014页

作者： Nathanael j.Lee Ryota L.Matsuoka Department of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Molecular Medicine Cleveland Clinic Lerner College of MedicineCase Western Reserve UniversityClevelandOHUSA

Heterogeneous proper t i es of vascular endothelial cells in the brain:The brain displays large energy dynamics and consumption,and this high level of metabolic demands is fulfilled by a continuous supply of glucose and oxygen through its vascular *** vasculature consists of highly divergent blood vessel branches,giving rise to a dense network of capillaries that supply blood to all cells across the *** elaborated vascular network is thought to develop via angiogenesis,a process in which new blood vessels grow from pre-existing *** capillaries exhibit organotypic features distinct from other tissues and are formed primarily by two major endothelial cell(EC)types:those that form the semi-permeable blood-brain barrier(BBB)and those that develop highly permeable pores known as fenestrae(Matsuoka et al.,2022).The structural and functional differences between BBB and fenestrated vascular ECs represent a fundamental feature of brain vasculature and form the foundation for both brain function and homeostasis.

关键词： angiogenesis homeostasis network

Rapid ongoing decline of Baird’s tapir in Cusuco National park, Honduras

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Integrative Zoology 2012年第4期7卷 420-428页

作者： Niall p.mccann phil M.WHEELER Tim COLES Michael W.BRUFORD School of Biosciences Cardiff UniversityCardiffUK Centre for Environmental and Marine Sciences University of HullScarboroughUK Operation Wallacea Wallace HouseOld BolingbrokeUK

During the International Tapir Symposium 16-21 Oct 2011,the conservation of Baird's tapir(Tapirus baindi)in Honduras received a boost with the signing of a memorandum of understanding between the Minister Direc-tor of the Honduran Instute of Conservation and Forestry(CF)and the Tapir Specialist Group(TSG)Despite this agreement,accelerating levels of hunting and habitat loss contimue to pose a threat to Baird's tapir in *** ongoing study in Cusuco National park in northwestern Honduras has been monitoring changes in population dynamics of Baird's tapir since 2006 through the collection of occupancy *** study has iden-tified an increase in hunting pressure,coinciding with a drastic decline in the encounter rate with Baird's tapir ***,we examine the significance of a range of demographic variables on Baird's tapir occupancy in Cu-suco National park using the software pRESENCE,and simulate the effects of different management strategies on the fiuture dynamics of the population using the stochastic simulation software VORTEX The predictions of the theoretical population models are compared to observed changes in occupancy *** found that non-intervention resulted in the local extinction of Baird's tapir within a very short time fiame,but that various in-tervention models enabled the population to recover to near carrying *** and extinction prob-ability were shown to respond marlkedly to the increase in hunting pressure;and occupancy models supported the fiuture population predictions generated by *** study suggests that immediate intervention is re-quired to reduce hunting pressure to near historical levels to prevent the imminent 1ocal extinction of the species.

关键词： Baird's tapir Honduras population viability analysis pRESENCE VORTEX

Neuroprotection by resveratrol-glucuronide and quercetin-glucuronide via binding to polyphenol-and glycosaminoglycan-binding sites in the laminin receptor

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Neural Regeneration Research 2025年第3期20卷 819-820页

作者： Rayudu Gopalakrishna jennifer Aguilar Emily Lee William j.Mack Department of Integrative Anatomical Sciences Keck School of MedicineUniversity of Southern CaliforniaLos AngelesCAUSA Department of Neurological Surgery Keck School of MedicineUniversity of Southern CaliforniaLos AngelesCAUSA

The dietary polyphenolic compounds resveratrol and quercetin prevent neurodegenerative diseases in experimental models;however, they reach the brain only in nanomolar concentrations in the glucuronidated and sulfated ... 详细信息

关键词： resveratrol molar dated

The supernova remnant CTB 37B and its associated magnetar CXOU j171405.7-381031:evidence for a magnetar-driven remnant

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Research in Astronomy and Astrophysics 2011年第6期11卷 625-630页

作者： j.E.Horvath M.p.Allen Instituto de Astronomia Geofísica e Ciências Atmosféricas-Universidade de So PauloRua do Mato122605508-900 Cidade Universitria So Paulo SPBrazil CEFET So paulo Rua Pedro Vicente 62501109-010Caninde'So Paulo SPBrazil

We discuss the association between the candidate magnetar CXOU j171405.7-381031 and the supernova remnant CTB *** recent detection of the period derivative of the object allowed an estimation of a young characteristic age of only ～ *** value is too small to be compatible even with the minimum radius of the remnant being ≥ 10 pc,the value corresponding to the lower limit of the estimated distance of 10.2 ± 3.5 kpc,unless the true distance happens to be even smaller than the lower *** argue that a consistent scenario for the remnant＇s origin,in which the latter is powered by the energy injected by a young magnetar,is indeed more accurate to explain the young age,and demonstrates its non-standard（***-driven） nature.

关键词： stars:supernova — stars:neutron