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pulsed Microfluid Force-Based On-Chip Modular Fabrication for Liver Lobule-Like 3D Cellular Models

Cyborg and Bionic Systems 2021年第1期2021卷 222-233页

作者： J.Cui h.p.Wang Q.Shi t.Sun Science and technology on Electronic test and Measurement Laboratory North University of ChinaTaiyuan 030051China Intelligent Robotics Institute School of Mechatronical EngineeringBeijing Institute of TechnologyBeijing 100081China Beijing Advanced Innovation Center for Intelligent Robots and Systems Beijing Institute of TechnologyBeijing 100081China Key Laboratory of Biomimetic Robots and Systems(Beijing Institute of technology) Ministry of EducationBeijing 100081China

In vitro three-dimensional(3D)cellular models with native tissue-like architectures and functions have potential as alternatives to human tissues in regenerative medicine and drug ***,it is difficult to replicate liver constructs that mimic in vivo microenvironments using current approaches in tissue engineering because of the vessel-embedded 3D structure and complex cell distribution of the *** paper reports a pulsed microflow-based on-chip 3D assembly method to construct 3D liver lobule-like models that replicate the spatial structure and functions of the liver *** heterogeneous cell-laden assembly units with hierarchical cell distribution are fabricated through multistep photopatterning of different cell-laden *** fluid force interaction by pulsed microflow,the hierarchical assembly units are driven to a stack,layer by layer,and thus spatially assemble into 3D cellular models in the closed liquid chamber of the assembly *** 3D models with liver lobule-like hexagonal morphology and radial cell distribution allow the dynamic perfusion culture to maintain high cell viability and functional expression during long-term culture in *** results demonstrate that the fabricated 3D liver lobule-like models are promising for drug testing and the study of individual diagnoses and treatments.

关键词： culture maintain spatially

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p recision L ivestock F arming: A n international review of scientific and commercial aspects

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International Journal of Agricultural and Biological Engineering 2012年第3期5卷 1-9页

作者： t M Banhazi h Lehr J L Black h Crabtree p Schofield M tscharke D Berckmans National Centre for Engineering in Agriculture University of Southern QueenslandToowoomba CampusQLDAustralia Syntesa(Ltd.) BarcelonaSpain John L Black Consulting PO Box 4021Warrimoo NSWAustralia Farmex Ltd Wyvols Court FarmBasingstoke RoadSwallowfieldReadingUK Silsoe Livest ock Systems Ltd Wrest ParkSilsoeBedsUK M3-BIORES Katholieke Universiteit LeuvenKasteelpark ArenbergLeuvenBelgium

precision Livestock Farming(pLF)is potentially one of the most powerful developments amongst a number of interesting new and upcoming technologies that have the potential to revolutionise the livestock farming *** properly implemented,pLF or Smart Farming could(1)improve or at least objectively document animal welfare on farms;(2)reduce greenhouse gas(GhG)emission and improve environmental performance of farms;(3)facilitate product segmentation and better marketing of livestock products;(4)reduce illegal trading of livestock products;and(5)improve the economic stability of rural ***,there are only a few examples of successful commercialisation of pLF technologies introduced by a small number of commercial companies which are actively involved in the pLF commercialisation *** ensure that the potential of pLF is taken to the industry,it is recommended to:(1)establish a new service industry;(2)verify,demonstrate and publicise the benefits of pLF;(3)better coordinate the efforts of different industry and academic organisations interested in the development and implementation of pLF technologies on farms;and(4)encourage the commercial sectors to assist with professionally managed product development.

关键词： precision Livestock Farming(pLF) smart farming commercialisation scientific issue animal welfare efficiency

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ALLOYING EFFECt OF Ni AND Cr ON thE WEttABILItY OF COppER ON W SUBStRAtE

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Acta Metallurgica Sinica(English Letters) 2008年第5期21卷 369-379页

作者： X.h. Yang p. Xiao S.h. Liang J.t. Zou Z.K. Fan Shaanxi Key Laboratory for Electrical Materials and Infiltration technology School of Materials Science and Engineering Xi＇an University of Technology Xi＇an 710048 China

By the sessile drop technique, the wettability of Cu/W systems with the additions of Ni and Cr has been studied under vacuum atmosphere. Effects of Ni and Cr contents and wetting temperatures on the wettability and the wetting mechanisms of copper on W substrate have been investigated in detail. the results show that the wetting angles of Cu on the W substrate are decreased with an increase in the content of Ni or Cr, and also decrease with raising the wetting temperatures. SEM, EpMA, and X-ray diffraction have been used to analyze the interracial characteristics of the CuNi/W and CuCr/W systems. the results reveal that there is a transition layer about 2- 3μm in the interface of Cu-4.0 wt pct Ni/W, in which the interrnetallic phase Ni4W is precipitated. As to CuCr/W system, no reaction occurs at the interface. the two factors are that the contents of Cr and Ni and the infiltration temperature must be chosen appropriately in order to control the interfacial dissolution and reaction when the Cu- W alloys are prepared by the infiltration method.

关键词： Wettability Contact angles Cu, Cr, Ni W substrate

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Experimentally validated atomistic simulation of the effect of relevant grinding parameters on work piece topography,internal stresses,and microstructure

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Friction 2022年第4期10卷 608-629页

作者： S.J.EDER p.G.GRÜtZMAChER t.SpENGER h.hECKES h.ROJACZ A.NEVOSAD F.hAAS AC2t research Gmbh Viktor-Kaplan-Straße 2/CWiener Neustadt 2700Austria Institute of Engineering Design and product Development TU WienLehárgasse 6-Objekt 7Vienna 1060Austria Institute of production Engineering Graz University of TechnologyKopernikusgasse 24/IGraz 8010Austria tyrolit-Schleifmittelwerke Swarovski K.G. Swarovskistraße 33Schwaz 6130Austria

In this work,we present a fully atomistic approach to modeling a finishing process with the goal to shed light on aspects of work piece development on the microscopic scale,which are difficult or even impossible to observe in experiments,but highly relevant for the resulting material *** a large-scale simulative parametric study,we varied four of the most relevant grinding parameters:the work piece material,the abrasive shape,the temperature,and the infeed *** order to validate our model,we compared the normalized surface roughness,the power spectral densities,the steady-state contact stresses,and the microstructure with proportionally scaled macroscopic experimental *** the grain sizes vary by a factor of more than 1,000 between experiment and simulation,the characteristic process parameters were reasonably reproduced,to some extent even allowing predictions of surface quality degradation due to tool *** the experimentally validated model,we studied time-resolved stress profiles within the ferrite/steel work piece as well as maps of the microstructural changes occurring in the near-surface *** found that blunt abrasives combined with elevated temperatures have the greatest and most complex impact on near-surface microstructure and stresses,as multiple processes are in mutual competition here.

关键词： large-scale molecular dynamics surface quality microstructure Revolutions per minute-Synchronous Grinding(RpM-Synchronous Grinding) tool wear

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A Simple Approach to the Fabrication of Graphene-Carbon Nanotube hybrid Films on Copper Substrate by Chemical Vapor Deposition

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Journal of Materials Science & technology 2015年第5期31卷 479-483页

作者： Nguyen Van Chuc Cao thi thanh Nguyen Van tu Vuong t.Q phuong pham Viet thang Ngo thi thanh tam Institute of Materials Science Vietnam Academy of Science and Technology hanoi University of Science Vietnam National University

In this study,graphene-carbon nanotube（CNt） hybrid films were directly synthesized on polycrystalline copper（Cu） substrates by thermal chemical vapor deposition（CVD） *** films were synthesized on Cu substrate at 1000 ℃ in mixture of gases:argon（Ar）,hydrogen（h2）,and methane（Ch4）.then,carbon nanotubes（CNts） were grown uniformly on the surface of graphene/Cu films at 750 ℃ in mixture of Ar,*** acetylene（C2h2） *** salt FeCl3solution deposited onto the surface of graphene/Cu substrate by spin coating method was used as precursor for the growth of the *** density and quality of the CNts on the surface of graphene/Cu films can be controlled by varying the concentration of FeCl3salt catalyst.

关键词： Graphene Carbon nanotube(CNt) hybrid films Copper

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Electro-optical properties and(E,F) phase diagram of fluorinated chiral smectic liquid crystals

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Chinese physics B 2018年第10期27卷 570-577页

作者： R Zgueb h Dhaouadi t Othman Universite tunis El-Manar Faculte des Sciences de Tunis Laboratoire de physique de la matiere molle et de modelisation electromagnetique (LP3ME) Campus Universitaire Farhat Hached 2092 Tunis Tunisie

Fluorinated smectic liquid crystals each with a biphenyl benzoate rigid core are investigated. Molecular structures of the studied compounds have difference only in fluorine position and the length of the carbon chain. Dielectric relaxation study and electro-optical measurements are carried out with the classical SSFLC geometry. the field-induced phase transitions are studied and the（E,t） phase diagram is established.

关键词： smectic liquid crystal dielectric relaxation electro-optical properties phase transition (E,t)phase diagram

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Notes on M-Estimation in Exponential Signal Models

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Communications in Mathematics and Statistics 2021年第2期9卷 139-151页

作者： Shu Ding Yuehua Wu Kwok-Wai tam School of Economics Hefei University of TechnologyHefeiChina Department of Mathematics and Statistics York UniversityTorontoONCanada Department of Mathematics Portland State UniversityPortlandORUSA

An M-estimation of the parameters in an undamped exponential signal model was proposed in Wu and tam(IEEE trans Signal process 49(2):373–380,2001),and the estimation was shown to be consistent under mild *** this paper,the limiting distributions of the M-estimators are *** is shown that they are asymptotically normally distributed under similar conditions as assumed in Wu and tam(IEEE trans Signal process 49(2):373–380,2001).In addition,a recursive algorithm for computing the M-estimators of frequencies is proposed,and the strong consistency of these estimators is *** Carlo simulation studies using huber’sρfunction are also provided.

关键词： Exponential signal model M-estimation Limiting distribution Recursive algorithm Consistency

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Large signal of h → μτ within the constraints of e_(i) → e_(j)γ decays in the 3-3-1 model with neutral leptons

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Chinese physics C 2022年第12期46卷 106-125页

作者： h.t.hung D.t.Binh h.V.Quyet Department of physics Hanoi Pedagogical University 2Phuc YenVinh Phuc 15000Vietnam Institute of theoretical and Applied Research Duy Tan UniversityHanoi 10000Vietnam Faculty of Natural Science Duy Tan UniversityDa Nang 50000Vietnam

In the framework of the 3-3-1 model with neutral leptons,we investigate lepton-flavor-violating sources based on the higgs mass spectrum,which has two neutral higgs identified with the corresponding ones of the two-higgs-doublet *** note that at the 13teV scale of the LhC,the parameter space regions satisfy the experimental limits of e_(i)→e_(j)γ*** regions depend heavily on the mixing of exotic leptons but are predicted to have large h_(1)^(0)→μτ*** also show that Br(h_(1)^(0)→μτ)can reach a value of 10^(-4).

关键词： higgs boson electroweak interaction beyond the SM LFV decays

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Sensor location in concrete slabs with various layout of opening using modified ‘FEMS-COMAC’ approach

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Earthquake Engineering and Engineering Vibration 2020年第1期19卷 205-222页

作者： h.Vosoughifar p.Manafi Department of Civil and Environmental Engineering University of Hawaii at ManoaHonoluluUSA Department of Civil Engineering South Tehran BranchIslamic Azad UniversityTehranIran

two-way concrete slabs are widely used around the world for the construction of many types of infrastructures and common buildings. the optimal sensor placement(OSp) in slabs with various opening positions is the most important issue in structural health monitoring(ShM) to increase reliability. In this study, a novel approach of OSp was evaluated to obtain the number and placement of sensors using examination of the closed loop performance. the nonlinear finite element(NFE) was used to discretize the mechanism behavior of slab. Multi-Objective Optimization based on the coordinate modal assurance criterion(COMAC) and cost considerations was considered in the optimization processes. All of the analysis, discretization and optimization process was designed and developed as a novel approach in Matlab by the author under the name ‘FEMS-COMAC’(FEM analysis of slab with COMAC). the points in the finite element method(FEM) mesh were classified as line by line information along the slab. the OSp in each line was optimized according to the objective function. the slabs with various width, thickness, aspect ratio and opening position were selected as case studies. the results of the OSp using the COMAC algorithm around the slab openings were compared with the novel ‘FEMS-COMAC’ method. the statistical analysis according Mann-Whitney criteria shows that there were significant differences between them in some of the case studies(mean p-value=0.54).

关键词： two-way concrete slabs openings OSp MAC COMAC

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Scaling of the Density peak with pellet Injection in ItER

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plasma Science and technology 2012年第12期14卷 1035-1040页

作者： p. KLAYWIttAphAt t. ONJUN School of Manufacturing Systems and Mechanical Engineering Sirindhorn International Institute of TechnologyThammasat University

Scalings of the density peak and pellet penetration length in ItER are developed based on simulations using 1.5D BALDUR integrated predictive modeling code. In these simulations, the pellet ablation is described by the Neutral Gas Shielding （NGS） model with grad-B drift effect taken into account. the NGS pellet model is coupled with a plasma core transport model, which is a combination of an MMM95 anomalous transport model and an NCLASS neoclassical transport model. the BALDUR code with a combination of MMM95 and NCLASS models, together with the NGS model, is used to simulate the time evolution of plasma current, ion and electron temperatures, and density profiles for ItER standard type I ELMy h-mode discharges during the pellet injection. As a result, the scaling of the density peak and pellet penetration length at peak density can be established using this set of predictive simulations that covers a wide range of ItER plasma conditions and pellet parameters. the multiple regression technique is utilized in the development of the scalings. It is found that the scaling for density at center is sensitive to both the plasma and pellet parameters; whereas the scalings for density and location of the additional peak are sensitive to the pellet parameters only.

关键词： plasma tokamak fusion pellet injection ItER

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