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定量MR波谱显示颞叶癫病人的背外侧前额叶皮质代谢变化

1988年

作者：埃蒙斯(Emmons h·w·)

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国际医学放射学杂志 2019年第1期 117-117页

作者： q.tan h.Sun w.wang X.wu N.hao X.Su 刘怀贵 Department of Radiology West China Hospital of Sichuan University

摘要目的探讨颞叶癫（tLE）病人背外侧前额叶皮质（DLpFC）的代谢变化。方法对24例tLE病人和22例健康对照者进行定量;h-MRS检查。使用线性组合模型

关键词：背外侧前额叶 tLE 代谢变化

脐血间充质干细胞体外培养方法的改良及其成骨分化能力

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中国组织工程研究与临床康复 2007年第15期11卷 2806-2809页

作者：王琪苟三怀刘岩欧阳跃平席焱海韩庆林邹世恩汤亭亭解放军第二军医大学附属长征医院骨科上海市200003 复旦大学医学院附属妇产科医院上海市200011 上海交通大学医学院附属第九人民医院骨科上海市200011

目的:采用两种改良方法体外分离培养脐血间充质干细胞,并观察其成骨分化能力。方法:实验于2006-05/09在上海交通大学医学院附属第九人民医院骨与关节中心细胞实验室完成。①所用28份脐血标本由复旦大学医学院附属妇产科医院提供,取自足... 详细信息

目的:采用两种改良方法体外分离培养脐血间充质干细胞,并观察其成骨分化能力。方法:实验于2006-05/09在上海交通大学医学院附属第九人民医院骨与关节中心细胞实验室完成。①所用28份脐血标本由复旦大学医学院附属妇产科医院提供,取自足月健康顺产新生儿,产妇和家属均书面同意,实验经医学伦理委员会批准。②采集28份脐血标本,50～90mL/份,枸橼酸抗凝。采集后12h内密度梯度离心法分离出单个核细胞,接种于100mm×20mm培养皿中,细胞浓度为1×1010L-1,置于含体积分数为0.1胎牛血清的α-MEM培养液中原代培养,5～7d后半量换液,后每隔3～4d全量换液一次。③细胞贴壁后,分两组予以改良培养。改良1组10份,当培养皿底圆形巨核细胞融合、梭形成纤维样细胞脱落时将细胞悬液移入新的培养皿中培养;改良2组18份,待培养皿底圆形巨核细胞渐渐占据优势时,将培养基更换为含体积分数为0.15小牛血清的α-MEM,当圆形巨核细胞大部脱落后换回含体积分数为0.1胎牛血清的α-MEM培养基。成纤维样细胞融合至80%～90%时胰酶消化,按1∶2或1∶3传代培养。④显微镜下观察脐血间充质干细胞的形态。取第5代脐血间充质干细胞,采用流式细胞仪测定细胞免疫表型,以碱性磷酸酶法检测成骨分化能力。结果:①28份脐血间充质干细胞中,共20份原代培养中出现贴壁细胞(改良1组6份,改良2组14份),其中13份培养出能融合且可稳定传代的成纤维样细胞(改良1组4份,改良2组9份),成功率46.4%。②原代培养5～7d后贴壁细胞呈梭形成纤维样细胞和圆形巨核细胞。改良1组与2组于原代培养5周可见成纤维样细胞集落,细胞形态与骨髓间充质干细胞相似,呈较均一的长梭形,传至22代形态无明显变化。③可强烈表达CD29、CD105等间充质干细胞表面标志,而不表达CD34、CD45和CD106等造血干细胞和内皮细胞标志。④成骨诱导1周,脐血间充质干细胞可分化为成骨细胞,碱性磷酸酶染色呈阳性。结论:脐血中存在的单个核细胞经过改良培养后,可提高脐血间充质干细胞的培养成功率。脐血间充质干细胞具有与其他来源的单个核细胞类似的表型及成骨分化潜能,且易于体外扩增、传代稳定。

关键词：细胞培养技术骨生成胎血间质干细胞

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Data Assimilation of Dust Aerosol Observations for CUACE/Dust Forecasting System

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Data Assimilation of Dust Aerosol Observations for CUACE/Dus...

Dynamics of self-hybridized exciton–polaritons in 2D halide perovskites

第三届中日韩气象学术会议

作者： t.Niu~1 S.L.Gong~(2 1) G.F.Zhu~3 h.L.Liu~1 X.q.hu~4 C.h.Zhou~1 Y.q.wang~1 ~1Center for Atmosphere watch & Services(CAwAS)Chinese Academy of Meteorological Sciences China Meteorological Administration(CMA) Beijing 100081 China ~2Air quality Research Division Science & technology Branch Environment Canada 4905 Dufferin Street toronto Ontario M3h 5t4 Canada ~3State Key Laboratory of Severe weather Chinese Academy of Meteorological Sciences China Meteorological Administration(CMA) Beijing 100081 China ~4National Satellite Meteorological Center China Meteorological Administration(NSMC/CMA) Beijing 100081 China

＜正＞A data assimilation system （DAS） was developed for the Chinese Unified Atmospheric Chemistry Environment-Dust （CUACE/Dust） forecast system and applied in the operational forecasts of sand and dust storm （SDS） in spring *** system is based on a three dimensional variational method （3D-Var） and uses extensively the measurements of surface visibility and dust loading retrieval from the Chinese geostationary satellite *** results show that a major improvement to the capability of CUACE/Dust in forecasting the short-term variability in the spatial distribution and intensity of dust concentrations has been achieved,especially in those areas far from the source *** seasonal mean threat Score （tS） over the East Asia in spring 2006 increased from 0.22 to 0.31 by using the data assimilation system, a 41% *** assimilation results usually agree with the dust loading retrieved from FY-2C and visibility distribution from surface meteorological stations, which indicates that the 3D-Var method is very powerful for the unification of observation and numerical modeling results.

关键词： data assimilation 3D-Var method visibility satellite dust loading

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Light(Science & Applications) 2024年第1期13卷 13-22页

作者： Surendra B.Anantharaman Jason Lynch Christopher E.Stevens Christopher Munley Chentao Li Jin hou hao Zhang Andrew torma thomas Darlington Francis Coen Kevin Li Arka Majumdar pJames Schuck Aditya Mohite hayk harutyunyan Joshua R.hendrickson Deep Jariwala Department of Electrical and Systems Engineering University of PennsylvaniaPhiladelphiaPA19104USA KBR Inc. BeavercreekOH45431USA Air Force Research Laboratory Sensors DirectorateWright-Patterson Air Force BaseOH45433USA Department of physics University of WashingtonSeattleWA98195USA Department of physics Emory UniversityAtlantaGA30322USA Department of Chemical and Biomolecular Engineering Rice UniversityHoustonTX77005USA Department of Materials Science and Nanoengineering Rice UniversityHoustonTX77005USA Applied physics program Smalley‐Curl InstituteRice UniversityHoustonTX77005USA Department of Mechanical Engineering Columbia UniversityNew YorkNY10027USA Department of Electrical and Computer Engineering University of WashingtonSeattleWA98195USA

Excitons,bound electron–hole pairs,in two-dimensional hybrid organic inorganic perovskites(2D hOIps)are capable of forming hybrid light-matter states known as exciton-polaritons(E–ps)when the excitonic medium is confined in an optical *** the case of 2D hOIps,they can self-hybridize into E–ps at specific thicknesses of the hOIp crystals that form a resonant optical cavity with the ***,the fundamental properties of these self-hybridized E–ps in 2D hOIps,including their role in ultrafast energy and/or charge transfer at interfaces,remain ***,we demonstrate that>0.5µm thick 2D hOIp crystals on Au substrates are capable of supporting multiple-orders of self-hybridized E–p *** E–ps have high q factors(>100)and modulate the optical dispersion for the crystal to enhance sub-gap absorption and *** varying excitation energy and ultrafast measurements,we also confirm energy transfer from higher energy E–ps to lower energy E–***,we also demonstrate that E–ps are capable of charge transport and transfer at *** findings provide new insights into charge and energy transfer in E–ps opening new opportunities towards their manipulation for polaritonic devices.

关键词： charge polar excitation

Interaction studies between rice and pyricularia grisea in Jilin province,***

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Interaction studies between rice and Pyricularia grisea in J...

第十一届全国植物基因组学大会

作者： J.C.wang~(1*),Y.L.Li~2,J.w.wen~1,L.J.Meng~2,w.p.Liu~1,Y.M.Jia~2,S.R.Yan~1,J.C.pang~1,J.q.wang~3,J. p.Ren~1 1 Institute of plant protection,Jilin Academy of Agricultural Sciences,Changchun City,130124,Jilin pro.,p.R. China. 2 tonghua Academy of Agricultural Sciences Research,Meihekou City,Jilin province,135007,p.R.China. 3 Station of Agricultural technology Extention of Yanhe town,Yushu City,Jilin province,130421,p.R.China

Jilin province is an important Japonica-type rice producing areas in Northeast China,and rice blast caused by pyricularia grisea,is a serious disease in local *** the molecular biotechnology and conventional agricultu...

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声表面波器件用的压电陶瓷材料

压电与声光 1979年第5期 54-58页

作者： h.Schichl ,w.Christoffers ,h·hanisch ,邵维娟

如果一种材料被认为适合于作声表面波（SAw）器件,则材料的技术性能就必须满足一些基本的要求.这就是在+20到+60℃温度范围内低的声速温度系数(tC<70×10-6/℃)、能保持阻抗高于50欧的低介电常数（ε<300）、能提供高清晰度电极结构的... 详细信息

如果一种材料被认为适合于作声表面波（SAw）器件,则材料的技术性能就必须满足一些基本的要求.这就是在+20到+60℃温度范围内低的声速温度系数(tCpb(Cu1/4Nb3/4)O3-ph(Ni1/4Nb3/4)O3-pbtiO3-pbZrO3的三角晶相所得到的实验结果.pb(Cu1/4Nb3/40.067(Li1/4)Nb3/4)0.023ti0.024Zr0.67O3+0.5重量%MnO2组成具有适合于SAw器件应用的最佳材料技术性能,其性能如下:耦合系数Kp=0.26介电常数ε=285机械品质因素q=3600tCε=4.7×10-3/℃tCv=50×10-6/℃老化速率V≤0.5×10-3/+年ε≤2.2%/+年在这种组成的陶瓷基体上已经实现了电视中频（f0=36兆赫）用的声表面波滤波器.与计算曲线相比较可知滤波器的通带、陷波的频率和斜率都很合适.只有陷波衰减和远端选择性在计算曲线和测量曲线之间有差别.

关键词：机械品质因素三角晶系 tC 相界耦合系数耦合因数介电常数电容率介电性质温度系数

A scenario for high accuracy τ mass measurement at BEpC-Ⅱ

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Chinese physics C 2012年第7期36卷 573-577页

作者： M. N. Achasov V. E. Blinov 蔡啸傅成栋 F. A. harris q. Liu 莫晓虎 N. Yu. Muchnoi I. B. Nikolaev 秦庆 A. G. Shamov K. Yu. todyshev 王贻芳张建勇 Budker Institute of Nuclear physics Siberian Branch of the Russian Academy of Sciences11 Lavrentyev Novosibirsk 630090 Russia Institute of high Energy physics Chinese Academy of Sciences University of hawaii HonoluluHI 96822 USA

Scenarios for the τ mass measurement at the upgraded Beijing Electron-positron Collider （BEpC- II ） are studied. A nested minimization procedure is used to optimize the data taking plan. It is found that by using five energy points with the total integrated luminosity of 100 pb-1, the τ mass can be determined with a statistical error of 50 keV.

关键词： τ mass scan optimization uncertainty

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DiGeorge综合征伴SAphO性骨髓炎和类肉瘤样皮炎1例

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世界核心医学期刊文摘（儿科学分册） 2006年第A10期2卷 27-28页

作者： Jyonouchi h. Lien K.w. Aguila h. 刘莉 Division of pulmonary Allergy/Immunology and Infectious Diseases Department of Pediatrics University of Medicine and Dentistry of New Jersey (UMDNJ)- NewJersey Medical School 185 South Orange Ave. Newark NJ 07101- 1709 United States

we report the development and spontaneous resolution of annular erythematous skin lesions consistent with sarcoid dermatitis in a child with DiGeorge syndrome (DGS) carrying the 22q11.2 microdeletion. the skin lesion developed after she was treated with isoniazid (INh) following exposure to active tuberculosis (tB). After resolution of the skin lesions, this child developed sterile hyperplastic osteomyelitis consistent with SAphO (synovitis, acne, pustulosis, hyperostosis, and osteitis) osteomyelitis in her right mandible triggered by an odontogenic infection. this child had congenital heart disease, dysmorphic facies, recurrent sinopulmonary infection, gastroesophgeal re- flux disease, scoliosis, reactive periostitis, and developmental delay. She had a low CD4 and CD8 t cell count with a normal 4/8 ratio, but normal cell proliferation and t cell cytokine production in response to mitogens. when she was presented with sterile osteomyelitis of right mandible, she revealed polyclonal hypergammaglobulinemia with elevated erythrocyte sedimentation rate (ESR)/ angiotensin converting enzyme (ACE) levels, but negative CRp. Autoimmune and sarcoidosis workup was negative. Inflammatory parameters gradually normalized following resolution of odontogenic infection and with the use of non- steroidal anti- inflammatory drugs (NSAIDs). the broad clinical spectrum of DGS is further expanded with the development of autoimmune and inflammatory complications later in life. this case suggests that patients with the DGS can present with unusual sterile inflammatory lesions triggered by environmental factors, further broadening the clinical spectrum of this syndrome.

关键词：肉瘤样 DiGeorge SAphO 脊柱侧凸颜面畸形活动性结核环状红斑皮损消退胃食管反流

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Mechanisms mediating the effects of alcohol and hIV anti-retroviral agents on mtORC1,mtORC2 and protein synthesis in myocytes

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world Journal of Biological Chemistry 2012年第6期3卷 110-120页

作者： Ly q hong-Brown Abid A Kazi Charles h Lang Department of Cellular and Molecular physiology Penn State College of MedicineHersheyPA 17033United States

Alcoholism and acquired immune deficiency syndrome are associated with severe muscle *** impairment in nitrogen balance arises from increased protein degradation and a decreased rate of protein *** regulation of protein synthesis is a complex process involving alterations in the phosphorylation state and protein-protein interaction of various components of the translation machinery and mammalian target of rapamycin(mtOR) *** review describes mechanisms that regulate protein synthesis in cultured C2C12 myocytes following exposure to either alcohol or human immunodeficiency virus antiretroviral *** attention is given to the upstream regulators of mtOR complexes and the downstream targets which play an important role in *** a better understanding of these molecular mechanisms could have important implications for preventing changes in lean body mass in patients with catabolic conditions or illnesses.

关键词： AMp-activated protein kinase/tuberous sclerosis complex 2/Ras homolog enriched in brain Rag Gtpases phospholipase D Mitogen-activated protein kinase translation initiation Elongation