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Chinese Optics Letters 2013年第5期11卷 28-32页

作者： Y.K.Lam w.C.Situ p.w.m.tsang Department of Electronic Engineering City University of Hong Kong

A method for fast and low bit-rate compression of digital holograms based on a new vector quantization （VQ） method known as the skip-dimension VQ （SDVQ） is proposed. Briefly, a complex hologram is converted into a real off-axis hologram, and partitioned into a set of image vectors. The image vectors are passed into a graphic processing unit （GpU）, and compressed through SDVQ into a set of code indices considerably smaller in data size than the source hologram. Experimental evaluation reveals that our scheme is capable of compressing a digital hologram to a compression ratio of over 500 times, in approximately 20-22 ms.

关键词： GpU Fast compression of computer-generated holographic images based on a GpU-accelerated skip-dimension vector quantization method VQ

Enhancement on the generation of sampled phase-only holograms

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Chinese Optics Letters 2015年第6期13卷 27-30页

作者： p.w.m.tsang Y.T.Chow T.-C.poon Department of Electronic Engineering City University of Hong Kong Hong KongSpecial Administrative Region (SAR) Bradley Department of Electrical and Computer Engineering

past research has demonstrated that if the intensity image of an object is uniformly down-sampled and converted into a Fresnel hologram, the phase component alone will be sufficient to reconstruct the source image. However, due to down-sampling, the edge and line patterns are degraded heavily. In this Letter, we propose an enhance- ment on the parent method by incorporating an adaptive down-sampling lattice. A hologram generated with our proposed method, which is referred to as the edge-enhanced sampled phase-only hologram, preserves favorable visual quality on both the shaded regions as well as the edge patterns of the object image.

关键词： Lithography Signal sampling

Review of fast methods for point-based computer-generated holography [Invited]

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photonics Research 2018年第9期6卷 837-846页

作者： p.w.m.tsang T.-C.pOON Y.m.wU Department of Electronic Engineering City University of Hong Kong Bradley Department of Electrical and Computer Engineering Virginia Tech

Computer-generated holography(CGH) is a technique for converting a three-dimensional(3D) object scene into a two-dimensional(2D), complex-valued hologram. One of the major bottlenecks of CGH is the intensive computation that is involved in the hologram generation process. To overcome this problem, numerous research works have been conducted with the aim of reducing arithmetic operations involved in CGH. In this paper,we shall review a number of fast CGH methods that have been developed in the past decade. These methods,which are commonly referred to as point-based CGH, are applied to compute digital Fresnel holograms for an object space that is represented in a point cloud model. while each method has its own strength and weakness,trading off conflicting issues, such as computation efficiency and memory requirement, they also exhibit potential grounds of synergy. we hope that this paper will bring out the essence of each method and provide some insight on how different methods may crossover into better ones.

关键词：全息术计算机技术发展现状三维技术

Fast reconstruction of digital holograms for extended depths of field

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Chinese Optics Letters 2016年第7期14卷 34-37页

作者： p.w.m.tsang T.-C.poon T.Kim Y.S.Kim Department of Electronic Engineering City University of Hong Kong Bradley Department of Electrical and Computer Engineering Virginia Tech Dept of Optical Engineering Sejong University

past research has demonstrated that a static, three-dimensional （3D） object scene can be directly recorded as a complex digital hologram. However, numerical reconstruction of the object scene, which may comprise multiple sections located at unknown distances from the hologram, is a complicated and computation-intensive process. To the best of our knowledge, we propose, for the first time, a low complexity method that is capable of recon- structing a complex hologram, such that sections at different depths in the 3D object scene can be automatically reconstructed at the correct focal distances and merged into a single image for an extended depth of field. we demonstrate an order of magnitude increase of the depth of field for binary objects. with the use of a graphical processing unit, the reconstruction of a 512 × 512 complex hologram can be accomplished in about 100 ms, equivalent to around 10 frames per second.

关键词： Lithography

Glia-to-neuron reprogramming to the rescue?

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Neural Regeneration Research 2025年第5期20卷 1395-1396页

作者： Jack w.Hickmott Cindi m.morshead Department of Surgery University of TorontoTorontoONCanada Donnelly Centre for Cellular and Biomolecular Research TorontoONCanada Institute of Biomedical Engineering University of TorontoTorontoONCanada The KITE Research Institute Toronto Rehabilitation InstituteUniversity Health NetworkTorontoONCanada

Over the last two decades,the dogma that cell fate is immutable has been increasingly challenged,with important implications for regenerative *** brea kth rough discovery that induced pluripotent stem cells could be generated from adult mouse fibroblasts is powerful proof that cell fate can be *** exciting extension of the discovery of cell fate impermanence is the direct cellular reprogram ming hypothesis-that terminally differentiated cells can be reprogrammed into other adult cell fates without first passing through a stem cell state.

关键词： programming passing proof

Dynamic modeling of a three-dimensional braided composite thin plate considering braiding directions

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Applied mathematics and mechanics(English Edition) 2025年第1期46卷 123-138页

作者： Chentong GAO Huiyu SUN Jianping GU w.m.HUANG College of Aerospace Engineering Nanjing University of Aeronautics and Astronautics School of mechanical and Aerospace Engineering Nanyang Technological University Jiangsu Key Laboratory of Advanced Structural materials and Application Technology School of Materials Science and EngineeringNanjing Institute of Technology

Currently, there are a limited number of dynamic models available for braided composite plates with large overall motions, despite the incorporation of three-dimensional(3D) braided composites into rotating blade components. In this paper, a dynamic model of 3D 4-directional braided composite thin plates considering braiding directions is established. Based on Kirchhoff's plate assumptions, the displacement variables of the plate are expressed. By incorporating the braiding directions into the constitutive equation of the braided composites, the dynamic model of the plate considering braiding directions is obtained. The effects of the speeds, braiding directions, and braided angles on the responses of the plate with fixed-axis rotation and translational motion, respectively, are investigated. This paper presents a dynamic theory for calculating the deformation of 3D braided composite structures undergoing both translational and rotational motions. It also provides a simulation method for investigating the dynamic behavior of non-isotropic material plates in various applications.

关键词： three-dimensional (3D) braided composite braiding direction composite thin plate large overall motion dynamic model O313.7

A novel method for clustering cellular data to improve classification

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Neural Regeneration Research 2025年第9期20卷 2697-2705页

作者： Diek w.wheeler Giorgio A.Ascoli Center for Neural Informatics Structures&PlasticityKrasnow Institute for Advanced Study Bioengineering Department Volgenau School of Engineering George mason University FairfaxVAUSA

many fields,such as neuroscience,are experiencing the vast prolife ration of cellular data,underscoring the need fo r organizing and interpreting large datasets.A popular approach partitions data into manageable subsets via hierarchical clustering,but objective methods to determine the appropriate classification granularity are *** recently introduced a technique to systematically identify when to stop subdividing clusters based on the fundamental principle that cells must differ more between than within *** we present the corresponding protocol to classify cellular datasets by combining datadriven unsupervised hierarchical clustering with statistical *** general-purpose functions are applicable to any cellular dataset that can be organized as two-dimensional matrices of numerical values,including molecula r,physiological,and anatomical *** demonstrate the protocol using cellular data from the Janelia mouseLight project to chara cterize morphological aspects of neurons.

关键词： cellular data clustering dendrogram data classification Levene's one-tailed statistical test unsupervised hierarchical clustering

Genistein:a possible solution for the treatment of Alzheimer’s disease

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Neural Regeneration Research 2025年第10期20卷 2903-2905页

作者： Karolina pierzynowska Bartosz Karaszewski Grzegorz węgrzyn Department of molecular Biology University of GdanskGdanskPoland Gdansk Polandand Department of Adult NeurologyFaculty of MedicineMedical University of GdanskGdanskPoland

Neurodegenerative diseases are defined as disorders resulting from the slow and progressive loss of function and eventual death of neural cells that result from the primary pathology of nervous *** can lead to severe nervous system dysfunction,eventually affecting multiple organs and *** hundred neurodegenerative diseases have been described,and owing to their prevalence,severity.

关键词： organs Alzheimer death

"Scarless world or scar-less world":expedition on new perspectives on management of post-burn hypertrophic scar

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Burns & Trauma 2016年第2期4卷 68-70页

作者： Cecilia w.p.Li-tsang Department of Rehabilitation Sciences The Hong Kong Polytechnic UniversityHung HomHong KongChina

Hypertrophic scar has always been the top priority of post-burn *** from multiple disci-plines have dedicated enormous efforts expanding the knowledge in understanding the etiology of hypertrophic scar formation and establishing the scientific evidence of effective management of hypertrophic *** devotion and pursuit of these scientists and clinicians has been especially meaningful for the population in Asia since it has been well proven that hypertrophic scar was endemic to the Asian population comparing to the *** early intervention,functional outcomes and long-term quality of life for people with extensive burn injuries have been investigated by different researchers and further substantiate the importance of long-term continuum of rehabilitation programs[1,2].

关键词： scar injuries establishing

Heterogeneity of mature oligodendrocytes in the central nervous system

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Neural Regeneration Research 2025年第5期20卷 1336-1349页

作者： Chao weng Adam m.R.Groh moein Yaqubi Qiao-Ling Cui Jo Anne Stratton G.R.wayne moore Jack p.Antel Neuroimmunology Unit Montreal Neurological Institute-HospitalDepartment of Neurology and NeurosurgeryMcGill UniversityMontrealQCCanada Department of Neurology Renmin Hospital of Wuhan UniversityWuhanHubei ProvinceChina

mature oligodendrocytes form myelin sheaths that are crucial for the insulation of axons and efficient signal transmission in the central nervous *** evidence has challenged the classical view of the functionally static mature oligodendrocyte and revealed a gamut of dynamic functions such as the ability to modulate neuronal circuitry and provide metabolic support to *** the recognition of potential heterogeneity in mature oligodendrocyte function,a comprehensive summary of mature oligodendrocyte diversity is *** delve into early 20th-century studies by Robertson and Río-Hortega that laid the foundation for the modern identification of regional and morphological heterogeneity in mature ***,recent morphologic and functional studies call into question the long-assumed homogeneity of mature oligodendrocyte function through the identification of distinct subtypes with varying myelination ***,modern molecular investigations,employing techniques such as single cell/nucleus RNA sequencing,consistently unveil at least six mature oligodendrocyte subpopulations in the human central nervous system that are highly transcriptomically diverse and vary with central nervous system *** and disease related mature oligodendrocyte variation denotes the impact of pathological conditions such as multiple sclerosis,Alzheimer's disease,and psychiatric ***,caution is warranted when subclassifying mature oligodendrocytes because of the simplification needed to make conclusions about cell identity from temporally confined *** studies leveraging advanced techniques like spatial transcriptomics and single-cell proteomics promise a more nuanced understanding of mature oligodendrocyte *** research avenues that precisely evaluate mature oligodendrocyte heterogeneity with care to understand the mitigating influence of species,sex,central nervous system region,age,and disease,

关键词： aging central nervous system diseases electron microscopy heterogeneity immunohistochemistry myelin sheath natural history neuroglia oligodendroglia single-cell gene expression analysis