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Modeling the mechanics of calcium regulation in T lymphocyte:A finite element method approach

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International Journal of Biomathematics 2020年第5期13卷 149-169页

作者： parvaiz Ahmad naik School of Mathematics and Statistics Xi'an Jiaotong Unirersity Xi'an Shaanxi 710049P.R.China

Changes in cellular Ca2+concentration control a variety of physiological activities including hormone and neurotransmitter release,muscular contraction,synaptic plas-ticity,ionic channel permeability,apoptosis,enzyme activity,gene transcription and reproduction ***-temporal Ca2+dynamics due to Ca2 t release,buffering and re-uptaking plays a central role in studying the Ca2+regulation in T *** most cases,Ca2+has its major signaling function when it is elevated in the cytosolic *** this paper,a two-dimensional mathematical model to study spatiotemporal variations of intracellular Ca2+concentration in T lymphocyte cell is proposed and *** cell is assumed to be a circular shaped geomnetrical domain for the representation of properties of Ca2+dynamics within the cell includ-ing important ***2+binding proteins for the dynamics of Ca2+are itself buffer and other physiological parameters located in Ca2+*** model incorpo-rates the important biophysical processes like difusion,reaction,voltage gated Ca2+channel,leak from endoplasmic reticulum(ER),efflux from cytosol to ER via sarco ER Ca2+adenosine triphosphate(SERCA)pumps,buffers and Na+/Ca2+*** proposed mathematical model is solved using a finite difference method and the finite element *** initial and boundary conditions are incorporated in the model based on biophysical conditions of the *** simulations in MAT-LAB R2019b are employed to investigate mathematical models of reaction-diffusion *** effect of source,buffer,Nat/Ca2+exchanger,*** spatial and tempo-ral patterns of Ca2+in T lymphocyte has been studied with the help of numerical *** the obtained results,it is observed that,the coordinated combination of the incor-porated parameters plays a significant role in Ca2+regulation in T *** leak and voltage-gated Ca2+channel provides the necessary Ca2+to the cell when required for its proper

关键词： Nat/Ca2+exchanger SERCA purmp ER leak voltage gated Ca2+channel buffers diffusion coefficient reaction-diffusion equations Ritz method and variational form

On the Application of pCA Technique to Fault Diagnosis

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Tsinghua Science and Technology 2010年第2期15卷 138-144页

作者： DING S ZHANG p DING E YIN S naik A DENG p GUI W Institute for Automatic Control and Complex Systems (AKS) University of Duisburg-Essen 47057 Duisburg Germany Department of physical Engineering University of Applied Sciences Gelsenkirchen 45877 Gelsenkirchen Germany School of Information Science and Engineering Central South University Changsha 410083 China

In this paper, we bdefly address the application of the standard principal component analysis （pCA） technique to fault detection and identification. Based on an analysis of the existing test statistic, we propose a new test statistic, which is similar to the Hawkin＇s T2 H statistic but without the numerical drawback. In comparison with the SpE index, the threshold setting associated with the new statistic is computationally simpler. Our further study is dedicated to the analysis of fault sensitivity. We consider the off-set and scaling faults, and evaluate the test statistic by viewing its sensitivity to the faults. Our final study focuses on identifying off-set and scaling faults. To this end, two algorithms are proposed. This paper also includes some critical remarks on the application of the pCA technique to fault diagnosis.

关键词： process monitoring fault diagnosis principal component analysis (pCA) multivariate analysis

Battery Charging Method for Electric Vehicles:From Wired to On-Road Wireless Charging

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Chinese Journal of Electrical Engineering 2018年第4期4卷 1-15页

作者： Kishore naik Mude Solace power Inc. 1118 Topsail road Mount PearlNewfoundland and LabradorA1N5E7Canada

Recent fossil fuel shortages and global warming related problems have caused a substantial shift from internal combustion engine vehicles towards *** paper explores the thorough review of battery charging infrastructure from wired connection to on-road wireless charging for an *** initial part of the paper deals with the wired charging and its power electronics *** later portion deals with the wireless charging where both static and On-Road types are ***,various aspects of wireless power transfer are also *** Market scenario and future growth prospects are reviewed and presented in last section of the paper.

关键词： Wired charging static WpT on-road WpT

Global dynamics of a fractional-order SIR epidemic model with memory

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International Journal of Biomathematics 2020年第8期13卷 1-23页

作者： parvaiz Ahmad naik School of Mathematics and Statistics Xi’an Jiaotong University Xi’an Shaanxi 710049P.R.China

In this paper,an investigation and analysis of a nonlinear fractional-order SIR epidemic model with Crowley-Martin type functional response and Holling type-II treatment rate are established along the *** existence and stability of the equilibrium points are *** sufficient conditions for the persistence of the disease are ***,a threshold value,Ro,is obtained which determines the stability of equilibria,then model equilibria are determined and their stability analysis is considered by using fractional Routh-Hurwitz stability criterion and fractional La-Salle invariant *** fractional derivative is taken in Caputo sense and the numerical solution of the model is obtained by LI scheme which involves the memory trace that can capture and integrate all past ***,by using Lyapunov functional approach,the global dynamics of the endemic equilibrium point is ***,some numerical simulations are performed to illustrate the effectiveness of the theoretical results *** outcome of the study reveals that the applied LI scheme is computationally very strong and effective to analyze fractional-order differential equations arising in disease *** results show that order of the fractional derivative has a significant effect on the dynamic ***,from the results,it is obvious that the memory effect is zero for p=*** the fractional-order p is decreased from 1,the memory trace nonlinearly increases from 0,and its dynamics strongly depends on *** memory effect points out the difference between the derivatives of the fractional-order and integer order.

关键词： SIR epidemic model Caputo fractional derivative LI scheme memory stability analysis reproduction number Ro

Suzaku observation of Be / X-ray binary pulsar EXO 2030+375

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Research in Astronomy and Astrophysics 2015年第4期15卷 537-548页

作者： Sachindra naik Gaurava K.Jaisawal Astronomy and Astrophysics Division Physical Research Laboratory

We study the timing and spectral properties of Be/X-ray binary pulsar EXO 2030＋375 using a Suzaku observation taken on 2012 May 23, during a less intense Type I outburst. pulsations were clearly detected in the X-ray light curves at a barycentric period of 41.2852 s, which suggest that the pulsar is spinning-up. The pulse profiles were found to be peculiar, e.g. unlike those obtained from the earlier Suzaku observation acquired on 2007 May 14. A single-peaked narrow profile at soft X-rays （0.5-10 keV range） changed to a double-peaked broad profile in the 12-55 keV energy range and again reverted back to a smooth single-peaked profile at hard X-rays （55-70 keV range）. The 1.0-100.0 keV broadband spectrum of the pulsar was found to be well described by three continuum models described as （i） a partial covering high energy cut-off power-law model, （ii） a partially absorbed power-law with high- energy exponential rolloff and （iii） a partial covering Negative and positive power law with EXponential （NpEX） continuum model. Unlike the earlier Suzaku observation during which several low energy emission lines were detected, a weak and narrow Iron Ka emission line at 6.4 keV was only present in the pulsar spectrum during the 2012 May outburst. Non-detection of any absorption like feature in the 1-100 keV energy range supports the claim of the absence of the cyclotron resonance scattering feature in EXO 2030＋375 from the earlier Suzaku observation. pulse-phase resolved spectroscopy revealed the presence of additional dense matter causing the absence of a second peak from the soft X-ray pulse profiles. The details of the results are described in the paper.

关键词： pulsars: individual (EXO 2030+375) -- stars: neutron -- X-rays: stars

Characterization of saline soil for the halophytes of largest inland saline wetland of India using geospatial technology

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Journal of Oceanology and Limnology 2023年第4期41卷 1277-1291页

作者： naik RAJASHREE Sharma LAXMI KANT Singh AVINASH Department of Environmental Science School of Earth SciencesCentral University of RajasthanBandarsindriAjmer 305817India

About 23%of the surface area and 44%of the volume of all the lakes are occupied by saline lakes in the ***,agricultural diversion,illegal encroachment,pollution,and invasive species could cause these lakes to dry up completely or partially by *** saltpan encroachment is causing Sambhar,India’s largest saline lake,to shrink by 4.23%every *** study aims to characterize the soil parameters where halophytes are growing.A literature survey was conducted for halophytes and soil *** study area was divided into four zones for stratified random *** sampling was conducted in February *** soil indicators for halophyte selected were pH,electrical conductivity,moisture,salinity,organic carbon,and organic *** obtained results were interpolated in the geospatial platform for soil characteristic *** is found that no research is conducted on halophytes of the *** on soil are also inconsistent and only six common parameters could be *** show that the pH ranged 9.37-7.66,electrical conductivity was 16.1-0.38,moisture 23.37%-1.2%,organic carbon 3.29%-0.15%,organic matter 5.6%-0.2%,and salinity 8.86%-0.72%.Though these results show improved condition as compared to last few years,in long term,the lake is *** the UN Decade of Ecosystem Restoration(2021-2030),if these causes are not addressed,the ecosystem may completely dry up.

关键词： halophytes inland lakes saline wetlands soil geospatial mapping interpolation

Advanced microemulsion synthesis and characterization of wollastonite （CaSiO3）fpolystyrene one-dimensional nanorods with core-shell structures

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particuology 2017年第1期15卷 118-128页

作者： Aniruddha Chatterjee prashant Khobragade, Satyendra Mishra Jitendra naik University Institute of Chemical Technology North Maharashtra University Jalgaon 425001 Maharashtra India

In this work, one-dimensional core-shell nanorods （CSNRs; 185-250nm wide and 1-1.5μm long） consisting of triethoxyvinylsilane-modified wollastonite （CaSiO3） nanorods （MWNRs） as a core and polystyrene as a shell with uniform size were successfully synthesized using an advanced microemulsion technique. The effect of varying the surfactant cetyltrimethylammonium bromide （producing CSNRSCTAB） or sodium dodecyl sulphate （producing CSNRSSDS） upon the size and morphology of the CSNRs was investigated by field-emission scanning electron microscopy （FE-SEM）. X-ray diffractometry and Fourier transform infrared spectrophotometer revealed the existence of a strong interaction between the MWNRs and polystyrene, which implies that the polymer chains were successfully grafted onto the surface of the MWNRs. The CSNRs were blended with polypropylene by melt processing, and the effect of the CSNRs upon the morphological properties of the polypropylene matrix was investigated by FE-SEM and atomic force microscopy. It was observed that the polystyrene chains that grafted onto the CaSiO3 nanorods interfered with the aggregation of CaSiO3 nanorods in the polypropylene matrix and thus improved the compatibility of the CaSiO3 nanorods with the polypropylene matrix. Furthermore, the compatibility of CaSiO3 nanorods with polypropylene of CSNRsDs/polypropylene was superior to that of CSNRCTAB/polypropylene.

关键词： Core-shell structures Atomized microemulsion One-dimensional nanorods

Variability in pod and seed traits of pongamia pinnata pierre ecotypes in North Karnataka, India

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Journal of Forestry Research 2016年第3期27卷 557-567页

作者： Vinod Kumar patil G.R.naik Department of Biotechnology Gulbarga University

An evaluation of 30 naturally available candidate-plus trees（CpTs） of pongamia pinnata was carried out to elucidate the genetic variability and relationship of pod and seed traits and progeny growth traits to select the best planting material with higher productivity. Significant variations were observed in pod and seed characteristics,oil content, and during the progeny trial studies. The highest values were found in 100-pod weight（410.4 gm）and 100-seed weight（195.92 gm） and the phenotypic and genotypic variance was found maximum in 100 pod weight（4364.71 and 4289.93） and 100 seed weight（813.8 and768.93）, respectively. Estimates of the phenotypic coefficient of variance were higher than the genotypic coefficient of variance for all the pod and seed traits and progeny growth traits, which depict the predominant role of the environment. Approximately 99 % of broad-sense heritability was revealed in oil content, followed by 100-pod weight（98.28 %）, and canopy growth（96.93 %）. pod thickness shows the highest genetic advance of 56.61 %,followed by pod width（53.43 %） and canopy growth（49.3 %）. pod and seed traits have proven a positive correlation between each other and with progeny growth traits,except a few negative values. Hierarchical clustering by Ward＇s minimum variance cluster analysis showed phylogeographical patterns of genetic diversity. K-means clustering revealed that trees from different geographical regions were grouped together in a cluster where as trees from the same geographical area are placed in a different cluster. Seven pongamia ecotypes（GRp-8, 9, 13, 14, 18,28, and 29） are found superior in traits, namely 100-pod weight, 100-seed weight, oil content, germination rate,plant height, canopy growth, and collar diameter. The traits100-pod weight and 100-seed weight are highly correlated with the progeny growth traits and even have higher heritability and genetic advantages.

关键词： Biodiesel Morphological diversity pod andseed traits pongamia pinnata progeny trial

Android malware category detection using a novel feature vector‑based machine learning model

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Cybersecurity 2023年第3期6卷 74-84页

作者： Hashida Haidros Rahima Manzil S.Manohar naik Department of Computer Science Central University of KeralaKasaragod 671316KeralaIndia

Malware attacks on the Android platform are rapidly increasing due to the high consumer adoption of Android *** technologies have motivated cyber-criminals to actively create and disseminate a wide range of malware on Android *** researchers have conducted numerous studies on the detection of Android malware,but the majority of the works are based on the detection of generic Android *** detection based on malware categories will provide more insights about the malicious patterns of the ***,this paper presents a detection solution for different Android malware categories,including adware,banking,SMS malware,and *** this paper,a novel Huffman encoding-based feature vector generation technique is *** experiments have proved that this novel approach significantly improves the efficiency of the detection *** method makes use of system call frequencies as features to extract malware’s dynamic behavior *** proposed model was evaluated using machine learning and deep learning *** results show that the proposed model with the Random Forest classifier outperforms some existing methodologies with a detection accuracy of 98.70%.

关键词： Android malware Dynamic analysis Malware category Huffman codin