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国际医学放射学杂志 2022年第2期 246-246页

作者： S.pistocchi D.Strambo B.Bartolini p.Maeder R.Meuli p.michel 朱能谨

摘要目的不同MR灌注软件对急性缺血性卒中（AIS）和大血管闭塞（LVO）病人进行血管内取栓（EVT）治疗的选择及预后的影响尚不清楚。本研究旨在比较2种商用MRI软

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On Some Elliptic problems in Unbounded Domains

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Chinese Annals of Mathematics,Series B 2018年第3期39卷 597-606页

作者： michel CHIpOT Dedicated to philippe G. Ciarlet on the occasion of his 80th birthda

The author presents a method allowing to obtain existence of a solution for some elliptic problems set in unbounded domains,and shows exponential rate of convergence of the approximate solution toward the solution.

关键词： Elliptic Exponential convergence Unbounded domains

A Cross-sectional Real-life Study of the prevalence,Severity,and Determinants of Metabolic Dysfunction-associated Fatty Liver Disease in Type 2 Diabetes patients

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Journal of Clinical and Translational Hepatology 2023年第6期11卷 1377-1386页

作者： Quentin Binet Audrey Loumaye michel p Hermans Nicolas Lanthier Service d’Hépato-Gastroentérologie Cliniques universitaires Saint-LucUCLouvainBrusselsBelgium Service d’Endocrinologie et Nutrition Cliniques universitaires Saint-LucUCLouvainBrusselsBelgium

Background and Aims:Most data on liver assessment in type 2 diabetes mellitus(T2DM)patients are from retrospective cohorts with selection *** aimed at appraising the feasibility,results,and benefits of an outpatient systematic noninvasive screening for metabolic dysfunction-associated fatty liver disease(MAFLD)severity and determinants in T2DM ***:We conducted a 50-week crosssectional study enrolling adult T2DM outpatients from a diabetes *** algorithm based on guidelines was applied using simple bioclinical scores and,if applicable,ultrasound and/or ***:Two hundred and thirteen patients were *** age and body mass index were 62 years and 31 kg/m^(2) and 29% of patients had abnormal transaminase *** acceptance rate of additional liver examinations was 92%.The prevalence of MAFLD,advanced fibrosis and cirrhosis was 87%,11%,and 4%,*** than half of the cases of advanced fibrosis had not been suspected and were detected by this *** was associated with poor glycemic control,elevated transaminases,low HDL-C and the absence of peripheral arterial *** fibrosis was linked to high waist circumference and excessive alcohol consumption,which should be interpreted with caution owing to the small number of patients reporting excessive ***:Simple bioclinical tools allowed routine triage of T2DM patients for MAFLD severity,with high adherence of high-risk patients to subsequent noninvasive exams.

关键词： Noninvasive tests MAFLD Outpatient Steatosis Fibrosis

Epididymitis： revelations at the convergence of clinical and basic sciences

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Asian Journal of Andrology 2015年第5期17卷 756-763,I0007页

作者： Vera michel Adrian pilatz Mark p Hedger Andreas Meinhardt Department of Anatomy and Cell Biology Department of Urology Pediatric Urology and Andrology Justus-Liebig-University of Giessen 35385 Giessen Germany Centre for Reproductive Health MIMR-PHI Institute of Medical Research Melbourne Victoria Australia

Acute epididymitis represents a common medical condition in the urological outpatient clinic. Mostly, epididymitis is caused by bacterial ascent through the urogenital tract, with pathogens originating either from sexually transmitted diseases or urinary tract infections. Although conservative antimicrobial therapy is possible in the majority of patients and is usually sufficient to eradicate the pathogen, studies have shown persistent oligozoospermia and azoospermia in up to 40% of these patients. Animal models of epididymitis are created to delineate the underlying reasons for this observation and the additional impairment of sperm function that is often associated with the disease. Accumulated data provide evidence of a differential expression of immune cells, immunoregulatory genes and pathogen-sensing molecules along the length of the epididymal duct. The evidence suggests that a tolerogenic environment exists in the caput epididymidis, but that inflammatory responses are most intense toward the cauda epididymidis. This is consistent with the need to provide protection for the neo-antigens of spermatozoa emerging from the testis, without compromising the ability to respond to ascending infections. However, severe inflammatory responses, particularly in the cauda, may lead to collateral damage to the structure and function of the epididymis. Convergence of the clinical observations with appropriate animal studies should lead to better understanding of the immunological environment throughout the epididymis, the parameters underlying susceptibility to epididymitis, and to therapeutic approaches that can mitigate epididymal damage and subsequent fertility problems.

关键词： acute epididymitis animal models of bacterial epididymitis epididymal duct epididymal immune environment fertility

Incidence and outcomes of intracerebral haemorrhage with mechanical compression hydrocephalus

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Stroke & Vascular Neurology 2021年第3期6卷 328-336页

作者： Bryce Owen Omar Akbik michel Torbey Herbert Davis Andrew p Carlson School of Medicine University of New Mexico School of MedicineAlbuquerqueNew MexicoUSA Neurosurgery University of New MexicoAlbuquerqueNew MexicoUSA Neurology University of New MexicoAlbuquerqueNew MexicoUSA Division of Epidemiology Biostatisticsand Preventive MedicineUniversity of New MexicoAlbuquerqueNew MexicoUSA

Introduction Intracerebral haemorrhage(ICH)within deep structures adjacent to the third ventricle is associated with worse outcomes when compared with lobar ICH due to the critical role of deep nuclei in normal neurological *** evidence suggests another contributing factor to poor outcome is obstruction of cerebrospinal fluid outflow by clot burden causing mechanical compression of the third *** authors reviewed the incidence and outcomes of mechanical compression ICH in order to identify this high-risk group which may potentially benefit from minimally invasive *** patients with spontaneous,non-traumatic,supratentorial ICH were identified retrospectively over a 30-month *** imaging was reviewed to assess location of the ICH,volume of the ICH,presence of hydrocephalus requiring external ventricular drain(EVD)placement,and time to clearing of the third *** was then categorised as due to‘primarily intraventricular haemorrhage(IVH)’,‘primarily mechanical compression’or‘mixed’.Functional outcomes at discharge were assessed using the modified Rankin Score(mRS).Results 287 patients met inclusion criteria,of which 39(13.5%)patients developed hydrocephalus that required *** patients had significantly higher mRS at discharge(p≤0.001)when compared with the non-EVD *** location was associated with lower odds of poor outcome compared with thalamic location(OR 0.107-0.560).Mechanical compression hydrocephalus was associated with poor outcome when compared with the primary IVH hydrocephalus subgroup(p=0.037)as well as longer time to clearing of the third ventricle(p=0.006).Conclusions Mechanical obstruction requiring EVD occurs in approximately(21/287)7.3%of all patients with spontaneous supratentorial *** is unknown if the worse morbidity in these subjects is purely related to damage to deep structures surrounding the third ventricle or if secondary damage from hydrocephalus could be mitigated with tar

关键词： hydrocephalus damage primarily

A new family of carbonaceous cathodes for rechargeable batteries through electronic structure tuning engineering

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National Science Review 2021年第2期8卷 7-8页

作者： michel Armand Centre for Cooperative Research on Alternative Energies Basque Research and Technology Alliance

Electric vehicles(EVs) and grid storage for renewable energies will require batteries in tens of millions of tons, and thus they need to be sustainable. EVs call also for batteries with higher energy density than currently available, and this value is intrinsically limited by the properties of the transition metal oxide(TMO) cathodes [1]. There are two possible strategies to overcome these limitations: i) increase the operating voltage in the >4.4 V range; and ii) attempt to use more than one electron per transition metal [2]. The first strategy faces problems of electrolyte stability limit and oxygen evolution, and thus safety hazards. The second is limited to vanadium and nickel, but using only1.3 electrons for the former,

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Complete Coulomb stress changes induced by the Ms7.6 earthquake in Lancang-Gengma, Yunnan and triggering of aftershocks by dynamic and static stress

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Science China Earth Sciences 2007年第11期50卷 1655-1662页

作者： michel BOUCHON Université Joseph Fourier F38041 Grenoble France

The spatiotemporal evolution patterns of complete Coulomb stress changes caused by 1988 Ms7.6 earthquake in Lancang-Gengma, Yunnan, are calculated and studied. And the triggering problems of Ms7.2 Gengma shock occurring 13 minutes after the main shock and of Ms5.0―6.9 aftershocks within 24 days after the main shock are discussed. The results show that the spatial distribution patterns of complete Coulomb stress changes of the Ms7.6 main shock are strongly asymmetric. The areas of positive dynamic and static Coulomb stress are both coincident well with the strong aftershocks' loca-tions. The Ms7.2 Gengma shock and most of strong aftershocks are subjected to the triggering effect of dynamic and static Coulomb stresses induced by the Ms7.6 Lancang earthquake.

关键词： complete Coulomb stress changes,dynamic and static stress triggering,earthquakes in Yunnan

New partial Geometric Difference Sets and partial Geometric Difference Families

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Acta Mathematica Sinica,English Series 2017年第5期33卷 591-606页

作者： Jerod michel School of Mathematical Sciences Zhejiang University Hangzhou 310027 P. R. China

Using Galois rings and Galois fields, we construct several infinite classes of partial geometric difference sets, and partial geometric difference families, with new parameters. Furthermore, these partial geometric difference sets(and partial geometric difference families) correspond to new infinite families of directed strongly regular graphs. We also discuss some of the links between partially balanced designs, 2-adesigns(which were recently coined by Cunsheng Ding in "Codes from Difference Sets"(2015)), and partial geometric designs, and make an investigation into when a 2-adesign is a partial geometric design.

关键词： partial geometric design cyclotomic class directed strongly regular graph partial geometric difference set partial geometric difference family

Conodont evolution and stratotype sign of carboniferous Tournaisian-Visean boundary in South China

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Science China Earth Sciences 2005年第12期48卷 2131-2141页

作者： michel Coen Louvian University of Belgium B-1348 Louvian-la-Neuve Belgium

A stratotype section, boundary point and conodont sign have been recommended for GSSp of the Tournaisian-Visean boundary, based on studies of sectional sedimentology, conodont facies and phylogeneses in South China. Two areas representing margin and inner of the Yangtzi plate and three sections of different facies were chosen, i.e. the Longdianshan sec-tion of the platform facies in Liuzhou of Guangxi, the Yudong section of the ramp facies in Shidian of Yunnan and the pengchong section of the basin facies in Liuzhou of Guangxi. Stratigraphic frameworks of two areas were set up by systematical studies of carbonate facies and cycles. Conodont facies-distribution and paleoecologic conditions were researched on statistics of fossil variation and richness, and a kind of planktonic conodont, gnathodids that were widespread, is chosen to select the sign-fossil from it. Seven conodont pedigrees were supplemented or erected by studies of statistics and transitional forms. Conodont evolution in the Early Carboniferous could be divided into three stages, i.e. the Siphonodella stage, the Gnathodus typicus stage and the Gnathodus bilineatus stage. The transform-surface between the later two stages could be put as the Tournaisian-Visean boundary. Finally, this paper proposes that the pengchong section can be the stratotype candidate of the Tournaisian-Visean boundary, the boundary point be put at the bottom of bed 58 and the stratotype sign of conodont be the first occurrence of Gnathodus praebilineatus of the Gnathodus semiglaber branch.

关键词： Tournaisian-Visean boundary, global stratotype, conodont evolution.

Which algebraic groups are picard varieties?

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Science China Mathematics 2015年第3期58卷 461-478页

作者： BRION michel Institut Fourier Universit'e de Grenoble

We show that every connected commutative algebraic group over an algebraically closed field of characteristic 0 is the picard variety of some projective variety having only finitely many non-normal *** contrast,no Witt group of dimension at least 3 over a perfect field of prime characteristic is isogenous to a picard variety obtained by this construction.

关键词： algebraic group picard variety pinching