检索结果-南通市图书馆

marine Life Science & Technology 2024年第2期6卷 266-279页

作者： Weiguang Kong Guangyi Ding Gaofeng cheng peng Yang Zhen Xu Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture Institute of HydrobiologyChinese Academy of SciencesWuhan 430072China Department of Aquatic Animal medicine College of FisheriesHuazhong Agricultural UniversityWuhan 430070China

The eye,as a specialized visual organ,is directly exposed to the external environment,and,therefore,it faces constant chal-lenges from external pathogenic organisms and *** the ocular mucosa(Om)of mammals,mucosal-associated lymphoid tissues(mALTs)constitute the primary line of ***,the immune defense role of the Om remains unknown in aquatic *** gain insights into the immune processes within the Om of teleost fish,we developed an infection model of rainbow trout(Oncorhynchus mykiss)Om using a parasite,Ichthyophthirius multifiliis(Ich).Immunofluorescence,qpCR,and H&E staining revealed that Ich successfully infiltrates the Om of rainbow trout,leading to pathological struc-tural changes,as evidenced by A&B ***,the qpCR results indicate an up-regulation of immune-related genes following Ich infection in the ***,transcriptome analyses were conducted to detect immune responses and impairments in eye function within the Om of rainbow trout with Ich *** results of the transcriptome analysis that Ich infection can cause an extensive immune response in the Om,ultimately affecting ocular *** the best of our knowledge,our findings represent for the first time that the teleost Om could act as an invasion site for parasites and trigger a strong mucosal immune response to parasitic infection.

关键词： Ocular mucosa mucosal immunity Transcriptome analysis Oncorhynchus mykiss Ichthyophthirius multifiliis

In situ thermoresponsive supramolecular assembly for switchable circularly polarized luminescence

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Chemistry 2024年第7期67卷 2362-2372页

作者： menghan pan Gong Zhang Haotian ma Xiaoxiao cheng Jieai Li Wei Zhang State and Local Joint Engineering Laboratory for Novel Functional polymeric materials Jiangsu Engineering Laboratory of Novel Functional Polymeric MaterialsSuzhou Key Laboratory of Macromolecular Design and Precision SynthesisCollege of ChemistryChemical Engineering and Materials ScienceSoochow UniversitySuzhou 215123China School of Chemical and Environmental Engineering Anhui Polytechnic UniversityWuhu 241000China

The dynamic regulation of circularly polarized luminescence(CpL)holds profound significance in various fields,such as highlevel information storage and *** we developed a chiral amphiphilic molecule,CpSB-GLU-pEG350(CGp),composed of aggregation-induced emission(AIE)chromophores(Z)-4-(1-cyano-2-phenylvinyl)benzoic acid(CpSB),a chiral linker Glutamic acid and polyethylene glycol(pEG)thermoresponsive *** the self-assembled supramolecular system formed by CGp,we have achieved in-situ temperature-responsive chiral structures,facilitating the thermal control switch of the CpL *** dynamics simulations demonstrate the distinct behaviors of AIE and pEG units during the temperature-variable assembly ***,by co-assembling achiral dye molecules with CGp,we have expanded the color range of the temperature-responsive CpL assembly system in situ and confirmed the occurrence of circularly polarizedF?rster resonance energy transfer(C-FRET)phenomenon in this process,which successfully enriched the strategies for in-situ CpL control in aqueous *** addition,the contactless radiative energy transfer of CpL can also be realized in this system,exhibiting more flexible temperature regulation of the CpL *** study provides a convenient and universal strategy for the construction of dynamically smart chiroptical materials.

关键词： circularly polarized luminescence in-situ thermoresponsive supramolecular assembly energy transfer

microstructure,wear and friction behavior of CoCrAITaY-xCNTs composite coatings deposited by laser-induction hybrid cladding

在线全文

学校读者我要写书评

暂无评论

Rare metals 2024年第4期43卷 1815-1827页

作者： Sheng-Feng Zhou Yu Long Yan-Liang Yi cheng Deng Lian-Xi Hu Institute of Advanced Wear&Corrosion Resistant and Functional materials Jinan UniversityGuangzhou510632China Wuhan National Laboratory for Optoelectronics(WNLO) Huazhong University of Science and TechnologyWuhan430074China mOE Key Laboratory of New processing Technology for Non-Ferrous metals and materials Guangxi Key Laboratory of Processing for Non-Ferrous Metals and Featured MaterialsGuangxi UniversityNanning530004China School of mechatronics Engineering Guangdong Polytechnic Normal UniversityGuangzhou510635China School of materials Science and Engineering Harbin Institute of TechnologyHarbin150001China

To improve the wear performance of CoCrAlYTa coating,part of the carbon nanotubes(CNTs)chemically reacted with Ta to form reinforcement phase(TaC),while the other CNTs were retained as lubrication ***,the CoCrAlYTa-xCNTs(x=0,1,2,and 4;wt%)composite coatings were prepared by laserinduction hybrid cladding(LIHC),and the microstructure and wear resistance of coatings were systematically *** show that the coatings are mainly composed of TaC,y-(Co,Cr)andβ-(Co,Cr)*** the CNTs content increases from 0 wt%to 4 wt%,the volume fraction of TaC increases from 13.11 vol%to 16.12 vol%.meanwhile,the nano-hardness ofγ-(Co,Cr)andβ-(Co,Cr)Al are improved from 7.49 and 9.72 to 9.36 and 11.19 Gpa,*** a result,the microhardness of coating increases from HV536.25 to HV 738.16,the wear rate decreases from32.4×10^(-3)to 6.1×10^(-3)mg·m^(-1),and the average friction coefficient decreases from 0.55 to *** good wear performance of the coating is attributed to the formation of TaC and the existence of remained CNTs lubricant film.

关键词： Carbon nanotube mCrAlY coating Friction and wear performance Laser-induction hybrid cladding

multimorbidity and mortality among older patients with coronary heart disease in Shenzhen,China

在线全文

学校读者我要写书评

暂无评论

Journal of Geriatric Cardiology 2024年第1期21卷 81-89页

作者： Fu-Rong LI Shuang WANG Xia LI Zhi-Yuan cheng cheng JIN Chun-Bao mO Jing ZHENG Feng-Chao LIANG Dong-Feng GU Shenzhen Key Laboratory of Cardiovascular Health and precision medicine Southern University of Science and TechnologyShenzhenGuangdongChina School of public Health and Emergency management Southern University of Science and TechnologyShenzhenGuangdongChina Shenzhen Health Development Research and Data management Center ShenzhenChina School of medicine Southern University of Science and TechnologyShenzhenGuangdongChina

BACKGROUND The current understanding of the magnitude and consequences of multimorbidity in Chinese older adults with coronary heart disease(CHD)is *** aimed to assess the association and population-attributable fractions(pAFs)between multimorbidity and mortality among hospitalized older patients who were diagnosed with CHD in Shenzhen,*** We conducted a retrospective cohort study of older Chinese patients(aged≥65 years)who were diagnosed with *** proportional hazards models were used to estimate the associations between multimorbidity and all-cause and cardiovascular disease(CVD)*** also calculated the *** The study comprised 76,455 older hospitalized patients who were diagnosed with CHD between January 1,2016,and August 31,*** them,70,217(91.9%)had multimorbidity,defined as the presence of at least one of the predefined 14 chronic *** with cancer,hemorrhagic stroke and chronic liver disease had the worst overall death risk,with adjusted HRs(95%CIs)of 4.05(3.77,4.38),2.22(1.94,2.53),and 1.85(1.63,2.11),*** CVD mortality,the highest risk was observed for hemorrhagic stroke,ischemic stroke,and chronic kidney disease;the corresponding adjusted HRs(95%CIs)were 3.24(2.77,3.79),1.91(1.79,2.04),and 1.81(1.64,1.99),***-cause mortality was mostly attributable to cancer,heart failure and ischemic stroke,with pAFs of 11.8,10.2,and 9.1,*** for CVD mortality,the leading pAFs were heart failure,ischemic stroke and diabetes;the corresponding pAFs were 18.0,15.7,and 6.1,*** multimorbidity was common and had a significant impact on mortality among older patients with CHD in Shenzhen,***,heart failure,ischemic stroke and diabetes are the primary contributors to ***,prioritizing improved treatment and management of these comorbidities is essential for the survival prognosis of CHD patients from a holistic public health perspective.

关键词： patients morbidity mortality

Genetic variation of circHIBADH enhances prostate cancer risk through regulating HNRNpA1-related RNA splicing

在线全文

学校读者我要写书评

暂无评论

Journal of Biomedical Research 2024年第4期38卷 358-368页

作者： Yifei cheng Rongjie Shi Shuai Ben Silu Chen Shuwei Li Junyi Xin meilin Wang Gong cheng Department of Environmental Genomics Jiangsu Key Laboratory of Cancer BiomarkersPrevention and TreatmentCollaborative Innovation Center for Cancer Personalized MedicineNanjing Medical UniversityNanjingJiangsu 211166China Department of Urology the First Affiliated Hospital of Nanjing Medical UniversityNanjingJiangsu 210029China Department of Bioinformatics School of Biomedical Engineering and InformaticsNanjing Medical UniversityNanjingJiangsu 211166China Jiangsu Cancer Hospital Jiangsu Institute of Cancer Researchthe Affiliated Cancer Hospital of Nanjing Medical UniversityNanjingJiangsu 210009China The Affiliated Suzhou Hospital of Nanjing medical University Suzhou Municipal HospitalGusu SchoolNanjing Medical UniversitySuzhouJiangsu 215002China

The current study aimed to investigate associations of circRNAs and related genetic variants with the risk of prostate cancer(pCa)as well as to elucidate biological mechanisms underlying the *** first compared expression levels of circRNAs between 25 paired pCa and adjacent normal tissues to identify riskassociated circRNAs by using the miOncoCirc *** then used logistic regression models to evaluate associations between genetic variants in candidate circRNAs and pCa risk among 4662 prostate cancer patients and 3114 healthy controls,and identified circHIBADH rs11973492 T>C as a significant risk-associated variant(odds ratio=1.20,95%confidence interval:1.08-1.34,p=7.06×10^(-4))in a dominant genetic model,which altered the secondary structure of the corresponding RNA *** the in silico analysis,we found that circHIBADH sponged and silenced 21 RNA-binding proteins(RBps)enriched in the RNA splicing pathway,among which HNRNpA1 was identified and validated as a hub RBp using an external RNA-sequencing data as well as the in-house(four tissue samples)and publicly available single-cell ***,we demonstrated that HNRNpA1 influenced hallmarks including mYC target,DNA repair,and E2F target signaling pathways,thereby promoting *** conclusion,genetic variants in circHIBADH may act as sponges and inhibitors of RNA splicing-associated RBps including HNRNpA1,playing an oncogenic role in pCa.

关键词： genetic variants prostate cancer circRNA RNA-binding protein RNA splicing sing-cell RNA sequencing

Introduction to the Special Issue on machine Learning-Guided Intelligent modeling with Its Industrial Applications

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computer modeling in Engineering & Sciences 2024年第10期141卷 7-11页

作者： Xiong Luo Yongqiang cheng Zhifang Liao School of Computer and Communication Engineering University of Science and Technology BeijingBeijing100083China Faculty of Technology University of SunderlandSunderlandSR60DDUK School of Computer Science and Engineering Central South UniversityChangsha410083China

With the advancement of Artificial Intelligence(AI)technology,traditional industrial systems are undergoing an intelligent transformation,bringing together advanced computing,communication and control technologies,machine Learning(mL)-based intelligentmodelling has become a newparadigm for solving problems in the industrial domain[1–3].With numerous applications and diverse data types in the industrial domain,algorithmic and data-driven mL techniques can intelligently learn potential correlations between complex data and make efficient decisions while reducing human ***,in real-world application scenarios,existing algorithms may have a variety of limitations,such as small data volumes,small detection targets,low efficiency,and algorithmic gaps in specific application domains[4].Therefore,many new algorithms and strategies have been proposed to address the challenges in industrial applications[5–8].

关键词： Intelligence bringing intelligent

Efficient piezo-assisted near-infrared-light-driven Cr（Ⅵ） reduction over Bi2S3 nanowires transformed from ultrathin Bi2WO6 nanosheets

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rare metals 2024年第9期43卷 4333-4343页

作者： Qiang Zhang Yuan-Hao cheng Wei Liu Hui-Nan Che Yan-Hui Ao Key Laboratory of Integrated Regulation and Resource Development On Shallow Lakes Ministry of Education College of Environment Hohai University

The utilization of piezo-photocatalytic technol ogy for environmental remediation under full spectrum solar light is promising but still ***,one dimensional Bi2S3nanowires,which can utilize both mechanical energy and near-infrared （NIR） light to remov hexavalent chromium (Cr （VI）) efficiently,were synthe sized by a restrained growth *** reaction rat constants of Cr （VI） reduction in piezo-photocatalyti process under NIR （800–2500 nm） reached 0.334 min-1which were 3.2 and 12.4 times as that of single piezo and photocatalytic *** formation of polarized electri fields and one-dimensional structure allow ultrafast sepa ration of charge carriers,thereby promoting the catalyti ***,due to the strong penetrability o NIR light,the piezo-photocatalysis performance in turbid solutions under NIR light (0.188 min-1) was even com parable to that under visible light (0.186 min-1).Thi study provides a new concept on the development of piezo photocatalytic technology for environmental remediation by utilization of NIR light and natural mechanical energy.

关键词： Bi2S3 nanowires Cr(VI) NIR light piezo-photocatalysis

A new method for evaluating wedges of steel plates and strips

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2024年第7期31卷 1719-1735页

作者： Xiao-bao ma Xiao-xin ma Tao Wang Zhong-kai Ren Yu-cheng Ren College of mechanical and Vehicle Engineering Taiyuan University of TechnologyTaiyuan 030024ShanxiChina ministry of Education Engineering Research Center of Advanced metal Composite Forming Technology and Equipment Taiyuan University of TechnologyTaiyuan 030024ShanxiChina National Key Laboratory of metal Forming Technology and Heavy Equipment Taiyuan University of TechnologyTaiyuan 030024ShanxiChina China National Heavy machinery Research Institute Co. Ltd.Xi'an 710018ShaanxiChina Faculty of mechanical Engineering Hebei University of ArchitectureZhangjiakou 075000HebeiChina

To overcome the inaccuracy problem of the traditional wedge evaluation of steel plates and strips caused by the ran-domness of the thicknesses of two local points and improve the reliability of the wedge index,the double-centroid method for the wedge evaluation was proposed,and a model based on the centroid theory was ***,an integral model for the discrete thickness values of the cross-section profiles was *** discussion focused on the distinct characteristics of the two-point method,asymmetric method,and double-centroid method in evaluating the asymmetric distribution of *** three methods were employed to evaluate the wedge values of both the theoretical and measured cross-sections of steel plates and strips,and the accuracies of three wedge evaluation models were analyzed and *** results showed that the double-centroid method objectively reflects the degree and variation characteristics of the wedge values of the cross-sections of steel plates and strips,and this method is feasible,reliable,and outstanding.

关键词： Steel plate and strip Wedge Two-point method Double-centroid method Reliability

Influences of shale microstructure on mechanical properties and bedding fractures distribution

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

petroleum Science 2024年第3期21卷 1944-1954页

作者： ming-Zhe Gu mao Sheng Shi-Zhong cheng Fan-Hao Gong Gen-Sheng Li State Key Laboratory of petroleum Resources and Engineering China University of Petroleum-BeijingBeijing2249China College of petroleum Engineering China University of Petroleum-BeijingBeijing102249China Shenyang Center of China Geological Survey ShenyangLiaoning110034China

The difference in microstructure leads to the diversity of shale mechanical properties and bedding fractures distribution *** this paper,the microstructure and mechanical properties of Longmaxi marine shale and Qingshankou continental shale were studied by X-ray diffractometer(XRD),field emission scanning electron microscope(FE-SEm)with mineral analysis system,and ***,the typical bedding layers area was properly stratified using Focused Ion Beam(FIB),and the effects of microstructure and mechanical properties on the distribution patterns of bedding fractures were *** results show that the Longmaxi marine shale sample contains more clay mineral grains,while the Qingshankou continental shale sample contains more hard brittle mineral grains such as *** Longmaxi marine shale sample,hard brittle minerals with grain sizes larger than 20μm is18.24%and those with grain sizes smaller than 20μm is 16.22%.For Qingshankou continental shale sample,hard brittle minerals with grain sizes larger than 20μm is 40.7%and those with grain sizes smaller than 20μm is 11.82%.In comparison to the Qingshankou continental shale sample,the Longmaxi marine shale sample has a lower modulus,hardness,and *** shales are formed by alternating coarse-grained and fine-grained layers during *** average single-layer thickness of Longmaxi marine shale sample is greater than Qingshankou continental shale *** two types of shale have similar bedding fractures distribution patterns and fractures tend to occur in the transition zone from coarse-grained to fine-grained *** orientation of the fracture is usually parallel to the bedding plane and detour occurs in the presence of hard brittle *** fracture distribution density of the Longmaxi marine shale sample is lower than that of the Qingshankou continental shale sample due to the strong heterogeneity of the Qingshankou continental *** current resea

关键词： Shale Nanoindentation microstructure mechanical property Fracture

Effect of slag composition on kinetic behavior of deep deoxidation of 5 wt.% Si high-silicon austenitic stainless steel

在线全文

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2024年第8期31卷 1873-1885页

作者： Guan-xiong Dou Han-jie Guo Jing Guo Xue-cheng peng Qing-yun Chen School of metallurgical and Ecological Engineering University of Science and Technology Beijing(USTB)Beijing 100083China Beijing Key Laboratory of Special melting and preparation of High-End metal materials Beijing 100083China

Based on a thermodynamic study of 5 wt.%Si high-silicon austenitic stainless steel(SS-5Si)smelting using CaF_(2)-CaO-Al_(2)0_(3)-mg-Si0_(2) slag to obtain a low oxygen content of less than 10×10^(-4) wt.%,a kinetic mass transfer model for deep deoxidation was established through laboratory studies,and the effects of slag components and temperature on deoxidation during the slag-steel reaction process of sS-5Si were systematically *** experimental data verified the accuracy of the model *** results showed that the final oxygen content in the steel at 1873 K was mainly controlled by the oxygen content derived from the activity of SiO_(2) regulated by the[Si]-[O]equilibrium reaction in the slag system;in particular,when the slag basicity R(R=w(CaO)/w(SiO2),where w(CaO)and w(SiO_(2))are the contents of CaO and SiO_(2) in the slag,respectively)is 3,the Al2O3 content in the slag needs to be less than 2.7%.The mass transfer rate equation for the kinetics of the deoxidation reaction revealed that the mass transfer of oxygen in the liquid metal is the rate-controlling step under different slag conditions at 1873 K,and the oxygen transfer coefficient ko.m increases with increasing the slag basicity from 4.0×10^(-6)m s^(-1)(R=1)to 4.3×10^(-5) m s^(-1)(R=3).ko.m values at R=2 and R=3 are almost the same,indicating that high slag basicity has little *** integral of the mass transfer rate equation for the deoxidation reaction of SS-5Si under different slag conditions is *** total oxygen content of the molten steel decreases with increasing basicity from an initial content of 22×10^(-4) to 3.2×10^(-4) wt.%(R=3),consistent with the change in ko.m with slag *** R=2,the slag-steel reaction takes 15 min to reach equilibrium(w[O]=5.5×10^(-4) wt.%),whereas at R=3,the slag-steel reaction takes 30 min to reach equilibrium(w[0]=3.2×10^(-4) wt.%).Considering the depth of deoxidation and reaction time of SS-5Si smelting,it is recommended the slag b

关键词： Slag-steel reaction Kinetics Rate-controlling step Deep deoxidation Transfer coefficient