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Development of metal organic fromwork-199 immobilized zeolite foam for adsorption of common indoor VOCs

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Journal of Environmental Sciences 2017年第5期29卷 321-330页

作者： Vipin k.saini Joao pires School of Environment and Natural Resources Doon UniversityDehradun 248001India Department of Chemistry and Biochemistry Faculty of SciencesUniversity of LisbonLisbon 1749-016Portugal

Reticulated foam shaped adsorbents are more efficient for the removal of volatile organic compounds（VOCs）,particularly from low VOC-concentration indoor air streams. In this study composite structure of zeolite and metal organic frameworks（MOFs）,referred as ZMF,has been fabricated by immobilization of fine MOF-199 powder on foam shaped Zeolite Socony Mobil-5（ZSM-5）Zeolitic structure,referred as ZF. The ZMF possess a uniform and well-dispersed coating of MOF-199 on the porous framework of ZF. It shows higher surface area,pore volume,and VOCs adsorption capacity,as compared to ***-fabrication changes in selective adsorption properties of ZMF were studied with three common indoor VOCs（benzene,n-hexane,and cyclohexane）,using gravimetric adsorption technique. The adsorption capacity of ZMF with different VOCs follow the order of benzene 〉 n-hexane 〉 cyclohexane. In comparison with MOF-199 and ZF,the composite structure ZMF shows improvement in selectivity for benzene from other two VOCs. Further,improvement in efficiency and stability of prepared ZMF was found to be associated with its high MOF loading capacity and unique morphological and structural properties. The developed composite structure with improved VOCs removal and recyclability could be a promising material for small to limited scale air pollution treatment units.

关键词： VOCs Adsorption Composite materials Selectivity Zeolite foam MOFs HkUST-1

Resolution Enhancement of Optical Surface plasmon Resonance Sensor Using Metamaterial

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photonic Sensors 2015年第4期5卷 330-338页

作者： Sarika pAL Y. k. pRAJApATI J. p. saini V. SINGH Sarika pal Department of Electronics & Communication Engineering KIET Ghaziabad (U.P.) India yogendra kumar prajapati Department of Electronics & Communication Engineering MNNIT Allahabad-211004 (U.P.) India jai prakash saini Department of Electronics & Communication Engineering BIET Jhansi-284128 (U.P.) India Vivek Singh Department of Physics Faculty of Science Banaras Hindu University Varanasi (U.P.) India

In this paper, we present and discuss a an optical surface plasmon resonance （SpR） path to extend the enhancement of the resolution of sensor. Basically, our approach is to combine bi-metamaterial layers to design the SpR sensor. The calculation shows that the proposed SpR sensor structure has a preference over the conventional SpR sensors and bimetallic SpR sensors since it gives a much sharper reflectance dip and can achieve considerable sensitivity improvement when compared to the recently reported investigations. The effects of the metamaterial permittivity, permeability, and thickness on the reflectance curve are studied. It is also seen that metamaterial layers improve the field of the proposed SpR structure, which may provide a novel tool to significantly enhance the sensitivity and resolution of the sensors.

关键词： Surface plasmon resonance sensor metamaterials Fresnel equations reflectance

Alteration in the expression of microRNA-21 regulated target genes:Role in breast cancer

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BIOCELL 2022年第2期46卷 309-324页

作者： pRIYANkA THAkUR REENA V.saini ANIL k.CHHILLAR NEERAJ k.saini VIJAY kUMAR THAkUR SAMARJEET SINGH SIWAL ADESH k.saini Faculty of Sciences Shoolini UniversitySolan173229India Department of Biotechnology MMECMaharishi Markandeshwar(Deemed to be University)Ambala133207India Maharishi Markandeshwar University Solan173229India Centre of Biotechnology Maharshi Dayanand UniversityRohtak124001India School of Biotechnology Jawaharlal Nehu UniversityNew Delhi110067India Biorefining and Advanced Materials Research Center Scotland’s Rural College(SRUC)EdinburghEH93JGUK Department of Chemistry MMECMaharishi Markandeshwar(Deemed to be University)Ambala133207India

Breast cancer,also recognized as the principal cause of cancer-related deaths among women,is the second most familiar and prevalent form of *** diagnostic and prognostic biomarkers that are highly specific are urgently needed for its early ***(miRNAs),a class of non-coding RNAs,are known to control the biological processes involving transcription,post-transcriptional and covalent modifications,splicing,translation,cell differentiation,proliferation,apoptosis,cancer progression,and *** dysregulation in miRNA expression,demonstrating their oncogenic and tumor-suppressive functions,contributes to cancer ***-21(miR-21),an‘onco-miR’in breast cancer,is involved in tumor progression and metastasis by suppressing the activity of the target gene via its interaction with the 3’UTR of the target *** upregulation of miR-21 is observed in many instances of breast *** review aims to summarize the current understanding of miR-21 in the regulation of important cellular functions via regulation of its target *** discuss its biosynthesis,oncogenic function in breast cancer,and different methods used for its *** will increase the current understanding of the role of miR-21 in breast cancer tumorigenesis,which will offer a perception of using miR-21 as an early detection molecular prognostic and diagnostic biomarker and as a therapeutic target in breast cancer care.

关键词： Non-coding RNA microRNAs Breast cancer Tumor suppression Biomarker

Approaches for Optimal planning of Energy Storage Units in Distribution Network and Their Impacts on System Resiliency

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CSEE Journal of power and Energy Systems 2020年第4期6卷 816-833页

作者： Balaji Venkateswaran V Devender k.saini Madhu Sharma Department of Electrical and Electronics Engineering University of Petroleum and Energy StudiesDehradun 248007India

In the recent decade,a significant increase in the penetration level of renewable energy sources(RESs)into the distribution grid is evident due to the world’s shift towards clean energy and to increase the reliability or inboard manner resiliency of electrical distribution *** based microgrids are the most favorable option available,especially to enhance ***,the integration of RES over the distribution grid would hamper the grid stability due to its stochastic nature under normal *** extreme weather conditions,RES behavior is completely *** there is a need to eliminate the adverse effects caused by the RES and make the distribution grid more reliable and stable under normal and resilient *** address these issues,many researchers proposed several methods to place energy storage units(ESUs)and microgrids(RES integrated),which can support critical loads at an optimal location in the distribution system during normal and extreme conditions,*** aim of this article is to consolidate and review the research towards various approaches to formulate the problem(optimal location,allocation,and operation of ESU and microgrids to face regular and extreme weather condition)and tools to solve it for enhanced system flexibility and *** on the review,a generalized methodology has been designed to adapt the inputs and address both *** the end of the review,future aspects for ESU to strengthen resistance and resiliency of its own are presented,which can be helpful to further improve the reliability and resiliency of the distribution system.

关键词： Energy storage units(ESUs) electrical distribution grid resiliency renewable energy sources(RES)

miR-153 as biomarker for cancer-functional role as tumor suppressor

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BIOCELL 2022年第1期46卷 13-26页

作者： SALONI THAkUR ADESH k.saini JOYDEEp DAS VIpIN saini pARIN BALHARA JAGpREET S.NANDA REENA V.saini Faculty of Applied Sciences and Biotechnology Shoolini UniversitySolan173229India Department of Biotechnology MMECMaharishi Markandeshwar(Deemed to be University)Mullana133207India Maharishi Markandeshwar University KumarhattiSolan173229India Department of Chemistry Physical SciencesMizoram UniversityAizawl796004India Department of kinesiology California State UniversitySacramentoCA 95819USA Laboratory on the Mechanism and Regulation of protein Synthesis Eunice K.ShriverNational Institute of Child Health and Human DevelopmentNational Institutes of HealthBethesdaMD 20892USA

MicroRNA-153(miR-153),belongs toa dass of small non-coding *** is a aritical regulator of gene expression at the post-transcriptional lewel which interacts with the functional mRNA at 3UTR rgion and suppresses the expression of the *** recently,it has become apparent that dhanges in the miR-153 axpression lead to invasion,metastasis,angiogenesis and various types of tumor *** review summarizes the connection between dysrgulation of miR-153 and various typas of cancer ***-153 regulates various signaling pathways to inhibit the proliferation and induce apoptosis in the ancer cell and also show synergistic activity with anticancer *** addition to this,the oncogenic bchavior of miR-153 and their use as a potential biomarker in cancer was also reviewed.

关键词： Biomarker Cancer miR-153 Oncogenic Tumor suppressor

Change profile analysis of open-source software systems to understand their evolutionary behavior

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Frontiers of Computer Science 2018年第6期12卷 1105-1124页

作者： Munish saini kuljit kaur CHAHAL Department of Computer Science Guru Nanak Dev UniversityAmritsar 143005India

Source code management systems (such as git) record changes to code repositories of Open-Source Software (OSS) projects. The metadata about a change includes a change message to record the intention of the change. Classification of changes, based on change messages, into different change types has been explored in the past to understand the evolution of software systems from the perspective of change size and change density only. However, software evolution analysis based on change classification with a focus on change evolution patterns is still an open research problem. This study examines change messages of 106 OSS projects, as recorded in the git repository, to explore their evolutionary patterns with respect to the types of changes performed over time. An automated keyword-based classifier technique is applied to the change messages to categorize the changes into various types (corrective, adaptive, perfective, preventive, and enhancement). Cluster analysis helps to uncover distinct change patterns that each change type follows. We identify three categories of 106 projects for each change type: high activity, moderate activity, and low activity. Evolutionary behavior is different for projects of different categories. The projects with high and moderate activity receive maximum changes during 76–81 months of the project lifetime. The project attributes such as the number of committers, number of files changed, and total number of commits seem to contribute the most to the change activity of the projects. The statistical findings show that the change activity of a project is related to the number of contributors, amount of work done, and total commits of the projects irrespective of the change type. Further, we explored languages and domains of projects to correlate change types with domains and languages of the projects. The statistical analysis indicates that there is no significant and strong relation of change types with domains and languages of the 106 proje

关键词： software evolution open-source software (OSS) cluster analysis change classification

SSA-HIAST: A Novel Framework for Code Clone Detection

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Computers, Materials & Continua 2022年第5期71卷 2999-3017页

作者： Neha saini Sukhdip Singh Deenbandhu Chhotu Ram University of Science and Technology Murthal131001India

In the recent era of software development,reusing software is one of the major activities that is widely used to save *** reuse software,the copy and paste method is used and this whole process is known as code *** activity leads to problems like difficulty in debugging,increase in time to debug and manage software *** the literature,various algorithms have been developed to find out the clones but it takes too much time as well as more space to figure out the ***,most of them are not *** problem has been targeted upon in this *** the proposed framework,authors have proposed a new method of identifying clones that takes lesser time to find out clones as compared with many popular code clone detection *** proposed framework has also addressed one of the key issues in code clone detection i.e.,detection of near-miss(Type-3)and semantic clones(Type-4)with significant accuracy of 95.52%and 92.80%*** present study is divided into two phases,the first method converts any code into an intermediate representation form i.e.,Hashinspired abstract syntax *** the second phase,these abstract syntax trees are passed to a novel approach“Similarity-based self-adjusting hash inspired abstract syntax tree”algorithm that helps in knowing the similarity level of *** proposed method has shown a lot of improvement over the existing code clones identification methods.

关键词： Code cloning clone detection hash inspired abstract syntax tree rotations hybrid framework

Surface ozone scenario and air quality in the north-central part of India

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Journal of Environmental Sciences 2017年第9期29卷 72-79页

作者： Renuka saini Ajay Taneja pradyumn Singh Department of Chemistry Dr.Bhim Rao Ambedkar UniversityAgra 282002India

Tropospheric pollutants including surface ozone（O3）, nitrogen dioxide（NO2）, carbon monoxide（CO） and meteorological parameters were measured at a traffic junction（78°2′ E and 27°11′ N） in Agra, India from January 2012 to December 2012. Temporal analysis of pollutants suggests that annual average mixing ratios of tropospheric pollutants were： O3— 22.97 ± 23.36 ppbV,NO2— 19.84 ± 16.71 ppb V and CO — 0.91 ± 0.86 ppm V, with seasonal variations of O3 having maximum mixing ratio during summer season（32.41 ± 19.31 ppbV）, whereas lowest was found in post-monsoon season（8.74 ± 3.8 ppbV）. O3 precursors： NO2 and CO, showed inverse relationship with O3. Seasonal variation and high O3 episodes during summer are associated with meteorological parameters such as high solar radiation, atmospheric temperature and transboundary transport. The interdependence of these variables showed a link between the daytime mixing ratios of O3 with the nighttime level of NO2. The mixing ratios of CO and NO2 showed tight correlations, which confirms the influence of vehicular emissions combined with other anthropogenic activities due to office/working hours, shallowing, and widening of boundary layer. FLEXTRA backward trajectories for the O3 episode days clearly indicate the transport from the NW and W to S/SE and SW direction at Agra in different seasons.

关键词： Surface ozone Ozone precursors Diurnal and seasonal variation pCA Ozone transport

Evaluation of CMIp6 for historical temperature and precipitation over the Tibetan plateau and its comparison with CMIp5

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Advances in Climate Change Research 2020年第3期11卷 239-251页

作者： ZHU Yu-Yao YANG saini State key Laboratory of Earth Surface processes and Resource Ecology Beijing Normal UniversityBeijing100875China key Laboratory of Environmental Change and Natural Disaster Ministry of EducationBeijing100875China Faculty of Geographical Science Academy of Disaster Reduction and Emergency ManagementBeijing Normal UniversityBeijing100875China

A model-by-model analysis for historical simulations was necessary for identifying reasonably performing models in the updated Coupled Model Intercomparison project(CMIp6)over the Tibetan *** determine whether the capacity of the CMIp6 models in simulating temperature and precipitation over the plateau has been enhanced,we compared the outputs of 23 CMIp6 models with an observational dataset(CN05.1)for the period 1961–*** results suggest the systematic model biases(cold bias and wet bias)in the Tibetan plateau still exist in *** models in CMIp6 realistically simulated the surface temperature and spatial distribution of precipitation,with a pattern correlation exceeding *** bias in the mean surface temperature of the multi-model ensemble(MME)simulation was 1.08℃ lower than the observational data,which had been decreased compared with the cold bias of CMIp5(1.52℃).At the seasonal scale,most models exhibited a warm temperature bias in summer and a cold bias in *** CMIp6 MME displayed a higher reproducibility of the precipitation amplitude over dry regions compared with CMIp5 and a lower ability over wet regions.

关键词： CMIp6 GCMs Temperature precipitation Tibetan plateau Climate change