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Moment Redistribution Effect of the Continuous Glass Fiber Reinforced polymer-Concrete Composite Slabs Based on Static Loading Experiment

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Structural durability & Health Monitoring 2025年第1期19卷 105-123页

作者： Zhao-jun Zhang Wen-Wei Wang jing-Shui Zhen Bo-Cheng Li De-Cheng Cai Yang-Yang du Hui Huang Offshore Oil Engineering Co.Ltd. Tianjin300461China Department of Bridge Engineering School of TransportationSoutheast UniversityNanjing211189China

This study aimed to investigate the moment redistribution in continuous glass fiber reinforced polymer(GFRp)-concrete composite slabs caused by concrete cracking and steel bar yielding in the negative bending moment *** experimental bending moment redistribution test was conducted on continuous GFRp-concrete composite slabs,and a calculation method based on the conjugate beam method was *** composite slabs were formed by combining GFRp profiles with a concrete layer and supported on steel beams to create two-span continuous composite slab *** methods,epoxy resin bonding,and stud connection,were used to connect the composite slabs with the steel *** experimental findings showed that the specimen connected with epoxy resin exhibited two moments redistribution phenomena during the loading process:concrete cracking and steel bar yielding at the internal *** contrast,the composite slab connected with steel beams by studs exhibited only one-moment redistribution phenomenon throughout the loading *** the concrete at the internal support cracked,the bending moment decreased in the internal support section and increased in the midspan *** the steel bars yielded,the bending moment further decreased in the internal support section and increased in the mid-span *** GFRp profiles do not experience cracking,there was no significant decrease in the bending moment of the mid-span *** test specimens experienced compressive failure of concrete at the mid-span *** results showed good agreement between the calculated and experimental values of bending moments in the mid-span section and internal support *** proposed model can effectively predict the moment redistribution behavior of continuous GFRp-concrete composite slabs.

关键词： Moment redistribution GFRp-concrete composite slabs bending moment experimental study analysis model

Small molecule inhibitor DDQ-treated hippocampal neuronal cells show improved neurite outgrowth and synaptic branching

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Neural Regeneration Research 2025年第9期20卷 2624-2632页

作者： jangampalli Adi pradeepkiran priyanka Rawat Arubala p.Reddy Erika Orlov pHemachandra Reddy Department of Internal Medicine Texas Tech University Health Sciences CenterLubbockTXUSA Department of Nutritional Sciences College of Human SciencesTexas Tech UniversityLubbockTXUSA Department of pharmacology&Neuroscience Texas Tech University Health Sciences CenterLubbockTXUSA Department of Neurology Texas Tech University Health Sciences CenterLubbockTXUSA Department of Speech Language and Hearing SciencesTexas Tech University Health Sciences CenterLubbockTXUSA Department of public Health Texas Tech University Health Sciences CenterLubbockTXUSA

The process of neurite outgrowth and branching is a crucial aspect of neuronal development and *** and dendrites,sometimes referred to as neurites,are extensions of a neuron's cellular body that are used to start *** we explored the effects of diethyl(3,4-dihydroxyphenethylamino)(quinolin-4-yl)methylphosphonate(DDQ)on neurite developmental features in HT22 neuronal *** this work,we examined the protective effects of DDQ on neuronal processes and synaptic outgrowth in differentiated HT22cells expressing mutant Tau(mTau)*** investigate DDQ chara cteristics,cell viability,biochemical,molecular,western blotting,and immunocytochemistry were *** outgrowth is evaluated through the segmentation and measurement of neural *** neural processes can be seen and measured with a fluorescence microscope by manually tracing and measuring the length of the neurite *** neuronal processes can be observed and quantified with a fluorescent microscope by manually tracing and measuring the length of the neuronal ***-treated mTau-HT22 cells(HT22 cells transfected with cDNA mutant Tau)were seen to display increased levels of synaptophysin,MAp-2,andβ-***,we confirmed and noted reduced levels of both total and p-Tau,as well as elevated levels of microtubule-associated protein 2,β-tubulin,synaptophysin,vesicular acetylcholine transporter,and the mitochondrial biogenesis protein-pe roxisome prolife rator-activated receptor-gamma coactivator-1α.In mTa u-expressed HT22 neurons,we observed DDQ enhanced the neurite characteristics and improved neurite development through increased synaptic *** findings conclude that mTa u-HT22(Alzheimer's disease)cells treated with DDQ have functional neurite developmental chara *** key finding is that,in mTa u-HT22 cells,DDQ preserves neuronal structure and may even enhance nerve development function with mTa u inhibition.

关键词： diethyl(3 4-dihydroxyphenethylamino)(quinolin-4-yl)methylphosphonate(DDQ) hippocampal neuronal cells HT22 neurite outgrowth neuronal development small molecule

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新生儿败血症的规范管理与挑战

中华儿科杂志 2025年第1期63卷 2-5页

作者：马晓路杜立中浙江大学医学院附属儿童医院新生儿监护中心杭州

新生儿败血症是导致新生儿死亡和严重并发症的重要原因, 早期诊断并及时治疗是改善预后的关键。应在风险预测、临床评估的基础上, 结合实验室检查结果进行新生儿败血症诊断, 避免过度抗生素治疗。规范化管理和质量改进项目有助于减少医...

新生儿败血症是导致新生儿死亡和严重并发症的重要原因, 早期诊断并及时治疗是改善预后的关键。应在风险预测、临床评估的基础上, 结合实验室检查结果进行新生儿败血症诊断, 避免过度抗生素治疗。规范化管理和质量改进项目有助于减少医院内获得性感染的发生。

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Experimental and Data Fitting Guidelines for the Determination of polymer Crystallization Kinetics

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Chinese journal of polymer Science 2022年第6期40卷 658-691页

作者： Ricardo Arpad perez-Camargo Guo-Ming Liu du-jin Wang Alejandro j.Muller Beijing National Laboratory for Molecular Sciences CAS Key Laboratory of Engineering PlasticsInstitute of ChemistryChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China pOLYMAT and Department of polymers and Advanced Materials:physics Chemistry and TechnologyFaculty of ChemistryUniversity of the Basque Country UPV/EHUDonostia-San Sebastián 20018Spain IKERBASQUE Basque Foundation for ScienceBilbao 48013Spain

The crystallization kinetics of semicrystalline polymers is often studied with isothermal experiments and analyzed by fitting the data with analytical expressions of the Avrami and Lauritzen and Hoffman(LH)*** correctly carry out the analysis,precautions in both experiments and data fitting should be ***,we systematically discussed the factors that influence the validity of the crystallization kinetics *** basic concepts and fundamentals of the Avrami and LH theories were introduced at ***,experimental protocols were discussed in *** clarify the impact of various experimental parameters,selected common polymers,i.e.,polypropylene and polylactide,were studied using various experimental techniques(i.e.,differential scanning calorimetry and polarized light optical microscopy).Common mistakes were simulated under conditions when non-ideal experimental parameters were ***,from a practical point of view,we show how to fit the experimental data to the Avrami and the LH theories,using an Origin■App developed by us.

关键词： Isothermal crystallization Avrami equation Lauritzen and Hoffman theory Thermal analysis Step-crystallization

Magnetic properties and magnetocaloric effects in(Ho_(1-x)Y_x)_5pd_2 compounds

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Chinese physics B 2019年第5期28卷 293-299页

作者： X F Wu C p Guo G Cheng C R Li j Wang Y S du G H Rao Z M du School of Materials Science and Engineering University of Science and Technology Beijing School of Materials Science and Engineering Guilin University of Electronic Technology Guangxi Key Laboratory of Information Materials

The crystal structure, magnetic and magnetocaloric properties of(Ho_(1-x) Y_(0.5))_5 pd_2 compounds are investigated. All the compounds crystallize in a cubic Dy_5 pd_2-type structure with the space group Fd3 m and undergo a second order transition from spin glass(SG) state to paramagnetic(pM) state. The spin glass transition temperatures T_g decrease from 26 K for x = 0 to 13 K for x = 0.5. In the pM region, the reciprocal susceptibilities for all the compounds obey the Curie–Weiss law. The paramagnetic Curie temperatures(θp) for Ho_5 pd_2,(Ho_(0.75) Y_(0.25)_5 pd_2, and(Ho_(0.5) Y_(0.5))_5 pd_2 are determined to be 32 K, 30 K, and 22 K, respectively, and the corresponding effective magnetic moments(μeff) are10.8 μB/Ho, 10.3 μB/RE, and 7.5 μB/RE, respectively. Magnetocaloric effect(MCE) is anticipated according to the Maxwell relation, based on the isothermal magnetization curves. For a magnetic field change of 0–5 T, the maximum values of the isothermal magnetic entropy change-?SMof the(Ho_(1-x)Y_x)_5 pd_2(x = 0, 0.25, and 0.5) compounds are determined to be 11.5 j·kg^(-1)·K^(-1), 11.1 j·kg^(-1)·K^(-1), and 8.9 K j·kg^(-1)·K^(-1), with corresponding refrigerant capacity values of 382.3 j·kg^(-1), 336.2 j·kg^(-1), and 242.5 j·kg^(-1), respectively.

关键词： (Ho1-xYx)5pd2 compounds magnetic transition magnetocaloric effect

Temporal dynamics of neonatal hypoxic-ischemic encephalopathy injuries on magnetic resonance imaging

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Neural Regeneration Research 2025年第11期20卷 3144-3150页

作者： Holly Flyger Samantha j.Holdsworth Alistair j.Gunn Laura Bennet Hamid Abbasi Mātai Medical Research Institute Tairāwhiti GisborneNew Zealand Department of Anatomy&Medical Imaging Faculty of Medical and Health SciencesThe University of AucklandAucklandNew Zealand Center for Brain Research The University of AucklandAucklandNew Zealand Auckland Bioengineering Institute The University of AucklandAucklandNew Zealand

Moderate to severe perinatal hypoxic-ischemic encephalopathy occurs in~1 to 3/1000 live births in high-income countries and is associated with a significant risk of death or neurodevelopmental *** assessment is important to help identify highrisk infants,to help families,and to support appropriate interventions.A wide range of monitoring tools is available to assess changes over time,including urine and blood biomarkers,neurological examination,and *** present,magnetic resonance imaging is unique as although it is expensive and not suited to monitoring the early evolution of hypoxic-ischemic encephalopathy by a week of life it can provide direct insight into the anatomical changes in the brain after hypoxic-ischemic encephalopathy and so offers strong prognostic information on the long-term outcome after hypoxic-ischemic *** review investigated the temporal dynamics of neonatal hypoxic-ischemic encephalopathy injuries,with a particular emphasis on exploring the correlation between the prognostic implications of magnetic resonance imaging scans in the first week of life and their relationship to long-term outcome prediction,particularly for infants treated with therapeutic hypothermia.A comprehensive literature search,from 2016 to 2024,identified 20 pertinent *** review highlights that while the optimal timing of magnetic resonance imaging scans is not clear,overall,it suggests that magnetic resonance imaging within the first week of life provides strong prognostic *** challenges limit the timing consistency,particularly the need for intensive care and clinical ***,although most reports examined the prognostic value of scans taken between 4 and 10 days after birth,there is evidence from small numbers of cases that,at times,brain injury may continue to evolve for weeks after *** suggests that in the future it will be important to explore a wider range of times after hypo

关键词： magnetic resonance imaging neonatal hypoxic-ischemic encephalopathy neurodevelopmental outcomes prognostic biomarkers in neuroimaging scan timing therapeutic hypothermia

Thoughts on strategies and paths to achieve carbon peaking and carbon neutrality in China

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Frontiers in Energy 2023年第3期17卷 324-331页

作者： Xiangwan du Chinese Academy of Engineering Beijing 100088China

First,a brief introduction is made to the four basic judgments and understandings of the goals of"carbon peaking and carbon neutrality."Then,an in-depth elaboration is provided on the eight major strategies for achieving the goals of"carbon peaking and carbon neutrality,"including conservation and efficiency priority,energy security,non-fossil energy substitution,reelectrification,resource recycling,carbon sequestration,digitalization and cooperation between ***,eight major implementation paths for achieving the goals of"carbon peaking and carbon neutrality"are discussed in detail,including industrial restructuring;building a clean,low-carbon,safe and_efficient energy system,and renewing the understanding of China's energy resource endowment;accelerating the construction of a new-type power system with a gradually growing proportion of new energy,and realizing the"possible triangle"of highquality energy system development;utilizing electrification and deep decarbonization technologies to promote the orderly peaking and gradual neutralization of carbon emissions in the industrial sector;promoting the lowcarbon transition of transportation vehicles to achieve carbon peaking and carbon neutrality in the transportation sector;focusing on breaking through key green building technologies to achieve zero carbon emissions from building electricity and heat;providing a strong technical support for carbon removal to achieve carbon neutrality;accelerating the construction of the integrated planning and assessment mechanism for pollution and carbon reduction,establishing a sound strategy,planning,policy and action system,and optimizing the carbon trading ***,it is particularly pointed out that the realization of the goals of"carbon peaking and carbon neutrality"cannot be separated from the support of scitech ***,it is stressed that carbon neutrality is not the end,but an important *** viewed from the perspective of future energy,

关键词： carbon peaking and carbon neutrality strategy implementation path important sci-tech innovation implementation path

A hidden precipitation scenario of theθ’-phase in Al-Cu alloys

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journal of Materials Science & Technology 2021年第16期75卷 126-138页

作者： L.Zhou C.L.Wu p.Xie F.j.Niu W.Q.Ming K.du j.H.Chen center for high-resolution electron microscopy college of materials science and engineeringhunan universitychangshahunan410082china shenyang national laboratory for materials science institute of metal researchchinese academy of sciences.shenyan7.110016china

Al-Cu binary alloys are important and interesting industry *** to date,the formation mechanisms of the key strengthening precipitates,namedθ’-phase,in the alloys are still ***,we report that for non-deformed bulk Al-Cu alloys theθ’-phase actually has its own direct precursors that can form only at elevated aging temperature(>ca.200℃).These high-temperature precursors have the same plate-like morphology as theθ’-phase precipitates but rather different *** imaging reveals that they have a tetragonal structure with a=0.405 nm and c=1.213 nm,and an average composition of Al_(5-x)Cu_(1+x)(0≤xprecursor phase may initiate with a composition of Al5 Cu and evolve locally towards Al_(4)Cu_(2)in composition,eventually leading to a consequent structural transformation into theθ’-phase(Al4 Cu2=Al2 Cu).There are evidences that because of their genetic links in structure,such a high-temperature precursor may transform to theθ’-phase without having to change their morphology and interface *** study reveals a well-defined and previously hidden precipitation scenario for theθ’-phase to form in Al-Cu alloys at an elevated aging temperature.

关键词： AlCu alloy Age-hardening precipitation Electron microscopy

Time Scale of partial Melting of KLB-1 peridotite: Constrained from Experimental Observation and Thermodynamic Models

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journal of Earth Science 2018年第2期29卷 245-254页

作者： Wei du Li Li Donald j.Weidner State Key Laboratory of Ore Deposit Geochemistry Institute of Geochemistry Chinese Academy of Sciences Mineral physics Institute Department of Geosciences University of New York at Stony Brook

partial melting experiments were carried on KLB-1 peridotite, a xenolith sample from the Earth＇s upper mantle, at 1.5 Gpa and temperatures from 1 300 to 1 600 ℃, with heating time varies from 1 to 30 min. We quantify the axial temperature gradient in the deformation-DIA appa- ratus （D-DIA） and constrain the time scale of partial melting by comparing experimental observa- tions with calculated result from pMELTS program. The compositions of the liquid phase and the coexisting solid phases （clinopyroxene, orthopyroxene, and olivine） agree well with those calculated from pMELTS program, suggesting that local chemical equilibrium achieves during partial melting, although longer heating time is required to homogenize the bulk sample. The Mg# （=Mg/（Mg＋Fe） moi.%） of olivines from the 1-minute heating experiment changed continuously along the axial of the graphite capsule. A thermal gradient of 50 ℃/mm was calculated by comparing the Mg# of oli- vine grains with the output of pMELTS program. Olivine grains at the hot end of the graphite cap- sule from the three experiments heated at 1 400 ℃ but with different annealing time show consis- tence on Mg#, indicating that partitioning of Fe2＋ between the olivine grains and the silicate melt happened fast, and partial melting occurs in seconds.

关键词： peridotite partial melting temperature gradient pMELTS program.