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Characterization of surface liquid segregation in SSM-HpDC aluminium alloys 7075,2024,6082 and A201

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中国有色金属学会会刊：英文版 2010年第S3期20卷 847-851页

作者： H.MLLER U.A.CURLE E.p.MASUKU Materials Science and Manufacturing Council for Scientific and Industrial Research(CSIR)PretoriaSouth Africa

The surface liquid segregation(SLS) phenomenon in semi-solid metal-high pressure die casting(SSM-HpDC) plates of 7075,2024,6082 and A201 was investigated by different *** profiles were determined by firstly measuring the chemical composition of the surface of the plates using a Thermo Quantris optical emission spectrometer(OES).Material was then removed by a grinding process followed by measurement of the amount of material removed and chemical *** profiles of the main alloying elements were plotted for the cross-section of the plates in the as-cast and T6(after solution treatment) temper *** hardness profiles from the surface to the centre of the plates were *** samples of cross-sections of the castings were prepared and evaluated using a scanning electron *** results show that surface liquid segregation in SSM-HpDC alloys causes significant differences in properties between the surface and the bulk of these castings in both the F and T6 temper conditions.

关键词： semi-solid metal(SSM) forming alloy 7075 alloy 2024 alloy 6082 alloy A201 surface liquid segregation

Telaprevir/boceprevir era: From bench to bed and back

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World Journal of gastroenterology 2012年第43期18卷 6183-6188页

作者： Maikel p peppelenbosch Harry LA Janssen Robert J de Knegt Department of gastroenterology and Hepatology Erasmus MC-University Medical Center 3015 CE Rotterdam The Netherlands

Hepatitis C virus (HCV) infects approximately 200 million people worldwide. Interferon-based therapies have dominated over the past two decades. However, the overall response rates remain suboptimal. Thanks to the tremendous effort from both academia and industry, two serine protease inhibitors telaprevir and boceprevir for treating chronic hepatitis C have finally reached the clinic. Although these compounds are only approved for combination use with interferon and ribavirin in genotype 1 HCV infected chronic patients, the management of HCV patients however is now evolving incredibly. Here, we overviewed a series of landmark studies, regarding the clinical development of telaprevir and boceprevir. We discussed the mechanism-of-action of telaprevir/boceprevir and their potential application in HCV-positive liver transplantation patients. We further emphasized some emerging concerns with perspective of further development in this field.

关键词： Telaprevir Boceprevir Mechanism-of-action Clinical efficacy Liver transplantation patient Interferon Ribavirin

gABA UpTAKE BY gAT1 MODULATES LONg-TERM OpTICAL CHANgES FOLLOWINg ELECTRICAL STIMULATION OF THE pITUITARY gLAND NEUROINTERMEDIATE LOBE

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Journal of Innovative Optical Health Sciences 2013年第3期6卷 46-57页

作者： p.KOSTERIN A.L.OBAID B.M.SALZBERg Department of Neuroscience perelman School of Medicine University of pennsylvania philadelphia PA 19104 Department of physiology perelman School of Medicine University of pennsylvania philadelphia PA 19104

Intrinsic optical changes that follow infundibular stalk stimulation of the neurointermediate lobe of the mouse pituitary gland exhibit three different phases that reflect three distinct physiological *** first(E-wave)is the rapid light-scattering increase that is associated with a nerve terminal volume increase(mechanical spike),and that accompanies excitation of the neurohy-pophysial terminals by the invading action potential;the second(S-wave)is the slower light-scattering decrease that is tightly corelated with the secretion of the peptide hormones oxytocin and arginine vasopressin,and the third is the long duration response(R-wave)that reflects cell volume changes in the pars *** have studied the E-wave and the S-wave in earlier *** R-wave,considered here,is sensitive to chloride replacement as wel as to blockade of chloride *** blocking gABAA reeptors(which are ligand gated chloride channels)with pharrmacological agents,and by applying gABA directly into the bathing solution,or evoking its release from gABAergic inputs,we have demonstrated that this long-duration optical response is sensitive to chloride movements and reflects gABA-induced changes in the intrinsic optical propertis of the pars *** full time course of this optical response takes mimutes and,therefore,has to embody some other process(or processes)related to the restoration of resting physiological chloride concentrations,following the opening and closing of gABA A-reeptor *** we demonstrate that the shape of the R wave,the longlasting light-scattering signal,is indeed affected by the activity of gAT1,one of the *** gA BA transporters.

关键词： Light scattering posterior pituitary pars nervosa neurohypophysis volume changes pars intermedic gABAA receptors

Entrance Effects in Microchannel gas Flow

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Journal of Thermal Science 2009年第4期18卷 345-352页

作者： T.Lewandowski S.Jebauer J.Czerwinska p.Doerffer Institute of Fluid Flow Machinery Polish Academy of Science Institute of Fundamental Technological Research Polish Academy of Science

Motivation of this work has its origin in the boundary layer control for aeronautics and turbomachinery. For thatpurpose boundary layer can be modified by perforated plates with holes of specific sizes. The questions whichrise in such configuration are related to the existence of optimal size of the holes and the influence of microscalephenomena on the global flow patterns. This paper concentrates on the issue of the entrance effects on the microchannelflow. It is shown that mass flow rate is only insignificantly influenced by slip effects. global parameterssuch as pressure difference and geometrical shape in more pronounced way alter flow behavior. In this paper weconcentrate on the numerical investigation of the microchannel flow for Kn gth is finite. Hence, entrance and outlet effects on microchannel flow can be studied.

关键词： perforated plates microchanneis gas flow simulations

Enhancing Internet of Things Intrusion Detection Using Artificial Intelligence

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Computers, Materials & Continua 2024年第10期81卷 1-23页

作者： Shachar Bar p.W.C.prasad Md Shohel Sayeed School of Computing MathematicsCharles Sturt UniversityBathurstNSW 2795Australia International School Duy Tan UniversityDa Nang550000Vietnam Faculty of Information Science and Technology Multimedia UniversityMelaka75450Malaysia

Escalating cyber security threats and the increased use of Internet of Things(IoT)devices require utilisation of the latest technologies available to supply adequate *** aim of Intrusion Detection Systems(IDS)is to prevent malicious attacks that corrupt operations and interrupt data flow,which might have significant impact on critical industries and *** research examines existing IDS,based on Artificial Intelligence(AI)for IoT devices,methods,and *** contribution of this study consists of identification of the most effective IDS systems in terms of accuracy,precision,recall and F1-score;this research also considers training *** demonstrate that graph Neural Networks(gNN)have several benefits over other traditional AI frameworks through their ability to achieve in excess of 99%accuracy in a relatively short training time,while also capable of learning from network traffic the inherent characteristics of different *** findings identify the gNN(a Deep Learning AI method)as the most efficient IDS *** novelty of this research lies also in the linking between high yielding AI-based IDS algorithms and the AI-based learning approach for data privacy *** research recommends Federated Learning(FL)as the AI training model,which increases data privacy protection and reduces network data flow,resulting in a more secure and efficient IDS solution.

关键词： Anomaly detection artificial intelligence cyber security data privacy deep learning federated learning industrial internet of things internet of things intrusion detection system machine learning

Radiopaque nano and polymeric materials for atherosclerosis imaging, embolization and other catheterization procedures

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Acta pharmaceutica Sinica B 2018年第3期8卷 360-370页

作者： Li Tian Linfeng Lu James Feng Marites p.Melancon Department of Interventional Radiology The University of Texas MD Anderson Cancer Center Duke University graduate School of Biomedical Sciences University of Texas Health Science Center at Houston

A review of radiopaque nano and polymeric materials for atherosclerosis imaging and catheterization procedures is presented in this paper. Cardiovascular diseases(CVDs) are the leading cause of death in the US with atherosclerosis as a significant contributor for mortality and morbidity. In this review paper, we discussed the physics of radiopacity and X-ray/CT, clinically used contrast agents,and the recent progress in the development of radiopaque imaging agents and devices for the diagnosis and treatment of CVDs. We focused on radiopaque imaging agents for atherosclerosis, radiopaque embolic agents and drug eluting beads, and other radiopaque medical devices related to catheterization procedures to treat CVDs. Common strategies of introducing radiopacity in the polymers, together with examples of their applications in imaging and medical devices, are also presented.

关键词： Radiopaque contrast nanoparticles and materials X-ray CT Vascular diseases Atherosclerosis plaque Stenosis Embolization Inferior vena cava filters

An Interacting gauge Field Theoretic Model for Hodge Theory: Basic Canonical Brackets

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Communications in Theoretical physics 2014年第6期61卷 715-728页

作者： R.Kumar S.gupta R.p.Malik Department of physics Centre of Advanced Studies Banaras Hindu University DST Centre for Interdisciplinary Mathematical Sciences Faculty of Science Banaras Hindu University

We derive the basic canonical brackets amongst the creation and annihilation operators for a two(1 + 1)-dimensional(2D) gauge field theoretic model of an interacting Hodge theory where a U(1) gauge field(Aμ) is coupled with the fermionic Dirac fields(ψ andˉψ). In this derivation, we exploit the spin-statistics theorem, normal ordering and the strength of the underlying six infinitesimal continuous symmetries(and the concept of their generators) that are present in the theory. We do not use the definition of the canonical conjugate momenta(corresponding to the basic fields of the theory) anywhere in our whole discussion. Thus, we conjecture that our present approach provides an alternative to the canonical method of quantization for a class of gauge field theories that are physical examples of Hodge theory where the continuous symmetries(and corresponding generators) provide the physical realizations of the de Rham cohomological operators of differential geometry at the algebraic level.

关键词： continuous symmetries 2D QED with fermionic Dirac fields symmetry principles basic canoni-cal (anti)commutators creation and annihilation operators conserved charges as generators deRham cohomological operators Hodge theory

Interactions of ion acoustic multi-soliton and rogue wave with Bohm quantum potential in degenerate plasma

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Chinese physics B 2017年第9期26卷 301-309页

作者： M S Alam M g Hafez M R Talukder M Hossain Ali Department of Applied Mathematics University of RajshahiRajshahi-6205Bangladesh plasma Science and Technology Lab Department of Applied Physics and Electronic EngineeringUniversity of RajshahiRajshahi-6205Bangladesh Department of Mathematics Chittagong University of Engineering and TechnologyChittagong-4349Bangladesh

This work investigates the interactions among solitons and their consequences in the production of rogue waves in an unmagnetized plasmas composing non-relativistic as well as relativistic degenerate electrons and positrons, and inertial non-relativistic helium ions. The extended poincare′–Lighthill–Kuo（pLK） method is employed to derive the two-sided Korteweg–de Vries（KdV） equations with their corresponding phase shifts. The nonlinear Schrodinger equation（NLSE） is obtained from the modified Kd V（mKdV） equation, which allows one to study the properties of the rogue waves. It is found that the Fermi temperature and quantum mechanical effects become pronounced due to the quantum diffraction of electrons and positrons in the plasmas. The densities and temperatures of the helium ions, degenerate electrons and positrons, and quantum parameters strongly modify the electrostatic ion acoustic resonances and their corresponding phase shifts due to the interactions among solitons and produce rogue waves in the plasma.

关键词： wave-wave interaction rogue waves degenerate plasmas Bohm potential

An explanation of the △_(D35)（1930） as a ρ△ bound state

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Chinese physics C 2009年第12期33卷 1267-1272页

作者： p. gonzlez E. Oset J. Vijande Departamento de Física Teórica Universidad de Valencia (UV) e IFIC (UV - CSIC) Spain Departamento de Física Atómica Molecular y Nuclear Universidad de Valencia (UV) e IFIC (UV - CSIC) Spain

Constituent quark models based on two-body potentials systematically overpredict the mass of △D35(1930). A possible solution to this problem comes out from the application of a schematic hybrid model, containing three-quark as well as meson-baryon components, to the light-quark baryon spectrum. The △D35(1930) and its partners △D33(1940) and △S31(1900) are found to contain a significant ρ△ component. Then, through the use of the hidden gauge formalism, it is shown that these resonances can be dynamically generated from the ρ-△ interaction. In particular △D35(1930) can be interpreted as being essentially a ρ△bound state. This interpretation suggests that the inclusion of ρ△as an effective inelastic channel in data analyses could improve the extraction and identification of the resonance.

关键词： Baryon spectra dynamically generated resonances quark model