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石油化工 2004年第3期33卷 202-205页

作者：贾美林 P.Afanasiev M.Vrinat 李文钊徐恒泳葛庆杰中国科学院大连化学物理研究所辽宁大连116023 Institute de Recherches sur la Catalyse

采用连续流动微反装置,考察了催化剂载体、载体焙烧温度、催化剂制备方法及催化剂中Ni/Mo配比对NiMo催化剂催化噻吩加氢脱硫反应性能的影响,并用BET,XRD和TpR对催化剂进行了表征。结果表明,催化剂载体影响催化剂的性能,对于无Ni助剂的... 详细信息

采用连续流动微反装置,考察了催化剂载体、载体焙烧温度、催化剂制备方法及催化剂中Ni/Mo配比对NiMo催化剂催化噻吩加氢脱硫反应性能的影响,并用BET,XRD和TpR对催化剂进行了表征。结果表明,催化剂载体影响催化剂的性能,对于无Ni助剂的催化剂,负载在TiO2载体上的Mo催化剂活性高于负载在ZrO2上的催化剂,而助剂Ni的添加改变了活性顺序,使负载在TiO2载体上的NiMo催化剂活性低于负载在ZrO2上的催化剂;催化剂制备方法影响催化剂的性能,以共浸法制备的催化剂表现出高的催化活性;Ni/Mo配比影响催化剂的性能,当Ni/Mo摩尔比为0 6时,催化剂具有最高活性。

关键词： NiMo催化剂二氧化锆二氧化钛噻吩加氢脱硫

Automatic Identification Fingerprint Based on Machine Learning Method

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Journal of the Operations Research Society of China 2022年第4期10卷 849-860页

作者： Long The Nguyen Huong Thu Nguyen Alexander Diomidovich afanasiev Tao Van Nguyen Laboratory of Artificial Intelligence and Machine Learning Institute of Information Technology and Data ScienceIrkutsk National Research Technical UniversityIrkutskRussia Baikal School of BRICS Irkutsk National Research Technical UniversityIrkutskRussia University of Information and Communication Technology Thai Nguyen UniversityThai NguyenViet Nam

The fingerprint identification technology has been developed and applied effectively to security systems in financial transactions,personal information security,national security,and other fields.In this paper,we proposed the development of a fingerprint identification system based on image processing methods that clarify fingerprint contours,using machine learning methods to increase processing speed and increase the accuracy of the fingerprint identification process.The identification system consists of the following main steps:improving image quality and image segmentation to identify the fingerprint area,extracting features,and matching the database.The accuracy of the system reached 97.75%on the mixed high-and low-quality fingerprint database.

关键词： Fingerprint identification Feature extraction Image segmentation Wavelet transform Neural network algorithm Machine learning

Relationship between mitochondrial respiratory dysfunction of blood mononuclear cells and heart failure severity

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Journal of Geriatric Cardiology 2024年第1期21卷 130-134页

作者： Viacheslav A.Korepanov Tariel A.Atabekov Tatiana Yu.Rebrova Roman E.Batalov Sergey A.afanasiev Cardiology Research Institute Tomsk National Research Medical CenterRussian Academy of SciencesTomskRussia

Chronic heart failure(CHF)is a clinical syndrome manifested by reduced pumping ability of the heart,increased pressure in heart chambers in both physical activity and at rest.The symptoms of this syndrome are dyspnea,undue fatigability,peripheral edema,which follow structural and functional changes of the myocardium.[1]The growing incidence of CHF,especially among elderly people,is an urgent problem for medicine in the vast majority of industrialized countries.For instance,in Russian Federation,CHF is diagnosed in about 7%of cardiovascular patients.At the same time,this indicator varies from 0.3%in young people(20-29 years old)to 70%in the older age group.[2,3].

关键词： severity instance pumping

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NiMo/ZrO_2加氢脱硫催化剂的研究

石油化工 2005年第3期34卷 218-221页

作者：贾美林 p A fanasiev M Vrinat 李文钊徐恒泳葛庆杰中国科学院大连化学物理研究所 Institute de Recherches sur la Catalyse 2 Avenue EinsteinVilleurbanne Cedex 69626France

采用共浸法制备了未经焙烧直接硫化的NiMo/ZrO2(550)、NiMo/ZrO2(650)催化剂及550℃焙烧后再硫化的NiMo/ZrO2(550)-1催化剂,在连续流动微反装置上考察了NiMo/ZrO2系列催化剂对噻吩加氢脱硫反应的催化活性,并对催化剂进行了X射线光电子能... 详细信息

采用共浸法制备了未经焙烧直接硫化的NiMo/ZrO2(550)、NiMo/ZrO2(650)催化剂及550℃焙烧后再硫化的NiMo/ZrO2(550)-1催化剂,在连续流动微反装置上考察了NiMo/ZrO2系列催化剂对噻吩加氢脱硫反应的催化活性,并对催化剂进行了X射线光电子能谱(XpS)和Raman光谱表征。表征结果显示,以四方相ZrO2为载体的NiMo/ZrO2(650)催化剂,由于被硫化的更完全,催化活性高于以无定形相ZrO2为载体的NiMo/ZrO2(550)催化剂,说明载体的结构影响催化剂的催化活性;550℃焙烧后的NiMo/ZrO2(550)-1催化剂的催化活性低于未经焙烧直接硫化的NiMo/ZrO2(550)催化剂,这是由于高温焙烧增加了活性组分和载体之间的相互作用,降低了催化剂的硫化程度,进而降低了其催化活性,说明这种强相互作用不利于提高催化剂的催化活性。

关键词：加氢脱硫催化剂 X射线光电子能谱(XpS) 催化活性直接硫化 ZrO2 Raman 强相互作用脱硫反应连续流动光谱表征结构影响活性组分高温焙烧硫化程度载体再硫化四方相无定形

Amiodarone Modulation of Intracellular Transport of Calcium Ions in Cardiomyocites

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pharmacology & pharmacy 2012年第3期3卷 307-315页

作者： Dina Kondratyeva Sergey afanasiev Sergey popov Roman Batalov Federal State Budgetary Institution Research Institute for Сardiology of Siberian Branch under the Russian Academy of Medical Sciences Tomsk Russia Federal State Budgetary Institution Research Institute for Сardiology of Siberian Branch under the Russian Academy of Medical Sciences Tomsk Russia.

The influence of amiodarone on intracellular transport of calcium ion in cardiomyocytes of rat was investigated. The experiments were performed on isolated papillary muscles of Wistar rats. Force-frequency dependence (0.7, 1, 2, 3, 4 Hz), extrasystolic and postextrasystolic contractions and post-rest (4-60 s) reactions of rat myocardium after amiodarone treatment (1 μM) were investigated. Decay potentiation coefficient of contraction force was estimated. Results. The analyses of force-frequency dependence has shown that amiodarone prevent the decreasing of the force contraction at increasing of the stimulation frequency. Amiodarone promotes increase of the time constant t1(T50), that indicate the drug promotes acceleration of Са2+ transport inside the SR resulting increase of Са2+ in the places of its release from the sarcoplasmic reticulum (SR). Treatment of papillary muscle with amiodarone decreased amplitude of extrasystolic contractions. As known, postextrasystolic and post-rest reactions of myocardium characterize the SR function. We have found amiodarone increased potentiation of postextrasystolic and post-rest contractions. preliminary caffeine perfusion of muscles preparations cancelled the amiodarone-induced increasing postextrasystolic and post-rest potentiation. However, potentiation decay coefficient before and after treatment with amiodarone didn’t have difference. Conclusions, amiodarone influences on intracellular calcium ions homeostasis by modulation SR functions related with most likely are stipulated either by activation of Са2+ transport from uptake sites to release sites or by prevent of Са2+ leakage from the SR.

关键词： Amiodarone Sarcoplasmic Reticulum Function postextrasystolic and post-Rest Contractions papillary Muscles of Rat

Modulation of Interval–Force Dependence of Rat papillary Muscle at Acute and Course Exposure of Amiodarone

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pharmacology & pharmacy 2012年第3期3卷 342-347页

作者： Sergey afanasiev Dina Kondratyeva Sergey popov Roman Batalov Federal State Budgetary Institution Research Institute for Сardiology of Siberian Branch under the Russian Academy of Medical Sciences Tomsk Russia.

Change of interval–force dependence of rat papillary muscles at acute and course use of amiodarone was investigated. Methods. The experiments were performed on isolated papillary muscles of Wistar rats. The extrasystolic (0,2-1,5 s), postextrasystolic contractions and post-rest (4-60 s) reactions of rat left papillary muscles perfused Krebs-Henseleit solution with amiodarone (1 μM) and papillary muscles of rat treated amiodarone in dose 20 mg/kg/day for 14 days were investigated. Results. It has been found that both acute and course use of amiodarone decreases the amplitude of extrasystolic contraction. At the same time, only acute use of amiodarone leads to additional enhancement of potentialtion of contractile response at extrasystolic impulse and performance of post-rest test. Conclusion was made, that both acute and course use of amiodarone decreases excitability of cardiomyocytes but only at course use this antiarrythmic drug increases effective refractory period of myocardium. Acute exposure of amiodarone is accompanied with change of functional state of cardiomyocyte sarcoplasmatic reticulum.

关键词： Acute and Course Amiodarone Sarcoplasmic Reticulum Function postextrasystolic and post-Rest Contractions papillary Muscles of Rat

The problems of Inaccuracy in Flow Capacity Definition by Using Different Numerical Techniques

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Journal of Thermal Science 2004年第1期13卷 1-7页

作者： I.V.afanasiev A.V.Granovski A.M.Kareline M.K.Kostege ALSTOM pOWER Uniturbo Ltd.13 Kasatkina St. 129301MoscowRussiaALSTOM POWER Uniturbo Ltd.13 Kasatkina St.129301MoscowRussiaALSTOM POWER Uniturbo Ltd.13 Kasatkina St.129301MoscowRussiaALSTOM POWER Uniturbo Ltd.13 Kasatkina St.129301MoscowRussia

The results of numerical analysis of turbine flow capacity and other parameters at different turbine rows are presented in this paper. Mass flow calculations by 3D Euler code has been controlled by means of 3D Navier-Stokes code taking into account inlet turbulence intensity and turbulence scale. The use of complicated numerical approaches (3D Euler or 3D Navier-Stokes codes) for mass flow definition demands close attention to quality of numerical techniques. Various reasons of inaccuracy of mass flow definition by using different 3D numerical approaches are analyzed.

关键词： flow capacity computing accuracy 3D Euler code 3D Navier-Stokes code.

Age changes of antyoxidant system and free-radical processes in rats at formation of postinfarction cardiosclerosis

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Advances in Aging Research 2013年第1期2卷 51-56页

作者： Tatiana Rebrova Sergey afanasiev Olesia putrova Roman Batalov Sergey popov Federal State Budgetary Institution “Research Institute for Сardiology” of Siberian Branch The Russian Academy of Medical Sciences Tomsk Russia

Estimation of age dependent changes of the lipid peroxidation (LpO) intensity, content of stable metabolites of nitrogen oxides (NO) and antioxidant enzyme activities in rat blood serum in conditions of experimental postinfarction cardiosclerosis (pICS) is carried out. Initiation of the postinfarction remodeling of animals has been carried out with coronary occlusion, definition of LpO and NO metabolites indices has been performed after 45 days. Investigations have been carried out on 40 four and twelve-month-old male Wistar rats with mass 200-250 gand 400 -450 g, accordingly. Statistical analysis of the results was performed using the Mann-Whitney-Wilcoxone criterion. It has been found that already intact animals have age specificity of indices under consideration. The expressed activity of LpO processes on the background of reduction of endogenous fermentative antioxidant (SOD and catalase) activity as well as nitrite concentration in blood serum is characteristic for pICS of 4-month-old animals. pICS of 12 month-old rats is accompanied with suppression of the LpO processes on the back- ground of reduction of the antioxidant enzyme intensity and increase of NO metabolites production. The following conclusions have been drawn. process of ontogenesis is characterized by imbalance between pro-and antioxidant processes in rat blood. Increase in catalase activity and concentration of the TBC-active products at simultaneous decrease of SOD activity and content of diene conjugates has been noted. The organism of young animals responds with persistent increase of LpO processes and decrease of SOD and catalase activity on formation of postinfartion cardioslerosis. The less expressed increase of lipid peroxidation activation and decrease of catalase activity has been noted in the organism of old animals within 45 day after pICS formation.

关键词： Lipid peroxidation Nitrogen Oxide postinfarction Cardiosclerosis Age-Related Aspect

possible mechanism of increasing resistance of the myocardium during combination of post infarction remodeling and diabetes mellitus

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Natural Science 2011年第4期3卷 295-300页

作者： M. V. Egorova S. A. afanasiev D. S. Kondratyeva B. N. Kozlov S. V. popov Laboratory of Molecular Cell pathology and Genetic Diagnosis Research Institute of Cardiology Siberian Branch of Russian Academy of Medical Science

It was shown that the energy metabolism of the heart mitochondria of experimental animals and patients is more resistant to damage at combined postinfarction cardiosclerosis and diabetes in comparison with the individual pathology. We found that the changes of free fatty acid content and conjugation of the processes of oxidation and phosphorylation in heart mitochondria are components of the metabolic stability of myocardium at the combined development of postinfarction cardiosclerosis and diabetes mellitus. Our data demonstrate a direct link between the violations of the processes of oxidative phosphorylation and accumulation of free fatty acids owing to change in activity of endogenous phospholipases, in particularly, mi- tochondrial phospholipase A2. Similar results were obtained for intraoperative biopsy specimens of patients’ hearts, and of adult Wistar rats’ hearts. We hypothesized that the preservation of energy metabolism is a manifestation of summing up of compensatory processes at de- velopment of nonspecific response of cells to damage at the early stages of pathological pro- cess.

关键词： postinfarction Remodeling Diabetes Heart Mitochondria Fatty Acids phospholipase A2