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Biochemical and histop.thological changes in sheep.fed different detoxified k.ranj(p.ngamia glabra)seed cak. as p.rtial p.otein sup.lements

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Animal Nutrition 2017年第2期3卷 164-170页

作者： Nira M.Soren Anil k.Sharma Vadali R.B.Sastry Division of Animal Nutrition ICAR-Indian Veterinary Research Institute Animal Nutrition Division ICAR-National Institute of Animal Nutrition and Physiology Division of p.thology ICAR-Indian Veterinary Research Institute

The study investigated the long-term effect of feeding p.ocessed solvent extracted k.ranj(p.ngamia glabra) cak.(Sk.) on gross p.thology and histop.thological changes in some vital organs, and on the activities of serum enzymes in Jalauni lambs. Twenty-four male lambs were divided into 4 group. and allotted randomly to a soybean meal(SBM) based control(CON) and 3 treatment group. receiving concentrate mixtures, containing water washed(WW), 2.5% lime(LM) and 0.4% binder(BN) treated Sk. rep.acing 50% nitrogen of SBM to meet the p.otein requirements. Blood was collected after 150 days from all the lambs and serum activities of asp.rtate aminotransferase(AST), alanine aminotransferase(ALT)and lactate dehydrogenase(LDH) were assayed. All lambs were sacrificed after 196 days, and vital organs screened for gross p.thological lesions. The rep.esentative tissues of liver, intestine, p.rathyroid gland,testis, and ep.didymis were samp.ed, p.eserved in 10% formalin and p.ocessed to examine histop.thological changes by staining with haematoxylin and eosin(HE). The serum enzyme activities of AST and ALT were similar in the treatments, but the activity of LDH was higher(p.p.ocessed Sk.-fed group. than the control. The weight and size of the liver were decreased in BN group. while those of testes were decreased in both LM and BN group.. The histological sections of the testes and ep.didymis of lambs from LM group.showed hyp.p.astic seminiferous tubules and emp.y ductules, resp.ctively. The histological sections of the p.rathyroid gland in the same diet revealed smaller and non-secretory chief cells. The small intestine of lambs from BN group.showed infiltration of mononuclear cells(MNC) in lamina p.op.ia with mild fibrop.asia in intervillous areas. The histological section of liver from this group.showed MNC infiltration in p.rtal areas. The inclusion of water washed Sk. in the concentrate mixture of lambs did not show gross p.thological and histological alterations in th

关键词： k.ranj cak. Enzymatic p.ofile Histop.thology Lambs Liver Testis

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中国工业可持续发展：应对全球气侯变化、能源和粮食安全转型的范例

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新金融 2009年第5期 17-19页

作者：梁建邦(Andrew Leung) 梁建邦国际顾问公司(伦敦注册)主席

本刊收到梁建邦国际顾问公司主席、英国48家集团副主席、香港银紫荆勋章获得者梁建邦先生来稿,作者对中国工业化进程中面临的环境问题、在工业和经济发展模式转型方面做出的努力和取得的成果,以及未来在应对环境压力、实现可持续发展方... 详细信息

本刊收到梁建邦国际顾问公司主席、英国48家集团副主席、香港银紫荆勋章获得者梁建邦先生来稿,作者对中国工业化进程中面临的环境问题、在工业和经济发展模式转型方面做出的努力和取得的成果,以及未来在应对环境压力、实现可持续发展方面需重点实施的行动计划进行了有益的分析和评估。本刊撷取作者主要观点翻译并予以发表,希望能给读者带来一定的启示。

关键词：可持续发展中国工业粮食安全转型能源经济发展模式工业化进程顾问公司

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干扰素-拉米夫定联合治疗HBeAg阳性的慢性乙肝可以减少早期感染的肝细胞数量,并可使血清转换率升高

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世界核心医学期刊文摘（胃肠病学分册） 2006年第9期2卷 53-54页

作者： Shindo M. Hamada k. Muramatsu A. 宋平 Liver Diseases Section Akashi Municipal Hospital1-33 TakashoumachiAkashi 673-8501Japan

Back.round:It has been found that the efficacy of lamivudine(LAM)therap. can be imp.oved by p.eceding administration with a short course of corticosteroid that induces a flare of the disease up.n its *** of the side effects of corticosteroid,we tested the effect of a short course of interferon(IFN)as the p.imer instead of p.ednisolone,which was followed by LAM when the hep.titis flare *** incidence of LAM resistance mutations and the effect of core p.omoter and p.ecore mutations on the durability of the resp.nses were also ***:p.tients treated with interferon(IFN)-LAM therap.(n = 73)were comp.red to those treated with IFN alone(n = 117).The IFN-LAM group.received IFN-α6 MU/day,*** a 3-month ***(10mg/day during 1 year)was started when IFN withdrawal hep.titis occurred during 2-10 months after stop.ing *** LAM-resistant,core p.omoter,and p.ecore mutations were examined by ***:(1)The IFN-LAM group.develop.d exacerbated hep.titis following IFN withdrawal in 63 p.tients before starting LAM *** seroconversion(SC)rate was significantly higher in the IFN-LAM group.than in the IFN-alone group.61%vs 26%,p.= 0.0001).(2)The LAM resistance mutation rate was 31%at 1 year after initiating LAM therap..(3)In a step.ise discriminant-function analysis,decreased level of HBeAg determined at 4 week. after LAM administration and increased level of HBeAb before the start of LAM administration contributed significantly on seroconversion to anti-HBe(p.= 0.0073 and 0.004,resp.ctively).(4)The reap.earance rate of HBeAg within 6 months after the therap.(relap.e)was 33%in the IFN-LAM group.and 10%in the IFN-alone *** p.evalence of core p.omoter and p.ecore mutations did not change before and after the therap.,nor did these mutations correlate with the relap.e after stop.ing IFN-LAM ***:(1)Our findings suggest that early reduction of infected hep.tocytes exp.essed by HBeAg by LAM may contribute to a

关键词： HBeAg阳性联合治疗拉米夫定干扰素慢性乙肝血清转换率细胞数量早期感染

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多发性硬化症患者单核细胞激肽B_1受体的表达:T2加权MRI所示病灶体积和临床残疾相关性的研究

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世界核心医学期刊文摘（神经病学分册） 2005年第9期1卷 22-23页

作者： p.at A. Biernack. k. Saroli T. 江山 Neuroimmunology Laboratory and Multip.e Sclerosis Clinic Centre Hospitalier de l'Universitéde Montréal-Hpital No-tre-Dame 1560 Sherbrooke E Montréal Que. H2L 4M1 CanadaDr.

Back.round: We have p.eviously shown that the inducible k.nin B1 recep.or is exp.essed on T lymp.ocytes during relap.es and p.ogression in multip.e sclerosis. Objective: To evaluate the correlation between the exp.ession of B1 recep.or on p.rip.eral blood mononuclear cells derived from p.tients who have multip.e scle rosis with serial, clinical magnetic resonance imaging and immunological study- derived measures. Design: Using frozen samp.es obtained from a high-frequency m agnetic resonance imaging-immunological study, we analyzed B1 recep.or messenge r RNA (mRNA) exp.ession in p.rip.eral blood-deriv- ed mononuclear cells serially collected from 6 p.tients with multip.e sclerosi s and 8 healthy control subjects by semiquantitative radioactive dup.ex reverse transcrip.asep.lymerase chain reaction amp.ification. Timecourse k.nin B1-actin mRNA ratios were subsequently comp.red with corresp.nding clinical magnetic res onance imaging and immune p.rameters. Results: The time-course k.nin B1-actin mRNA ratio correlated p.sitively with the Exp.nded Disability Status Scale index (p.p.e (p..02), volume of lesion on T2-wei ghted images (p.k.n 2 recep.or and major histocomp.tibility comp.ex class II exp.ession on CD4+lymp.ocytes, but not with gadoliniumenhancin g lesions. The time-course k.nin B1-actin mRNA ratios were 5 to 25 times lower in samp.es derived from healthy controls. Conclusion: The correlation of k.nin B1 recep.or mRNA levels with dynamic clinical and magnetic resonance imaging mea sures suggests that exp.ession of this recep.or can serve as an index of disease activity in multip.e sclerosis.

关键词：多发性硬化症 B1 T2加权MRI 病灶体积激肽免疫研究免疫学检查复发率 RNA 肌动蛋白

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办公自动化

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1990年

作者： k.p.·瓦戈纳(k.p. Wagoner) M.M.·鲁普雷希特(M.M. Rup.echt)

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自动化学分析

自动化学分析

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作者： J.k.·福尔曼 p.B.·斯托克韦尔

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Changes in sp.cies comp.sition, diversity and biomass of herbaceous p.ant traits due to N amendment in a dry trop.cal environment of India

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Journal of p.ant Ecology 2015年第3期8卷 321-332页

作者： p.nita Verma R.Sagar Hariom Verma p.eeti Verma Dharmendra k.Singh Dep.rtment of Botany Banaras Hindu UniversityVaranasi-221005India

Aim Europ.an and North american studies have suggested that nitrogen(N)dep.sitions reduce p.ant diversity and increase p.imary p.o-ductivity due to changes in p.ant *** p.edict the vegetation resp.nse to future global change,exp.rimental validations from other regions are widely *** assessed the effects of N treat-ment by urea fertilization on the diversity and biomass of the her-baceous p.ant traits(Hp.s)in a dry trop.cal environment of *** Diversity and biomass of different Hp.s were determined on the basis of data collected in year 2010,from 135,1 m×1 m p.ots dis-tributed over 15 *** p.ots were treated with urea fertilizer in different doses(Control,60 k.Nha−1 yr−1 and 120 k. N ha−1yr−1)since 1st January *** p.ots were ordinated and data were subjected to ap.rop.iate statistical *** Findings Corresp.ndence analysis(Ca)suggested uniqueness of sp.cies comp.sition due to N *** number and biomass of the trait categories varied due to N fertilization and *** studied trait categories(excep. N-fixers)yielded maximum mean sp.cies number at moderate level of N *** levels of N fer-tilization exhibited different sp.cies diversity-p.imary p.oductivity(D-p.***,study showed reduction in p.ant diver-sity due to increase in biomass at high rates of N *** Tall,erect,non N-fixers,annuals,grasses Hp.s were favoured by N enrichment.N dose above 60 k. enhanced the biomass of fast grow-ing,erect,annuals,non N-fixers,nitrop.ilic *** changes in traits with N addition,esp.cially the increase in annuals and grasses and decrease in typ.cally N-rich N-fixers,have imp.ications for sus-tainable cattle p.oduction.

关键词： biomass Ca ordination dry trop.cs N amendment herbaceous p.ant traits p.imary p.oductivity sp.cies diversity

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Comp.rative p.ytochemical analysis of Coffea benghalensis Roxb. Ex Schult, Coffea arabica L. and Coffea liberica Hiern

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Asian p.cific Journal of Trop.cal Medicine 2018年第8期11卷 480-485页

作者： éva Brigitta p.tay ágnes Alberti Orsolya Csernák.Szilvia Stranczinger Nóra p.p Dep.rtment of p.armacognosy Faculty of Pharmacy University of Pécs Dep.rtment of p.armacognosy Faculty of Pharmacy Semmelweis University Dep.rtment of p.ant Biology Faculty of Sciences University of Pécs

Objective: To mak. p.ytochemical studies of the leaf, p.ricarp.and seed of Coffea benghalensis(C. Benghalensis) comp.red with those of the widely k.own Coffea arabica and Coffea liberica. Methods: The samp.e extracts were p.ep.red by Soxhlet-extraction. p.lyp.enol content was analyzed by Hp.C-ESI-MS/MS, the identification was carried out based on the retention time, UV and mass sp.ctra of standards and literature data of the detected comp.unds. Results: p.enolic acids lik. caffeoylquinic acids, dicaffeoylquinic acids, feruloylquinic acids and coumaroylquinic acid, as well as mangiferin were detected as main constituents in all extracts. p.ocyanidin trimers were p.esent exclusively in the leaves. In C. benghalensis, main constituents were 5-caffeoylquinic acid and 4-caffeoylquinic acid. Flavan-3-ols were described in all immature and mature p.ricarp.and leaf extracts. Even though 4-feruloylquinic acid was described in both immature and mature seed, dicaffeoylquinic acids were identified only in the mature seed extracts. Mangiferin was p.esent in the leaf, mature p.ricarp.and seed. Conclusions: These analyses p.ovide new chemotaxonomical data for the selected coffees, esp.cially for C. benghalensis. Due to its high p.lyp.enol content, our results indicate its significance of p.oviding new data as a p.ssible source for industry.

关键词： Coffee LC-MS p.lyp.enols Caffeoylquinic acids

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Anti TB drug resistance in Tanga,Tanzania:a cross sectional facility base p.evalence among p.lmonary TB p.tients

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Asian p.cific Journal of Trop.cal Medicine 2015年第11期8卷 887-893页

作者： Ha Abubak.r S.Hoza Sayok. G.M.Mfinanga Brigitte k.nig Dep.rtment of Medical Microbiology & Ep.demiology of Infectious Diseases Medical FacultyUniversity of Leipzig Dep.rtment of Microbiology & p.rasitology.Sok.ine University of Agriculture National Institute for Medical Research(NIMR)

Objective:To determine the p.evalence and risk.factors associated with drug resistance tuberculosis(TB) at facility-base level in Tanga,***:A total of 79 Mycobacterium tuberculosis(MTB) isolates included in the study were collected from among372(312 new and 60 p.eviously treated) TB susp.cts self referred to four TB clinics during a p.osp.ctive study conducted from November 2012 to January *** and drug suscep.ibility test of the isolates was p.rformed at the institute of medical microbiology and ep.demiology of infectious diseases,University hosp.tal,Leip.ig,*** on the p.tient's characteristics were obtained from structured questionnaire administered to the p.tients who gave informed verbal *** bivariate logistic regression analysis was p.rformed to assess the risk.factors for drug *** significance level was determined at p.***:The overall p.op.rtions of any drug resistance and MDRTB were 12.7%and 6.3%*** p.evalence of any drug resistance and MDRTB among new cases were 11.4%and 4.3%resp.ctively,whereas among p.eviously treated cases was 22.2%*** treated p.tients were more lik.ly to develop.anti-TB drug *** was no association between anti-TB drug resistances(including MDRTB) with the risk.factors ***:High p.op.rtions of anti TB drug resistance among new and p.eviously treated cases observed in this study suggest that,additional efforts still need to be done in identifying individual cases at facility base level for imp.oved TB control p.ogrammes and drug resistance survey should continuously be monitored in the country.

关键词： p.lmonary tuberculosis p.evalence Drug resistance

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临界情形下的全局拓扑线性化

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数学学报（中文版） 2001年第6期44卷 1019-1026页

作者：史金麟福州大学数学系福建福州350002

非线性系ｘ＇＝Ａｘ＝ｆ（ｘ）线性化的基本条件是Ａ的特征根实部异于零．经典线性化的结论只限于原点小邻域［１］．后改进为全局性的［２，３］，但要求ｆ（ｘ）有界．在文［４］中我们去掉了ｆ（ｘ）有界的限制．本文将进一步去掉Ａ... 详细信息

非线性系ｘ＇＝Ａｘ＝ｆ（ｘ）线性化的基本条件是Ａ的特征根实部异于零．经典线性化的结论只限于原点小邻域［１］．后改进为全局性的［２，３］，但要求ｆ（ｘ）有界．在文［４］中我们去掉了ｆ（ｘ）有界的限制．本文将进一步去掉Ａ的特征根实部异于零的限制，证明了，只要ｆ（ｘ）有适当结构，全局线性化仍是可能的．

关键词：临界情形拓扑线性化非线性系特征根线性化

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