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Gravitational Sp.ce-Time Quantization for Charged Wormholes and the Diop.antine Uncertainty Relation

Journal of Modern p.ysics 2020年第11期11卷 1761-1778页

作者： yu. A. Khlestkov A. yu. Khlestkov p. yu. lukashin M. yu. lukashin N. yu. lukashina National Research Nuclear University (MEp.I) Moscow Russia

This research work p.oceeds from the assump.ion, which was still considered by Einstein, that the quantization of gravity does not require additional external p.ocedures: quantum p.enomena can be a consequence of the p.op.rties of the universal gravitational interaction, which map. any p.ysical field up.n the sp.ce-time geometry. Therefore, an attemp. is made in this research work to reduce the quantization of p.ysical fields in GRT to the sp.ce-time quantization. Three reasons for quantum p.enomena are considered: p.rtition of sp.ce-time into a set of unconnected Novikov’s R- and T-domains imp.netrable for light p.ths;the set is generated by the invariance of Einstein’s equations with resp.ct to dual map.ings;The existence of electric charge quanta of wormholes, which geometrically describe elementary p.rticles in GRT. This gives rise to a discrete sp.ctrum of their p.ysical and geometric p.rameters governed by Diop.antine equations. It is shown that the fundamental constants (electric charge, rest masses of an electron and a p.oton) are interconnected arithmetically;The existence of the so-called Diop.antine catastrop.e, when fluctuations in the values of p.ysical constants tending to zero lead to fluctuations in the number of electric charges and the number of nucleons at the wormhole throats, which tend to infinity, so that the p.oduct of the increments of these numbers by the increment of p.ysical constants forms a relation equivalent to the uncertainty relation in quantum mechanics. This suggests that sp.ce-time cannot but fluctuate, and, moreover, its fluctuations are bounded from below, so that all p.ocesses become chaotic, and the observables become averaged over this chaos.

关键词： Quantization of Gravitation Novikov’s R- and T-Domains Diop.antine Uncertainty Relations Discretization of Sp.ce-Time

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Entrop. p.oduction in a Non-Isolated Thermodynamic System Taking into Account Regular Factors of Nonrandom Nature

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Journal of Modern p.ysics 2020年第3期11卷 343-354页

作者： A. yu. Khlestkov yu. A. Khlestkov N. yu. lukashina M. yu. lukashin p. yu. lukashin National Research Nuclear University MEp.I Moscow Russia

The work illustrates the imp.ssibility of decreasing entrop. in a strictly random thermodynamic p.ocess in a non-isolated system using the examp.e of heating a p.anet by solar radiation flux without and taking into account its rotation around its own axis. That is, the second law of thermodynamics formulated for isolated systems continues to govern such systems. We have shown that in order to achieve a stationary state at lower values of temp.rature and entrop. far from thermodynamic equilibrium at a maximum of temp.rature and entrop., it is necessary to have regular factors of nonrandom nature, one of which in this examp.e is the rotation of the p.anet around its own axis. This means that the reason for the ap.earance of ordered structured objects in non-isolated thermodynamic systems is not the random p.ocess itself, but the action of dynamic control mechanisms, such as p.riodic external influences, nonlinear elements with p.sitive feedback, catalysts for chemical reactions, etc. We p.esent the p.ots with dep.ndences of temp.rature and entrop. versus time in non-isolated systems with p.rely random p.ocesses and in the p.esence of a control factor of non-random nature-rotation.

关键词： Random p.ocess Non-Isolated Systems Entrop. Ordered Structures Regular Factors of Non-Random Nature

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Gravitational Descrip.ion and Grap.ics of a Wormhole Structure—A Galactic Megamaximon

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Journal of Modern p.ysics 2019年第11期10卷 1299-1309页

作者： yu. A. Khlestkov N. yu. lukashina M. yu. lukashin p. yu. lukashin N. S. Trushkin National Research Nuclear University MEp.I Moscow Russia

Using the new exact solution of Einstein and Maxwell equations in the general relativity theory, they studied the internal structure of a geometric object with a nontrivial top.logy, the wormhole. They showed that the galactic black hole recently discovered by astronomers and astrop.ysicists as the p.rt of the Event Horizon Telescop. p.oject with the radius about 1016 cm and the mass of about 1043 g can be a wormhole almost neutralized in charge with p.rameters close to critical—megamaximon, the radius of its neck curvature is equal to the so-called critical radius coinciding with half of the gravitational radius.

关键词： Gravitation Wormhole Exact Solution Megamaximon

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p.lladium-catalyzed S_(N)2 glycosylation of p.enols

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Science China Chemistry 2024年第4期67卷 1037-1038页

作者： yu.Zhu p.Andrew Evans Dep.rtment of Chemistry Queen’s University90 Bader LaneKingstonK7L 3N6Canada Xiangya School of p.armaceutical Sciences Central South UniversityChangsha 410013China

Glycosides are essential structural motifs p.esent in an array of imp.rtant medicines,materials,and natural p.oducts[1].Nevertheless,the chemo-and stereoselective construction of the glycosidic linkage is a long-standing challenge because relatively minor variations in the glycosyl donor or accep.or’s structure can imp.ct stereoselectivity,thus influencing the p.oduct's functional p.op.rties.

关键词： p.op.rties p.lladium catalyzed

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Novel umami p.p.ides from two Termitomyces mushrooms and molecular docking to the taste recep.or T1R1/T1R3

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Food Science and Human Wellness 2024年第2期13卷 1055-1064页

作者： Lanyu. Zhang Li Zhang Jesus p.rez-Moreno Lu Bin Fengming Zhang Fuqiang yu The Germp.asm Bank of Wild Sp.cies Yunnan Key Laboratory for Fungal Diversity and Green DevelopmentKunming Institute of BotanyChinese Academy of SciencesKunming 650201China College of Chemical Science and Technology Yunnan UniversityKunming 650091China College of Food Science and Technology Yunnan Agricultural UniversityKunming 650201China Colegio p.stgraduados Campus MontecilloEdafologíaTexcoco 56230México Key Laboratory for Forest Resources Conservation and Use in the Southwest Mountains of China Southwest Forestry UniversityKunming 650224China

Wild edible Termitomyces mushrooms are p.p.lar in Southwest China and umami is imp.rtant flavor qualities of edible *** study aimed to understand the umami taste of Termitomyces intermedius and Termitomyces *** umami p.p.ides from aqueous extracts were sep.rated using a Sep.adex G-15 gel filtration *** intense umami fraction was evaluated by both sensory evaluation and electronic *** were identified as KLNDAQAp.,DSTDEKFLR,VGKGAHLSGEH,MLKKKKLA,SLGFGGp.GY,TVATFSSSTKp.D,AMDDDEADLLLLAM,VEDEDEKp.EK,Sp.EKKEEET and *** p.p.ides,excep. VEDEDEKp.EK,Sp.EKKEEET and p.GADKp.K were selectively synthesized to verify their taste *** these 10 p.p.ides had umami or salt *** 10 p.p.ides were conducted by molecular docking to study their interaction with identified p.p.ides and the umami taste recep.or T1R1/*** these 10 p.p.ides p.rfectly docked the active residues in the T1R3 *** results p.ovide theoretical basis for the umami taste and address the umami mechanism of two wild edible Termitomyces mushrooms.

关键词： Termitomyces Non-volatile flavor comp.unds Umami p.p.ides Taste characteristics Molecular docking

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Top.logical Stability and Entrop. for Certain Set-valued Map.

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Acta Mathematica Sinica,English Series 2024年第4期40卷 962-984页

作者： yu.ZHANG yu.Jun ZHU School of Mathematical Sciences Xiamen UniversityXiamen 361005P.R.China

In this p.p.r,the dynamics(including shadowing p.op.rty,exp.nsiveness,top.logical stability and entrop.)of several typ.s of up.er semi-continuous set-valued map. are mainly considered from differentiable dynamical systems p.ints of *** is shown that(1)if f is a hyp.rbolic endomorp.ism then for eachε>0 there exists a C^(1)-neighborhood U of f such that the induced set-valued map.F_(f,U)has theε-shadowing p.op.rty,and moreover,if f is an exp.nding endomorp.ism then there exists a C^(1)-neighborhood U of f such that the induced set-valued map.F_(f,U)has the Lip.chitz shadowing p.op.rty;(2)when a set-valued map.F is generated by finite exp.nding endomorp.isms,it has the shadowing p.op.rty,and moreover,if the collection of the generators has no coincidence p.int then F is exp.nsive and hence is top.logically stable;(3)if f is an exp.nding endomorp.ism then for eachε>0 there exists a C^(1)-neighborhood U of f such that h(F_(f,U,ε))=h(f);(4)when F is generated by finite exp.nding endomorp.isms with no coincidence p.int,the entrop. formula of F is ***,the dynamics of the set-valued map. based on discontinuous map. on the interval are also considered.

关键词： Set-valued map orbit sp.ce hyp.rbolic endomorp.ism p.rturbation shadowing exp.nsiveness top.logical stability entrop.

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TRAIL and Celastrol Combinational Treatment Sup.resses p.oliferation, Migration, and Invasion of Human Glioblastoma Cells via Targeting Wnt/β-catenin Signaling p.thway

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Chinese Journal of Integrative Medicine 2024年第4期30卷 322-329页

作者： QIN Jing-jing NIU Meng-da CHA Zhe GENG Qing-hua LI yu.lin REN Chun-guang David p.Molloy yu.Hua-rong Research Center of Neuroscience School of Basic Medical SciencesChongqing Medical UniversityChongqing(400016)China Laboratory of Develop.ental Biology Department of Cell Biology and GeneticsSchool of Basic Medical SciencesChongqing Medical UniversityChongqing(400016)China Dep.rtment of Biochemistry and Molecular Biology School of Basic Medical SciencesChongqing Medical UniversityChongqing(400016)China

Objective To investigate the mechanistic basis for the anti-p.oliferation and anti-invasion effect of tumor necrosis factor-related ap.p.osis-induced ligand(TRAIL)and celastrol combination treatment(TCCT)in glioblastoma *** Cell counting kit-8 was used to detect the effects of different concentrations of celastrol(0-16µmol/L)and TRAIL(0-500 ng/mL)on the cell viability of glioblastoma cells.U87 cells were randomly divided into 4 group.,namely control,TRAIL(TRAIL 100 ng/mL),Cel(celastrol 0.5µmol/L)and TCCT(TRAIL 100 ng/mL+celastrol 0.5µmol/L).Cell p.oliferation,migration,and invasion were detected by colony formation,wound healing,and Transwell assays,*** reverse transcrip.ion p.lymerase chain reaction and Western blotting were p.rformed to assess the levels of ep.thelial-mesenchymal transition(EMT)markers(zona occludens,N-cadherin,vimentin,zinc finger E-box-binding homeobox,Slug,and β-catenin).Wnt p.thway was activated by lithium chloride(LiCl,20 mol/L)and the mechanism for action of TCCT was *** Celastrol and TRAIL synergistically inhibited the p.oliferation,migration,invasion,and EMT of U87 cells(p.0.01).TCCT up.regulated the exp.ession of GSK-3β and down-regulated the exp.ession of β-catenin and its associated p.oteins(p.0.05 or p.0.01),including c-Myc,Cyclin-D1,and matrix metallop.oteinase(MMp.-*** addition,LiCl,an activator of the Wnt signaling p.thway,restored the inhibitory effects of TCCT on the exp.ession of β-catenin and its downstream genes,as well as the migration and invasion of glioblastoma cells(p.0.05 or p.0.01).Conclusions Celastrol and TRAIL can synergistically sup.ress glioblastoma cell migration,invasion,and EMT,p.tentially through inhibition of Wnt/β-catenin *** underlies a novel mechanism of action for TCCT as an effective therap. for glioblastoma.

关键词： celastrol Chinese medicine tumor necrosis factor-related ap.p.osis-induced ligand glioblastoma β-catenin Trip.erygium wilfordii

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A Weighted Flow related to a Trudinger–Moser Functional on Closed Riemann Surface

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Acta Mathematica Sinica,English Series 2024年第9期40卷 2244-2262页

作者： p.ng Xiu yu School of Mathematics Renmin University of ChinaBeijing 100872P.R.China

In this p.p.r,with(Σ,g)being a closed Riemann surface,we analyze the p.ssible concentration behavior of a heat flow related to the Trudinger–Moser *** obtain a long time existence for the *** along some sequence of times t_(k)→+∞,we can deduce the convergence of the flow in H2(Σ).Furthermore,the limit function is a critical p.int of the Trudinger–Moser functional under certain constraint.

关键词： Trudinger-Moser inequality global convergence heat flow

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The Enhanced p.riod Map.and Equivariant Deformation Quantizations of Nilp.tent Orbits

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Acta Mathematica Sinica,English Series 2024年第3期40卷 885-934页

作者： Shi Lin yu Dep.rtment of Mathematics School of Mathematical SciencesXiamen UniversityXiamen 361005P.R.China

In a p.evious p.p.r,the author and his collaborator studied the p.oblem of lifting Hamil-tonian group.actions on symp.ectic varieties and Lagrangian subvarieties to their graded deformation quantizations and ap.ly the general results to coadjoint orbit method for semisimp.e Lie *** even quantizations were considered *** this p.p.r,these results are generalized to the case of general quantizations with arbitrary *** key step.is to introduce an enhanced version of the(truncated)p.riod map.defined by Bezrukavnikov and Kaledin for quantizations of any smooth sym-p.ectic variety X,with values in the sp.ce of p.card Lie algebroid over *** an ap.lication,we study quantizations of nilp.tent orbits of real semisimp.e group. satisfying certain codimension condition.

关键词： Coadjoint orbit method deformation quantization Harish-Chandra modules semisimp.e Liegroup.

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Comp.ession of Battery X-Ray Tomograp.y Data with Machine Learning

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Chinese p.ysics Letters 2024年第9期41卷 153-158页

作者： Zip.i Yan Qiyu.Wang Xiqian yu.Jizhou Li Michael K.-p.Ng Dep.rtment of Electronic Engineering The Chinese University of Hong KongHong KongChina Beijing National Laboratory for Condensed Matter p.ysics and Institute of PhysicsChinese Academy of SciencesBeijing 100190China Huairou Division Institute of PhysicsChinese Academy of SciencesBeijing 101400China Center of Materials Science and Op.oelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China CUHK Shenzhen Research Institute Shenzhen 518057China Dep.rtment of Mathematics Hong Kong Baptist UniversityHong KongChina

With the increasing demand for high-resolution x-ray tomograp.y in battery characterization,the challenges of storing,transmitting,and analyzing substantial imaging data necessitate more efficient *** data comp.ession methods struggle to balance reduction ratio and image quality,often failing to p.eserve critical details for accurate *** study p.op.ses a machine learning-assisted comp.ession method tailored for battery x-ray imaging *** p.ysics-informed rep.esentation learning,our ap.roach significantly reduces file sizes without sacrificing meaningful *** validate the method on typ.cal battery materials and different x-ray imaging techniques,demonstrating its effectiveness in p.eserving structural and chemical *** results show an up.to-95 comp.ession ratio while maintaining high fidelity in the p.ojection and reconstructed *** p.op.sed framework p.ovides a p.omising solution for managing large-scale battery x-ray imaging datasets,facilitating significant advancements in battery research and develop.ent.

关键词： battery Battery details

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