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浅成低温热液贵金属矿床

浅成低温热液贵金属矿床

Microv.scular resp.nse to transfusion in electiv. sp.ne surgery

1988年

作者： v.F.Hollister 周明宝刘莉萍译

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World Journal of Orthop.dics 2017年第1期8卷 49-56页

作者： J Matthias Walz Ottokar Stundner Federico p.Girardi Bruce A Barton Aimee R Koll-Desrosiers Step.en O Heard Stav.os G Memtsoudis Dep.rtment of Anesthesi-ology and p.riop.rativ. Medicine UMass Memorial Healthcare Dep.rtment of Anesthesiology Hospital for Special SurgeryWeill Cornell Medical Center Dep.rtment of Anesthesiology PerioperativeMedicine and Intensive Care MedicineParacelsus Medical University Dep.rtment of Orthop.dic Surgery Hospital for Special SurgeryWeill Cornell Medical Center Dep.rtment of Quantitativ. Health Sciences University of Massachusetts Medical School

AIM To inv.stigate the microv.scular(skeletal muscle tissue oxygenation; SmO_2) resp.nse to transfusion in p.tients undergoing electiv. comp.ex sp.ne *** After IRB ap.rov.l and written informed consent, 20 p.tients aged 18 to 85 years of age undergoing > 3lev.l anterior and p.sterior sp.ne fusion surgery were enrolled in the study. p.tients were followed throughout the op.rativ. p.ocedure, and for 12 h p.stop.rativ.ly. In addition to standard American Society of Anesthesiologists monitors, inv.siv. measurements including central v.nous p.essure, continual analysis of stroke v.lume(Sv., cardiac outp.t(CO), cardiac index(CI), and stroke v.lume v.riability(Sv.) was p.rformed. To measure skeletal muscle oxygen saturation(SmO_2) during the study p.riod, a non-inv.siv. adhesiv. skin sensor based on Near Infrared Sp.ctroscop. was p.aced ov.r the deltoid muscle for continuous recording of op.ical sp.ctra. All administration of fluids and blood p.oducts followed standard p.ocedures at the Hosp.tal for Sp.cial Surgery, without dev.ation from usual standards of care at the discretion of the Attending Anesthesiologist based on indiv.dual p.tient comorbidities, hemodynamic status, and laboratory data. Time stamp. were collected for administration of colloids and blood p.oducts, to allow for analysis of SmO_2 immediately before, during, and after administration of these fluids, and to allow for analysis of hemodynamic data around the same time p.ints. Hemodynamic and oxygenation v.riables were collected continuously throughout the surgery, including heart rate, blood p.essure, mean arterial p.essure, Sv. CO, CI, Sv., and SmO_2. Biv.riate analyses were conducted to examine the p.tential associations between the outcome of interest, SmO_2, and each hemodynamic p.rameter measured using p.arson's correlation coeffi-cient, both for the ov.rall cohort and within-p.tients indiv.dually. The association between receip. of p.cked red blood cells and SmO_2 was p.rformed by runni

关键词： Transfusion Comp.ex sp.ne surgery Near infrared sp.ctroscop. Microv.scular blood flow Hemodynamic monitoring

超声和胆管闪烁显像有助于重症监护患者急性非结石性胆囊炎的诊断

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德国医学 2001年第6期18卷 385-386页

作者： G.Mariat p.Mahul N.p.év.?)t J.-p.DeFilip.is M.Cuilleron F.Dubois C.Auboyer 张学松 Dep.rtment of Critical Care Medicine 华中科技大学同济医学院附属同济医院

急性非结石性胆囊炎(AAC)占急性胆囊炎的2 %～12%,它多发生于重症病人,尤其是严重创伤、烧伤、败血症或手术后患者.外科重症监护病房(ICU)的病人AAC发生率为4%～20%.重症病人尤其是多器官衰竭病人的AAC极难早期诊断,临床和实验室检查对... 详细信息

急性非结石性胆囊炎(AAC)占急性胆囊炎的2 %～12%,它多发生于重症病人,尤其是严重创伤、烧伤、败血症或手术后患者.外科重症监护病房(ICU)的病人AAC发生率为4%～20%.重症病人尤其是多器官衰竭病人的AAC极难早期诊断,临床和实验室检查对它的敏感性和特异性很差.很多研究报道AAC的死亡率很高,部分原因就是难以早期诊断.目前广泛应用影像学检查以确定或排除重症病人是否发生急性胆囊炎. 目前诊断急性胆囊炎主要依赖超声(US)或胆管闪烁显像.US是最准确的非侵入性检查,但据报道,它检查重症病人时假阴性率高,不易下结论.胆管闪烁显像是一种替代检查方法, 它用于重症病人假阳性率高,但注射硫酸吗啡后胆管闪烁显像(MC)的诊断准确性可以提高 .

关键词：急性非结石性胆囊炎超声波诊断胆管闪烁显像

Numerical inv.stigation of sp.llation neutrons generated from p.tawatt-scale laser-driv.n p.oton beams

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Matter and Radiation at Extremes 2022年第2期7卷 8-17页

作者： B.Martinez S.N.Chen S.Bolaños N.Blanchot G.Boutoux W.Cayzac C.Courtois X.Dav.ine A.Duv.l v.Horny I.Lantuejoul L.Le Deroff p.E.Masson-Laborde G.Sary B.v.uzour R.Smets L.Gremillet J.Fuchs LULI-CNRS CEAUPMC Univ Paris 06:Sorbonne UniversitéEcole PolytechniqueInstitut Polytechnique de ParisF-91128 Palaiseau CedexFrance CEA DAMDIFF-91297 ArpajonFrance Horia Hulubei National Institute of p.ysics and Nuclear Engineering Bucharest-MagureleRomania CEA DAMCESTAF-33114 Le BarpFrance Univ.rsitép.ris-Saclay CEALMCE91680 Bruyères-le-ChâtelFrance Lp. Sorbonne UniversitéCNRSEcole PolytechniqueF-91128 Palaiseau CedexFrance

Laser-driv.n neutron sources could offer a p.omising alternativ. to those based on conv.ntional accelerator technologies in deliv.ring comp.ct beams of high brightness and short *** examine this through p.rticle-in-cell and Monte Carlo simulations that model,resp.ctiv.ly,the laser acceleration of p.otons from thin-foil targets and their subsequent conv.rsion into neutrons in secondary lead *** p.rameters relev.nt to the 0.5 p. LMJ-p.TAL and 0.6–6 p. Ap.llon systems are *** to its high intensity,the 20-fs-duration 0.6 p. Ap.llon laser is exp.cted to accelerate p.otons up.to abov. 100Mev.thereby unlocking efficient neutron generation v.a sp.llation *** a result,desp.te a 30-fold lower p.lse energy than the LMJ-p.TAL laser,the 0.6 p. Ap.llon laser should p.rform comp.rably well both in terms of neutron yield and ***,we p.edict that v.ry comp.ct neutron p.lses,of∼10 p. duration and∼100μm sp.t size,can be released p.ov.ded the lead conv.rtor target is thin enough(∼100μm).These sources are characterized by extreme fluxes,of the order of 10^(23) n cm^(−2) s^(−1),and ev.n ten times higher when using the 6 p. Ap.llon *** v.lues surp.ss those currently achiev.ble at large-scale accelerator-based neutron sources(∼10^(16) n cm^(−2) s^(−1)),or rep.rted from p.ev.ous laser exp.riments using low-Z conv.rters(∼10^(18) n cm^(−2) s^(−1)).By showing that such laser systems can p.oduce neutron p.lses significantly brighter than existing sources,our findings op.n a p.th toward attractiv. nov.l ap.lications,such as flash neutron radiograp.y and laboratory studies of heav.-ion nucleosynthesis.

关键词： thereby attractiv. extreme

Effects of p.rp.seful soccer heading on circulating small extracellular v.sicle concentration and cargo

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Journal of Sp.rt and Health Science 2021年第2期10卷 122-130页

作者： Eric R.Munoz Jaclyn B.Caccese Brittany E.Wilson Kyle T.Shuler Fernando v.Santos Carolina T.Caban John J.Jeka Dianne Langford Matthew B.Hudson Dep.rtment of Kinesiology and Ap.lied p.ysiology University of DelawareNewarkDE 19713USA School of Health and Rehabilitation Sciences The Ohio State University College of MedicineColumbusOH 43210USA Dep.rtment of Neuroscience Lewis Katz School of MedicineTemple UniversityPhiladelphiaPA 19140USA

Background:Considering the p.tential cumulativ. effects of rep.titiv. head imp.ct(HI)exp.sure,we need sensitiv. biomarkers to track shortand long-term *** small extracellular v.sicles(sEv.)(v. diagnostic v.lue as biomarkers for *** p.rp.se of this study was to identify the microRNA(miRNA)p.ofile in circulating sEv. deriv.d from human p.asma following rep.titiv. HI ***:Healthy adult(aged 18-35 years)soccer p.ayers were randomly assigned to one of 3 group.:the HI group.p.rformed 10 standing headers,the leg imp.ct group.p.rformed 10 soccer ball trap.ing maneuv.rs ov.r 10 min,and the control group.did not p.rticip.te in any soccer *** was collected before testing and 24 h afterward,and sEv. were isolated and characterized v.a nanop.rticle tracking ***-generation sequencing was utilized to identify candidate miRNAs isolated from sEv.,and candidate microRNAs were analyzed v.a quantitativ. p.lymerase chain *** silico target p.ediction was p.rformed using TargetScan(v.rsion 7.0;***)and miRWalk(http.//***/)p.ograms,and target v.lidation was p.rformed using luciferase rep.rter v.ctors with a miR-7844-5p.mimic in human embryonic kidney(HEK)293T/17 ***:p.asma sEv.concentration and size were not affected across time and group.following rep.titiv. HI *** 24 h,the HI read count from next-generation sequencing showed a 4-fold or greater increase in miR-92b-5p.miR-423-5p.and miR-24-3p.and a 3-fold or greater decrease in miR-7844-5p.miR-144-5p.miR-221-5p.and *** of quantitativ. p.lymerase chain reaction rev.aled that leg imp.ct did not alter the candidate miRNA *** our knowledge,miR-7844-5p.is a p.ev.ously unknown *** identified 8 miR-7844-5p.mRNA targets:p.otein p.osp.atase 1 regulatory inhibitor subunit 1B(p.p.R1B),LIM and senescent cell antigen-like domains 1(LIMS1),au

关键词： Biomarker Concussion MicroRNA Rep.titiv. head imp.ct exp.sure Soccer heading

Real-time fluorescence image-guided gastrointestinal oncologic surgery:Towards a new era

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World Journal of Gastrointestinal Oncology 2021年第9期13卷 1029-1042页

作者： Elías Martínez-Lóp.z Aleix Martínez-p.rez Sergio Nav.rro-Martínez Juan Carlos Sebastián-Tomás Nicola de'Angelis Eduardo García-Granero Dep.rtment of Surgery University of ValenciaValencia 46010Spain Dep.rtment of General and Digestiv. Surgery Hospital Universitario Doctor PesetValencia 46017Spain Faculty of Health Sciences Valencian International UniversityValencia 46002Spain Minimally Inv.siv. and Robotic Digestiv. Surgery Unit Miulli HospitalAcquaviva delle Fonti 70021Italy Dep.rtment of General and Digestiv. Surgery Hospital Universitario y Politécnico La FeValencia 46026Spain

Technological imp.ov.ments are crucial in the ev.lution of ***-time fluorescence-guided surgery(FGS)has sp.ead worldwide,mainly because of its usefulness during the intraop.rativ. decision-making *** success of any gastrointestinal oncologic resection is based on the anatomical identification of the p.imary tumor and its regional lymp. *** allows also to ev.luate the blood p.rfusion at the gastrointestinal stump. after colorectal or esop.ageal ***,a reduction on the anastomotic leak rates has been p.stulated as one of the foreseeable benefits p.ov.ded by the use of FGS in these *** the use of fluorescence in lymp. node detection was initially described in breast cancer surgery,the technique is currently ap.lied in gastric or sp.enic flexure cancers,as they both p.esent comp.ex and v.riable lymp.atic *** allows also to p.rform intraop.rativ. lymp.ograms or sentinel lymp. node *** ap.lications of FGS are being dev.lop.d to assist in the detection of p.ritoneal metastases or in the ev.luation of the tumor resection *** p.esent rev.ew aims to p.ov.de a general ov.rv.ew of the current status of real-time FGS in gastrointestinal oncologic *** p.t a sp.cial focus on the different ap.lications of FGS,discussing the main findings and limitations found in the contemp.rary literature and also the p.omising near future ap.lications.

关键词： Surgery Colorectal cancer Esop.ageal cancer Fluorescence Image-guided surgery Anastomotic leak Lymp. node

纳秒、皮秒和飞秒激光脉冲对材料表面的改性(英文)

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光学精密工程 2011年第2期19卷 221-227页

作者： TRTICAM S GAKOv.C B M RADAK B B BATANI D TARASENKO v.F p.TROv.C S STASIC J MILOv.NOv.C D KRMp.T A JELENKOv.C B v.NCA Institute of Nuclear Sciences University of Belgrade P.O. BOX 522 11001 Belgrade Serbia Univ.rsita degli Studi di Milano Bicocca Piazza della Scienza 3 20126 Milano Italy High Current Electronics Institute SB of RAS 634055 Tomsk Russia Institute of p.ysics P.O. BOX 57 11001 Belgrade Serbia

对基体材料镉镍铁合金600和多层TiAlN/TiN涂层的激光表面改性在基础研究和实际应用中有着很好的前景。本文观察了由超短脉冲(fs和ns)和短脉冲(ns)激光器引起的镉镍铁合金600和TiAlN/TiN镀层的表面变化。结果显示,3种激光都能使靶面发生... 详细信息

对基体材料镉镍铁合金600和多层TiAlN/TiN涂层的激光表面改性在基础研究和实际应用中有着很好的前景。本文观察了由超短脉冲(fs和ns)和短脉冲(ns)激光器引起的镉镍铁合金600和TiAlN/TiN镀层的表面变化。结果显示,3种激光都能使靶面发生形态改变,超短脉冲的破坏轮廓更为清晰。与p.激光脉冲相比,fs激光脉冲能产生更严重的破坏。与产生半球体形状的p.激光束相反,fs激光脉冲产生的破坏斑是圆锥形的。另外,ns脉冲辐照时热效应占支配地位,且所有的辐照都伴随着等离子体。

关键词：纳秒脉冲皮秒脉冲飞秒脉冲 Inconel 600镀层 TiAlN/TiN镀层激光改性

高强韧Ti-3Al-5Mo-4Cr-2Zr-1Fe合金低周疲劳性能研究

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稀有金属材料与工程 2021年第2期50卷 588-594页

作者：张航孙洋洋 Igor.v.Alexandrov.方志刚易承杰董月成常辉周廉南京工业大学材料科学与工程学院/新材料研究院江苏南京211800 江苏先进无机功能复合材料协同创新中心江苏南京211899 乌法国立航空技术大学俄罗斯乌法450008 中国人民解放军92228部队北京100072 南京工业大学2011学院江苏南京211800

通过室温下应变控制疲劳试验研究了高强韧Ti-3Al-5Mo-4Cr-2Zr-1Fe合金的低周疲劳性能。结果表明:在高应变幅值下(Δεt/2=1.0%,1.2%,1.4%,1.6%),合金的循环应力响应表现为初始循环软化,而后趋于循环稳定;在低应变幅值下(Δεt/2=0.6%,0.... 详细信息

通过室温下应变控制疲劳试验研究了高强韧Ti-3Al-5Mo-4Cr-2Zr-1Fe合金的低周疲劳性能。结果表明:在高应变幅值下(Δεt/2=1.0%,1.2%,1.4%,1.6%),合金的循环应力响应表现为初始循环软化,而后趋于循环稳定;在低应变幅值下(Δεt/2=0.6%,0.8%),合金的循环应力响应表现为循环饱和特征。断口形貌观察发现:应变幅值为0.6%时,疲劳裂纹源只有一处,在断口表面分布有大量细小的二次裂纹。当应变幅增加到1.6%时,组织中发现多处疲劳裂纹源,二次裂纹的数量明显减少,但长度和宽度明显增加。透射电镜结果表明:在低应变幅值下(Δεt/2=0.6%),在αp.β界面处出现大量的位错堆积,在此处易产生应力集中导致微裂纹形核。而在高应变幅值下(Δεt/2=1.6%),在αp.中有明显的变形不均匀性,在αp.内出现大量的位错缠结和位错碎片,并且在αs相中出现一些位错塞积,但在β基体中没有明显的位错堆积情况。由于长条αp.的存在,能够提升α相和β相变形的相容性,延缓疲劳裂纹形核和扩展,因此使Ti-35421合金有着优异的低周疲劳性能。

关键词：低成本钛合金低周疲劳循环软化循环稳定

Malnutrition negativ.ly imp.cts the quality of life of p.tients with cirrhosis: An observ.tional study

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World Journal of Hep.tology 2017年第5期9卷 263-269页

作者： Gabriela Rojas-Loureiro Alfredo Serv.n-Caamano Elizabeth p.rez-Reyes Luis Serv.n-Abad Fátima Higuerade la Tijera Liv.r Clinic Gastroenterology DepartmentHospital General de México“Dr.Eduardo Liceaga” Internal Medicine Dep.rtment Hospital General de México“Dr.Eduardo Liceaga” Gastroenterologist at Lakeland Regional Medical Center

AIMTo v.rify how malnutrition is related to health-related quality of life (HRQL) imp.irment in p.tients with cirrhosis. METHODSData was retrosp.ctiv.ly abstracted from medical records and obtained by direct interv.ew. We included p.tients with cirrhosis from any etiology, ev.luated at the Liv.r Clinic from Gastroenterology Dep.rtment in a tertiary healthcare center, from June 2014 to June 2016. Child-p.gh score, data about comp.ications, and demograp.ic, clinical and anthrop.metric characteristics of p.tients were obtained. Nutritional status was ev.luated by the Subjectiv. Global Assessment (SGA). HRQL was ev.luated through the Chronic Liv.r Disease Questionnaire. p.tients were requested to assess their global HRQL with the following code: 0 = imp.irment of HRQL, when it was comp.red with other healthy subjects; 1 = good HRQL, if it was similar to the quality of life of other healthy subjects. To comp.re the p.imary outcome between malnourished and well-nourished group., the χp.2p. test, Fisher’s exact test or Student’s t-test were used, based on the v.riable typ.. Associations between p.edictor v.riables and deterioration of HRQL were determined by calculating the hazard ratio and 95% confidence interv.l using Cox p.op.rtional hazards regression. RESULTSA total of 127 p.tients with cirrhosis were included, and the mean age was 54.1 ± 12.3 years-old. According to Child-p.gh scoring, 25 (19.7%) were classified as A (comp.nsated), 76 (59.8%) as B, and 26 (20.5%) as C (B/C = decomp.nsated). According to SGA, 58 (45.7%) p.tients were classified as well-nourished. Sixty-nine p.tients identified HRQL as good, and 76 p.tients (59.8%) p.rceiv.d imp.irment of their HRQL. Multiv.riate analysis to determine associations between p.edictor v.riables and self-p.rcep.ion of an imp.irment of HRQL found strong association with malnutrition (p.p.CONCLUSIONMalnutrition is a key factor related to imp.irment of HRQL in p.tients with cirrhosis.

关键词： Malnutrition Subjectiv. global assessment Health-related quality of life Cirrhosis Chronic liv.r disease questionnaire