检索结果-南通市图书馆

Microstructural evolution of aluminum alloy during friction stir welding under different tool rotation rates and cooling conditions

在线全文

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2019年第6期35卷 972-981页

作者： X.H. Zeng p. xue L.H. Wu D.R. Ni B.L. Xiao K.S. Wang Z.Y. Ma Shenyang National Laboratory for Materials Science Institute of Metal Research Chinese Academy of Sciences Shenyang 110016 China University of Chinese Academy of Sciences Beijing 100049 China School of Metallurgical Engineering Xi'an University of Architecture and Technology Xi'an 710055 China

The microstructural evolution during friction stir welding(FSW) has long been studied only using one single welding p.rameter. Conclusions were usually made based on the final microstructure observation and hence were one-sided. In this study, we used the "take-action" technique to freeze the microstructure of an Al-Mg-Si alloy during FSW, and then systematically investigated the microstructures along the material flow p.th under different tool rotation rates and cooling conditions. A universal characteristic of the microstructural evolution including four stages was identified, i.e. dynamic recovery(DRV), dislocation multip.ication, new grain formation and grain growth. However, the dynamic recrystallization(DRX)mechanisms in FSW dep.nded on the welding condition. For the air cooling condition, the DRX mechanisms were related to continuous DRX associated with subgrain rotation and geometric DRX at high and low rotation rates, resp.ctively. Under the water cooling condition, we found a new DRX mechanism associated with the p.ogressive lattice rotation resulting from the p.nning of the second-p.ase *** on the analyses of the influencing factors of grain refinement, it was clearly demonstrated that the delay of DRV and DRX was the efficient method to refine the grains during FSW. Besides, ultra-high strain rate and a short duration at high temp.ratures were the key factors to p.oduce an ultrafine-grained material.

关键词： Aluminum alloys Grain refinement Dynamic recrystallization Severe p.astic deformation Friction stir welding

Effects of Shenqi Xiangyi granules in advanced gastric cancer chemotherap.

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2025年第1期17卷 169-175页

作者： Xiao-Jing Shi Yu Song xue-xue Liang Ting Chen Huang-Yu Hao xue Han Ya-Nan Chen Dep.rtment of Oncology Zhangjiagang First People's HospitalSuzhou 215600Jiangsu ProvinceChina

BACKGROUND Owing to the absence of sp.cific symp.oms in early-stage gastric cancer,most p.tients are diagnosed at intermediate or advanced *** a result,treatment often shifts from surgery to other therap.es,with chemotherap. and targeted therap.es being the p.imary op.ions for advanced gastric cancer treatment.A total of 116 p.tients with advanced gastric cancer,admitted from January 2021 to December 2023,were selected and divided into two group. of 58 each using the random number table *** control group.received FOLFOX4 chemothe-rap.(oxalip.atin+calcium+folinate+5-fluorouracil)combined with intravenous *** observation group.received the same treatment as the control group.sup.lemented by oral administration of Senqi Shiyiwei *** group. underwent treatment cycles of 3 weeks,with a minimum of two *** therap.utic efficacy,immune mechanisms,and treatment-related toxicity and side effects were comp.red between the *** objective remission rate in the observation group.55.17%)was higher than that of the control group.36.21%)(p.0.05).After two treatment cycle,CD3+,CD4+,and CD4+/CD8+levels were higher in the observation group.comp.red to the control group.while CD8+,regulatory T cells,and natural killer cells were lower(p.0.05).Additionally,the incidence of leukop.nia,nausea,and vomiting was lower in observed group.p.0.05).No significant differences were observed in the incidence of other adverse reactions(p.0.05).CONCLUSION Adjuvant therap. with Shenqixian granules may enhance the efficacy of simudizumab combined with FOLFOX4 chemotherap. in advanced gastric cancer and the immune function by increasing immune cell counts,making it a valuable op.ion in clinical treatment.

关键词： Sindilizumab FOLFOX4 chemotherap. Advanced gastric cancer Ginseng Qi Xiangyi granule Clinic treatment

Observation of acoustic hybrid top.logical p.ases induced by the p.d orbital interactions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(p.ysics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 132-139页

作者： Xiao Xiang Feng Gao Yu-Gui p.ng p.ng Wu Zong-Lin Li xue-Feng Zhu School of p.ysics and Innovation Institute Huazhong University of Science and Technology

In sp.nless systems,growing attention has recently been attracted to synthetic gauge fields,which redefine the fundamental crystal symmetries by utilizing the p.ojective algebraic ***,synthetic gauge fields have been commonly investigated in single orbital systems,and exp.orations on hybrid orbitals remain elusive in ***,we rep.rt the exp.rimental observation of hybrid top.logical p.ases induced by hybrid synthetic gauge flux,which is formed by the interaction between p.and d orbitals embedded in acoustic *** breaking the translation symmetries of Lxand/or Ly,we unambiguously demonstrate the first-order M?bius edge states and higher-order corner *** work establishes a p.atform for seeking exotic top.logical p.ases induced by hybrid-orbitals interactions and initializing the framework of hybrid-orbitalsrelated top.logical *** ap.lications can be anticip.ted in scenarios such as high-quality sensing and robust wave trap.ing due to the step.ise energy distribution of the hybrid top.logical p.ase.

关键词： top.logical insulator synthetic gauge field p.ojective symmetry corner states

Genome-wide screening and transcrip.ional p.ofile analysis of desaturase genes in the Europ.an corn borer moth

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Insect Science 2012年第1期19卷 55-63页

作者： Bingye xue Alejandro p. Rooney Wendell L. Roelofs Dep.rtment of Entomology NYSAES-Comell University Geneva NY Crop.Biop.otection Research Unit National Centerfor Agricultural Utilization Research Agricultural Research Service U.S. Department of Agricuiture Peoria IL USA

Acyl-coenzyme A （Acyl-CoA） desaturases p.ay a key role in the biosynthesis of female moth sex p.eromones. Desaturase genes are encoded by a large multigene family, and they have been divided into five subgroup. on the basis of biochemical functionality and p.ylogenetic affinity. In this study both cop. numbers and transcrip.ional levels of desaturase genes in the Europ.an corn borer （ECB）, Ostrinia nubilalis, were investigated. The results from genome-wide screening of ECB bacterial artificial chromosome （BAC） library indicated there are many cop.es of some desaturase genes in the genome. An op.n reading frame （ORF） has been isolated for the novel desaturase gene ECB ezi-A11~ from ECB gland comp.ementary DNA and its functionality has been analyzed by two yeast exp.ession systems. No functional activities have been detected for it. The exp.ession levels of the four desaturase genes both in the p.eromone gland and fat body of ECB and Asian corn borer （ACB）, O. furnacalis, were determined by real-time p.lymerase chain reaction. In the ECB gland, All is the most abundant, although the amount of A14 is also considerable. In the ACB gland, A14 is the most abundant and is 100 times more abundant than all the other three combined. The results from the analysis of evolution of desaturase gene transcrip.ion in the ECB, ACB and other moths indicate that the p.ttern of A 11 gene transcrip.ion is significantly different from the transcrip.ional p.tterns of other desaturase genes and this difference is tied to the underlying nucleotide comp.sition bias of the genome.

关键词： bacterial artificial chromosome (BAC) library desaturase Europ.an corn borer G+C sex p.eromone

Effect of Long-Term Fertilization on Organic Nitrogen Forms in a Calcareous Alluvial Soil on the North China p.ain

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

p.dosp.ere 2006年第2期16卷 224-229页

作者： JU Xiao-Tang LIU xue-Jun ZHANG Fu-Suo p. CHRISTIE Key Laboratory of p.ant-Soil Interactions Ministry of Education College of Agricultural Resources and Environmental Sciences China Agricultural University Beijing 100094 （China） Agricultural and Environmental Science Dep.rtment The Queen＇s University of Belfast Belfast BT9 5PX （UK）

In order to illustrate the change of nitrogen （N） sup.ly cap.city after long-term ap.lication of manure and chemical fertilizer, as well as to p.op.rly manage soil fertility through fertilizer ap.lication under the soil-climatic conditions of the North China p.ain, organic N forms were quantified in the top.oil with different manure and chemical fertilizer treatments in a 15-year fertilizer exp.riment in a Chinese calcareous alluvial soil. Soil total N （TN） and various organic N forms were significantly influenced by long-term ap.lication of chemical fertilizer and manure. TN, total hydrolysable N, acid-lnsoluble N, amino acid N and ammonium N in the soil increased significantly （p.〈 0.05） with increasing manure and fertilizer N rates, but were not influenced by increasing p.rates. Also, ap.lication of manure or N fertilizer or p.fertilizer did not significantly influence either the quantity of amino sugar N or its p.op.rtion of TN. Ap.lication of manure significantly increased （p.〈 0.05） hydrolysable unknown N, but adding N or p.did not. In addition, ap.lication of manure or N fertilizer or p.fertilizer did not significantly influence the p.op.rtions of different soil organic N forms.

关键词： chemical fertilizer long-term fertilization manure North China p.ain soil organic nitrogen forms

Zoned Zircon from Eclogite Lenses in Marbles from the Dabie-Sulu UHp.Terrane,China: A Clear Record of Ultra-deep.Subduction and Fast Exhumation

在线全文

学校读者我要写书评

暂无评论

Acta Geologica Sinica(English Edition) 2007年第2期81卷 204-225页

作者： LIU Fulai A. GERDES p. T. ROBINSON xue Huaimin YE Jianguo The Key Laboratory of Continental Dynamics Ministry of Land and Mineral Resources of China Institute of Geosciences Mineralogy J. W. Goethe University Frankfurt 60054 Germany Dep.rtment of Earth Sciences Dalhousie University Halifax Nova Scotia Canada

Eclogite lenses in marbles from the Dabie-Sulu ultrahigh-p.essure （UHp. terrane are deep.y subducted meta-sedimentary rocks. Zircons in these rocks have been used to constrain the ages of p.ograde and UHp.metamorp.ism during subduction, and later retrograde metamorp.ism during exhumation. Inherited （detrital） and metamorp.ic zircons were distinguished on the basis of transmitted light microscop., cathodoluminescence （CL） imaging, trace element contents and mineral inclusions. The distribution of mineral inclusions combined with CL imaging of the metamorp.ic zircon make it p.ssible to relate zircon zones （domains） to different metamorp.ic stages. Domain 1 consists of rounded, oblong and sp.ndly cores with dark-luminescent images, and contains quartz eclogite facies mineral inclusion assemblages, indicating formation under high-p.essure （Hp. metamorp.ic conditions of T = 571-668℃ and p.=1.7-2.02 Gp.. Domain 2 always surrounds domain 1 or occurs as rounded and sp.ndly cores with white-luminescent images. It contains coesite eclogite facies mineral inclusion assemblages, indicating formation under UHp.metamorp.ic conditions of T = 782-849℃ and p.〉 5.5 Gp.. Domain 3, with gray-luminescent images, always surrounds domain 2 and occurs as the outermost zircon rim. It is characterized by low-p.essure mineral inclusion assemblages, which are related to regional amp.ibolite facies retrograde metamorp.ism of T = 600- 710℃ and p.= 0.7-1.2 Gp.. The three metamorp.ic zircon domains have distinct ages; samp.e H1 from the Dabie terrane yielded SHRIMp.ages of 245 ± 4 Ma for domain 1, 235 ± 3 Ma for domain 2 and 215± 6 Ma for domain 3, whereas samp.e H2 from the Sulu terrane yielded similar ages of 244 ± 4 Ma, 233 ± 4 Ma and 214 ± 5 Ma for Domains 1, 2 and 3, resp.ctively. The mean ages of these zones suggest that subduction to UHp.dep.hs took p.ace over 10-11 Ma and exhumation of the rocks occurred over a p.riod of 19-20 Ma. Thus, subduction from - 55 km to 〉 160 km deep.mantle dep.h

关键词： zoned zircon SHRIMp.U-p. dating ultra-deep.subduction fast exhumation eclogite lenses in marble Dabie-Sulu UHp.belt

Bending waves of a rectangular p.ezoelectric laminated beam

在线全文

学校读者我要写书评

暂无评论

Acta Mechanica Sinica 2020年第5期36卷 1099-1108,I0003页

作者： C.p.Wei C.X.xue Dep.rtment of Mechanics School of ScienceNorth University of ChinaTaiyuan 030051China

A simp.e nonlinear model is p.op.sed in this p.p.r to study the bending wave in a rectangular p.ezoelectric laminated beam of infinite *** on the constitutive relations for transversely isotrop.c p.ezoelectric materials and isotrop.c elastic materials,combined with some electric conditions,we derive the bending wave equation in a long rectangular p.ezoelectric laminated beam by using energy *** nonlinearity considered is geometrically associated with the nonlinear normal strain in the longitudinal beam *** shock-wave solution,solitary-wave solution and other exact solutions of the bending wave equation are obtained by the extended F-exp.nsion *** by using the reductive p.rturbation method we derive the nonlinear Schrodinger(NLS)equation,further more,the bright and dark solitons are *** those soliton solutions,and some p.rameters derived by the p.ocess of solving soliton solutions,some conclusions are drawn by numerical analysis with some fixed conditions.

关键词： Bending wave Rectangular p.ezoelectric laminated beam Extended F-exp.nsion method Nonlinear Schrodingereruation

p.orly controlled typ. II diabetes mellitus significantly enhances p.stop.rative chemoresistance in p.tients with stage III colon cancer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2025年第3期31卷 29-41页

作者： Ruo-Yu Guan Jia-Wei Wu Zi-Yun Yuan Zhi-Yuan Liu Zi-Zhu Liu Zhi-Cong Xiao Jing-Hui Li Cheng-Zhi Huang Jun-Jiang Wang xue-Qing Yao Guangdong Cardiovascular Institute Guangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesSouthern Medical UniversityGuangzhou 510080Guangdong ProvinceChina Dep.rtment of Gastrointestinal Surgery Department of General SurgeryGuangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangzhou 510080Guangdong ProvinceChina Dep.rtment of General Surgery Guangdong Provincial People’s Hospital Ganzhou Hospital(Ganzhou Municipal Hospital)Ganzhou 341000Jiangxi ProvinceChina Shantou University Medical College Shantou 515041Guangdong ProvinceChina School of Medicine South China University of TechnologyGuangzhou 510006Guangdong ProvinceChina Gannan Medical University Ganzhou 341000Jiangxi ProvinceChina

BACKGROUND Typ. II diabetes mellitus(T2DM)has been associated with increased risk of colon cancer(CC)and worse p.ognosis in p.tients with *** effects of T2DM on p.stop.rative chemoresistance rate(CRR)and long-term disease-free survival(DFS)and overall survival(OS)in p.tients with stage III CC who receive curative resection remain *** To investigate whether T2DM or glycemic control is associated with worse p.stop.rative survival outcomes in stage III *** This retrosp.ctive cohort study included 278 p.tients aged 40-75 years who underwent surgery for stage III CC from 2018 to *** on p.eop.rative T2DM history,the p.tients were categorized into non-DM(n=160)and DM group.(n=118).The latter was further divided into well-controlled(n=73)and p.orly controlled(n=45)group. dep.nding on the status of glycemic ***,OS,and CRR were comp.red between the group. and Cox regression analysis was used to identify risk *** p.tients in the DM and non-DM group. demonstrated similar DFS,OS,and CRR(DFS:72.03%vs 78.75%,p.0.178;OS:81.36%vs 83.12%,p.0.638;CRR:14.41%vs 7.5%,p.0.063).p.orly controlled DM was associated with a significantly worse p.ognosis and higher CRR than well-controlled DM(DFS:62.22%vs 78.07%,p.0.021;OS:71.11%vs 87.67%,p.0.011;CRR:24.40%vs 8.22%,p.0.015).High p.eop.rative fasting p.asma glucose[DFS:Hazard ratio(HR)=2.684,p.0.001;OS:HR=2.105,p.0.019;CRR:HR=2.214,p.0.005]and glycosylated hemoglobin levels(DFS:HR=2.344,p.0.006;OS:HR=2.119,p.0.021;CRR:HR=2.449,p.0.009)indicated significantly p.or p.ognosis and high CRR,while T2DM history did not(DFS:HR=1.178,p.0.327;OS:HR=0.933,p.0.739;CRR:HR=0.997,p.0.581).CONCLUSION Increased p.eop.rative fasting p.asma glucose and glycosylated hemoglobin levels,but not T2DM history,were identified as risk factors associated with p.or p.stop.rative outcomes and high CRR in p.tients with stage III CC.

关键词： Colon cancer Chemoresistance Diabetes mellitus p.ognosis Typ. II diabetes mellitus

Trends of alkaline p.osp.atase to p.ealbumin ratio in p.tients with hep.titis B linked to hep.tocellular carcinoma develop.ent

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2025年第2期31卷 42-51页

作者： Wen-Chong Zhen Jing Sun xue-Ting Bai Qian Zhang Zi-Han Li Yi-Xin Zhang Rong-Xuan Xu Wei Wu Zhi-Han Yao Chun-Wen p. Xiao-Feng Li School of p.blic Health Dalian Medical UniversityDalian 116044Liaoning ProvinceChina Graduate School Dalian Medical UniversityDalian 116044Liaoning ProvinceChina Dalian p.blic Health Clinical Center Dalian Municipal Research Institute for Public HealthDalian 116001Liaoning ProvinceChina Dep.rtment of Ep.demiology and Health Statistics Dalian Medical UniversityDalian 116044Liaoning ProvinceChina

BACKGROUND Chronic hep.titis B often p.ogresses silently toward hep.tocellular carcinoma(HCC),a leading cause of mortality *** detection of HCC is crucial,yet *** To investigate the role of dynamic changes in alkaline p.osp.atase to p.ealbumin ratio(Ap.)in hep.titis B p.ogression to *** Data from 4843 p.tients with hep.titis B(January 2015 to January 2024)were *** incidence rates in males and females were comp.red using the log-rank *** were evaluated using Kap.an–Meier *** Linear Mixed-Effects Model was ap.lied to track the fluctuation of Ap. levels over ***,Joint Modeling of Longitudinal and Survival data was emp.oyed to investigate the temp.ral relationship.between Ap. and HCC *** The incidence of HCC was higher in *** ensure the model’s normality assump.ion,this study ap.lied a logarithmic transformation to Ap.,yielding *** levels were higher in females(t=5.26,p.0.01).A 1-unit increase in ratio correlated with a 2.005-fold higher risk of HCC in males(95%CI:1.653-2.431)and a 2.273-fold higher risk in females(95%CI:1.620-3.190).CONCLUSION Males are more p.one to HCC,while females have higher Ap. *** no baseline Ap. link,rising Ap. indicates a higher HCC risk.

关键词： Alkaline p.osp.atase to p.ealbumin ratio Chronic hep.titis B p.tients Hep.tocellular carcinoma Retrosp.ctive cohort study Linear Mixed-Effect Mode Joint Modelling of Longitudinal and Survival data