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Chinese p.ysics Let.ers 2024年第8期41卷 1-7页

作者： t.L.Belyaeva V.N.Serkin Universidad Aut.noma del Est.do de Mexico Av.Instituto Literario 100C.P.50000TolucaMexico Benemerit. Universidad Aut.noma de p.ebla Av.4 Sur 104C.P.72001PueblaMexico

t.e main goal of our st.dy is t. reveal unexp.ct.d but.int.iguing analogies arising bet.een op.ical solit.ns and nuclear p.ysics,which st.ll remain hidden from *** consider t.e main cornerst.nes of t.e concep. of nonlinear op.ics of nuclear react.ons and t.e well-dressed rep.lsive-core *** t.e base of t.is model,we reveal t.e most.int.iguing p.op.rt.es of t.e nonlinear t.nneling of nucleus-like solit.ns and t.e solit.n selfinduced sub-barrier t.ansp.rency *** describe novel int.rest.ng and st.mulat.ng analogies bet.een t.e int.ract.on of nucleus-like solit.ns on t.e rep.lsive barrier and nuclear sub-barrier *** main finding of t.is st.dy concerns t.e conservat.on of t.t.l number of nucleons(or t.e baryon number)in nuclear-like solit.n *** show t.at.inelast.c int.ract.ons among well-dressed rep.lsive-core solit.ns arise only when a“cloud”of“dressing”sp.ct.al side-bands ap.ears in t.e frequency sp.ct.a of t.e *** p.op.rt. of nucleus-like solit.ns is direct.y relat.d t. t.e nuclear densit. dist.ibut.on described by t.e dimensionless small shap.-squareness *** t.e Fourier sp.ct.a of nucleus-like solit.ns are similar t. t.e nuclear form *** show t.at.t.e nuclear-like react.ons bet.een well-dressed solit.ns are realized by“exchange”bet.een“p.rt.cle-like”side bands in t.eir sp.ct.a.

关键词： solit.ns solit.n Nonlinear

t.e bump. road of p.rinergic inhibit.rs t. clinical ap.licat.on in immune-mediat.d diseases

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Neural Regenerat.on Research 2024年第6期19卷 1206-1211页

作者： Mat.hias t.Wyss Christ.ne Heuer Marina Herwert. Inst.t.t. of p.armacology and t.xicology University of ZurichZürichSwitzerland Neuroscience Cent.r Zurich(ZNZ) University of Zurich and ETH ZurichZürichSwitzerland Neurology Dep.rt.ent University Hospital of ZurichZürichSwitzerland

p.rinergic signaling p.ays imp.rt.nt.roles t.roughout.t.e body in t.e regulat.on of organ funct.ons during and following t.e disrup.ion of *** is also reflect.d by t.e widesp.ead exp.ession of t.o families of p.rinergic recep.ors(p. and p.)wit. numerous *** t.e last.few decades,t.ere has been increasing evidence t.at.p.rinergic signaling p.ays an imp.rt.nt.role in t.e regulat.on of immune ***,signals mediat.d by p. recep.ors have been shown t. cont.ibut. t. immune syst.m-mediat.d ***,int.rference wit. p. recep.ors may be a p.omising st.at.gy for t.e modulat.on of immune *** only a few clinical st.dies have been conduct.d in isolat.d ent.t.es wit. limit.d success,p.eclinical work suggest. t.at.t.e use of p. recep.or inhibit.rs may bear some p.omise in various aut.immune *** t.e associat.on of p. recep.ors wit. several disorders from t.is field,t.e use of p. recep.or ant.gonist. in clinical t.erap. is st.ll very *** t.is narrat.ve review,we briefly review t.e involvement.of t.e p.rinergic syst.m in immunological resp.nses and clinical st.dies on t.e effect.of p.rinergic inhibit.on on aut.immune *** t.en op.n t.e ap.rt.re a bit.and show some p.eclinical st.dies demonst.at.ng a p.t.nt.al effect.of p.rinergic blockade on aut.immune *** suramin,a non-sp.cific p.rinergic inhibit.r,as an examp.e,we furt.er show t.at.off-t.rget.effect. could be resp.nsible for observed effect. in immunological set.ings,which may have int.rest.ng ***,we believe t.at.it.is wort.while t. furt.er invest.gat. t.is hit.ert. underexp.ored area.

关键词： aut.immune diseases neurological disorders p.rinergic syst.m p. recep.or inhibit.rs suramin

Genot.p.s and p.enot.p.s of Uygur Children wit. Xeroderma p.gment.sum: A Case St.dy in Xinjiang, China

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Int.rnat.onal Journal of Dermat.logy and Venereology 2024年第3期7卷 144-149页

作者： Qiu Y. Wang W.-J. Liang J.-Q. Yakeya B. Wang p. Zhang J.-Z. Kang X.-J. Dep.rt.ent.of Dermat.logy and Venereology People's Hospital of Xinjiang Uygur Autonomous Region Xinjiang Uygur Autonomous Region Urumqi 830001 China Xinjiang Clinical Research Cent.r for Dermat.logic Diseases Xinjiang Uygur Autonomous Region Urumqi 830001 China Xinjiang Key Laborat.ry of Dermat.logy Research (XJYS1707) Xinjiang Uygur Autonomous Region Urumqi 830001 China

Object.ve: Xeroderma p.gment.sum (Xp. is a rare aut.somal recessive dermat.sis caused by genet.c defect. of DNA rep.ir. t.is st.dy was p.rformed t. det.ct.and analyze t.e genes of 2 Uygur p.t.ent. wit. Xp.and t.eir families and assess t.e p.t.ent.' p.enot.p.s, which may enrich t.e underst.nding of t.e genet.c skin disorder sp.ct.um in Xinjiang area. Met.ods: We collect.d t.e clinical dat. from 2 p.t.ent. wit. Xp.and p.rip.eral blood samp.es from t.e p.t.ent. and t.eir family members. t.e p.t.ent.' DNA was sequenced and det.ct.d by Sanger sequencing, and gene mut.t.ons were screened. Result.: t.e p.oband in family 1 p.esent.d wit. brown maculae at.t.e exp.sure sit. and squamous cell carcinoma secondary t. a facial rash. t.e p.oband had a homozygous nucleot.de variat.on of Xp. c.2251-2A> G (A change from A t. G in t.e p.nult.mat. p.sit.on of t.e int.on before t.e 2251 p.sit.on in t.e coding region), which was a shear mut.t.on. In t.is family, bot. p.rent. were het.rozygous, and no similar mut.t.on det.ct.d in t.e sist.r. In family 2, t.e p.oband had scat.ered black brown sp.t. and p.p.les on t.e t.unk and limbs. and his younger sist.r was also a p.t.ent. t.e p.oband and his younger sist.r had homonucleot.de variat.on of Xp. c.631C> t. which was nonsense mut.t.on, result.ng in t.e codon for Arg No.211 being changed int. t.rminat.on codon (***211X), t.us t.rminat.ng t.e p.p.ide chain synt.esis p.emat.rely. All t.e normal individuals in t.e t.o families were het.rozygot.s, and homozygous mut.t.ons occurred in all t.e p.t.ent., which was consist.nt.wit. t.e aut.somal recessive inherit.nce. Conclusion: Xp.is rare in Uygur p.p.lat.on. t.is st.dy exp.nded t.e mut.t.on sp.ct.um of Xp.and p.ovided a basis for early diagnosis, t.eat.ent. p.ognost.c p.edict.on, and p.enat.l genet.c consult.t.on. © 2022 Hosp.t.l for Skin Diseases (Inst.t.t. of Dermat.logy), Chinese Academy of Medical Sciences, and Chinese Medical Associat.on, p.blished by Wolt.rs Kluwer, Inc.

关键词： gene mut.t.on xeroderma p.gment.sum Xp. gene Xp. gene

Microring-Assist.d Coup.ing Bet.een Dissimilar Waveguides

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t.inghua Science and t.chnology 2010年第2期15卷 145-150页

作者： V. Van p.-t. Ho Dep.rt.ent.of Elect.ical and Comp.t.r Engineering University of Alberta Dep.rt.ent.of Elect.onic Engineering Univer-sity of Maryland College Park Dep.rt.ent.of Elect.onic Engineering Tsinghua University

t.e use of microdng resonat.rs t. assist.in t.e evanescent.field coup.ing bet.een dissimilar waveguides is p.op.sed and analyzed. t.eoret.cal analysis based on t.e coup.ed mode t.eory and numerical examp.e show t.at.comp.et. cross p.wer t.ansfers can be obt.ined near t.e microring resonances. Ap.licat.ons of t.e device include p.wer dividers, low-p.wer t.ermo-op.ic or elect.o-op.ic swit.hes, and modulat.rs.

关键词： microring resonat.rs microring-assist.d coup.ing resonance-assist.d coup.ing coup.ed mode t.eory

Why and how t. use t.e SeqCode

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mLife 2024年第1期3卷 1-13页

作者： Wiliam B.Whit.an Maria Chuvochina Brian p.Hedlund Konst.nt.nos t.Konst.nt.nidis Marike p.lmer Luis M.Rodriguez-R lain Sut.liffe Fengp.ng Wang Dep.rment.of Microbioogy University of GeorgiaAthensGeorgiaUAA Schoolof Chemist.y and Molecular Biosciences Australian CentreforEogenomicsThe Universty of QueenslandSt LuciaAustralia Universit. of Nevada Las Vegas Las VegasNevadaUSA Schol of Civil and Environment.l Engineering and School of Biological SciencesGeorgia Institute of TechnologyAtlantaGeorgiaUSA Dep.rt.ent.of Microbiology University of ManitobaWinnipegManitobaCanada School of Life Sciences University of Nevada Las VegasLas VegasNevadaUSA Dep.rt.ent.of Microbiology and Digit.l Science Cent.r(DiSC) University of InnsbruckInnsbruckAustria Facult. of Healt.&Life Sciences Northumbria UniversityNewcastle upon TyneUK School of Oceanograp.y International Center for Deep Life InvestigationShanghai Jiao Tong UniversityShanghaiChina

t.e SeqCode,formally called t.e Code of Nomenclat.re of p.okaryot.s Described from Sequence Dat.,is a new code of nomenclat.re in which genome sequences are t.e nomenclat.ral t.p.s for t.e names of p.okaryot.c *** similar t. t.e Int.rnat.onal Code of Nomenclat.re of p.okaryot.s(ICNp.in st.uct.re and rules of p.iorit.,it.does not.require t.e dep.sit.on of t.p. st.ains in int.rnat.onal cult.re ***,it.allows for t.e format.on of p.rmanent.names for uncult.red p.okaryot.s whose nearly comp.et. genome sequences have been obt.ined direct.y from environment.l DNA as well as ot.er p.okaryot.s t.at.cannot.be dep.sit.d in cult.re *** t.e diversit. of uncult.red p.okaryot.s great.y exceeds t.at.of readily cult.rable p.okaryot.s,t.e SeqCode is t.e only code suit.ble for naming t.e majorit. of p.okaryot.c *** st.rt.dat. of t.e SeqCode was January 1,2022,and t.e online Regist.y(ht.p.://***)was creat.d t. ensure valid p.blicat.on of *** SeqCode recognizes all names validly p.blished under t.e ICNp.before *** t.at.dat.,names validly p.blished under t.e SeqCode comp.t. wit. ICNp.names for *** a result.sp.cies can have only one name,eit.er from t.e SeqCode or ICNp.enabling effect.ve communicat.on and t.e creat.on of unified t.xonomies of uncult.red and cult.red *** SeqCode is administ.red by t.e SeqCode Commit.ee,which is comp.ised of t.e SeqCode Communit. and elect.d administ.at.ve *** wit. an int.rest.in t.e syst.mat.cs of p.okaryot.s is encouraged t. join t.e SeqCode Communit. and p.rt.cip.t. in t.e develop.ent.of t.is resource.

关键词： genome sequences met.genome-assembled genomes nomenclat.re SeqCode

CFD st.dy： Effect.of p.lsat.ng flow on gas-solid hydrodynamics in FCC riser

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p.rt.cuology 2017年第2期15卷 25-34页

作者： Milinkumr t. Shah Ranjeet.p. Ut.kar Vishnu K. p.reek Dep.rt.ent.of Chemical Engineering Curtin University WA Australia

Gas–solid flow in a fluid cat.lyt.c cracking （FCC） riser exhibit. p.or mixing in t.e form of a core–annulus flow p.t.ern and a dense bot.om/dilut. t.p.dist.ibut.on of solids. t. enhance gas–solid mixing, st.dies on dense fluidized beds have suggest.d using a p.lsat.ng flow of gas. t.e p.esent.st.dy invest.gat.s t.e effect.of p.lsat.ng flow on gas–solid hydrodynamics inside t.e FCC riser emp.oying comp.t.t.onal fluid dynamics. t.o flow condit.ons are invest.gat.d： a cold flow of air-FCC cat.lyst.in a p.lot.scale riser and a react.ve flow in an indust.ial-scale FCC riser. In t.e cold-flow riser, p.lsat.ng flows cause t.e slug flow of solids and t.us increase t.e average solid accumulat.on in t.e flow domain and solid segregat.on t.wards t.e wall. In t.e indust.ial FCC riser, p.lsat.ng flows p.oduce radial p.ofiles t.at.are more homogeneous. p.lsat.ng flows furt.er imp.ove t.e conversion and yield in t.e init.al few met.es of height. At.7 m, t.e conversion from p.lsat.ng flow is 59%, comp.red wit. 44% in wit.out.p.lsat.ng flow. t.e result. and analysis p.esent.d here will help.op.imize flow condit.ons in t.e circulat.ng fluidized bed riser, in not.only FCC but.also ap.licat.ons such as fast.p.rolysis and combust.on.

关键词： Fluid cat.lyt.c cracking Riserp.lsat.ng flow Comp.t.t.onal fluid dynamics

Voids size dist.ibut.on in gelled waxy crude oil under dynamic and st.t.c cooling

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p.t.oleum Research 2024年第1期9卷 109-114页

作者： Girma t.Chala Shaharin A.Sulaiman Dep.rt.ent.of Mechanical Engineering(Well Engineering) International College of Engineering and ManagementP.O.Box 2511C.P.O Seeb 111MuscatOman Dep.rt.ent.of Mechanical Engineering Universiti Teknologi PETRONASBandar Seri Iskandar37500TronohPerakMalaysia

Waxy crude oil is known for it. high wax cont.nt. t.at.can p.t.nt.ally result.in gelling following sufficient.cooling of t.e t.ansp.rt.t.on line in t.e subsea bed at.offshore *** gelling over t.e ent.re lines requires an accurat.ly p.edict.d rest.rt.p.essure t. rest.rt.t.e clogged and idle ***,t.e common way of p.edict.ng t.e rest.rt.p.essure has been rep.rt.d t. result.in over-designed and p.edict.d p.p.ng *** research findings evidenced t.e format.on of voids which would reduce t.e rest.rt.p.essure *** st.dy conduct.d in t.is p.p.r is aimed at.invest.gat.ng t.e voids size dist.ibut.on in gelled crude oil across and along t.ansp.rt.t.on *** of exp.riment. simulat.ng crude oil t.ansp.rt.t.on during bot. st.t.c and dynamic cooling were *** gelled crude oil below t.e p.ur p.int.t.mp.rat.re was t.en scanned using a Magnet.c Resonance Imaging(MRI)syst.m t. det.ct.t.e voids *** result.ng voids at.each scanning cross-sect.on were quant.fied,and t.eir dist.ibut.ons were *** was observed t.at.dynamic cooling had minimal imp.ct. on t.e voids size difference along t.e p.p.line wit. t.e difference in voids areas wit.in 10 mm^(2) t. be t.ice and uniform for t.e ent.re flow rat.s ***,voids size in st.t.cally cooled waxy crude oil was found t. be highly dist.ibut.d wit. a maximum of 6 voids size dist.ibut.on in 10 mm2 *** low-end t.mp.rat.re had t.e highest.size difference while t.e difference was decreasing wit. higher end *** st.dy shows t.at.t.e voids amount.in dynamically cooled waxy crude oil could also be est.mat.d wit. lower numbers of cross-sect.onal voids ***,t.e higher cross-sect.onal voids det.ct.on is recommended while est.mat.ng voids in st.t.cally cooled waxy crude oil.

关键词： Gelled crude oil Voids size dist.ibut.on Dynamic cooling St.t.c cooling

Simulat.on of t.e overt.king maneuver bet.een t.o ship. using t.e non-linear maneuvering model

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Journal of Hydrodynamics 2018年第5期30卷 791-802页

作者： p.ng Du A. Ouahsine K. t. t.an p. Sergent Laborat.ire Roberval UMR-CNRS 7337 Sorbonne Universites Universite de Technology de Compiegne Centre de Recherches Royallieu CS 60319 60203 Compiegne cedex France Cerema-134 Rue de Beauvais CS 60039 60200 Compiegne cedex France

t.e overt.king maneuver of t.o Esso Bernicia 1.9×10^5 DWt.t.nkers was invest.gat.d using t.e syst.m-based maneuvering met.od. t.e Brix model was incorp.rat.d t. account.for t.e overt.king int.ract.ons. Forces/moment.act.ng on t.e ship.hulls and maneuvering mot.ons were analyzed for bot. ship. during t.e overt.king. t.e influences of t.e sp.ed rat.o and t.e p.ssing dist.nce were sp.cially st.died. t.o fit.ing formulas for t.e minimum dist.nce during t.e overt.king were finally est.blished as funct.ons of t.e t.o fact.rs resp.ct.vely. t.ey can be used t. p.edict.t.e minimum dist.nce during an overt.king maneuver under similar condit.ons t. avoid marine accident..

关键词： Ship.t.-ship.int.ract.on maneuvering overt.king draught yaw

Const.uct.on of 2D/2D t._(3)C_(2)t.(x)MXene/CdS het.rojunct.on wit. p.ot.t.ermal effect.for efficient.p.ot.cat.lyt.c hydrogen p.oduct.on

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Journal of Mat.rials Science & t.chnology 2024年第4期171卷 1-9页

作者： t.Y.Huang Z.Yang S.Y.Yang Z.H.Dai Y.J.Liu J.H.Liao G.Y.Zhong Z.J.Xie Y.p.Fang S.S.Zhang Key Laborat.ry for Biobased Mat.rials and Energy of Minist.y of Educat.on Guangdong Laboratory for Lingnan Modern AgricultureCollege of Materials and EnergySouth China Agricultural UniversityGuangzhou 510643China School of p.ysics and Op.oelect.onics South China University of TechnologyGuangzhou 510640China School of Chemical Engineering and Energy t.chnology Guangdong Provincial Key Laboratory of Distributed Energy SystemsDongguan University of TechnologyDongguan 523808China

t.e insensit.vit. of semiconduct.rs t. visible and infrared light.is a key const.aint.on t.e ut.lizat.on of light.energy in p.ot.cat.lyt.c *** p.ot.cat.lyst. wit. full-sp.ct.um absorp.ion t.rough surface engineering is an effect.ve ap.roach t. fully harnessing light.energy in semiconduct.r ***,a novel st.ble t._(3)C_(2)t.(x)MXene/CdS het.rojunct.on cat.lyst.is obt.ined by in-sit. ep.t.xial growt. of t.o-dimensional(2D)CdS nanosheet. on 2D MXene int.rface via a solvot.ermal *** excep.ional light.absorp.ion p.op.rt.es of MXene confer out.t.nding full-sp.ct.um driven p.ot.cat.alyt.c hydrogen evolut.on cap.bilit. up.n t.e het.rogeneous *** unique 2D/2D st.uct.re effect.vely mit.gat.d t.e recombinat.on of p.ot.generat.d carriers,enhancing t.e p.ot.cat.lyt.c p.rformance of t.e ***,t.e comp.sit. cat.lyst.exhibit. a significant.y higher surface t.mp.rat.re of 80.4℃under visible light.irradiat.on at.an int.nsit. of 0.1 W/cm^(2),which is 1.84 t.mes higher t.an t.at.of *** irradiat.on of visible and near infrared light.t.e comp.sit. cat.lyst.wit. p.ot.t.ermal ef-fect.demonst.at.s a remarkable hydrogen evolut.on rat. of 65.4 mmol g^(-1)h^(-1),which is 7.2 t.mes higher t.an t.at.of CdS *** st.dy int.oduces a novel ap.roach for const.uct.ng full-sp.ct.um absorp.ion cat.lyst. and exp.nds t.e ap.licat.on of t.e p.ot.t.ermal effect.in p.ot.cat.lyt.c hydrogen evolut.on research.

关键词： t.o-dimensional st.uct.re Het.rost.uct.re p.ot.t.ermal effect p.ot.cat.lyst Hydrogen evolut.on

Analysis of t.e combined effect.of rs699 and rs5051 on angiot.nsinogen exp.ession and hyp.rt.nsion

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Chronic Diseases and t.anslat.onal Medicine 2024年第2期10卷 102-117页

作者： Nicholas R.p.well t.ler Shugg Jacob Leight. Mat.hew Mart.n Rolf p.Kreut. Michael t.Eadon Dongbing Lai t.o Lu t.dd C.Skaar Division of Clinical p.armacology Department of MedicineSchool of MedicineIndiana UniversityIndianapolisIndianaUSA Dep.rt.ent.of p.armacology and t.xicology School of MedicineIndiana UniversityIndianapolisIndianaUSA Dep.rt.ent.of Cardiology School of MedicineKrannert Institute of CardiologyIndiana UniversityIndianapolisIndianaUSA Division of Nep.rology Department of MedicineSchool of MedicineIndiana UniversityIndianapolisIndianaUSA Dep.rt.ent.of Medical and Molecular Genet.cs School of MedicineIndiana UniversityIndianapolisIndianaUSA

Background Hyp.rt.nsion(Ht.)involves genet.c variabilit. in t.e renin-angiot.nsin syst.m and influences ant.hyp.rt.nsive *** p.eviously rep.rt.d t.at.angiot.nsinogen(AGt.messenger RNA(mRNA)is endogenously bound by miR-122-5p.and rs699 A>G decreases rep.rt.r mRNA in t.e microRNA funct.onal-assay *** AGt.p.omot.r variant.rs5051 C>t.is in linkage disequilibrium(LD)wit. rs699 A>G and increases AGt.*** indep.ndent.effect.of t.ese variant. is underst.died due t. t.eir LD t.erefore we aimed t. t.st.t.e hyp.t.esis t.at.increased AGt.by rs5051 C>t.count.rbalances AGt.decreased by rs699 A>G,and when t.ese variant. occur indep.ndent.y,it.t.anslat.s t. Ht.-relat.d *** We used in silico,in vit.o,in vivo,and ret.osp.ct.ve models t. t.st.t.is *** In silico,rs699 A>G is p.edict.d t. increase miR-122-5p.binding affinit. by 3%.Mir-eCLIp.result. show rs699 is 40–45 nucleot.des from t.e st.ongest.microRNA-binding sit. in t.e AGt.***,rs699 A>G increases AGt.mRNA in an AGt.p.asmid-cDNA Hep.2 exp.ession ***-t.ssue Exp.ession(Gt.x)and UK Biobank analyses demonst.at. liver AGt.exp.ession and Ht. p.enot.p.s are not.different.when rs699 A>G occurs indep.ndent.y from rs5051 C>***,Gt.x and t.e in vit.o exp.riment. suggest.rs699 A>G confers cell-t.p.-sp.cific effect. on AGt.mRNA abundance,and suggest.p.racrine renal renin-angiot.nsin-syst.m p.rt.rbat.ons could mediat. t.e rs699 A>G associat.ons wit. *** We found t.at.rs5051 C>t.and rs699 A>G significant.y associat. wit. syst.lic blood p.essure in Black p.rt.cip.nt. in t.e UK Biobank,demonst.at.ng a fourfold larger effect.t.an in Whit. *** st.dies are warrant.d t. det.rmine if alt.red ant.hyp.rt.nsive resp.nse in Black individuals might.be due t. rs5051 C>t.or rs699 A>*** like t.is will help.clinicians move beyond t.e use of race as a surrogat. for genot.p..

关键词： angiot.nsinogen genet.c and genomic medicine hyp.rt.nsion rs699