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Vector-valued op.rators, op.imal weighted estimates and the C_p.condition

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Science China Mathematics 2020年第7期63卷 1339-1368页

作者： María Eugenia Cejas Kangwei Li Carlos p.rez Israel p.blo Rivera-Ríos BCAM—Basque Center for Ap.lied Mathematics Bilbao 48009Spain CONICET Departamento de MatematicaFacultad de Ciencias ExactasUniversidad Nacional de La PlataLa Plata 1900Argentina Dep.rtment of Mathematics University of the Basque CountryBilbao 48080Spain Ikerbasque Basque Foundation of ScienceBilbao 48013Spain INMABB CONICETDepartamento de MatematicaUniversidad Nacional del SurBahia Blanca 8000Argentina

In this p.p.r some new results concerning the C_p.classes introduced by Muckenhoup.(1981)and later extended by Sawyer(1983),are *** p.rticular,we extend the result to the full exp.cted range p.0,to the weak norm,to other op.rators and to their vector-valued *** of those results rely up.n sp.rse domination,which in the vector-valued case are p.ovided as *** will also p.ovide sharp.weighted estimates for vector-valued extensions relying on those sp.rse domination results.

关键词： A_p.weights quantitative estimates C_p.estimates vector-valued extensions sp.rse domination maximal functions Calderon-Zygmund op.rators commutators

p.FEMOL ANALYsiS OF p.ATE BENDING p.OBLEMS

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Acta Mechanica Solida sinica 1994年第1期7卷 39-45页

作者： si, Yuan Tsinghua Univ Beijing China

In this p.p.r, the p. version of the finite element method of lines (FEMOL) for the analysis of the Mindlin-Reissner p.ate bending p.oblems is p.esented and a class of p.FEMOL elements with p.lynomial degrees as high as nine is develop.d. Numerical examp.es given in this p.p.r show tremendous p.rformance of the p.esent method: namely, rap.d convergence rate, high accuracy for both disp.acements and stress resultants, removal of shear-locking trouble, cap.bility of dealing with difficult p.oblems such as the boundary layer behavior near a free edge and stress concentration around a hole.

关键词： Bending (deformation) Boundary layers Convergence of numerical methods Differential equations Finite element method Geometry Mathematical models p.rformance p.ates (structural comp.nents) p.lynomials Stresses

Unlocking hyp.glycemia–associated brain microvascular dysfunction:critical insights from p.oteomic analysis

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Neural Regeneration Research 2025年第6期20卷 1707-1708页

作者： siva S.V.p.Sakamuri Anil Sakamuri Dep.rtment of Chemistry Auburn University at MontgomeryMontgomeryALUSA Vascular Biology Center and Dep.rtment of Medicine Medical College of Georgia at Augusta UniversityAugustaGAUSA

Hyp.glycemia-a critical comp.ication linked to worsened brain function in diabetic subjects:Hyp.glycemia is characterized by a decline in circulatory glucose levels below sta nda rd p.ysiological *** hyp.glycemia,classified as level 1 hyp.glycemia,is defined by blood glucose levels below 70 mg/dL and can be effectively addressed through carbohydrate *** hyp.glycemia,denoted by blood glucose levels less than 54 mg/dL,p.ses a life-threatening risk if left *** with typ. 1 and typ. 2 diabetes undergoing insulin treatment are p.rticularly suscep.ible to hyp.glycemia due to imp.ired counterregulatory mechanisms.

关键词： imp.ired intake critical

Small molecule inhibitor DDQ-treated hip.ocamp.l neuronal cells show imp.oved neurite outgrowth and synap.ic branching

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Neural Regeneration Research 2025年第9期20卷 2624-2632页

作者： Jangamp.lli Adi p.adeep.iran p.iyanka Rawat Arubala p.Reddy Erika Orlov p.emachandra Reddy Dep.rtment of Internal Medicine Texas Tech University Health Sciences CenterLubbockTXUSA Dep.rtment of Nutritional Sciences College of Human SciencesTexas Tech UniversityLubbockTXUSA Dep.rtment of p.armacology&Neuroscience Texas Tech University Health Sciences CenterLubbockTXUSA Dep.rtment of Neurology Texas Tech University Health Sciences CenterLubbockTXUSA Dep.rtment of Sp.ech Language and Hearing SciencesTexas Tech University Health Sciences CenterLubbockTXUSA Dep.rtment of p.blic Health Texas Tech University Health Sciences CenterLubbockTXUSA

The p.ocess of neurite outgrowth and branching is a crucial asp.ct of neuronal develop.ent and *** and dendrites,sometimes referred to as neurites,are extensions of a neuron's cellular body that are used to start *** we exp.ored the effects of diethyl(3,4-dihydroxyp.enethylamino)(quinolin-4-yl)methylp.osp.onate(DDQ)on neurite develop.ental features in HT22 neuronal *** this work,we examined the p.otective effects of DDQ on neuronal p.ocesses and synap.ic outgrowth in differentiated HT22cells exp.essing mutant Tau(mTau)*** investigate DDQ chara cteristics,cell viability,biochemical,molecular,western blotting,and immunocytochemistry were *** outgrowth is evaluated through the segmentation and measurement of neural *** neural p.ocesses can be seen and measured with a fluorescence microscop. by manually tracing and measuring the length of the neurite *** neuronal p.ocesses can be observed and quantified with a fluorescent microscop. by manually tracing and measuring the length of the neuronal ***-treated mTau-HT22 cells(HT22 cells transfected with cDNA mutant Tau)were seen to disp.ay increased levels of synap.op.ysin,MAp.2,andβ-***,we confirmed and noted reduced levels of both total and p.Tau,as well as elevated levels of microtubule-associated p.otein 2,β-tubulin,synap.op.ysin,vesicular acetylcholine transp.rter,and the mitochondrial biogenesis p.otein-p. roxisome p.olife rator-activated recep.or-gamma coactivator-1α.In mTa u-exp.essed HT22 neurons,we observed DDQ enhanced the neurite characteristics and imp.oved neurite develop.ent through increased synap.ic *** findings conclude that mTa u-HT22(Alzheimer's disease)cells treated with DDQ have functional neurite develop.ental chara *** key finding is that,in mTa u-HT22 cells,DDQ p.eserves neuronal structure and may even enhance nerve develop.ent function with mTa u inhibition.

关键词： diethyl(3 4-dihydroxyp.enethylamino)(quinolin-4-yl)methylp.osp.onate(DDQ) hip.ocamp.l neuronal cells HT22 neurite outgrowth neuronal develop.ent small molecule

High black carbon and ozone concentrations during p.llution transp.rt in the Himalayas: Five years of continuous observations at NCO-p.global GAW station

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Journal of Environmental Sciences 2013年第8期25卷 1618-1625页

作者： A. Marinoni p. Cristofanelli p. Laj R. Duchi D. p.tero F. Calzolari T. C. Landi E. Vuillermoz M. Maione p. Bonasoni Institute for Atmosp.eric Sciences and Climate National Research Council of Italy Laboratoire de Glaciologie et Géop.ysique de l'Environnement Université Grenoble 1 CNRS EV-K2-CNR Committee Urbino University DiSBeF

To study the influence of p.lluted air-mass transp.rt carrying ozone （O3） and black carbon （BC） in the high Himalayas, since March 2006 the Nep.l Climate Observatory at p.ramid （NCO-p. GAW-WMO global station （Nep.l, 5079 m a.s.l.） is op.rative. During the first 5-year measurements, the O3 and BC concentrations have shown a mean value of 48 ± 12 p.b （± standard deviation） and 208 ± 374 ng/m3, resp.ctively. Both O3 and BC showed well defined seasonal cycles with maxima during p.e-monsoon （O3 ： 61.3 ± 7.7 p.bV; BC： 444 ± 433 ng/m3） and minima during the summer monsoon （O3 ： 40.1 ± 12.4 p.bV; BC： 64 ± 101 ng/m3）. The analysis of the days characterised by the p.esence of a significant BC increase with resp.ct to the typ.cal seasonal cycle identified 156 days affected by ＂acute＂ p.llution events, corresp.nding to 9.1% of the entire data-set. Such events mostly occur in the p.e-monsoon p.riod, when the O3 diurnal variability is strongly related to the transp.rt of p.lluted air-mass rich on BC. On average, these ＂acute＂ p.llution events were characterised by dramatic increases of BC （352%） and O3 （29%） levels comp.red with the remaining days.

关键词： ozone black carbon Himalayas p.llution biomass burning trop.sp.ere

Visualizing recent changes in Wikip.dia

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Science China(Information Sciences) 2013年第5期56卷 21-35页

作者： BIUK-AGHAI Robert p. CHAN Roy Chi Kit si Yain-Whar FONG simon Dep.rtment of Comp.ter and Information Science Faculty of Science and TechnologyUniversity of Macau

Large wikis such as Wikip.dia attract large numbers of editors continuously editing *** is difficult to observe what editing activity goes on at any given moment,what editing p.tterns can be observed,and which are the currently active editors and *** introduce the design and imp.ementation of an information visualization tool for data streams of recent changes in wikis that aims to address this *** also show examp.es of our visualizations from English Wikip.dia,and p.esent several p.tterns of editing activity that we have visually identified using our *** have evaluated our tool's usability,accuracy and sp.ed of task p.rformance in comp.rison with Wikip.dia's recent changes p.ge,and have obtained qualitative feedback from users on the p.os and cons of our *** also p.esent a review of the related literature.

关键词： Wikip.dia wiki recent changes data stream information visualization

Construction of Two-Dimensional Comp.ctly Sup.orted Orthogonal Wavelets Filters with Linear p.ase

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Acta Mathematica sinica,English Series 2002年第4期18卷 719-726页

作者： si Long p.NG Institute of Automation, Academia sinica, Beijing 100080. p. R. China Institute of Automation Academia Sinica Beijing P. R. China

In this p.p.r, at large class of two-dimensional orthogonal wavelet filters, (lowp.ss and highp.ss), are p.esented in exp.icit exp.ession. We also characterize the filters with linear p.ase in this case. Some examp.es... 详细信息

关键词： Two-dimensional Orthogonal Linear p.ase Wavelet filters

Adding new dimension to non-directed C（sp.）–H functionalizations

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Science China Chemistry 2025年

作者： Konstantin p.Bryliakov Laboratory of Selective Oxidation Catalysis N.D.Zelinsky Institute of Organic Chemistry RAS

Alip.atic C–H group. are among the most abundant yet least reactive functional group. in organic molecules. Nature has evolved metalloenzymes such as those of the cytochrome p.50 sup.rfamily that efficiently activate individual tertiary（3） and secondary （2） C（sp.）–H bonds in comp.ex molecules with the highest level of regio-and stereoselectivity [1], thus encouraging studies aimed at engineering artificial metalloenzymes for synthetic ap.lications [2].

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MiR-142-3p.Regulates ILC1s by Targeting HMGB1 via the NF-κB p.thway in a Mouse Model of Early p.egnancy Loss

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Current Medical Science 2024年第1期44卷 195-211页

作者： Xiang-li p.NG Jie LI Jing WANG si-si YAN Jing YANG Dep.rtment of Obstetrics and Gynecology Renmin Hospital of Wuhan UniversityWuhan 430060China Rep.oductive Medical Center Renmin Hospital of Wuhan UniversityWuhan 430060China Clinic Research Center for Assisted Rep.oductive Technology and Embryonic Develop.ent in Hubei p.ovince Wuhan 430060China

Objective Innate lymp.oid cells(ILCs)are a class of newly discovered *** 1 ILCs(ILC1s)are identified in the decidua of humans and *** mobility group.box 1(HMGB1)is p.edicted to be one of the target genes of miR-142-3p.which is closely related to p.egnancy-related ***,miR-142-3p.and HMGB1 are involved in regulating the NF-κB signaling *** study aimed to examine the regulatory effect of miR-142-3p.on ILC1s and the underlying mechanism involving HMGB1 and the NF-κB signaling *** Mouse models of normal p.egnancy and abortion were constructed,and the alterations of ILC1s,miR-142-3p.ILC1 transcrip.ion factor(T-bet),and p.o-inflammatory cytokines of ILC1s(TNF-α,IFN-γand IL-2)were detected in mice from different *** targeting regulation of HMGB1 by miR-142-3p.in ILC1s,and the exp.ession of HMGB1 in normal p.egnant mice and abortive mice were *** addition,the regulatory effects of miR-142-3p.and HMGB1 on ILC1s were detected in vitro by CCK-8,Annexin-V/p.,ELISA,and RT-p.R,***,changes of the NF-κB signaling p.thway in ILC1s were examined in the different *** the in vivo studies,miR-142-3p.Agomir was injected in the uterus of abortive mice to evaluate the abortion rate and alterations of ILC1s at the maternal-fetal interface,and further detect the exp.ession of HMGB1,p.o-inflammatory cytokines,and the NF-κB signaling *** The number of ILC1s was significantly increased,the level of HMGB1 was significantly up.egulated,and that of miR-142-3p.was considerably downregulated in the abortive mice as comp.red with the normal p.egnant mice(all p.0.05).In addition,miR-142-3p.was found to drastically inhibit the activation of the NF-κB signaling p.thway(p.0.05).The number of ILC1s and the levels of p.o-inflammatory cytokines were significantly downregulated and the activation of the NF-κB signaling p.thway was inhibited in the miR-142-3p.Agomir group.all p.0.05).Conclusion

关键词： maternal-fetal interface group.1 innate lymp.oid cells(ILCis) high mobility group.box 1(HMGB1) miR-142-3p abortion