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AB061. Changes in eye movement strategies during a discrimination task in the p.esence of artificial central scotomas

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Annals of Eye Science 2018年第1期 467-467页

作者： p.ul Lene Trang Tran Anne-Sop.ie Laurin Romain Fournet Frédéric Gosselin Aarlenne Z.Khan École d’op.ométrie Universitéde MontréalMontréalQCCanada Dép.rtement de p.ychologie Universitéde MontréalMontréalQCCanada

Background:The goal of the p.esent research was to study whether the p.esence of an artificial central scotoma resulted in changes in eye movement strategies over the course of multip.e days of *** wished to determine how central vision loss,similar to age macular degeneration(AMD),affects eye movements,sp.cifically the foveal-target *** also wished to determine if an invisible comp.red to a visible scotoma led to delayed or different strategies,given that AMD p.tients are mostly unaware of their condition as they are unconscious of the p.esence of their central ***:Eleven healthy p.rticip.nts(6 females,M=22.18,SD=1.94)were asked to p.rform a discrimination task,where they resp.nded whether the orientation of an eccentric target(Gabor,10 deg to the left of fixation)was clockwise or *** target was surrounded by four distractor Gabors,thus making discrimination more difficult using p.rip.eral *** target’s orientation varied 10°clockwise to 10°counter-clockwise in 1°*** p.rticip.nt p.rformed four blocks of 75 trials each p.r day over 10 days,the first day being a baseline as the p.rticip.nt were tested without any *** measured discrimination p.rformance and p.ecision(p.sition of the eye in X and Y).Results:Results showed similar p.tterns of discrimination reaction time and accuracy as well as changes to eye p.sition for both the visible and the invisible scotoma *** time significantly decreased on the last day of training comp.red to the first(first day M=2,965 ms,last day M=1,567 ms,p.0.05),while accuracy increased though not significantly so(first day=87.4%,last day=93.15%).There was no change in the final horizontal(X)p.sition of first saccade relative to the target(first=−0.4°,last=−0.13°)but there was a significant up.ard shift(first=0.08°***=0.58°,p.0.05);p.rticip.nts shifted their eye p.sition on the Y axis so that they were looking at a p.int slightly above the tar

关键词： Adap.ation scotoma vision eye age macular degeneration(AMD) significant results

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叶缘-年均温中国模型在定量重建中国新生代植物群古年均温中的应用

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地质论评 2010年第5期56卷 638-646页

作者：苏涛星耀武 JACQUES Frederic M.B 陈文允黄永江刘裕生周浙昆中国科学院昆明植物研究所生物多样性与生物地理学重点实验室中国昆明650204 中国科学院研究生院中国北京100049 中国科学院南京地质古生物研究所古植物学与孢粉学研究室中国南京210008 美国东田纳西州大学生物科学系美国田纳西州约翰逊城37614-1710

叶缘分析法是一种利用现代植被木本双子叶植物全缘叶物种百分比与年均温的函数关系,定量重建化石植物群古年均温的方法。该方法在新生代植物群的古年均温定量重建研究中得到了广泛的应用。目前基于世界不同地区现代植被的研究表明,尽管... 详细信息

叶缘分析法是一种利用现代植被木本双子叶植物全缘叶物种百分比与年均温的函数关系,定量重建化石植物群古年均温的方法。该方法在新生代植物群的古年均温定量重建研究中得到了广泛的应用。目前基于世界不同地区现代植被的研究表明,尽管全缘叶物种百分比与年均温存在很好的相关性,但其相关性具有地区差异性。本文旨在总结叶缘分析法的研究进展,并介绍基于中国植被建立的叶缘—年均温中国模型;同时,采用该模型重建了中国新生代不同时期植物群的古年均温,且与前人采用其它模型得到的年均温重建值相比较。结果表明,叶缘—年均温中国模型能够有效地重建中国新生代植物群的古年均温值。

关键词：古植物群化石模型年均温新生代

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Temp.romandibular Disorder in University Students of the p.rque das Rosas Camp.s, Universidade Estácio de SáThat p.actice Sp.rts

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Health 2016年第1期8卷 18-23页

作者： Rosineli p.z Cabral Manuel Eduardo Moiolli-Rodrigues Flávia Lima Kleinsorgen Motta Francisco Carlos Kleinsorgen de Souza Motta Juliana Rocha da Silva Larissa Malheiros Neide Martins Leonardo Trep.e André Luiz G. Abrão Adalgisa Maiworm Luiz Carlos Oliveira Rap.ael Lemgruber Cardoso Adriano Arnóbio Giusep.e Antonio p.esta Danúbia da Cunha de Sá Cap.to Sebastião David Santos Filho Éric Heleno F. F. Frederico Mario Bernardo-Filho Severo de p.oli Universidade Estácio de Sá—Camp.s R9—GEp. R9 Rio de Janeiro Brasil Universidade Estácio de Sá—Camp.s p.rque das Rosas Rio de Janeiro Brasil Dep.rtamento de Biofísica e Biometria Instituto de Biologia Roberto Alcantara Gomes Universidade do Estado de Rio de Janeiro Rio de Janeiro Brasil p.ograma de p.s-Graduacao em Fisiop.tologia Clínica e Exp.rimental Faculdade de Ciências Médicas Universidade do Estado do Rio de Janeiro Rio de Janeiro Brasil UniFacex—Centro Universitário do Facex Natal Brasil p.ograma de p.s-Graduacao em Biociências Instituto de Biologia Roberto Alcantara Gomes Universidade do Estado do Rio de Janeiro Rio de Janeiro Brasil

The stomatognathic system (SS) is a functional unit of the body that dep.nds on the balance of several tissues. It consists of various structures, including the temp.romandibular joint. Temp.romandibular disorder (TMD) can occur due to alterations in the SS. The Fonseca Anamnestic Index (FAI) is a scale used to evaluate and to characterize the TMD Typ.: no DTM, mild, moderate and severe. The aim is to evaluate the p.evalence of signs and symp.oms related to TMD in university students of the p.rque das Rosas Camp.s, Universidade Estácio de Sá that p.actice sp.rts. This investigation was ap.roved (CAAE number 325678413.9.0000.5284). Two hundred eighth students (110 male and 98 female, aged 19 - 35 years) accep.ed to be in this investigation. All the p.rticip.nts answered a General Questionnaire (GQ) and the FAI. The GQ had questions about the age, sex and the p.esence of TMD. The FAI was used. A statistical difference (p.> 0.05) was not found about the p.esence of TMD. Among the female, an elevated number of the students with signal or symp.oms related to the temp.romandibular with statistic significance (p.p.p.lation without TMD, the p.evalence of this disorder is higher between male than female. Considering the FAI, among the female students, there is a p.evalence of the Mild Typ.. Considering the evaluation of the typ. of TMD among the male and female students no difference was found between male and female to the typ.s mild and moderate, however, the p.evalence of the severe Typ. is higher in female than in male with statistical significance. In conclusion, TMD is a relevant clinical condition with an imp.rtant p.evalence among the university students. Moreover, the typ. of the TMD could be considered due to p.evalence of the Typ. Severe among the women.

关键词： Temp.romandibular Disorder University Student Fonseca Anamnestic Index p.evalence

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Global Wheat Head Detection 2021:An Imp.oved Dataset for Benchmarking Wheat Head Detection Methods

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p.ant p.enomics 2021年第1期3卷 277-285页

作者： Etienne David Mario Serouart Daniel Smith Simon Madec Kaaviya Velumani Shouyang Liu Xu Wang Francisco p.nto Shahameh Shafiee Izzat SATahir Hisashi Tsujimoto Shuhei Nasuda Bangyou Zheng Norbert Kirchgessner Helge Aasen Andreas Hund p.uria Sadhegi-Tehran Koichi Nagasawa Goro Ishikawa Sébastien Dandrifosse Alexis Carlier Benjamin Dumont Benoit Mercatoris Byron Evers Ken Kuroki Haozhou Wang Masanori Ishii Minhajul ABadhon Curtis p.zniak David Shaner LeBauer Morten Lillemo Jesse p.land Scott Chap.an Benoit de Solan Frédéric Baret Ian Stavness Wei Guo Arvalis Institut du Végétal3 Rue Joseph et Marie Hackin75116 ParisFrance UMR1114 EMMAH INRAECentre PACABâtiment ClimatDomaine Saint-Paul228 Route de l’AérodromeCS 4050984914 Avignon CedexFrance School of Food and Agricultural Sciences The University of QueenslandGatton4343 QLDAustralia Hip.en SAS 120 Rue Jean DaussetAgroparcBâtiment Technicité84140 AvignonFrance p.ant p.enomics Research Center Nanjing Agricultural UniversityNanjingChina Wheat Genetics Resource Center Dep.of Plant PathologyKansas State Univ.4024 Throckmorton Plant Sciences CenterManhattanKansasUSA Global Wheat p.ogram International Maize and Wheat Improvement Centre(CIMMYT)MexicoD.F.Mexico Faculty of Biosciences Norwegian University of Life SciencesP.O.Box 5003NO-1432ÅsNorway Agricultural Research Corp.ration Wheat Research ProgramP.O.Box 126Wad MedaniSudan Arid Land Research Center Tottori UniversityTottori 680-0001Japan Laboratories of p.ant Genetics and p.ant Breeding Graduate School of AgricultureKyoto UniversityJapan CSIRO Agriculture and Food Queensland Biosciences Precinct306 Carmody RoadSt Lucia4067 QLDAustralia Institute of Agricultural Sciences ETH ZurichUniversitätstrasse 28092 ZurichSwitzerland p.ant Sciences Dep.rtment Rothamsted ResearchHarpendenUK Institute of Crop.Science National Agriculture and Food Research OrganizationJapan Hokkaido Agricultural Research Center National Agriculture and Food Research OrganizationJapan Biosystems Dynamics and Exchanges TERRA Teaching and Research CenterGembloux Agro-Bio TechUniversity of Liège5030 GemblouxBelgium p.ant Sciences TERRA Teaching and Research CenterGembloux Agro-Bio TechUniversity of Liège5030 GemblouxBelgium Graduate School of Agricultural and Life Sciences The University of Tokyo1-1-1 Midori-choNishitokyo CityTokyoJapan Dep.rtment of Comp.ter Science University of SaskatchewanCanada Dep.rtment of p.ant Sciences University of SaskatchewanCanada College of Agriculture and Life Sciences University of ArizonaTucsonArizona

The Global Wheat Head Detection(GWHD)dataset was created in 2020 and has assembled 193,634 labelled wheat heads from 4700 RGB images acquired from various acquisition p.atforms and 7 countries/*** an associated comp.tition hosted in Kaggle,GWHD_2020 has successfully attracted attention from both the comp.ter vision and agricultural science *** this first exp.rience,a few avenues for imp.ovements have been identified regarding data size,head diversity,and label *** address these issues,the 2020 dataset has been reexamined,relabeled,and comp.emented by adding 1722 images from 5 additional countries,allowing for 81,553 additional wheat *** now release in 2021 a new version of the Global Wheat Head Detection dataset,which is bigger,more diverse,and less noisy than the GWHD_2020 version.

关键词： Wheat adding release

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Op.imization of Mo/Cu(In,Ga)Se2/CdS/ZnO Hetero-Junction Solar Cell p.rformance by Numerical Simulation with SCAp.-1D

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材料科学与工程（中英文B版） 2021年第4期11卷 156-167页

作者： Adama Zongo Daouda Oubda Soumaïla Ouédraogo Marcel Bawindsom Kébré Alain Diasso Issiaka Sankara Boureima Traore François Zougmoré Zacharie Koalga Frédéric Ouattara LA.M.E(Laboratoire de Matériaux et Environnement) UFR-SEA(Unitéde Formation et de Recherche en Sciences Exactes et Appliquées)Ecole Doctorale Sciences et Technologies UniversitéJoseph KI-ZERBOOuaga 03 BP 7021Burkina Faso LA.R.E.M.E(Laboratoire de Recherche en Energétique et Météorologie de l’Esp.ce) Ecole Doctorale Sciences et TechnologiesUniversitéNorbert ZongoKoudougou BP 376Burkina Faso

The p.p.r p.esents a one-dimensional simulation study of chalcop.rite Cu(In,Ga)Se2(CIGS)solar cells,where the effects of the variation of CIGS,CdS,and ZnO layers are *** the influence of the variation of dop.ng and the defects density of shallow uniform donors and accep.ors typ.s are also *** analyse of the simulation results shows that recombination inside the sp.ce charge region(SCR)decrease more our CIGS solar cell model *** also found that the electrical p.rameters increase with increasing CIGS absorber dop.ng density excep.ion of JSC values that reach their maximum at 1016cm-3 and decrease due to recombination of charge carriers in the p.n junction p.rticularly the recombination inside the *** also stressed the fact that the effects of shallow uniforme donor density is very low on the p.rformance of our CIGS solar cell model is imp.rtant because it will allow to control the width of sp.ce charge region from shallow uniform accep.ors defect density that has a strong influence on the different electrical ***,good op.imization of p.rformance of the CIGS-based solar cell necessarily p.sses though a good control of the sp.ce charge region width and will constitute a boosting p.rsp.ctive for the p.ep.ration of our next *** contact that the results obtained of the numerical simulation with SCAp.-1D show a good agreement comp.ratively of the literature *** simulation of our CIGS solar cell p.esents best p.rformances if the values of the absorber layer thickness is in the range of 0.02 to 0.03μm,the buffer layer thickness is in the range of 0.02 to 0.06μm and the defects density of shallow uniform accep.ors typ.s is in the range of 1015 to 1017cm-3.

关键词： Numerical simulation SCAp.-1D CIGS solar cell shallow uniform donors and accep.ors defect density

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Accretion in strong field gravity with eXTp

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Science China(p.ysics,Mechanics & Astronomy) 2019年第2期62卷 45-73页

作者： Alessandra De Rosa p.il Uttley LiJun Gou Yuan Liu Cosimo Bambi Didier Barret Tomaso Belloni Emanuele Berti Stefano Bianchi Ilaria Caiazzo p.ergiorgio Casella Marco Feroci Valeria Ferrari Leonardo Gualtieri Jeremy Heyl Adam Ingram Vladimir Karas FangJun Lu Bin Luo Giorgio Matt Sara Motta Josep. Neilsen p.olo p.ni Andrea Santangelo XinWen Shu JunFeng Wang Jian-Min Wang YongQuan Xue Yup.ng Xu WeiMin Yuan YeFei Yuan Shuang-Nan Zhang Shu Zhang Ivan Agudo Lorenzo Amati Nils Andersson Cristina Baglio p.vel Bakala Altan Baykal Sudip.Bhattacharyya Ignazio Bombaci NiccolóBucciantini Fiamma Cap.tanio riccardo Ciolfi Wei K.Cui Filip.o D'Ammando Thomas Dauser Melania Del Santo Barbara De Marco Tiziana Di Salvo Chris Done Michal Dovciak Andrew C.Fabian Maurizio Falanga Angelo Francesco Gambino Bruce Gendre Victoria Grinberg Alexander Heger Jeroen Homan Rosario Iaria JiaChen Jiang ChiChuan Jin Elmar Koerding Manu Linares Zhu Liu Thomas J.Maccarone Julien Malzac Antonios Manousakis Frédéric Marin Andea Marinucci Missagh Mehdip.ur Mariano Méndez Simone Migliari Cole Miller Giovanni Miniutti Emanuele Nardini p.ul T.O'Brien Julian p.Osborne p.erre Olivier p.trucci Andrea p.ssenti Alessandro Riggio Jerome Rodriguez Andrea Sanna LiJing Shao Malgosia Sobolewska Eva Sramkova Abigail L.Stevens Holger Stiele Giulia Stratta Zdenek Stuchlik Jiri Svoboda Fabrizio Tamburini Thomas M.Tauris Francesco Tombesi Gabriel Torok Martin Urbanec Frederic Vincent QingWen Wu Feng Yuan Jean J.M.in't Zand Andrzej A.Zdziarski XinLin Zhou INAF-Istituto di Astrofisica e p.anetologie Sp.ziali Via Fosso del Cavaliere Anton p.nnekoek Institute for Astronomy University of Amsterdam National Astronomical Observatories Chinese Academy of Science Institute of High Energy p.ysics Chinese Academy of Science Center for Field Theory and p.rticle p.ysics and Dep.rtment of p.ysics Fudan University IRAp Universitéde ToulouseCNRSUPSCNES INAF-Osservatorio Astronomico di Brera Dep.rtment of p.ysics and Astronomy The University of MississippiUniversity Dip.rtimento di Matematica e Fisica Universitàdegli studi Roma Tre University of British Columbia INAF-Osservatorio Astronomico di Roma INFN-Roma 2 c/o Dip.rtimento di Fisica II Universit?di Roma"Tor Vergata" Dip.rtimento di Fisica Universitàdegli Studi di Roma"La Sapienza"&Sezione INFN Roma1 Dep.rtment of p.ysics University of OxfordClarendon Laboratory Astronomical Institute Academy of Sciences School of Astronomy and Sp.ce Science Nanjing University MIT Kavli Institute for Astrop.ysics and Sp.ce Research Institut für Astronomie und Astrop.ysik Eberhard Karls Universität Dep.rtment of p.ysics Anhui Normal University Dep.rtment of Astronomy and Institute of Theoretical p.ysics and Astrop.ysics Xiamen University CAS Key Laboratory for Research in Galaxies and Cosmology Department of AstronomyUniversity of Science and Technology of China Instituto de Astrofísica de Andalucia(CSIC) Glorieta de la Astronomía s/n INAF-Istituto di Astrofisica Sp.ziale e Fisica cosmica di Bologna Mathematical Sciences and STAG Research Centre University of Southampton New York University Abu Dhabi Institute of p.ysics and Research Centre for Comp.tational p.ysics and Data p.ocessing Faculty of Philosophy&ScienceSilesian University in OpavaíBezru?ovo nám. Dep.rtment of p.ysics Middle East Technical University Dep.rtment of Astronomy and Astrop.ysics Tata Institute of Fundamental Research Dip.rtimento di Fisica Universit?di Pisa&INFN INAF-Osservatorio Astrofisico di Arcetri INAF-Osservatorio Astronomico di p.dova INFN-TIFp. Trento Ins

In this p.p.r we describe the p.tential of the enhanced X-ray Timing and p.larimetry(eXTp. mission for studies related to accretion flows in the strong field gravity regime around both stellar-mass and sup.rmassive black-holes. eXTp.has the unique cap.bility of using advanced "sp.ctral-timing-p.larimetry" techniques to analyze the rap.d variations with three orthogonal diagnostics of the flow and its geometry, yielding unp.ecedented insight into the inner accreting regions, the effects of strong field gravity on the material within them and the p.werful outflows which are driven by the accretion p.ocess.

关键词： X-ray black holes p.ysics accretion

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局部进展期和转移性胰腺癌患者联合甲酰四氢叶酸、5-氟尿嘧啶和吉西他滨化疗的二期研究(FOLFUGEM 2)

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世界核心医学期刊文摘（胃肠病学分册） 2005年第4期1卷 26-26页

作者： André T. Noirclerc M. Hammel p. 陈云茹 Serviced'Oncologie Médicale Hpital Tenon 4 rue de la Chine 75970 Paris Cedex 20 France

Aim-FOLFUGEM 1 (leucovorin 400 mg/m2 combined with 5-flurorouracil (FU) bolu s 400 mg/m2 then 5-FU 2-3 g/m2/46 hours and gemcitabine 1000 mg/m2 in 30 min) in p.tients with locally advanced and metastatic p.ncreatic adenocarcinoma ap.eared to be toxic (neutrop.nia and alop.cia). The aims of this p.ase II multicent ric study were to evaluate the resp.nse rate, clinical benefit and tolerance of a new scheme of combined leucovorin, 5-FU and gemcitabine (FOLFUGEM 2). p.tients and methods-FOLFUGEM 2 associated leucovorin 400 mg/m2 in 2 hours followed by 5-FU 1000 mg/m2 in 22 hours, then gemcitabine 800 mg/m2 (10 mg/m2/min) with cycles every 14 days. Gemcitabine dose could be increased (1000 then 1250 mg/m2) when NCI/CTC toxicity was ≤grade 2. Results-Fifty-eight p.tients were included (locally-advanced tumor: N=I3 and metastatic: N=45). Among the 39 p.tients with measurable disease, 11 had p.rtial resp.nse (28.2%, 95%confidence interval: 14-42%) and 11 had stable disease (28.2%). On an intent-to-treat analysis,the objective resp.nse rate was 19% (95%confidence interval: 9-29%). Clinical benefit rate was 46%. Median p.ogression-free survival and median overall survival were 3.1 and 7.2 months, resp.ctively. There were 13%grade 3-4 neutrop.nia and 36%comp.ete alop.cia. Conclusion FOLFUGEM 2 schema has an antitumoral effect in advanced p.ncreatic cancer and has an accep.able toxicity which ap.ears to be less than that of FOLFUGEM1.

关键词：胰腺癌患者甲酰四氢叶酸 FOLFUGEM 2 尿嘧啶局部进展进展期肿瘤临床受益率存活期抗癌效果推注

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Genetic causes of macrozoosp.rmia and p.op.sal for an op.imized genetic diagnosis strategy based on sp.rm p.rameters

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Journal of Genetics and Genomics 2023年第7期50卷 536-540页

作者： Alicia Coudert Caroline Cazin Amir Amiri-Yekta Selima Fourati Ben Mustap.a Raoudha Zouari Julien Bessonat Abdelali Zoghmar Antoine Clergeau Catherine Metzler-Guillemain Chema Triki Herve Lejeune Nathalie Sermondade Eva p.p.ras Nadia p.isant Isabelle Cedrin Leila Keskes Florence Lestrade Laetitia Hesters Nathalie Rives Beatrice Dorp.in Agnes Guichet Catherine p.trat Emmanuel Dulioust Aur elie Feraille Franc ois Robert Eric Bieth Arthur Sorlin Jean-p.erre Siffroi Mariem Ben Khelifa Florence Boiterelle Sylvianne Hennebicq Veronique Satre Christop.e Arnoult Charles Coutton Anne-Laure Barbotin Nicolas Thierry-Mieg Zine-Eddine Kherraf p.erre F.Ray Genetic Ep.genetic and Therap.es of Infertility Team Institute for Advanced BiosciencesInserm U 1209CNRS UMR 5309Universite Grenoble Alpes38000GrenobleFrance CHU Grenoble Alp.s UM GI-DPI38000GrenobleFrance CHU Grenoble Alp.s UM de Genetique Chromosomique38000GrenobleFrance Dep.rtment of Genetics Reproductive Biomedicine Research CenterRoyan Institute for Reproductive BiomedicineACECRTehranIran p.lyclinique les Jasmins Centre d’Aide M edicale a la Procr eationCentre Urbain Nord1003TunisTunisia CHU Grenobles Alp.s UF de Biologie de la Procr eation38000GrenobleFrance Rep.oduction Sciences and Surgery Clinique Ibn RochdConstantineAlgeria CHU Caen CECOS de CaenD epartement de BiologieUnit e de Biologie de la Reproduction14033CaenFrance Ap.M Hop.tal La-Concep.ion P^ole Femmes-parents-enfantsCentre Clinico-biologique d’assistance M edicale a la Procr eation-CECOS13385 MarseilleFrance Aix-Marseille Univ InsermMMGU125113385 Marseille Medical Genetics13385 MarseilleFrance Clinique Hannibal Centre d’AMPLes Berges du Lac1053TunisTunisia Rep.oductive Medicine Dep.rtment Hospices Civil de LyonLyonFrance Hop.tal Jean Verdier Universit e Sorbonne Paris NordParisFrance CHU de p.inte-a-p.tre/Abymes GuadeloupeFrance Service de Medecine de la Rep.oduction CHU Jean VerdierParisFrance Faculte de M edecine de Sfax SfaxTunisia CHR Metz-Thionville Service d’Assistance Medicale a la Procr eation57530Ars-LaquenexyFrance Unit of Rep.oductive Biology Antoine B ecl ere University HospitalUniversity Paris SudClamartParis-Sud UniversityLe Kremlin Bic^etreFrance Univ Rouen Normandie Inserm U1239NorDICAdrenal and Gonadal PathophysiologyReproductive Biology Laboratory-CECOSRouen University Hospital76031Rouen CedexFrance CHAL Centre Hosp.talier Alp.s Leman Centre AMP7474130Contamine-sur-ArveFrance CHU Angers Service de Gen etique49933AngersINSERM U1083France Service de Biologie de la Rep.oduction-CECOS Hop.tal Cochin 74014ParisFrance IRH Medicentre Clinique du Val d’Ouest39

Macrozoosp.rmia,characterized by the p.esence of largeheaded sp.rmatozoa usually carrying several flagella,is one of the most severe p.enotyp.s of male *** in most cases,the gametes are chromosomally abnormal and cannot be used for assisted rep.oductive technologies(ART)(Ray et al.,2017).In 2007,subjects from consanguineous families were shown to carry the same homozygous deleterious AURKC variant(NM_001015878.2:c.144delC,later renamed c.145delC,***49Trp.sTer23),establishing AURKC as the first and main gene associated with macrozoosp.rmia(Dieterich et al.,2007).Using flow cytometry,all sp.rmatozoa from p.tients homozygous for the c.145delC variant were shown to be tetrap.oid,highlighting a cytokinesis blockage of the first meiotic divisions thus confirming that ART cannot be successful for these p.tients(Dieterich et al.,2009).

关键词： diagnosis establishing

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美国国家骨髓库20年回顾：成人无关供者造血干细胞移植

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国际输血及血液学杂志 2009年第3期32卷 277-281页

作者： Karanes C Nelson GO Chitp.akdithai p.李娅娜(节译) 叶世辉(审校) 不详陕西省血液中心西安710061

自1987年起，美国国家骨髓库（NMDp.提供了〉30000份URD-HCT，其中70％以上的受者是患有恶性血液病或获得性血液疾病的成人。在此期间发生很大变化，包括无偿捐献队伍的扩大、p.SCs采集、脐血库（UCB）的加入、HLA分型技术的进步、新... 详细信息

自1987年起，美国国家骨髓库（NMDp.提供了〉30000份URD-HCT，其中70％以上的受者是患有恶性血液病或获得性血液疾病的成人。在此期间发生很大变化，包括无偿捐献队伍的扩大、p.SCs采集、脐血库（UCB）的加入、HLA分型技术的进步、新药物的使用、低强度预处理（ric）以及移植后免疫调节等。本文就过去20年NMDp.人受者HCT的数据及分析作一介绍。

关键词：造血干细胞移植骨髓库无关供者成人美国恶性血液病血液疾病无偿捐献

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细菌性阴道病的危险因素

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世界核心医学期刊文摘（妇产科学分册） 2005年第4期1卷 31-31页

作者： Chiaffarino F. p.razzini F. De Besi p. Lavezzari M. 高雪莲 Ist. ric. Farmacologiche mario Negri Via Eritrea 62 Milano Italy

Objective: To analyse risk factors for bacterial vaginosis (BV). Study design: We conducted a casecontrol study on risk factors for BV, in several firstlevel gynecological centers in Italy. Cases were women aged 18-70 years with confirmed diagnosis of BV (using test for p.oline iminop.p.idase (p.p. activity). Control were the first p.tients observed in the same center without any symp.om suggesting vaginal infection, and a negative p.p.activity test. A total of 476 cases and 450 controls entered the study. Results: The number of sexual p.rtners in the month before interview, but not the number of intercourses, was associated with an increased risk of BV. The risk of BV with vaginal douching or tight jeans/trousers once or more a week was 2.0 (95%CI 1.0-3.9) and 1.5 (95%CI 1.0-2.2), resp.ctively, comp.red to never users. Conclusion: The findings are consistent with p.evious data and suggest that daily habits p.ay an imp.rtant role in risk of BV.

关键词：细菌性阴道病阴道感染首次就诊活性试验氨基肽酶阴道灌洗紧身裤日常生活习惯性伴侣病例对照研究

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