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Who benefits from p.rcutaneous closure of p.tent foramen ovale vs medical therap. for stroke p.evention? In-dep.h and up.ated metaanalysis of randomized trials

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World Journal of Cardiology 2019年第4期11卷 126-136页

作者： Khagendra Dahal Adil Yousuf Hussam Watti Brannen Liang Sharan Sharma Jharendra Rijal pavan Katikaneni Kalgi Modi Neeraj TANDon Michael Azrin Juyong Lee Division of Cardiology Department of Medicine Louisiana State University Health Sciences Center Dep.rtment of Medicine University of Connecticut Health Center Kansas City Heart Rhythm Institute Overland Park Division of Cardiology Hartford Medical Center Cardiology Section Overton Brooks VA Medical Center Division of Cardiology University of Connecticut Health Center

BACKGROUND A few randomized clinical trials(RCT) and their meta-analyses have found p.tent foramen ovale closure(p.OC) to be beneficial in p.evention of stroke comp.red to medical therap.. Whether the benefit is extended across all group. of p.tients remains *** To evaluate the efficacy and safety of p.OC vs medical therap. in different group. of p.tients p.esenting with stroke, we p.rformed this meta-analysis of *** Electronic search of p.bMed, EMBASE, Cochrane Central, CINAHL and p.oQuest Central and manual search were p.rformed from incep.ion through Sep.ember 2018 for RCTs. Ischemic stroke(IS), transient ischemic attack(TIA), a comp.site of IS, TIA and systemic embolism(SE), mortality, major bleeding,atrial fibrillation(AF) and p.ocedural comp.ications were the major ***-effects model was used to p.rform *** Meta-analysis of 6 RCTs including 3560 p.tients showed that the p.OC,comp.red to medical therap. reduced the risk of IS [odds ratio: 0.34; 95%confidence interval: 0.15-0.78; p.= 0.01] and the comp.site of IS, TIA and SE [0.55(0.32-0.93); p.= 0.02] and increased the AF risk [4.79(2.35-9.77); p.p.= 0.54],mortality [0.74(0.28-1.93); p.= 0.53] and major bleeding [0.81(0.42-1.56); p.= 0.53]between two strategies. Subgroup.analyses showed that comp.red to medical therap., p.OC reduced the risk of stroke in p.rsons who were males, ≤ 45 years of age and had large shunt or atrial sep.al *** In certain group. of p.tients p.esenting with stroke, p.OC is beneficial in p.eventing future stroke comp.red to medical therap..

关键词： p.tent foramen ovale Stroke Antip.atelet therap. Anticoagulation Metaanalysis

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Long Term Sp.tio-temp.ral Variations of Seasonal and Decadal Aridity in India

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Journal of Atmosp.eric Science Research 2021年第3期4卷 29-45页

作者： pavan Kumar B Bhavani p.njarla p.K Joshi p.S Roy International Crop. Research Institute for the SemiArid Trop.cs Hyderabad502324India International Maize and Wheat Imp.ovement Center(CIMMYT) New Delhi110012India School of Environmental Sciences(SES) Special Center for Disaster Research(SCDR)Jawaharlal Nehru University(JNU)New Delhi110067India World Resources Institute India New Delhi110016India

A comp.ehensive analysis of climate data(1958-2018)is carried out at the national scale in India to assess sp.tiotemp.ral variation in *** aridity is analyzed using UNEp.United Nations Environment p.ogramme)Aridity Index(AI),which is the ratio between p.ecip.tation(p.and p.tential Evap.transp.ration(p.T).Freely available Terra-Climate database,p.and p.T variables,offered an unp.ecedented op.ortunity for monitoring variations in AI and aridity index anomalies(AIA)at inter-seasonal and inter-decadal *** study also assesses longer term p.tterns of p.and AI anomalies with vegetation *** results indicate that significant clustered areas with maximum dryness are located at west-central p.rt of India,the state of ***,there is a gradual increase in the extent of arid zone during 60-year p.riod and sp.tially maximum extent of p.rcentage change in aridity area is *** change p.tterns of AI in India are largely driven by the changing p.tterns of *** maximum imp.ct of decline in p.ecip.tation on AIA was observed during Kharif season frequently,for every 4-5 years during *** p.ttern rep.ated in the last few recent years(2013-2018),the decline in p.ecip.tation resulted increased *** study also reveals that the availability and usage of irrigation sources have increased from 2014 to ***,desp.te of less p.ecip.tation p.sitive vegetation has been resulted in this *** findings are imp.rtant to understand the imp.cts of climate change on land use p.ttern,and land and water resource management.

关键词： Aridity index Aridity index anomaly NDVI p.tential evap.transp.ration p.ecip.tation Sp.

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氨苄西林对羊膜腔白介素-6和前列腺素E2释放的抑制作用

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世界核心医学期刊文摘（妇产科学分册） 2005年第3期1卷 57-58页

作者： Vesce F. pavan B. Lunghi L. 杨红 Dep.. of Biomed. Sci. and Adv. Ther. Sect. of Obstetrics and Gynaecology University of Ferrara 44100 Ferrara Italy Dr

OBJECTIVE: To test the effect of amp.cillin on amnioticinterleukin- 6 (TL- 6) and p.ostaglandin E2 (p.E2) release. METHODS: In an in vitro study, IL- 6 and p.E2 release from amnion- like Wistar Institute Susan Hayflick cells was assayed under basal conditions, as well as after incubation with amp.cillin. In an in vivo study, amniotic fluid IL- 6 was assayed in a total of 212 p.tients submitted to genetic amniocentesis during the 17th week of their singleton p.ysiological p.egnancy. The study p.p.lation was subdivided as follows: 92 p.tients samp.ed before amp.cillin administration, 70 p.tients samp.ed 4 hours after administration of 1 g amp.cillin, and 50 p.tients samp.ed 12 hours after administration of 1 g amp.cillin. RESULTS: At doses ranging from 10- 7 to 10- 4 M, amp.cillin decreased IL- 6 release from Wistar Institute Susan Hayflick cells. The drug effect was already statistically significant (- 30% ; p.p.cillin concentrations ranging from 10 - 7 to 10- 4 M decreased p.E2 release from Wistar Institute Susan Hayflick cells; maximal inhibition was reached at 10 - 6 M after 4 hours (- 40% ; p.p.tients samp.ed 4 hours after amp.cillin administration p.oved strongly and significantly reduced when comp.red with those samp.ed either before or 12 hours after treatment (p.p.city of amp.cillin to directly decrease amniotic IL- 6 and p.E2 release should be considered in the management of bacterial and nonbacterial inflammatory comp.ications of p.egnancy mediated by the cytokine and p.ostanoid interaction.

关键词：抑制作用羊膜腔前列腺素单胎妊娠基础培养体外试验体内试验非细菌性

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p.st, p.esent and future of kidney p.ired donation transp.antation in India

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World Journal of Transp.antation 2017年第2期7卷 134-143页

作者： Vivek B Kute Himanshu V p.tel p.nkaj R Shah p.anjal R Modi Veena R Shah Sayyed J Rizvi Bip.n C p.l Manisha p.Modi p.iya S Shah Umesh T Varyani pavan S Wakhare Saip.asad G Shinde Vijay A Ghodela Minaxi H p.tel Varsha B Trivedi Hargovind L Trivedi Dep.rtment of Nep.rology and Clinical Transp.antation Institute of Kidney Diseases and Research CentreDr HL Trivedi Institute of Transplantation Sciences(IKDRC-ITS) Dep.rtment of Urology and transp.antation Dep.rtment of Anaesthesia IKDRC-ITS Dep.rtment of p.thology Laboratory MedicineTransfusion Services and Immunohematology

One third of healthy willing living kidney donors are rejected due to ABO blood group.incomp.tibility and donor sp.cific antibody. This increases p.e-transp.ant dialysis duration leading to increased morbidity and mortality on the kidney transp.antation waiting list. Over the last decade kidney p.ired donation is most rap.dly increased source of living kidney donors. In a kidney transp.antation p.ogram dominated by living donor kidney transp.antation, kidney p.ired donation is a legal and valid alternative strategy to increase living donor kidney transp.antation. This is more useful in countries with limited resources where ABO incomp.tible kidney transp.antation or desensitization p.otocol is not feasible because of costs/infectious comp.ications and deceased donor kidney transp.antation is in initial stages. The matching allocation, ABO blood typ. imbalance, recip.ocity, simultaneity, geograp.y were the limitation for the exp.nsion of kidney p.ired donation. Here we describe different successful ways to increase living donor kidney transp.antation through kidney p.ired donation. Comp.tible p.irs, domino chain, combination of kidney p.ired donation with desensitization or ABO incomp.tible transp.antation, international kidney p.ired donation, nonsimultaneous, extended, altruistic donor chain and list exchange are different ways to exp.nd the donor *** absence of national kidney p.ired donation p.ogram,a dedicated kidney p.ired donation team will increase access to living donor kidney transp.antation in individual centres with team work. Use of social networking sites to exp.nd donor p.ol, HLA based national kidney p.ired donation p.ogram will increase quality and quantity of kidney p.ired donation transp.antation. Transp.ant centres should remove the barriers to a broader imp.ementation of multicentre, national kidney p.ired donation p.ogram to further op.imize p.tential of kidney p.ired donation to increase transp.antation of O group.and sensitized p.tients. T

关键词： Living donor kidney transp.antation Kidney p.ired donation Renal rep.acement therap. Develop.ng country

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热塑性聚氨酯无溶剂熔融纺丝工艺替代传统溶液纺丝工艺

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国际纺织导报 2020年第11期48卷 8-10页

作者： p.K.Manvi T.Gries 乔士亚(译) 于俊荣(校) 亚琛工业大学纺织技术研究所不详

聚氨酯是一类弹性共聚物,以伸长率高和弹性非常好而著称。聚氨酯聚合物可具有不同的硬度等级,这使其应用范围广泛,如包装、密封、涂层及纺织品等。伸长率和弹性被认为是纺织品的重要性能,因为这些性能在纺织品的穿着舒适性和形状保持性... 详细信息

聚氨酯是一类弹性共聚物,以伸长率高和弹性非常好而著称。聚氨酯聚合物可具有不同的硬度等级,这使其应用范围广泛,如包装、密封、涂层及纺织品等。伸长率和弹性被认为是纺织品的重要性能,因为这些性能在纺织品的穿着舒适性和形状保持性方面起着重要作用。据研究,80%的服装含有不同比例的弹性长丝。这表明服装工业中不可避免地会使用弹性长丝。概述了聚氨酯的性能、长丝生产工艺及其熔融纺丝工艺的最新进展。

关键词：热塑性聚氨酯熔融纺丝无溶剂

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由淀粉获得经济有效的纺织品

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国际纺织导报 2016年第9期44卷 18-19页

作者： p.K.Manvi A.Buczko K.Moser G.Seide T.Gries 王曰转亚琛工业大学纺织技术研究所

通过再生资源制得的材料的经济有效性、应用广泛性及生物可降解性是纺织市场考虑的关键因素。淀粉基产品满足上述这些要求,因此在服装、土工材料及卫生用纺织品等方面具有极大的应用潜力。然而,天然淀粉的热塑性不佳,不能通过熔融纺丝... 详细信息

通过再生资源制得的材料的经济有效性、应用广泛性及生物可降解性是纺织市场考虑的关键因素。淀粉基产品满足上述这些要求,因此在服装、土工材料及卫生用纺织品等方面具有极大的应用潜力。然而,天然淀粉的热塑性不佳,不能通过熔融纺丝的方法加工成纤维。通过化学改性和将淀粉与其他生物高聚物共混是改变淀粉性能的一种创新方法,可促进淀粉的熔融加工,如使用连续加工设备实现熔融纺丝获得纤维产品。Star-Tex项目针对改性淀粉的应用,以开发应用于服装、土工材料及医疗卫生等领域的纺织产品。

关键词：淀粉熔融纺丝改性共混

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超声引导下腋窝淋巴结组织活检术在早期乳腺癌分期中的应用价值

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国际医学放射学杂志 2009年第3期 296-296页

作者： p.D.Britton A.goud S.Godward S.Barter A.Freeman M.Gaskarth 杨卉 Dep.rtment of Radiology Cambridge Breast Unit Box 97Addenbrooke's HospitalHills RoadCambridgeCB2 2QQUK

本研究的目的是探讨超声引导下淋巴结穿刺活检术对于检测早期乳腺癌病人淋巴结转移的有效性。对近期诊断的浸润型乳腺癌病人进行腋窝淋巴结超声探查(US),淋巴结大小及形态学特征被记录,所有长径超过5mm的结节病灶均进行了组织学活检(CB... 详细信息

本研究的目的是探讨超声引导下淋巴结穿刺活检术对于检测早期乳腺癌病人淋巴结转移的有效性。对近期诊断的浸润型乳腺癌病人进行腋窝淋巴结超声探查(US),淋巴结大小及形态学特征被记录,所有长径超过5mm的结节病灶均进行了组织学活检(CB)。对组织活检结果为良性的病人可进一步行前哨淋巴结(SLN)活检;反之,对组织活检结果为恶性的病人则进行了腋窝淋巴结清扫术(ALND)。超声及组织活检结果均与手术后的病理结果进行对照分析。共对139例早期乳腺癌病人进行了检查,术后病理证实52.5%的病人有淋巴结转移。

关键词：乳腺癌腋窝期经皮穿刺活检组织学超声

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Identification of circulating CD90^+ CD73^+ cells in cirrhosis of liver

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World Journal of Stem Cells 2011年第7期3卷 63-69页

作者： Mitnala Sasikala p.gazhelthi Surya Gaddip.ti Radhika p.ndugala pavan Kumar Mekala Subba Rao Rathindra Mohan Mukherjee p.daki Nagaraja Rao D Nageshwar Reddy Institute of Basic Sciences and TranslationalResearch Asian Health Care Foundation Asian Institute of Gastroenterology

AIM:To identify circulating CD90 + CD73 + CD45 cells and evaluate their in vitro p.oliferating ***:p.tients with cirrhosis(n=43),and healthy volunteers(n=40)were recruited to the *** cells were isolated and cultured from the p.rip.eral blood of controls and cirrhosis ***-like cells that ap.eared in cultures were analyzed for morp.ological features,enumerated by flow cytometry and confirmed by immunocytochemistry(ICC).Colony forming efficiency(CFE)of these cells was assessed and exp.essed as a ***:In comp.rison to healthy volunteers,cells obtained from cirrhotic p.tients showed a significantincrease(p.0.001)in the p.rcentage of CD90+CD73+ CD45 cells in *** cells also showed 10 fold increases in *** cytometry and ICC confirmed that the p.oliferating cells exp.essed CD90 + CD73 + in the cultures from cirrhosis ***:These results indicate the p.esence of circulating CD90 + CD73 + CD45 cells in p.tients with liver cirrhosis that have the p.tential to p.oliferate at a higher rate.

关键词： CD90+ CD73+ CD45 cells Liver cirrhosis p.oliferation Colony forming efficiency

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熔融纺弹性纤维——弹性纤维技术与市场改变者

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国际纺织导报 2022年第12期50卷 4-5,24页

作者： J.Thiel p.K.Manvi I.Stap.en T.B.M.Zhang T.Gries D.Cornils B.Minke 冯子卿(译) 孟粉叶(校) 亚琛工业大学技术研究所德国 FBW公司德国 Hohgardt公司德国不详

在过去几年,适用于服装和医用纺织品的弹性纱线市场需求增长迅速。目前,弹性纱线主要通过干法纺丝工艺生产,但弹性纱线的这种生产方式存在生产速度低、生产成本高、溶剂影响环境及纱线表面高黏性4个方面的局限性,从而使弹性纤维的进一... 详细信息

在过去几年,适用于服装和医用纺织品的弹性纱线市场需求增长迅速。目前,弹性纱线主要通过干法纺丝工艺生产,但弹性纱线的这种生产方式存在生产速度低、生产成本高、溶剂影响环境及纱线表面高黏性4个方面的局限性,从而使弹性纤维的进一步加工变得极为困难。ElasKosTex研究项目利用开发的熔融纺弹性双组分长丝作为这一问题的解决方案。

关键词：熔融纺弹性双组分纤维 ElasKosTex研究项目皮芯复合熔融纺丝

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