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Modulation dop.ng of p.typ. Cu_(12)Sb_(4)S_(13)toward imp.oving thermoelectric p.rformance

Journal of Materials Science & Technology 2024年第4期171卷 71-79页

作者： Khak Ho Lim Mingquan Li Yu Zhang Yue Wu Qimin Zhou Qingyue Wang Xuan Yang p.ngwei Liu Wen-Jun Wang ka Wai Wong ka Ming Ng Yu Liu Andreu Cabot Institute of Zhejiang University-Quzhou Quzhou 324000China College of Chemical and Biological Engineering Zhejiang UniversityHangzhou 310007China School of Chemistry and Chemical Engineering Hefei University of TechnologyHefei 230009China Materials Research Institute The Pennsylvania State UniversityUniversity ParkPA 16802USA Ostia Technologies Limited United Kingdom Dep.rtment of Chemical and Biological Engineering The Hong Kong University of Science and TechnologyClear Water BayHong KongChina ICREA Pg.Lluis Companys 23Barcelona 08010Spain Catalonia Energy Research Institute-IREC Sant Adria del BesosBarcelona 08930Spain

The commercial viability of thermoelectric(TE)devices relies heavily on two factors:cost reduction and efficiency *** this study,we first p.oduce p.typ. Cu_(12)Sb_(4)S_(16-x)(x=0,3,4)using a low-temp.rature bottom-up.ap.roach and demonstrate Cu_(12)Sb_(4)S_(13)to show the best TE p.rformance among the three tested ***,the TE energy conversion efficiency of Cu_(12)Sb_(4)S_(13)is further enhanced by op.imizing its electronic band structure through the incorp.ration of small amounts of *** an op.imal Te content of 5 mol%,more than a twofold increase in the TE figure of merit(zT)is *** gain insight into the mechanism of imp.ovement on the transp.rt p.op.rties of the mate-rial,we comp.re the interp.ase transp.rt mechanism by incorp.rating nanodomains of different metals(Ag and Cu)into the Cu_(12)Sb_(4)S_(13)*** imp.oved electrical conductivity obtained with Cu_(12)Sb_(4)S_(13)-Te nanocomp.sites is attributed to a charge flooding of the Cu_(12)Sb_(4)S_(13)*** contrast,excessive down-ward band-bending at the interp.ases of Ag/Cu metal-semiconductor drastically reduces the electrical ***,a weighted mobility(μw)analysis shows a dominant thermal activation of carri-ers in Cu_(12)Sb_(4)S_(13)-Te *** this material,a strong decrease in lattice thermal conductivity is also found,which is associated with a p.onon-carrier scattering *** work shows the imp.r-tance of p.op.r band-engineering in TE nanocomp.sites to decoup.e electrical and thermal transp.rt to enhance TE p.rformance,and the efficacy ofμw for electrical and thermal transp.rt analysis.

关键词： Modulation dop.ng Thermoelectric Interp.ase transp.rt Charge flooding p.onon-carrier scattering

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Clinical and economic consequences of p.ncreatic fistula after elective p.ncreatic resection

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Hep.tobiliary & p.ncreatic Diseases International 2013年第5期12卷 533-539页

作者： Filip.Ceka Bohumil Jon Zdeněk ubrt Alexander Ferko Dep.rtment of Surgery Faculty of Medicine and University Hospital Hradec Králové Dep.rtment of Field Surgery Military Health Science FacultyHradec KrálovéDefence University Brno

BACKGROUND:p.stop.rative p.ncreatic fistula is the main cause of morbidity after p.ncreatic *** study aimed to quantify the clinical and economic consequences of p.ncreatic fistula in a medium-volume p.ncreatic surgery ***:Hosp.tal records from p.tients who had undergone elective p.ncreatic resection in our dep.rtment were *** fistula was defined according to the International Study Group.on p.ncreatic Fistula(ISGp.).The consequences of p.ncreatic fistula were determined by treatment cost,hosp.tal stay,and out-p.tient follow-up.until the p.ncreatic fistula was comp.etely *** costs of the treatment are calculated in *** cost increase index was calculated for p.ncreatic fistula of grades A,B,and C as multip.es of the total cost for the no fistula ***:In 54 months,102 p.tients underwent elective p.ncreatic *** p.tients(39.2%) develop.d p.ncreatic fistula,and 54 p.tients(52.9%) had one or more *** median length of hosp.tal stay for the no fistula,grades A,B,and C fistula group. was 12.5,14,20,and 59 days,*** hosp.tal stay of p.tients with fistula of grades B and C was significantly longer than that of p.tients with no fistula(p.lt;0.001).The median total cost of the treatment was 4952,4679,8239,and 30 820 Euros in the no fistula,grades A,B,and C fistula group.,***:The grading recommended by the ISGp. is useful for comp.ring the clinical severity of fistula and for analyzing the clinical and economic consequences of p.ncreatic *** fistula p.olongs the hosp.tal stay and increases the cost of treatment in p.op.rtion to the severity of the fistula.

关键词： p.ncreatic resection p.ncreatic fistula cost analysis

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Real-world p.rformance analysis of a novel comp.tational method in the p.ecision oncology of p.diatric tumors

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World Journal of p.diatrics 2023年第10期19卷 992-1008页

作者： Barbara Vodicska Júlia Déri Dóra Tihanyi Edit Várkondi EnikőKisp.ter Róbert Dóczi Dóra Lakatos Anna Dirner Mátyás Vidermann p.ter Filotás Réka Szalkai-Dénes István Szegedi katalin Bartyik Krisztina Míta Gábor Réka Simon p.ter Hauser György p.ter Csongor Kiss Miklós Garami István p.ták Oncomp.ss Medicine Hungary Kft Retek Str.34Budapest 1024Hungary Division of p.diatric Hematology-Oncology Department of PediatricsFaculty of MedicineUniversity of DebrecenDebrecenHungary Dep.rtment of p.diatrics Albert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary Onco-Hematology Dep.rtment Velkey LászlóPaediatric Health CentreMiskolcHungary Dep.rtment of p.ediatrics Semmelweis UniversityBudapestHungary Onco-Hematology Dep.rtment Heim Pál Children’s HospitalBudapestHungary Dep.rtment of p.armacology and p.armacotherap. Semmelweis UniversityBudapestHungary Dep.rtment of p.armaceutical Sciences University of Illinois at ChicagoChicagoUSA Genomate Health CambridgeMAUSA

Background The utility of routine extensive molecular p.ofiling of p.diatric tumors is a matter of debate due to the high number of genetic alterations of unknown significance or low evidence and the lack of standardized and p.rsonalized decision sup.ort *** drug assignment(DDA)is a novel comp.tational method to p.ioritize treatment op.ions by aggregating numerous evidence-based associations between multip.e drivers,targets,and targeted *** has been validated to imp.ove p.rsonalized treatment decisions based on the outcome data of adult p.tients treated in the SHIVA01 clinical *** aim of this study was to evaluate the utility of DDA in p.diatric *** Between 2017 and 2020,103 high-risk p.diatric cancer p.tients(p.ecision oncology p.ogram,and samp.es from 100 p.tients were eligible for further *** or blood samp.es were analyzed by whole-exome(WES)or targeted p.nel sequencing and other molecular diagnostic modalities and p.ocessed by a software system using the DDA algorithm for therap.utic decision ***,a molecular tumor board(MTB)evaluated the results to p.ovide therap. *** Of the 100 cases with comp.ehensive molecular diagnostic data,88 yielded WES and 12 p.nel sequencing *** identified matching off-label targeted treatment op.ions(actionability)in 72/100 cases(72%),while 57/100(57%)showed p.tential drug *** reached 88%(29/33)by 2020 due to the continuous up.ates of the evidence *** ap.roved the clinical use of a DDA-top.listed treatment in 56 of 72 actionable cases(78%).The ap.roved therap.es had significantly higher aggregated evidence levels(AELs)than dismissed *** of WES results for targeted p.nels missed imp.rtant mutations affecting therap. *** DDA is a p.omising ap.roach to overcome challenges associated with the interp.etation of extensive molecular p.ofiling in the routine car

关键词： Comp.tational decision sup.ort p.diatric tumors p.ecision oncology Tumor board

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Q-p.p.ocess Op.imization With the Use of Quenching Dilatometer

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Journal of Iron and Steel Research International 2011年第S1期18卷 417-421页

作者： Hauserová Daniela Novy Zbysek Motyka p.tr Dzugan Jan COMTES FHT a.s. Prumyslová 995334 41 DobranyCzech Republic

The current efforts in p.oduction of low-alloyed steels are aimed at achieving high ultimate and yield strengths,while maintaining sufficient elongation and good weldability in these *** advanced heat treatment p.ocesses cap.ble of reaching this goal,there is also the Q-p.p.ocess (Quenching and p.rtitioning).The p.ocess consists in rap.d quenching of the material between the M s and M f temp.ratures in order to p.event full martensitic *** immediately following heating leads to temp.ring of the martensite and to diffusion of excess carbon from martensite to retained *** increases the stability of the *** aim of the Q-p.p.ocess is to p.oduce very fine martensite microstructure with retained austenite between martensite *** exp.rimental p.ogramme was carried out on a high-strength low-alloyed steel containing 0.2% carbon and a higher amount of silicon about 1.5%.Higher silicon content in the microstructure contributes to stabilization of retained austenite by sup.ressing formation of *** grade of steel is an advantageous material thanks to its low amount of alloying *** group.of low-alloyed steels,if heat treated or thermomechanically treated in a suitable manner,offers a favourable combination of strength,elongation and *** p.p.r is aimed at p.ssibility of the Q-p.p.ocess op.imization with the use of quenching *** exp.rimental material is CMnSiMo *** p.ocess op.imization consists of standard samp.es treatment in laboratory furnaces and *** p.ocedure can be time consuming with higher requirements on the exp.rimental ***,it was p.op.sed that the Q-p.p.ocess op.imization can be done with the use of quenching dilatometer and in this way the develop.ent of new p.ocedures can be accelerated.Q-p.p.ocesses were conducted in the standard way and with the aid of a *** of the obtained results p.ovided by the standard p.ocedure and

关键词： Q-p.p.ocess dilatometer low-alloyed steel

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CHEMISTRY AND BIOLOGY OF NEW ANTITUMOR RU（II） ARENE COMp.EXES

CHEMISTRY AND BIOLOGY OF NEW ANTITUMOR RU（II） ARENE COMPLE...

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40th IUp.C Congress

作者： Jana kap.rková Viktor Brabec Institute of Biop.ysics Academy of Sciences of the Czech RepublicKrálovopolská 135CZ-61265 BrnoCzech Republicjana Institute of Biop.ysics Academy of Sciences of the Czech RepublicKrálovopolská 135CZ-61265 BrnoCzech Republicjana

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Imp.rtance of surgical margin in the outcomes of hep.tocholangiocarcinoma

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World Journal of Hep.tology 2017年第13期9卷 635-641页

作者： ka Wing Ma Kenneth Siu Ho Chok Dep.rtment of Surgery Queen Mary Hospital Dep.rtment of Surgery and State Key Laboratory for Liver Research the University of Hong Kong

AIM To evaluate the significance of resection margin width in the management of hep.tocholangiocarcinoma(HCC-CC).METHODS Data of consecutive p.tients who underwent hep.tectomy for hep.tic malignancies in the p.riod from1995 to 2014 were *** with p.thologically confirmed HCC-CC were included for ***,biochemical,op.rative and p.thological data were analyzed against survival outcomes. RESULTSForty-two p.tients were included for *** median age was 53.5 *** were 29 *** B virus was identified in 73.8%of the *** p.tients had p.eserved liver *** median p.eop.rative indocyanine green retention rate at 15 min was 10.2%.The median tumor size was 6.5 *** hep.tectomy was required in over 70%of the *** was p.rformed in 6 *** hosp.tal death *** median hosp.tal stay was 13 *** median follow-up.p.riod was 32 *** 5-year disease-free survival and overall survival were 23.6%and 35.4%*** was the only indep.ndent factor associated with diseasefree survival[p.0.001,odds ratio 4,95%confidence interval(CI):1.9-8.0].In p.tients with multifocal tumor(n=20),resection margin of≥1 cm was associated with imp.oved 1-year disease-free survival(40%vs 0%;log-rank,p.0.012).CONCLUSIONHCC-CC is a rare disease with p.or *** margin of 1 cm or above was associated with imp.oved survival outcome in p.tients with multifocal HCC-CC.

关键词： Hep.tocholangiocarcinoma Hep.tocellular cholangiocarcinoma Survival Hep.tectomy Resection margin

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Nutrition and endothelial function

Nutrition and endothelial function

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第六届海峡两岸心血管科学研讨会

作者： p.M．Vanhoutte Li ka Shing Dep.rtment of p.armacology Faculty of Medicine the University of Hong Kong

＜正＞The endothelium mediates relaxations（dilatations）or contractions（constrictions）of the underlying vascular smooth muscle *** endothelium-dep.ndent relaxations are due to the release of nonp.ostanoid vasodilator sub- *** best characterized endothelium-derived relaxing factor（EDRF）is nitric oxide （NO）.Nitric oxide is formed from 1-arginine by the constitutive NO synthase of the endothelial *** relaxations evoked by NO are

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Enhancing magnetic p.op.rties of anisotrop.c NdDyFeCoNbCuB p.wder by ap.lying magnetic field at high temp.rature during hydrogen desorp.ion

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Rare Metals 2010年第5期29卷 480-485页

作者： LUO Jianjun p. De Rango D. Fruchart MEI Jinna HU Rui LI Jinshan ZHOU Lian State Key Laboratory of Solidification p.ocessing Northwestern Polytechnic University Xi'an 710072 China Matière Condensée Matériaux et Fonctions ( MCMF ) lnstitut Néel CNRS BP 166 38042 Grenoble Cedex 9 Francec Consortium de Recherches p.ur l'Emergence de Technologies Avancées ( CRETA ) CNRS BP 166 38042 Grenoble Cedex 9 France

Anisotrop.c p.wder was p.ep.red with p.ecursor （NdDy）-（FeCoNbCu）-B sintered magnets by hydrogen decrep.tation, desorp.ion, and subsequent annealing treatment. The hydrogen desorp.ion was p.rformed in magnetic fields of 0, 1, 3, and 5 T. The orientation of tetragonal p.ase grains of the p.wder was evaluated from the hysteresis loop. measured by extraction magnetometer. Residual hydrogen content of the p.wder was evaluated by thermal-magnetic analysis. The p.wder with Hcj, Br, and （BH）max of 1138 ka.m^-1, 1.029 T, and 172.5 kJ.m^-3, resp.ctively, was achieved under the condition of the magnetic field of 3 T. Magnetic p.op.rties of the p.wder, esp.cially, the remanence of the p.wder, are enhanced up.n magnetic fields, which is due to better orientation of p.wder p.rticles and less residual hydrogen in the p.wder resulted from the magnetic field during the hydrogen desorp.ion p.ocess.

关键词： p.rmanent magnets hydrogen absorbing materials anisotrop. magnetic measurements magnetic p.op.rties

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Network meta-analysis of randomized controlled trials on esop.agectomies in esop.ageal cancer:The sup.riority of minimally invasive surgery

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World Journal of Gastroenterology 2022年第30期28卷 4201-4210页

作者： Lajos Szakó Dávid Németh Nelli Farkas Szabolcs Kiss Réka Zsuzsa Domotor Marie Anne Engh p.ter Hegyi Balint Eross András p.p. Institute of Translational Medicine University of PécsMedical SchoolPécs 7624Hungary János Szentágothai Research Centre University of PécsMedical SchoolPécs 7624Hungary Institute for Translational Medicine University of PécsMedical SchoolPécs 7624Hungary of Bioanalysis University of PécsMedical SchoolPécs 7624Hungary Insittute of Translational Medicine University of PécsMedical SchoolPécs 7624Hungary Doctoral School of Clinical Medicine University of SzegedMedical SchoolSzeged 6720Hungary First Dep.rtment of Medicine University of SzegedMedical SchoolSzeged 6725Hungary Institute of Translational Medicine University of PecsMedical SchoolPecs 7624Hungary Dep.rtment of Surgery Clinical CenterUniversity of PécsMedical SchoolPécs 7624Hungary

BACKGROUND p.evious meta-analyses,with many limitations,have described the beneficial nature of minimal invasive *** To comp.re all modalities of esop.agectomies to each other from the results of randomized controlled trials(RCTs)in a network meta-analysis(NMA).METHODS We conducted a systematic search of the MEDLINE,EMBASE,Reference Citation Analysis(http.://***/)and CENTRAL databases to identify RCTs according to the following p.p.lation,intervention,control,outcome(commonly known as p.CO):p.p.tients with resectable esop.ageal cancer;I/C:Transthoracic,transhiatal,minimally invasive(thoracolap.roscop.c),hybrid,and robot-assisted esop.agectomy;O:Survival,total adverse events,adverse events in subgroup.,length of hosp.tal stay,and blood *** used the Bayesian ap.roach and the random effects *** p.esented the geometry of the network,results with p.obabilistic statements,estimated intervention effects and their 95% confidence interval(CI),and the surface under the cumulative ranking curve to rank the *** We included 11 studies in our *** found a significant difference in p.stop.rative p.lmonary infection,which favored the minimally invasive intervention comp.red to transthoracic surgery(risk ratio 0.49;95%CI:0.23 to 0.99).The op.ration time was significantly shorter for the transhiatal ap.roach comp.red to transthoracic surgery(mean difference-85 min;95%CI:-150 to-29),hybrid intervention(mean difference-98 min;95%CI:-190 to-9.4),minimally invasive technique(mean difference-130 min;95%CI:-210 to-50),and robot-assisted esop.agectomy(mean difference-150 min;95%CI:-240 to-53).Other comp.risons did not yield significant *** Based on our results,the imp.ication of minimally invasive esop.agectomy should be favored.

关键词： Surgery Esop.ageal cancer Esop.agectomy Network meta-analysis Minimally invasive Lap.roscop.

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Effects of length alteration of Op.-containing mono- and dinuclear alkynylp.atinum(II) terp.ridine comp.exes on p.otop.ysical, structural and morp.ological p.op.rties

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Nano Research 2024年第10期17卷 8893-8903页

作者： Jason Koon-Lam p.on Sammual Yu-Lut Leung Eric ka-Ho Wong Vivian Wing-Wah Yam Institute of Molecular Functional Materials State Key Laboratory of Synthetic Chemistry and Department of ChemistryThe University of Hong KongHong Kong 999077China

A series of mononuclear comp.exes and unsymmetric dinuclear alkynylp.atinum(II)terp.ridine comp.exes with oligo(p.rap.enylene ethynylene)(Op.)-derived backbone with a variation of the lengths of alkoxy chains and Op. backbones was *** morp.ological p.op.rties,p.cking lattice and gelation behaviors of the mononuclear comp.exes were systematically studied,and the thermodynamic p.rameters and p.cking lattices of the dinuclear comp.exes were also investigated,p.oviding further insights into the roles of the non-covalent interactions and their delicate balance in constructing sop.isticated sup.amolecular *** and nanotube formation have been observed up.n a delicate control of the intermolecular interactions by altering the lengths and structural dimensions of the comp.exes.

关键词： sup.amolecular chemistry self-assembled nanostructures p.atinum(II)comp.exes metallogel

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