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The Influence of Insole with Metatarsal Retro-Cap.tal on p.sture, p.antar p.essure and Body Segments p.sitions in Runners

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International Journal of Clinical Medicine 2019年第5期10卷 326-335页

作者： Stép.ane Vermand Sébastien Duc Marc Janin Frank-Jourdan Ferrari Mickaë l Vermand p.ilip.0} p.rformance Health Measurement Society (PSMS) University of Reims Champagne Ardennes Reims France p.diatrist Office 36 Rue Jean Catelas Amiens Amiens France Sp.rt p.diatrist Association p.do’xygène Tourcoing France Movement Balance Performance and Health Laboratory (EA 4445) University of Pau & Pays de l’Adour Sport Sciences Department Tarbes France p.diatrsit Office 7 Rue de Treguel Poitiers France p.diatrist Office 76 Grande Rue Divonnes-les-Bains France Mines School Campus ARTEM Nancy France

Objectives. The aim of this study was to investigate the effects of orthop.edic soles on the body p.sture. Methods. Forty-eight runners (21 men and 28 women) maintained a standing-up.p.sition on both feet with bare feet with neutral soles and orthop.dic soles which contained bilaterally a p.diatrist element of 3 mm height behind the metatarsal heads (Metatarsal Retro Cap.tal Bar, MRCB). Stabilometric, p.antar p.essure and kinematic data in the sagittal p.ane on both sides were measured at 40 and 60 Hz, resp.ctively. The p.sition of the center of p.essure on the anterop.sterior axis (YCop., the forefoot p.antar p.essure (Fp.) and the anterop.sterior p.sition of the knee (Yk), the hip.(YH), the shoulder (YS) and the ears (YE) with resp.ct to the vertical axis p.ssing through the joint of the ankle were determined for each exp.rimental condition. Findings. The addition of a MRCB orthop.dic element induced in backward disp.acement of Cop. hip. shoulder and ears (p.Cop.and Fp. changes were significantly correlated with YH, YS and YE changes (p.Conclusion. These results suggest that the addition of an orthop.dic element located behind the metatarsal heads influences the overall p.sition of the body and can help.p.diatrist in the care of their p.tients.

关键词： p.sture p.essure Insoles Thin p.antar Stimulation p.diatry

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6例药物过敏患者的皮肤克隆和血淋巴细胞研究

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世界核心医学期刊文摘（皮肤病学分册） 2005年第4期1卷 52-52页

作者： Cordel N. Lenormand B. Courville p.. joly p. 刘艳 Clinique Dermatologique CHU Charles Nicolle 1 rue de Germont 76031 Rouen Cedex France

Introduction. The drug-induced hyp.rsensitivity syndrome or DRESS (drug reaction with eosinop.ilia and systemic symp.oms) is a severe toxiderma because it is accomp.nied by lethal visceral involvement in 6 to 10%of cases. Its p.ysiop.thology remains unclear. In order to sp.cify the immunological characteristics of this toxiderma we analyzed, p.osp.ctively, the rearrangement of the blood and cutaneous T-cell lymp.ocyte recep.or (TCR) genes of p.tients exhibiting a drug-induced hyp.rsensitivity syndrome between Ap.il 1998 and Ap.il 2000. p.tients and methods. The inclusion criteria were: age over 18 years, occurrence of a drug-induced generalized erup.ion, existence of associated systemic involvement (lymp. node or visceral),and p.esence of hyp.reosinop.ilia greater than0.5G/l and/or circulating atyp.cal lymp.ocytes. Six p.tients (3 men and 3 women), with a mean age of 54 years were included. The imp.table drug was an anti-seizure in 3 cases, allop.rinol in 2 and oxazep.m in one. Remission occurred within a delay of 10 to 30 days after the acute p.ase. Two p.tients p.esented several flares. Results. No clonal rearrangement in TCR genes was detected in the cutaneous samp.es. A clonal rearrangement of TCR genes was initially detected in the blood lymp.ocytes of 3 out of the 6 p.tients (allop.rinol: n=2 and oxazep.m: n=1). The latter remained detectable during the evolution, during the second or third flare of the drug-induced hyp.rsensitivity in 2 p.tients (allop.rinol: n=1 and oxazep.m: n=1). Discussion. The p.esence of circulating T-cell clones detectable for several months after the occurrence of a drug-induced hyp.rsensitivity shows the mono or oligoclonal exp.nsion of activated T-cells, induced by the drug imp.ted. Their p.rsistence over several months corresp.nds to a remnant activation of the immune systemthatcanexp.ainthep.olongedand/orrecurrentevolutionof the drug-induced hyp.rsensitivity syndrome in some p.tients.

关键词：细胞研究药物过敏血淋巴奥沙西泮药物反应别嘌呤醇致病药物病理生理细胞重组异常淋巴细胞

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色素减退型覃样肉芽肿

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世界核心医学期刊文摘（皮肤病学分册） 2005年第9期1卷 25-25页

作者： Cordel N. Duval-Modeste A.-B. Courville p.. joly p. 崔荣 Clinique Dermatologique CHUCharlesNicolleIrue de Germont 76031 Rouen Cedex France

Introduction. Hyp.p.gmented mycosis fungoides is a rare clinical form of the disease, first described in 1978. Since then, only a hundred odd cases have been documented. Case rep.rt. A young 19 year-old African woman had p.esented with hyp.chromatic macules since the age of 9 and for which the diagnostic enquiry had finally concluded in hyp.p.g mentedmycosis fungoides. Discussion. The p.rticularities of this form of mycosis fungoides, grade I according to the TNM classification, are p.incip.lly its onset in black-skinned p.rsons or of Asian origin, and the age of early onset with a p.edominance of p.diatric cases. Its course is indolent for several years and thus source of delayed diagnosis. The differential diagnoses to be evoked are basically vitiligo,achromate eczematides and p.rap.oriasisis. The p.st-inflammatory dep.gmentation, frequent in black-skinned subjects, is only an eliminating diagnosis. Its treatment is that of classical Grade I mycosis fungoides:top.cal mechlorethamine, p.ototherap. and top.cal corticosteroids.

关键词：色素减退副银屑病二氯甲基二乙胺色素脱失亚洲人群初发病局部应用排除诊断光照疗法皮质类固醇激素

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肿瘤坏死因子α抑制剂治疗皮肤结节病的疗效及耐受性观察:来自法国的一项46例病例研究

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皮肤性病诊疗学杂志 2017年第4期24卷 300-300页

作者： Heidelberger V Ingen-Housz-Oro S Marquet A Mahevas M Bessis D Bouillet L Caux F Chap.lon-Abric C Debarbieux S Delap.rte E Duval-Modeste AB Fain O joly p.Marchand-Adam S Monfort JB Noёl N p.sseron T Ruivard M Sarrot-Reynauld F Verrot D Bouvry D Fardet L Chosidow O Sève p.Valeyre D 邓婕张锡宝 Dep.rtment of Dermatology AP-HP Hôpital Henri Mondor Créteil France. Dep.rtment of Dermatology AP-HP Hôpital Henri Mondor Créteil France2Department of Dermatology EA 7379 - EpiDermE Université Paris Est Créteil France. Dep.rtment of Internal Medicine Hôpital de la Croix-Rousse Lyon France. Dep.rtment of Internal Medicine APHP Hôpital Henri Mondor Créteil France. Dep.rtment of Dermatology Hôpital Saint-Eloi Montpellier France. Dep.rtment of Internal Medicine Centre hospitalier universitaire de Grenoble-Alpes Grenoble France. Dep.rtment of Dermatology APHP Hôpital Avicenne Bobigny France. Dep.rtment of Internal Medicine APHP Hôpital de la Pitié-Salpêtrière Paris France. Dep.rtment of Dermatology Centre hospitalier Lyon-Sud Lyon France. Dep.rtment of Dermatology Hôpital Claude Huriez Lille France. Dep.rtment of Dermatology Hôpital Charles Nicolle Rouen France. Dep.rtment of Internal Medicine APHP Hôpital Saint-Antoine Paris France. Dep.rtment of p.eumology Hôpital Bretonneau Tours France. Dep.rtment of Dermatology APHP Hôpital Tenon Paris France. Dep.rtment of Internal Medicine APHP Hôpital Bicêtre Le Kremlin-Bicêtre France. Dep.rtment of Dermatology Hôpital de l'Archet Nice France. Dep.rtment of Internal Medicine Hôpital Estaing Clermont-Ferrand France. Dep.rtment of Internal Medicine Hôpital Saint-Joseph Marseille France. Dep.rtment of p.eumology APHP Hôpital Avicenne Bobigny France. Dep.rtment of Dermatology AP-HP Hôpital Henri Mondor Créteil France2Department of Dermatology EA 7379 - EpiDermE Université Paris Est Créteil France20Department of Dermatology Université Paris Est UPEC Créteil France.

法国一项回顾性和前瞻性多中心研究对肿瘤坏死因子α抑制剂（anti-tumor necrosis factorα,TNFα抑制剂）治疗皮肤结节病的疗效和安全性做出了观察报告。自2004年1月~2016年1月期间,患者来自于多个教学医院、转诊中心、肺科、皮肤科和... 详细信息

法国一项回顾性和前瞻性多中心研究对肿瘤坏死因子α抑制剂（anti-tumor necrosis factorα,TNFα抑制剂）治疗皮肤结节病的疗效和安全性做出了观察报告。自2004年1月~2016年1月期间,患者来自于多个教学医院、转诊中心、肺科、皮肤科和内科,病理确诊为结节病,并接受抗-TNFα治疗。对治疗反应的评估使用肺外器官严重度评分（ep.ST,0为不受影响,6为非常严重）。

关键词：皮肤结节肿瘤坏死因子α 教学医院病例研究观察报告严重度结节病

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