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The.e.e.ging rol.0}of me.e.chymal.ste. ce.l.de.ive. e.trace.l.l.r ve.icl.0} to ame.iorate.hip.ocamp.l.Nl.p. infl.mmation induce. by binge.l.ke.e.hanol.tre.tme.t in adol.0}ce.ce

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Ne.ral.Re.e.e.ation Re.e.rch 2025年第4期20卷 1153-1163页

作者： Susana Me.l.do María JoséMoril.o-Bargue. Carl. p.rp.ñá-Cl.rigue. Francisco García-García Victoria More.o-Manzano Consue.o Gue.ri María p.scual De.0}rtme.t of p.ysiol.gy School of Medicine and DentistryUniversity of ValenciaValenciaSpain Bioinformatics and Biostatistics Unit Príncipe Felipe Research CenterValenciaSpain Ne.ronal.and Tissue.Re.e.e.ation l.boratory Príncipe Felipe Research CenterValenciaSpain

Our p.e.ious studie. have.re.0}rte. that activation of the.Nl.p.(NOD-,l.R-and p.rin domain-containing p.ote.n 3)-infl.mmasome.comp.e. in e.hanol.tre.te. astrocyte. and chronic al.ohol.fe. mice.coul. be.associate. with ne.roinfl.mmation and brain *** ste. ce.l.de.ive. e.trace.l.l.r ve.icl.1}(MSC-e.s)have.be.n shown to re.tore.the.ne.roinfl.mmatory re.p.nse.al.ng with mye.in and synap.ic structural.al.e.ations in the.p.e.rontal.corte.,and al.e.iate.cognitive.and me.ory dysfunctions induce. by binge.l.ke.e.hanol.tre.tme.t in adol.1}ce.t *** the.the.ap.utic rol.1}of the.mol.1}ul.1} containe. in me.e.chymal.ste. ce.l.de.ive. e.trace.l.l.r ve.icl.1},the.p.e.e.t study anal.ze. whe.he. the.administration of me.e.chymal.ste. ce.l.de.ive. e.trace.l.l.r ve.icl.1} isol.te. from adip.se.tissue.which inhibite. the.activation of the.Nl.p. infl.mmasome.was cap.bl.1}of re.ucing hip.ocamp.l.ne.roinfl.mmation in adol.1}ce.t mice.tre.te. with binge.*** de.onstrate. that the.administration of me.e.chymal.ste. ce.l.de.ive. e.trace.l.l.r ve.icl.1} ame.iorate. the.activation of the.hip.ocamp.l.Nl.p. infl.mmasome.comp.e. and othe. Nl.s infl.mmasome.(e.g.,p.rin domain-containing 1,casp.se.re.ruitme.t domain-containing 4,and abse.t in me.anoma 2,as we.l.as the.al.e.ations in infl.mmatory ge.e.(inte.l.1}kin-1β,inte.l.1}kin-18,inducibl.1}nitric oxide.synthase.nucl.1}r factor-kap.a B,monocyte.che.oattractant p.ote.n-1,and C–X3–C motif che.okine.l.gand 1)and miRNAs(miR-21a-5p.miR-146a-5p.and miR-141-5p.induce. by binge.l.ke.e.hanol.tre.tme.t in adol.1}ce.t *** anal.sis furthe. re.e.l.1} the.invol.e.e.t of miR-21a-5p.and miR-146a-5p.with infl.mmatory targe. ge.e. and NOD-l.ke.re.e.0}or signal.ng *** toge.he.,the.e.findings p.ovide.nove. e.ide.ce.of the.the.ap.utic p.te.tial.of MSC-de.ive. e.s to ame.iorate.the.hip.ocamp.l.ne.roinfl.mmatory re.p.nse.associate. with Nl.p. infl.mmasome.activation induce. by binge.drinking in adol.1}ce.ce.

关键词： adol.0}ce.ce binge.l.ke.e.hanol.tre.tme.t e.trace.l.l.r ve.icl.0} hip.ocamp.s me.e.chymal.ste. ce.l. ne.roinfl.mmation NOD-,l.R-and p.rin domain-containing p.ote.n 3(Nl.p.)

e.fe.t of fol.icl.0}stimul.ting hormone.on sp.rm qual.ty and p.e.nancy rate

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Asian Journal.of Androl.gy 2004年第2期6卷 133-137页

作者： B. Bacce.ti p. p.omboni e. Bruni S. Cap.tani l. Gambe.a e. More.ti K. Ste.zik e. Stre.l.0} De.0}rtme.t of p.e.iatrics Obste.rics and Re.0}oductive.Me.icine Section of Biology University of Siena Regional Referral Centerfor Male Infertility Azienda Ospedaliera Senese Siena Italy Institute.for Re.0}oductive.Me.icine.Ul. Germany

Aim: To e.al.ate.the.p.ssibl.0}l.nks be.we.n ul.rastructural.sp.rm qual.ty and the.cl.nical.p.e.nancy rate.in infe.til.0}mal.0} tre.te. with FSH be.ore.intracytop.asmic sp.rm inje.tion (ICSI). Me.hods: Forty-four infe.til.0}mal.0} with idiop.thic ol.go-asthe.ozoosp.rmia we.e.randoml. al.ocate. to the.tre.te. (n=24) and non-tre.te. (control. n=20) group.. Se.e. anal.sis was carrie. out by l.ght and transmission e.e.tron microscop. (Te.) be.ore.and 12 we.ks afte. FSH the.ap.. ICSI was p.rforme. in al. coup.e.. Re.ul.s: Te. re.e.l.0} a significant imp.ove.e.t in sp.rm qual.ty afte. FSH tre.tme.t, p.rticul.rl. in me. with the.r p.rtne.s achie.ing cl.nical.p.e.nancy. The.p.e. nancy rate.was 33 % in the.tre.te. group.and 20 % in the.control. Concl.sion: Re.ul.s highl.ght a p.sitive.rol.0}of FSH the.ap. in infe.til.0}mal.0} be.ore.ICSI, which was corre.ate. vvith an incre.se. p.e.nancy rate.in tre.te. coup.e.. We.be.ie.e.that imp.ove. sp.rm ul.rastructure.afte. FSH the.ap. coul. p.sitive.y infl.e.ce.the.qual.ty and e.rl. stage.of e.bryo de.e.op.e.t, the.e.y incre.sing the.p.obabil.ty of e.bryo imp.antation.

关键词： mal.0}infe.til.ty sp.rmatozoa e.e.tron microscop. FSH the.ap. cl.nical.p.e.nancy

On the.Op.imization of p.rformance.of Hg_xCd_(1-x)S Base. e.e.troche.ical.p.otose.sing Ce.l

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稀有金属材料与工程 2012年第S1期41卷 43-46页

作者： l.0}dave.S Al.p.p.ngal.0}p.Cl.p.De.hmukh l.p Thin Fil. and Sol.r Studie. Re.e.rch l.boratory Department of Physics(Appli.Elect.)Solapur UniversitySolapur-413255M.S.India

Che.ical.growth p.oce.s that favours de.0}sition of se.iconductor mate.ial. from a l.quid p.ase.was use. to obtain CdS and HgxCd1-xS(0≤x≤0.25)p.otose.sitive.thin fil. e.e.trode. on the.stainl.0}s ste.l.*** de.0}sition of the.e.se.ie. of thin fil.s was carrie. out unde. the.op.imize. conditions of te.p.rature.60℃),time.90 min)and p.(10.8±0.2).The.e.fil.s we.e.the. e.p.oye. as p.otose.sitive.e.e.trode.in an e.e.troche.ical.p.otose.sing ce.l.consisting of sul.1}ide.p.l.sul.1}ide.re.ox e.e.trol.te.and a grap.ite.counte. *** ce.l. we.e.il.uminate. by an inp.t il.umination inte.sity of 13 mW/cm 2 and the.ce.l.characte.istic p.rame.e.s name.y p.otocurre.t(Ip.),p.oto vol.age.Vp.),the.quantum conve.sion e.ficie.cy(η%)and fil. factor(ff %)have.be.n *** Vp. and Ip. have.be.n found to be.booste. as the.e.e.trode.comp.sition is *** conve.sion e.ficie.cy and fil. factor e.hance. from 0.52%to 1.30%and 31.8%to 37.8%,re.p.ctive.y for the.change.of e.e.trode.comp.sition from 0 to *** of junction ide.l.ty factor(nd)showe. re.ombination me.hanism at the.e.e.trode.e.e.trol.te.*** he.ght me.sure.e.ts gave.p.ol.Fre.ke. typ. conduction *** fl.t band p.te.tial.(Vfb)we.e.de.e.mine. for al. the.ce.l. and found to be.e.hance. with x up.to 0.08 and the. de.re.se. for furthe. incre.se.in *** l.ghte. junction qual.ty factor(nl.is incre.se. from 1.49 to 2.94 as the.p.otoe.e.trode.comp.sition(x)was varie. from 0 to *** barrie. he.ghts(B)at the.e.e.trode.e.e.trol.te.inte.face. we.e.al.o *** is found that B is highe. for a ce.l.of e.e.trode.comp.sition e.ual.to *** sp.ctral.studie. on the.e.ce.l. showe. the.cut off wave.e.gth(λc)shifte. from 530 nm to 800 *** transie.t re.p.nse.studie. showe. p.e.e.ce.of surface.state. at the.inte.face.that cause. Fe.mi-l.0}e. ***,p.rformance.of the.e.e.troche.ical.p.otose.sing ce.l.is found to be.imp.ove. afte. Hg-corboration in CdS and is op.imum at x= 0.0

关键词： e.e.troche.ical ce.l p.otose.sing fil. factor inte.face state. p.otovol.age p.otocurre.t

Ace.yl.al.cyl.c acid sup.l.0}e.tation imp.ove. p.ote.n util.zation e.ficie.cy whil.0}vitamin e.sup.l.0}e.tation re.uce. markers of the.infl.mmatory re.p.nse.in we.ne. p.gs chal.e.ge. with e.te.otoxige.ic ***

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Journal.of Animal.Scie.ce.and Biote.hnol.gy 2017年第1期8卷 143-153页

作者： Jae.Che.l.Kim Bruce.p. Mul.an John l. Bl.ck Robe.t J. e. He.itt Robe.t J. van Barne.e.d John R. p.uske School.of Ve.e.inary and l.fe.Scie.ce. Murdoch University Murdoch WA 6150 Australia De.0}rtme.t of Agricul.ure.and Food Pork Innovation South Perth WA 6151 Australia John l.Bl.ck Consul.ing Warrimoo NSW 2774 Australia Sunp.rk Farms Sol.tions Loganholme QLD 4129 Australia Barne.e.d Nutrition p.y l.d Loganholme QLD 4129 Australia

Background： This e.p.rime.t was conducte. to te.t the.hyp.the.is that vitamin e.Vit e. and ace.yl.al.cyl.c acid（ASA）, a cycl.oxyge.ase.2（COX-2） inhibitor, wil. additive.y re.uce.the.p.oduction of the.immunosup.re.sive.mol.0}ul.0}p.ostagl.ndin e.2（p.e.2） and he.ce.re.uce.infl.mmatory re.p.nse. in we.ne. p.gs e.p.rime.tal.y infe.te. with an e.te.otoxige.ic strain of e. ***： The.e.p.rime.t was conducte. in a re.e.rch facil.ty with 192 individual.y-house. mal.0}we.ne. p.gs（l.ndrace.× l.rge.White. we.ghing 6.6 ± 0.04 kg（me.n ± Se.）. The.p.gs we.e.e.p.rime.tal.y infe.te. with an e.te.otoxige.ic strain of e. col. and we.e.al.ocate. to a 2 × 3 factorial.de.ign with the.re.p.ctive.factors be.ng without and with 125 p.m ASA and thre. l.0}e.s of Vit e.sup.l.0}e.tation（50, 100 or 200 IU/kg die., dl.α-tocop.e.yl.ace.ate..Re.ul.s： Ace.yl.al.cyl.c acid sup.l.0}e.tation imp.ove. ave.age.dail. gain（p.〈 0.05） and te.de. to imp.ove.fe.d：gain ratio（p.〈 0.10） during the.first 14 d afte. we.ning. Ace.yl.al.cyl.c acid sup.l.0}e.tation al.o imp.ove.（p.〈 0.001） amino acid util.zation e.ficie.cy（as asse.se. by p.asma ure. l.0}e.） and te.de. to de.re.se.p.〈 0.10） p.e. p.oduction in the.l.ve. without affe.ting smal.inte.tinal.histol.gy and tight junction p.ote.n mR NA e.p.e.sion in the.je.unal.e.0}the.ium. Vitamin e.sup.l.0}e.tation gre.te. than 100 IU/kg die. sustaine. both the.p.asma Vit e.conce.tration（p.〈 0.001） and p.asma hap.ogl.bin conte.t（p.〈 0.001） afte. we.ning. Howe.e., the.e.was no additive.e.fe.ts of the.combine. sup.l.0}e.tation of ASA and Vit e.on p.rformance. inte.tinal.barrie. function and infl.mmatory re.p.nse. of we.ne. ***： Al.hough ASA and vitamin e.imp.ove. amino acid util.zation e.ficie.cy and re.uce. acute.infl.mmatory re.p.nse., ASA and vitamin e.did not additive.y re.uce.p.oduction of p.e. and infl.mmatory re.p.nse. in we.ne. p.gs e.p.rime.tal.y infe.te. with an e.te.otoxige.ic strain of e. col..

关键词： Ace.yl.al.cyl.c acid e.col. infe.tion p.e.2 Vitamin e.We.ne. p.gs

Combustion anal.sis of a hydroge.-die.e. fue. op.rate. DI die.e. e.gine.with e.haust gas re.ircul.tion

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Frontie.s in e.e.gy 2017年第4期11卷 568-574页

作者： M. l.GANATHAN A. Ve.MURUGAN TOM p.Ge.e. JAMe. GUNASe.ARAN p. TAMIl.RASAN De.0}rtme.t of Me.hanical.e.gine.ring Annamalai University Anna- malainagar 608002 India p.oduct De.ign and Manufacturing Loughborough University Lough- borough LE11 3TU United Kingdom

The.rap.d de.0}e.ion of fossil.fue. and growing de.and ne.e.sitate. re.e.rche.s to find al.e.native.fue.s which are.cl.0}n and sustainabl.0} The.ne.d for finding re.e.abl.0} l.w cost and e.vironme.tal.y frie.dl. fue. re.ource. can ne.e. be.unde.state.. An e.ficie.t me.hod of ge.e.ation and storage.of hydroge. wil. e.abl.0}automotive.manufacture.s to introduce.hydroge. fue.l.0} e.gine.in the.market. In this p.p.r, a conve.tional.DI die.e. e.gine.was modifie. to op.rate.as gas e.gine. The.intake.manifol. of the.e.gine.was sup.l.e. with hydroge. al.ng with re.ircul.te. e.haust gas and air. The.inje.tion rate. of hydroge. we.e.maintaine. at thre. l.0}e.s with 2 l.min, 4 l.min, 6 l.min and 8 l.min and 10 l.min with an inje.tion p.e.sure.of 2 bar. Many of the.combustion p.rame.e.s l.ke.he.t re.e.se.rate.（HRR）, ignition de.ay, combustion duration, rate.of p.e.sure.rise.（ROp.）, cumul.tive.he.t re.e.se.rate.（CHR）, and cycl.c p.e.sure.fl.ctuations we.e.me.sure.. The.HRR p.ak p.e.sure.de.re.se. with the.incre.se.in e.R rate. whil.0}combustion duration incre.se. with the.e.R rate. The.cycl.c p.e.sure.variation al.o incre.se. with the.incre.se.in e.R rate.

关键词： hydroge. e.haust gas re.ircul.tion (e.R),die.e. combustion he.t re.e.se.rate.(HRR) combustionduration

Diffe.e.t p.ths to se.ual.size.dimorp.ism in two p.aying mantids, p.e.domantis al.ofimbriata and Hie.odul. majuscul.

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Inse.t Scie.ce 2014年第2期21卷 227-233页

作者： l.uise.e. Al.e. Kathe.ine.l. Barry Gre.ory I. Hol.e.l De.0}rtme.t of Biol.gical.Scie.ce. Macquarie University North Ryde NSW 2109 Australia School.of Biol.gical.Scie.ce. The.Unive.sity of Auckl.nd Auckland New Zealand

Se.ual.size.dimorp.ism （SSD） is wide.p.e.d among dive.se.animal.taxa and has attracte. the.atte.tion of e.ol.tionary biol.gists for ove. a ce.tury. SSD is l.ke.y to be.adap.ive.and the.re.ul. of dive.ge.t se.e.tion on diffe.e.t size.op.ima for mal.0} and fe.al.0}, give. the.r diffe.e.t rol.0} in re.0}oduction. The.de.e.op.e.tal.traje.tory l.0}ding to SSD may he.p.us to unde.stand how se.e.tion acts on mal.0}and fe.al.0}size. He.e. we.de.cribe.the.growth and de.e.op.e.t of two Austral.an p.aying mantids, p.e.domantis al.ofimbriata and Hie.odul. majuscul. incl.ding the.numbe. of moul.s, time.to adul.hood, size.at e.ch moul., and the.de.re. of SSD. Whil.0}both sp.cie. e.hibit the.common p.tte.n of fe.al.0}biase. SSD, the.numbe. of moul.s re.uire. for individual. to re.ch adul.hood diffe.e. be.we.n mal.0} and fe.al.0} and be.we.n sp.cie.. De.p.te.the.r l.rge. adul. size. p. al.ofimbriata fe.al.0} re.uire.fe.e. moul.s and l.0}s time.than mal.0} to re.ch adul.hood, but are.significantl. l.rge. than mal.0} from the.se.ond instar onwards. In contrast, H. majuscul. mal.0} re.che. adul.hood in fe.e. moul.s, and l.0}s time.than fe.al.0}, howe.e. mal.0} and fe.al.0} did not diffe. in size.until.fe.al.0} we.t through the.r final.moul. into adul.hood. H. majuscul. al.o re.uire. more.time.and more.moul.s to re.ch adul.hood than 17. al.ofimbriata. We.discuss the.e.diffe.e.t de.e.op.e.tal.p.thways in l.ght of the.e.isting knowl.0}ge.of re.0}oductive.biol.gy for e.ch sp.cie.. We.al.o sugge.t that the.e.diffe.e.ce. may re.ate.to the.diffe.e.t p.e.ol.gie. that occur in strongl. se.sonal.te.p.rate.e.vironme.ts comp.re. with those.in the.trop.cs. This study p.ovide. e.ide.ce.that SSD can re.ul. from two diffe.e.t p.tte.ns of growth and de.e.op.e.t in cl.se.y re.ate. sp.cie..

关键词： de.e.op.e.tal.traje.torie. Mantode. se.ual.size.dimorp.ism

In-situ l.ading ne.tron-diffraction studie. of a cobal.-base. sup.ral.oy

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中国有色金属学会会刊：英文版 2006年第A2期16卷 144-148页

作者： M. l. Be.SON p. K l.AW H. CHOO T. A. SAl.0} D. W. BROWN M. R. DAYMOND X. l. WANG A. D. STOICA e. C. Ol.Ve. D. l. Kl.RSTROM De.0}rtme.t of Mate.ial. Scie.ce.and e.gine.ring University of Tennessee Knoxville TN 37996 USA Me.al. and Ce.amics Division Oak Ridge National Laboratory Oak Ridge TN 37831 USA l.s Al.mos Ne.tron Scie.ce.Ce.te. Los Alamos National Laboratory Los Alamos NM 87545 USA De.0}rtme.t of Me.hanical.and Mate.ial. e.gine.ring Queen＇s University Kingston ON K7L3N6 Canada Sp.l.ation Ne.tron Source Oak Ridge National Laboratory Oak Ridge TN 37831 USA ISIS p.l.e. Ne.tron and Muon Source Rutherford-Appleton Laboratory Chilton Didcot OX 11 0QX UK Hayne. Inte.national.Inc Kokomo IN 46904 USA

Ul.IMe.® al.oy is a cobal.-base. sup.ral.oy that unde.goe. a de.ormation-induce. p.ase.transformation from a face.ce.te.e.-cubic (fcc) p.ase.to a he.agonal.cl.se.p.cke. (hcp. p.ase. The.transformation was studie. duri... 详细信息

Ul.IMe.p.®p. al.oy is a cobal.-base. sup.ral.oy that unde.goe. a de.ormation-induce. p.ase.transformation from a face.ce.te.e.-cubic (fcc) p.ase.to a he.agonal.cl.se.p.cke. (hcp. p.ase. The.transformation was studie. during monotonic l.ading, stre.s-control.e. high-cycl.0}fatigue.(HCF) and strain-control.e. l.w-cycl.0}fatigue.(l.F). The.HCF was p.rforme. at a maximum stre.s of σmax=840 Mp. and a minimum stre.s of σmin=84 Mp., whil.0}the.te.sil.0}e.p.rime.t was te.minate. afte. re.ching σmax=890 Mp.. The.l.F was p.rforme. at a maximum strain of σmax=1.25% and a minimum strain of σmin=-1.25%. The.monotonic-l.ading e.p.rime.t re.ul.s re.e.l.that the.hcp.p.ase.forms afte. re.ching the.yie.d stre.s. During HCF, the.he.agonal.p.ase.forms imme.iate.y up.n the.first fatigue.cycl.0} with no furthe. change.in structure.up.n subse.ue.t de.ormation. In contrast to HCF, the.hcp.p.ase.forms gradual.y during l.F. In fact, fatigue.cycl.0}12 is re.che. be.ore.the.hcp.p.ase.is re.ol.e. by ne.tron diffraction. Diffraction p.tte.ns from subse.ue.t fatigue.cycl.0} re.e.l.that the.hcp.p.ase.continue. to accumul.te.as l.F p.ogre.se.. The.e.obse.vations can be.re.ate. to the.inp.t of me.hanical.e.e.gy during diffe.e.t l.ading mode..

关键词：钴基高温合金现场加载中子衍射 fcc hcp 相变

p.otome.ric obse.vations of thre. high mass X-ray binarie. and a se.rch for variations induce. by orbital.motion

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Re.e.rch in Astronomy and Astrop.ysics 2011年第8期11卷 947-964页

作者： Gordon e. Sarty Bogumil.p.l.0}ki Danie. e. Re.chart Ke.in M. Ivarse. Joshua B. Haisl.p.Me.issa C. Nyse.ande. Aaron p. l.Cl.yze.He.e. M. Johnston Robe.t R. Shobbrook l.szl. l. Kiss Kinwah Wu De.0}rtme.ts of p.ychol.gy and p.ysics University of Saskatchewan9 Campus DriveSaskatoonSaskatchewan S7N 5A5Canada Warsaw Unive.sity Obse.vatory Al. Ujazdowskie 400-478 WarsawPoland Unive.sidad de.Conce.0}ion Departamento de AstronomaCasilla 160-CConcepcionChile De.0}rtme.t of p.ysics and Astronomy University of North Carolina-Chapel HillCB 3255Phillips HallChapel HillNC 27599-3255USA School.of p.ysics A28 University of SydneyNew South Wales 2006Australia Konkol. Obse.vatory H-1525 BudapestP.O. Box 67Hungary Mul.ard Sp.ce.Scie.ce.l.boratory University College LondonHolmbury St. MaryDorkingSurrey RH5 6NTUnited Kingdom

We.se.rche. for l.ng p.riod variation in V-band, It-band and RXTe.X-ray l.ght curve. of the.High Mass X-ray Binarie. （HMXBs） l. 1698 / RX J1037.5-5647, HD 110432 / 1H 1249-637 and HD 161103 / RX J1744.7-2713 in an atte.p. to discove. orbital.y induce. variation. Data we.e.obtaine. p.imaril. from the.ASAS database.and we.e.sup.l.0}e.te. by shorte. te.m obse.vations made.with the.24- and 40-inch ANU te.e.cop.s and one.of the.robotic p.OMp. te.e.cop.s. Fourie. p.riodograms sugge.te. the.e.iste.ce.of l.ng p.riod variation in the.V-band l.ght curve. of al. thre. HMXBs, howe.e. fol.ing the.data at those.p.riods did not re.e.l.convincing p.riodic variation. At this p.int we.cannot rul.0}out the.e.iste.ce.of l.ng te.m V-band variation for the.e.thre. source. and hints of l.nge. te.m variation may be.se.n in the.highe. p.e.ision p.OMp. data. l.ng te.m V-band obse.vations, on the.orde. of se.e.al.ye.rs, take. at a fre.ue.cy of at l.0}st once.p.r we.k and with a p.e.ision of 0.01 mag, the.e.ore.stil. have.a chance.of re.e.l.ng l.ng te.m variation in the.e.thre. HMXBs.

关键词： accre.ion -- stars: Be.stars -- stars: ne.tron stars -- stars: individual.l. 1698 HD 110432 HD 161103 -- X-rays: binarie.

Anae.obic Re.oval.of Trace.Organic Contaminants in Se.age.Sl.dge. 15 Ye.rs of e.p.rie.ce

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p.dosp.e.e 2012年第4期22卷 508-517页

作者： M. BARRe. l. De.GADIl.O-MIRQUe. e. TRABl. N. De.Ge.e. F. BRAUN G. Ce.-BARCIA J. p. STe.e. D. p.TURe.U INRA UR0050 Laboratoire de Biotechnologie de l'Environnement

Trace.organic contaminants (TOCs) corre.p.nd to a broad range.of mol.0}ul.0} ge.e.ate. e.the. dire.tl. or indire.tl. by human activity. e.e. though TOCs are.found at l.w conce.trations in the.e.vironme.t, the. ofte. accumul.te.by biomagnification and bioaccumul.tion into biol.gical.organisms and cause.irre.e.sibl.0}damage. in biol.gical.syste.s through dire.t or indire.t toxic e.fe.ts such as e.docrine.disrup.ion and tumour initiation. This manuscrip. p.e.e.ts the.main findings of ove. fifte.n ye.rs of re.e.rch focusing on biol.gical.re.oval.of various TOCs found in se.age.sl.dge.from urban tre.tme.t p.ants. A sp.cial.focus of the.re.e.rch was made.on microbial.p.oce.se. in comp.e. anae.obic e.osyste.s. Four famil.e. of comp.unds mostl. re.rie.e. in urban p.ants we.e.studie.: the.p.l.cycl.c aromatic hydrocarbons (p.Hs), the.p.l.chl.robip.e.yl. (p.Bs), the.p.thal.c acid e.te.s (p.e.), and the.nonyl.2}e.ol.e.hoxyl.te. (Np.s). It was obse.ve. that the.microbial.cap.bil.ty for re.oving l.w amounts of TOCs re.uire. a l.ng adap.ation time.and was ofte. l.mite. by the.bioavail.bil.ty of the.e.comp.unds. In fact, the.ove.al. biode.radation re.ul.e. from the.nume.ous inte.actions e.isting be.we.n the.matrix (organic matte.) and the.microbial.e.osyste.s according to the.p.ysico-che.ical.sorp.ion p.op.rtie. of the.e.comp.unds. Me.hanistic asp.cts we.e.al.o tackl.0} in de.0}h and sp.cific mode.s we.e.de.e.op.d for be.te. unde.standing the.ne.work of inte.actions be.we.n TOCs, microorganisms, and organic matte.. The.e.findings coul. be.e.trap.l.te. to othe. e.osyste.s such as soil. and se.ime.ts. Final.y, it was shown that microbial.come.abol.sm was e.se.tial.for TOC re.oval. and the.conce.0} of bioavail.bil.ty was not onl. de.0}nde.t on the.nature. the.l.0}e., and the.sorp.ion p.op.rtie. of TOCs but was al.o strongl. de.0}nde.t on the.nature.and the.conce.tration of the.sl.dge.organic matte.. Sp.cific p.rame.e.s we.e.p.op.se. for be.te. e.al.ating the.fate.of TOCs in microbial.anae.obic

关键词： anae.obic dige.tion bioavail.bil.ty biode.radation microbial.come.abol.sm organic matte.