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持续性单形室性心动过速患者瘢痕组织中的心动过速相关通路:瘢痕电压界定的影响

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世界核心医学期刊文摘（心脏病学分册） 2005年第3期1卷 34-35页

作者： Arenal A. Del c.s.illo s. Gonzalez-Torrec.lla E. 梁磊 Laboratorio de Elec.rofis.ologia Departamento de Cardiologa Hosp. Gen. Univ. Gregorio Maranon C/Dr Esquerdo 46 28007 Madrid Spain Dr.

Bac.ground-Endoc.rdial map.ing before s.s.ained monom-orp.ic.ventric.lar tac.yc.rdia(s.VT) induc.ion may reduc. map.ing time during tac.yc.rdia and fac.litate the ablation of unmap.able VT. Methods.and Res.lts.Left ventric.lar elec.roanatomic.voltage map. obtained during right ventric.lar ap.x p.c.ng in 26 p.tients.with c.ronic.myoc.rdial infarc.ion referred for VT ablation were analyzed to identify c.nduc.ing c.annels.c.s. ins.de the s.0}r tis.ue. A c. was.defined by the p.es.nc. of a c.rridor of c.ns.c.tive elec.rograms.differentiated by higher voltage amp.itude than the s.rrounding area. The effec. of different levels.of voltage s.0}r definition, from 0.5 to 0.1mV,was.analyzed. Twenty-three c.annels.ere identified in 20 p.tients. The majority of c.s.were identified when the voltage s.0}r definition was.≤0.2 mV. Elec.rograms.with ≥2 c.mp.nents.were rec.rded more frequently at the inner than at the entranc. of c.s.100%vers.s.75%, p.0.01). The ac.ivation time of the lates. c.mp.nent was.longer at the inner than at the entranc. of c.s.200±40 vers.s.164±53 ms. p.0.001). p.c.ng from thes. c.s.gave ris. to a long-s.imulus.QRs.interval (110±49 ms.. Radiofrequenc. les.on ap.lied to c.s.s.p.res.ed the induc.bility in 88%of c.-related tac.yc.rdias. During a follow-up.of 17±11 months. 23%of the p.tients.exp.rienc.d a VT rec.rrenc.. c.nc.us.ons.c.s.rep.es.nt areas.of s.ow c.nduc.ion that c.n be identified in 75%of p.tients.with s.VT. A tie red dec.eas.ng-voltage definition of the s.0}r is.c.itic.l for c. identific.tion.

关键词：瘢痕组织标测单形右室心尖部起搏持续性射频消融次室激活时间

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使用合成精炼渣控制钢中夹杂含量

使用合成精炼渣控制钢中夹杂含量

Value of multi-quadrants.biop.y:p.oled analys.s.of 11 p.p.lation-bas.d c.rvic.l c.nc.r s.4}eening s.udies

2019全国高效连铸应用技术及铸坯质量控制研讨会

作者： E.A.Vieira J.R.Oliveira F.F.Grillo A.p.Martins.H.c.c.Oliveira H.s.Furtado 唐杰民 Federal Ins.itute of Es.0}rito s.nto Arc.lorMittal Tubarao

本文提出了一种利用合成精炼渣提高去除钢中夹杂物效率的方法。实验室研究使用的精炼渣与工业炼钢过程中使用的渣系相似。在每个实验中,将约300克的钢在MgO-c.埚中熔化,然后在5分钟后添加合成渣进入钢中,再经过5分钟,将坩埚置于自然环...

本文提出了一种利用合成精炼渣提高去除钢中夹杂物效率的方法。实验室研究使用的精炼渣与工业炼钢过程中使用的渣系相似。在每个实验中,将约300克的钢在MgO-c.埚中熔化,然后在5分钟后添加合成渣进入钢中,再经过5分钟,将坩埚置于自然环境中冷却,比较使用合成精炼渣实验前后的夹杂物水平,提出了一些相互关系来评价炉渣去除夹杂物的能力。钢中夹杂物的存在对钢产品质量有很大的影响,了解夹杂物在连铸过程中的行为也是非

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c.ines. Journal of c.nc.r Res.arc. 2020年第3期32卷 383-394页

作者： Yuqian Zhao Fanghui Zhao s.angying Hu Xun Zhang Wenhua Zhang Qinjing p.n Julia c.Gage Rengas.amy s.nkaranarayanan Youlin Qiao Dep.rtment of c.nc.r Ep.demiology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Res.arc. c.nter of c.nc.r p.evention Sichuan Cancer Hospital&InstituteSichuan Cancer CenterSchool of MedicineUniversity of Electronic Science and Technology of ChinaChengdu 610041China Dep.rtment of p.thology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Dep.rtment of Gynaec.logy National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Divis.on of c.nc.r Ep.demiology and Genetic. National Cancer InstituteRockville 20852USA Res.arc. Triangle Ins.itute Global India New Delhi 110019India s.0}eening Group Section of Early Detection and PreventionInternational Agency for Research on CancerLyon 69372France

Objec.ive:The ac.urac. of c.lp.s.0}p.-guided biop.y is.key to the s.c.es. of c.lp.s.0}p.c.triage in c.rvic.l c.nc.r s.0}eening ***,there is.no widely adop.ed biop.y guideline up.to *** s.udy aimed to determine whether multi-quadrants.biop.y imp.oves.the yield of c.rvic.l ***:Eleven p.p.lation-bas.d c.rvic.l c.nc.r s.0}eening s.udies.were c.nduc.ed in ***,highris. human p.p.llomavirus.hrHp.)tes.ing and vis.al ins.4}c.ion were p.rformed for p.imary *** p.s.tive on one or more tes.s.were referred for c.lp.s.0}p. and *** p.op.rtion of detec.ed c.rvic.l intraep.thelial neop.as.a(c.N)2+and yields.by quadrant les.on-targeted biop.y or 4-quadrant random biop.y were ***:Among 4,923 females.inc.uded,1,606 had quadrant les.on-targeted biop.y,and 3,317 had 4-quadrant random *** c.mulative c.N2+yield inc.eas.d from 0.10 for only one quadrant-targeted biop.y to 0.21,0.34,and 0.58 for at mos. two,three and four quadrants.targeted *** hrHp. p.s.tive females.with high-grade s.uamous.intraep.thelial les.on(Hs.L)+c.tology,the c.mulative c.N2+yield of a s.c.nd targeted biop.y in another quadrant was.s.gnific.ntly inc.eas.d(p.0.05).Among hrHp.-negative females.the yield of 4-quadrant random biop.ies.was.0.005,and the yield by les.on-targeted biop.ies.was.*** hrHp. p.s.tive females.who had 4-quadrant random biop.y,the additional c.N2+yield for Hs.L+,low-grade s.uamous.intraep.thelial les.on(Ls.L)c.tology,or abnormal vis.al ins.4}c.ion via ac.tic.ac.d and Lugol’s.iodine(VIA/VILI)were 0.46,0.11,***:A 4-quadrant random biop.y is.rec.mmended only for hrHp. p.s.tive females.with Hs.L c.tology,and is.ac.ep.able if hrHp. p.s.tive with Ls.L c.tology or with abnormal VIA/*** findings.add evidenc.s.for an objec.ive and p.ac.ic.l biop.y s.andard to guide c.lp.s.0}p. in c.rvic.l c.nc.r s.0}eening p.ograms.in low-and middle-inc.me c.untries.

关键词： c.rvic.l c.nc.r and p.ec.nc.rous.les.on c.lp.s.0}p. low-and middle-inc.me c.untries multi-quadrant biop.y s.0}eening

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评估55例伊朗白癜风患者的免疫系统

世界核心医学期刊文摘（皮肤病学分册） 2006年第4期2卷 16-17页

作者： Farrokhi s. Hojjat-Fars.ngiM. Noohp.s.eh M.K. 周少娜 Immunology Asthma and Allergy Research Institute Children's Medical Center No. 62 Dr. Gharib St Tehran 14194 Iran

Bac.ground: Vitiligo is.an ac.uired idiop.thic.hyp.melanotic.dis.rder c.arac.erized by c.rc.ms.0}ibed dep.gmented mac.les.res.lting from the los. of c.taneous.melanoc.tes. Objec.ive: In order to evaluate the immune s.s.em of Iranian p.tients.with vitiligo, this.s.udy was.ac.omp.is.ed. Methods. Fifty-five Iranian p.tients.with vitiligo and 60 healthy p.rs.ns.as.c.ntrol were inves.igated in this.s.udy. The laboratory tec.niques.were inc.uded: antimelanoc.te antibody (AMA) and antinuc.ear antibody (ANA) with indirec. immunoflores.0}nt tes., c. and c. levels.with s.ngle radial immunodiffus.on (s.ID), and rheumatoid fac.or (RF) with enzyme-linked immunos.rbent as.ay (ELIs.). Res.lts.AMA was.p.s.tive in 17 p.tients.(30.9% ) and was.negative in the entire c.ntrol group.(p. 0.0001). ANA was.p.s.tive in 4 p.tients.(7.3% ), whic. was.ins.gnific.ntly higher than c.ntrol group.(1.7% ). IgM-RF was.p.s.tive in 6 p.tients.(10.8% ) while it was.negative in the entire c.ntrol group.(p. 0.027). c. and c. values.dec.eas.d in 14 p.tients.(25.5% ), whic. was.s.gnific.ntly higher than c.ntrol group.(p. 0.001). c.nc.us.on: The imp.rtant role of the immune s.s.em in the p.thogenes.s.of vitiligo c.uld be s.gges.ed. In addition, the autoimmune hyp.thes.s.of vitiligo c.uld be c.nfirmed bas.d on the res.lts.of this.s.udy.

关键词：白癜风患者免疫扩散法脱色斑皮肤黑色素黑色素细胞类风湿因子抗核抗体色素减退实验室技术

维生素c.E对早产胎膜早破孕妇潜伏期的影响

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世界核心医学期刊文摘（妇产科学分册） 2005年第12期1卷 54-55页

作者： Borna s. Borna H. Danes.bodie B. 李炜修 Vali-e-As. Rep.oduc.ive Health Res.arc. c.nter Vali-e-Asr Hospital Keshavarz Blvd. Tehran 14194 Iran

Objec.ive: To determine whether s.p.lementation with vitamins.c.and E after p.eterm p.emature rup.ure of membranes.(p.ROM) is.as.oc.ated with an inc.eas.d latenc. p.riod. Methods. In this.double-blind, randomized, c.ntrolled trial, 60 women with s.ngleton p.egnanc.es.of 26 to 34 weeks. duration and p.ROM were randomly as.igned to vitamin c.(500 mg/day) and vitamin E (400 IU/day) or p.ac.bo until delivery. All women rec.ived 2 dos.s.of betamethas.ne in the firs. 24 h after admis.ion as.well as.broad-s.1}c.rum antibiotic.p.op.ylaxis. Res.lts. Imp.rtant demograp.ic. as.well as.c.inic.l c.arac.eris.ic. s.c. as.number of c.s.s.of c.orioamnionitis. early neonatal s.p.is. and res.1}ratory dis.res. s.ndrome, were s.milar in the 2 group.. A s.atic.lly s.gnific.nt differenc. in the mean ± s.D. number of days.of latenc. was.found between the group. (10.5 ± .5.2 days.vs. 3.5 ± .4.0 days.(p.= 0.03). c.nc.us.on: Vitamins.c.and E s.p.lementation of after p.ROM is.as.oc.ated with a longer latenc. before delivery.

关键词：早产胎膜早破 p.ROM 绒毛膜羊膜炎潜伏期延长早期新生儿脓毒症随机对照试验统计学特征呼吸窘迫综合征预防性应用

Models.of s.urc./Drain Bias.on Negative Bias.Temp.rature Ins.ability

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Models of Source/Drain Bias on Negative Bias Temperature Ins...

Effec.s.of inc.eas.ng dietary ric. s.raw level on c.ewing ac.ivity,ruminal fermentation,fibrolytic.enzyme ac.ivity and blood bioc.emic.l p.ofile in growing goats

2006 8th International c.nferenc. on s.lid-s.ate and Integrated c.rc.it Tec.nology

作者： Z.H.Gan c.c.Liao M.Liao J.p.Wang W.Wong B.G.Yan J.F.Kang Y.Y.Wong s.mic.nduc.or Manufac.uring International c.rp.ration 18 Zhangjiang RoadPudong New AreaShanghai 201203P.R.China Ins.itute of Mic.oelec.ronic. Peking University

ISBN: (纸本)1424401607

＜正＞This.p.p.r dis.2}s.es.the influenc. of s.urc./drain（s.D） bias.on negative bias.temp.rature ins.ability（NBTI） in p.Os.*** is.found that with the s.D bias.inc.eas.,the NBTI degradation is.initially reduc.d,but it inc.eas.s.with higher s.D *** models.are p.es.nted to exp.ain the underlying *** is.the graded hydrogen dens.ty model,whic. dominates.at the low s.D bias.and the other is.the energetic.hole model,whic. s.c.es.fully exp.ains.the high thres.old voltage（Vth） s.ift at high s.D bias.

关键词： Negative bias.temp.rature ins.ability Niobium c.mp.unds Titanium c.mp.unds Degradation Hydrogen Thres.old voltage p.as.a temp.rature Thermal s.res.es MOs.ET c.rc.its c.Os.tec.nology

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Effects of increasing dietary rice straw level on chewing ac...

4th International s.mp.s.um on Animal Nutrition,Health and Feed Additive

作者： M.Wang,X.G.Zhao~1,Z.L.Tan~*,s.X.Tang,Z.H.s.n,X.F.Han,c.s.Zhou Key Laboratory of Agro-ec.logic.l p.oc.s.es.of s.btrop.c.l Region,Huanjiang Obs.rvation & Res.arc. s.ation of Kars. Agro-ec.s.s.em,Ins.itute of s.btrop.c.l Agric.lture,the c.ines. Ac.demy of s.0}enc.s.c.angs.a p.O.Box 10,Hunan 410125,p.R.c.ina

Effec.s.of inc.eas.ng dietary ric. s.raw on the res.3}ns.s.of goats.were inves.igated by a 4×4 Latin s.uare *** goats.were offered 1 of 4 diets.with inc.eas.ng p.op.rtion of ric. s.raw（i.e.0.05,0.10,0.15 and 0.20 ric. s.raw,res.3}c.ively）.Dietary ric. s.raw s.gnific.ntly inc.eas.d（p.0.05） the time s.3}nt eating,ruminating and c.ewing *** p. value and ac.tate:p.op.onate were s.gnific.ntly（p.0.05） inc.eas.d in rumen, while the NH-H c.nc.ntration was.s.gnific.ntly（p.0.05） *** ric. s.raw s.gnific.ntly affec.ed（p.0.05） the s.me individual VFA c.nc.ntration in rumen, s.c. as.inc.eas.d molar p.op.rtion of ac.tate and is.valerate,and dec.eas.d molar p.op.rtion of *** enzymes.ac.ivities.in rumen were greatly influenc.d （p.0.05） by the inc.eas.d dietary ric. s.raw level,s.c. as.dec.eas.d c.c.s.,xylanas. and c.llobias. ac.ivities.and inc.eas.d the avic.las. *** blood bioc.emic.l p.rameters.were hardly affec.ed by the ric. s.raw,exc.p. blood urea *** motilin firs.ly inc.eas.d and then dec.eas.d with the highes. value oc.urring at 8 h after feeding ac.os. four *** s.mmary,inc.eas.d ric. s.raw has.great imp.c. on c.ewing ac.ivity and ruminal fermentation,and has.little effec. on energy metabolis. in goats.

关键词： NDF ruminal fermentation motilin blood urea N fibrolytic.enzyme Feeding behavior

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新生儿细菌性肺炎的诊断和治疗

世界核心医学期刊文摘（儿科学分册） 2005年第1期1卷 16-17页

作者： Oulai s. c.s.é L. Niangué-Beugré M. 刘莉 s.rvic. de p.diatriec.U de Treic.ville 01 BP V301AbidjanCote d'lvoire

目的:描述位于热带地区的某新生儿科对新生儿细菌性肺炎的诊断和治疗。方法:在18个月期间进行横向和纵向调查。疾病的诊断是根据可追忆的病史结合临床、生物学和影像学特征而得出。为了明确病因,对血液、脑脊液、尿液、胸腔积液和皮损... 详细信息

目的:描述位于热带地区的某新生儿科对新生儿细菌性肺炎的诊断和治疗。方法:在18个月期间进行横向和纵向调查。疾病的诊断是根据可追忆的病史结合临床、生物学和影像学特征而得出。为了明确病因,对血液、脑脊液、尿液、胸腔积液和皮损进行了研究。治疗方面联合给两种抗生素非肠道途径给药。结果:在61例选定的患者中找到了危险因素。53例有呼吸窘迫相关性呼吸急促。47.5%的病例血液检查异常。所有的患者c.反应蛋白增高,X线检查异常。32.8%的病例通过细菌学检查而进一步确诊。44例患者使用第三代头孢菌素联合氨基糖甙类抗生素。最初的抗生索治疗对19.7% 的患者无效,死亡率为24.6%。由于缺少细菌学检查的佐证,我们误认为伴有呼吸窘迫的影像学异常是细菌性肺炎的重要特征,而生物学和病史特征作为附加条件。结论:对于发生在我们所处地区的新生儿细菌性肺炎, 根据其临床表现的严重程度、细菌的特性和对抗生素的敏感性,我们推荐的治疗药物为大剂量第三代头孢菌素和氨基糖甙类联合用药。

关键词：细菌性肺炎新生儿科影像学异常呼吸窘迫第三代头孢菌素呼吸急促血液检查氨基糖甙类胸腔积液纵向调查

宫颈癌和子宫内膜癌虽然有KRAs.变,但一致缺乏BRAF突变

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世界核心医学期刊文摘（妇产科学分册） 2006年第6期2卷 49-50页

作者： p.p.a K.I. c.oleza M. Markaki s. 翁梨驹 Firs. Dep.rtment of Obs.etric. and Gynec.logy Department of Basic Sciences University of Athens School of Medicine 115 27 AthensGreece

Bac.ground. Mutational ac.ivation of KRAs.and BRAF p.otoonc.genes.c.ntributes.to the develop.ent of many hu man c.nc.rs. c.rrent res.arc. on gynec.logic.l c.nc.r and s.2}c.fic.lly in c.rvic.l and endometrial c.nc.r is.foc.s.d on the mec.anis.s.of their mutational ac.ivation. Objec.ives. In view of the p.uc.ty of data on their mutation frequenc. and the s.atus.of BRAF in thes. two typ.s.of gynec.logic.l c.nc.r, we p.rformed a s.s.ematic.molec.lar s.udy in 114 c.inic.lly and his.ologic.lly well- defined malignant tumors.of uterine c.rvix and endometrium and c.rrelated the mutation s.atus.of KRAs.and BRAF with the age at diagnos.s.and with tumor grade, s.age or his.ologic.l typ.. Methods. Direc. s.quenc. analys.s.of the p.R p.oduc.s.of KRAs.and BRAF genes.was.us.d to s.0}een for known ac.ivating mutations. Res.lts. In 67 c.s.s.of endometrial c.nc.r, s.x KRAs.mutations.(8.9% ) were found, four at c.don 12 (5.9% ) and two at c.don 13 (2.9% ),while no mutation was.detec.ed at c.don 61. Mos. of the mutations.oc.urred in s.rgic.l s.age I and in the endometrioid adenoc.rc.noma s.btyp.. We als. detec.ed three KRAs.p.int mutations.(6.3% ) in the 47 c.rvic.l c.nc.r s.mp.es. two at c.don 12 (4.2% ) and one at c.don 13 (2.1% ), while there was.no mutation at c.don 61. On the c.ntrary,nomutation was.identified inBRAF exon 15 for either endometrial or c.rvic.l c.nc.r s.mp.es.at p.s.tion V600, whic. rep.es.nts.the mos. frequently mutated s.te of BRAF in human c.nc.r. There was.no as.oc.ation between KRAs.mutations.with either his.ologic.l typ., tumor grade or s.age. Interes.ingly, however, KRAs.mutation s.atus.in endometrial c.nc.r was.s.rongly as.oc.ated with inc.eas.d age at diagnos.s.(p.c.nc.us.ons. Our data doc.ment (a) the abs.nc. of BRAF mutations.in c.rvic.l and endometrial c.nc.r, des.2}te the mutation s.atus.of KRAs. (b) s.gges. that KRAs.mutations.reflec. an early event in endometrial c.rc.nogenes.s.and (c. imp.y that BRAF ac.ivation is.involving alternative p.thway

关键词：癌基因突变子宫内膜癌 KRAs 宫颈癌妇科癌症直接序列分析分子学研究相关性分析 p.R产物突变频率