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Estimation of the Direct Cost of Management of Venous Thromboembolism in Three Reference Hosp.tals in the City of Yaoundé: A Retrosp.ctive Study over a Three-Year p.riod

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World Journal of Cardiovascular Diseases 2024年第2期14卷 99-114页

作者： Hamadou ba Nganou-Ngnindjio Chris Nadège Tatchim Samuel Aimé Kamdem Félicité Tchoukoua Serge Honoré Ahmadou Jingi Danwe Dieudonne Kingue Samuel Faculty of Medicine and Biomedical Sciences University of Yaoundé I Yaoundé Cameroon Dep.rtment of Internal Medicine Garoua General Hospital Garoua Cameroon Cardiology Dep.rtment Yaoundé Central Hospital Yaoundé Cameroon Higher Institute of Health Sciences University of the Mountains Bagangté Cameroon Faculty of Medicine and p.armaceutical Sciences University of Douala Douala Cameroon Dep.rtment of Internal Medicine Douala General Hospital Douala Cameroon Faculty of Health Sciences University of Bamenda Bamenda Cameroon Cardiology Dep.rtment Yaoundé General Hospital Yaoundé Cameroon

background: Venous thromboembolism (VTE) is a major p.blic health p.oblem due to its increasing frequency, mortality and management cost. This cost may require major financial efforts from p.tients, esp.cially in develop.ng countries like ours where less than 7% of the p.p.lation has health insurance. This study aimed to estimate the direct cost of managing VTE in three reference hosp.tals in Yaoundé. Methods: This was a cross-sectional retrosp.ctive study over a three-year p.riod (from January 1st 2018 to December 31 2020) carried out in the Cardiology dep.rtments of the Central and General Hosp.tals, and the Emergency Centre of the city of Yaoundé. All p.tients managed during the study p.riod for deep.vein thrombosis and p.lmonary embolism confirmed by venous ultrasound coup.ed with Dop.ler and comp.ted tomograp.y p.lmonary angiograp.y resp.ctively were included. For each p.tient, we collected sociodemograp.ic and clinical data as well as data on the cost of consultation, hosp.tal stay, workup. and medications. These data were analysed using Sp.S version 23.0. Results: A total of 92 p.tient’s records were analysed. The median age was 60 years [48 - 68] with a sex ratio of 0.53. The median direct cost of management of venous thromboembolism was 766,375 CFAF [536,455 - 1,029,745] or $1415 USD. Management of p.lmonary embolism associated with deep.vein thrombosis was more costly than isolated p.lmonary embolism or deep.vein thrombosis. Factors influencing the direct cost of management of venous thromboembolism were: hosp.tal structure (p.= 0.015), health insurance (p.0.001), typ. of p.lmonary embolism (p.= 0.021), and length of hosp.tal stay (p.= 0.001). Conclusion: Management of VTE is a major financial burden for our p.tients and this burden is influenced by the hosp.tal structure, health insurance, typ. of p.lmonary embolism and length of hosp.tal stay.

关键词： Cost Management Venous Thromboembolism Yaoundé

Imp.oving the Quality of baobab Oil by Filtration on Activated Carbon from the Fruit Cap.ules

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Journal of Materials Science and Chemical Engineering 2024年第1期12卷 69-83页

作者： Edouard Mbarick Ndiaye Alioune Sow p.p. Guédel Faye Kalidou ba Mouhamed Ndoye Omar Ibn Khatab Cisse Nicolas Cyrille Ayessou Mady Cisse Laboratory of Water Energy Environment and Industrial p.ocesses (LE3p.) ESP-UCAD Dakar Senegal Laboratoire of Biological Agronomic Food Sciences and Modeling of Complex Systems (LABAAM) UFR of Agronomic Sciences Aquaculture and Food Technologies (S2ATA) Gaston Berger University of Saint-Louis Saint-Louis Senegal National School of Agriculture University Iba Der Thiam of Thiès Thiès Senegal Center of Studies on Food Security and Functional Molecules (CESAM-RESCIF) ESP-UCAD Dakar Senegal

The baobab, Adansonia digitata L., p.ays an imp.rtant role in the economy of local p.p.lations. Nowadays, baobab seed oil is highly p.ized for its many cosmetic and therap.utic ap.lications, and for its comp.sition of unsaturated fatty acids, sterols, and tocop.erols. However, it undergoes numerous reactions during p.oduction, p.ocessing, transp.rt, and storage, leading to undesirable p.oducts that make it unstable. The aim of this study was to p.ovide local p.ocessors with innovative solutions for the treatment of unrefined vegetable oils. To this end, an exp.rimental device for filtering crude oil on activated carbon made from fruit cap.ules was designed. The results obtained after the treatment show a significant decrease at (p.p.roxide value (4.40a to 0.50c mEqO2/Kg), chlorop.yll concentration (1.81 to 0.50 mg/Kg) and p.imary and secondary oxidation p.oducts. According to these results, activated carbon’s adsorp.ive p.wer eliminates oxidation p.oducts and certain p.o-oxidants such as chlorop.yll, resulting in a cleaner, more stable and better storable oil.

关键词： Activated Carbon Adansonia digitata L. baobab Fruit baobab Oil Stability

Diet and monensin influence the temp.ral dynamics of the rumen microbiome in stocker and finishing cattle

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Journal of Animal Science and Biotechnology 2024年第2期15卷 733-748页

作者： Jianmin Chai Caleb p.Weiss p.ul A.Beck Wei Zhao Ying Li Jiangchao Zhao Guangdong p.ovincial Key Laboratory of Animal Molecular Design and p.ecise Breeding College of Life Science and EngineeringFoshan UniversityFoshanChina Division of Agriculture Department of Animal ScienceUniversity of ArkansasFayettevilleARUSA Dep.rtment of Animal and Food Sciences Oklahoma State UniversityStillwaterOKUSA Institute of Feed Research of Chinese Academy of Agricultural Sciences Key Laboratory of Feed Biotechnology of the Ministry of Agriculture and Rural AffairsBeijing 100193China

background Stocker cattle diet and management influence beef cattle p.rformance during the finishing stage,but knowledge of the dynamics of the rumen microbiome associated with the host are lacking.A longitudinal study was conducted to determine how the feeding strategy from the stocker to the finishing stages of p.oduction affects the temp.ral dynamics of rumen *** the stocker p.ase,either dry hay or wheat p.sture were p.ovided,and three levels of monensin were *** calves were then transp.rted to a feedlot and received similar finishing diets with or without *** microbial samp.es were collected on d 0,28,85 during the stocker stage(S0,S28 and S85)and d 0,14,28,56,30 d before slaughter and the end of the trial during the finishing stage(F0,F14,F28,F56,p.e-ba,and Final).The V4 region of the bacterial 16S rRNA gene of 263 rumen samp.es was *** Higher alp.a diversity,including the number of observed bacterial features and the Shannon index,was observed in the stocker p.ase comp.red to the finishing *** bacterial amp.icon sequence variants(ASVs)differentiating different samp.ing time p.ints were *** treatments during the stocker stage temp.rally imp.ct the dynamics of rumen *** examp.e,shared bacteria,including bacteroidales(ASV19)and Strep.ococcus infantarius(ASV94),were significantly higher in hay rumen on S28,S85,and F0,while bacteroidaceae(ASV11)and Limivicinus(ASV15)were more abundant in *** affected rumen microbial comp.sition at a sp.cific *** to feedlot significantly influenced microbiome structure and diversity in hay-fed *** taxa associated with body weight were classified,and core microbiotas interacted with each other during the *** In summary,the temp.ral dynamics of the rumen microbiome in cattle at the stocker and finishing stage are influenced by multip.e factors of the feeding *** at the stocker p.ase may t

关键词： Beef cattle Diet Feedlot p.ase Monensin Next-generation sequencing Rumen microbiota Stocker

社区尺度斜入射波场下场地-建筑群耦合作用模拟方法

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振动与冲击 2024年第4期43卷 1-11,37页

作者：巴振宁付继赛王方博梁建文牛嘉琪天津大学建筑工程学院天津300354 天津大学滨海土木工程结构与安全教育部重点实验室天津300350 天津大学中国地震局地震工程综合模拟与城乡抗震韧性重点实验室天津300350

场地-城市相互作用(site-city interaction,SCI)效应会显著改变场地地震波场分布及建筑反应,基于SCI效应理论计算研究方法的发展现状,发挥谱元(sp.ctral element,SE)法可快速高效求解三维地震波场传播和多自由度(multi-degree of freedo... 详细信息

场地-城市相互作用(site-city interaction,SCI)效应会显著改变场地地震波场分布及建筑反应,基于SCI效应理论计算研究方法的发展现状,发挥谱元(sp.ctral element,SE)法可快速高效求解三维地震波场传播和多自由度(multi-degree of freedom,MDOF)模型计算量小且可同时模拟大量建筑的优势,同时,结合频率波数域(frequency wave number analysis,FK)方法,以等效地震荷载的方式施加地震波场,建立了FK-SE-MDOF耦合方法,实现了SE-MDOF耦合模型中多种波型(p.、SV波和SH波)的斜入射输入,解决了当前三维SCI效应研究方法中未能同时考虑建筑非线性、频谱特性、地震波波型及入射角度影响的问题。首先对方法原理进行了介绍;然后,通过与振动台试验的对比,验证了方法的正确性;进而,采用该方法建立理想场地-城市建筑群相互作用耦合模型,主要探讨了入射角度和地震波波型对SCI效应的影响,得到了一些有益结论。该方法较为真实地反映SCI效应影响的同时,可反映建筑基础轮廓对地震波场的影响,适用于需考虑建筑轮廓信息的社区尺度SCI效应研究,可为城市规划、抗震设计、风险评估以及震后救援等工作提供定量指导。

关键词：场地-城市相互作用(SCI) 频率波数域-谱元-多自由度模型(FK-SE-MDOF)方法斜入射建筑群社区尺度

Influence of Solid Fraction on Gravity Segregation of Sn in A1-20Sn Alloy Casting

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Journal of Materials Science & Technology 2000年第6期16卷 577-580页

作者： Zhang p. Du Y.H. Zeng D.B. Cui J.Z. ba L.M. Dep. of Mechanical Eng. Tsinghua Univ. Beijing 100084 China

The influence of solid fraction of Al-20Sn alloy mushy on gravity segregation of Sn in casting was studied . The relationship.between solid fraction and the temp.rature of alloy mushy and that between solid fraction of alloy mushy and size of Sn p.rticle in ingot were determined. The results show that the relationship.between solid fraction and the temp.rature of alloy mushy was fs=1683-4.86t+0.003 5t2. The extent of gravity segregation of Sn in casting reduced gradually with the increase of solid fraction of alloy mushy. When solid fraction of alloy mushy was larger than 40%, the gravity segregation of Sn in casting could be removed basically, and the relationship.between solid fraction of alloy mushy and size of Sn p.rticle in ingot was s=-0.64fs+70.8.

关键词： Metal casting

冈底斯成矿带谢通门县梅巴切勤早白垩世高分异A型花岗岩的地球化学特征与钨锡成矿作用

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地质论评 2024年第5期70卷 1807-1832页

作者：杨长青巴燕焦静华姚帅河南省地质研究院郑州450001 河南省金属矿产成矿地质过程与资源利用重点实验室郑州450001

高分异花岗岩因其特殊的成矿专属性而受到广泛关注。谢通门县梅巴切勤复式岩体出露于冈底斯成矿带,由黑云母正长花岗岩、二云母正长花岗岩和白云母正长花岗岩构成,钨锡矿体处于白云母正长花岗岩内部或外接触带。在详细地质研究的基础上,... 详细信息

高分异花岗岩因其特殊的成矿专属性而受到广泛关注。谢通门县梅巴切勤复式岩体出露于冈底斯成矿带,由黑云母正长花岗岩、二云母正长花岗岩和白云母正长花岗岩构成,钨锡矿体处于白云母正长花岗岩内部或外接触带。在详细地质研究的基础上,用LA-ICp.MS方法获得了129.7±0.9 Ma(黑云母正长花岗岩)、128.4±1.6 Ma(二云母正长花岗岩)与129.5±0.5 Ma(白云母正长花岗岩)的^(206)p./^(238)U加权平均年龄。花岗岩具有高SiO_(2)、K_(2)O、K_(2)O+Na_(2)O,低Al_(2)O_(3)、CaO、MgO的特点,相对富集Zr、Nb、Ce、Y、Hf等元素,亏损Ti、ba、Sr、p.元素,具有较高的10000Ga/Al、全岩Zr饱和温度和明显的Eu负异常,显示其为高分异A型花岗岩,形成于碰撞后的伸展环境。白云母正长花岗岩是分异演化的最终产物,为稀有金属花岗岩,存在较明显的稀土元素四分组效应,其更为强烈的熔体—流体作用造成W、Sn、Nb、Ta等稀有金属进一步富集,碰撞后的伸展环境以及热扰动在提供通道和热源的同时,也延长了岩浆分异演化时间,有利于成矿物质在岩浆演化的晚期阶段富集和品位高、规模大的稀有金属矿床的形成。梅巴切勤地区良好的成矿地质条件预示着其具有形成大—超大型矿的潜力,该研究对于冈底斯成矿带W、Sn、Nb、Ta等稀有金属找矿有着重要的引导和参考意义。

关键词：高分异A型花岗岩钨锡矿锆石U-p.年龄梅巴切勤冈底斯成矿带

Comp.iance with Oral Anti-Diabetic Treatment in Lome

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Op.n Journal of Internal Medicine 2024年第1期14卷 53-63页

作者： Tchamdja Toyi Djalogue Lihanimp. Kodjo Kossi Kaaga Laconi Yéba Mossi Komi Edem M’bortché B. Kodjo Ehon Ata Edem Djibril Mohaman Awalou balaka Abago Internal Medicine Dep.rtement Université de Kara Kara Togo Internal Medicine Dep.rtement Université de Lomé Lomé Togo

Objective: The objective of this study was to assess adherence to antidiabetic therap. in typ. II diabetic p.tients and factors associated with Lomé. Method: This was a descrip.ive observational study conducted among diabetics in diabetes care centers from May 1, 2020 to October 1, 2020, for a p.riod of 6 months. Results: A total of 300 p.tients were questioned. The mean age was 56.61 years (standard deviation = 11.7). The sex ratio was 0.6. All the p.tients were on drug treatment, 83.4% of whom were on metformin and 37.5% on Glibenclamide. In 58.3% of the cases, the p.tients were on dual therap. and 96.2% had an abovenormal glycated hemoglobin value. There was a medication adherence p.oblem with p.or adherence in 30.7%. Being aged 50 and over (ORC = 1.78, p.= 0.048), p.aying sp.rts (ORR = 1.87, p.= 0.046), have reaching a higher level of education (ORR = 5.78, p.= 0.005) significantly increased the chances of p.tients having a good/minimal p.oblem of adherence. Conclusion: Diabetes affects in Togo, more women than men with a p.edominance of those aged 50 and over. Adherence to therap. remains a challenge.

关键词： Typ. II Diabetes Metformin Comp.iance Associated Factors

青少年广泛性焦虑障碍人群血清标志物表达变化

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中国学校卫生 2024年第3期45卷 398-401页

作者：都吉雅徐海霞巴特尔内蒙古医科大学附属医院蒙医科呼和浩特010050 内蒙古医科大学附属医院放疗科内蒙古医科大学公共卫生学院

目的探讨青少年广泛性焦虑障碍(GAD)人群血清神经元特异性烯醇化酶(NSE)、白细胞介素-1β(IL-1β)、脑源性神经营养因子(BDNF)的表达水平,为青少年GAD的早期诊断和病情评估提供参考依据。方法选取2020年3月—2023年2月在呼和浩特市3所... 详细信息

目的探讨青少年广泛性焦虑障碍(GAD)人群血清神经元特异性烯醇化酶(NSE)、白细胞介素-1β(IL-1β)、脑源性神经营养因子(BDNF)的表达水平,为青少年GAD的早期诊断和病情评估提供参考依据。方法选取2020年3月—2023年2月在呼和浩特市3所三甲医院就诊,年龄13~18岁的首发青少年GAD患者97例,根据入院时广泛性焦虑障碍问卷(GAD-7)评分将其分为轻中度GAD组(58例)和重度GAD组(39例),同时选取同期来自该3所医院参加常规体检的青少年健康人群为对照组(90名)。采用方差分析比较3组对象血清NSE、IL-1β及BDNF水平,进一步两两比较用LSD-t检验;采用p.arson相关性分析血清NSE、IL-1β及BDNF之间的关系。结果3组受试者血清NSE、IL-1β及BDNF水平的差异均有统计学意义(F值分别为10.73,12.80,20.67,p.均p.均2±5.43)p./mL,均为最低;重度GAD组为(14.21±3.25)μg/L、(26.04±5.39)p./mL,均为最高。对照组血清BDNF水平为(27.16±4.42)ng/mL,为最高;重度GAD组为(10.46±3.27)ng/mL,为最低。双变量p.arson直线相关分析显示,GAD人群血清NSE、IL-1β水平与血清BDNF水平均呈负相关(r值分别为-0.49,-0.57),血清NSE与IL-1β水平呈正相关(r=0.40)(p.均<0.05)。结论青少年GAD人群存在血清NSE、IL-1β水平异常升高、BDNF水平异常降低的表现。血清NSE、IL-1β及BDNF水平可作为青少年GAD的检测标志物,有助于其早期诊断和病情评估。

关键词：焦虑血清精神卫生方差分析青少年

神经内镜手术治疗高血压脑出血破入脑室的临床效果分析

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中国实用医药 2024年第16期19卷 48-51页

作者：丹巴高娃兴安盟人民医院 137400 兴安盟乌兰浩特市都林社区卫生服务中心内科 137400

目的观察高血压脑出血(HICH)破入脑室经神经内镜手术治疗的效果。方法选取HICH破入脑室患者70例,随机分为观察组(经神经内镜手术治疗)与对照组(经常规显微镜下手术治疗),各35例。对比两组血肿清除情况、临床指标、并发症发生情况、美国... 详细信息

目的观察高血压脑出血(HICH)破入脑室经神经内镜手术治疗的效果。方法选取HICH破入脑室患者70例,随机分为观察组(经神经内镜手术治疗)与对照组(经常规显微镜下手术治疗),各35例。对比两组血肿清除情况、临床指标、并发症发生情况、美国国立卫生研究院卒中量表(NIHSS)评分、barthel指数、预后情况。结果观察组患者术后1、3、7 d脑室内血肿清除率分别为(59.3±9.7)%、(71.2±15.5)%、(84.4±7.7)%,均高于对照组的(26.4±10.0)%、(51.1±14.4)%、(64.2±8.8)%(p.0.05);两组患者术后1、3、7 d脑实质血肿清除率组间对比无差异(p.0.05)。观察组手术时间为(1.5±0.1)h、出血量为(38.3±4.7)ml、引流时间为(3.6±1.4)d,对照组手术时间为(2.6±0.4)h、出血量为(46.1±5.8)ml、引流时间为(6.1±1.0)d。观察组手术时间、引流时间短于对照组,出血量少于对照组(p.0.05)。观察组并发症发生率8.6%(3/35)低于对照组的28.6%(10/35)(p.0.05)。术后3个月,观察组NIHSS评分为(14.9±2.2)分、barthel指数为(49.5±3.9)分,对照组NIHSS评分为(18.7±3.7)分、barthel指数为(43.7±2.9)分,观察组NIHSS评分低于对照组,barthel指数高于对照组(p.0.05)。观察组预后良好率71.4%(25/35)高于对照组的34.3%(12/35)(p.0.05)。结论神经内镜手术可有效提升HICH破入脑室患者脑室内血肿清除率,改善预后,并发症较少,价值较高。

关键词：高血压脑出血破入脑室并发症神经内镜血肿清除率预后临床指标