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Flow of newtonian Fluid in non-Uniform Tubes with Application to Renal Flow:A numerical Study

Advances in Applied Mathematics and Mechanics 2011年第5期3卷 633-648页

作者： p.Muthu Tesfahun Berhane Department of Mathematics National Institute of TechnologyWarangalWarangal 506004India

In this paper,a numerical method employing a finite difference technique is used for an investigation of viscous,incompressible fluid flow in a tube with absorbing wall and slowly varying *** effect of fluid absorption through permeable wall is accounted by prescribing flux as a function of axial *** method is not restricted by the parameters in the problem such as wave number,permeability parameter,amplitude ratio and Reynolds *** effects of these parameters on the radial velocity and mean pressure drop is studied and the results are presented *** is also made between the results obtained by perturbation method of solution and present approach.

关键词： non-uniform tube renal flow Takabatake finite difference scheme.

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Effects of intrapulmonary percussive ventilation on airway mucus clearance: A bench model

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World Journal of Critical Care Medicine 2017年第3期6卷 164-171页

作者： Lorena Fernandez-Restrepo Lauren Shaffer Bravein Amalakuhan Marcos I Restrepo Jay peters Ruben Restrepo Division of pediatric Critical Care Division of Pulmonary and Critical Care and Department of Respiratory Care University of Texas Health Science Center and the South Texas Veterans Health Care System

AIM To determine the ability of intrapulmonary percussive ventilation(IpV) to promote airway clearance in spontaneously breathing patients and those on mechanical *** An artificial lung was used to simulate a spontaneously breathing patient(Group 1), and was then connected to a mechanical ventilator to simulate a patient on mechanical ventilation(Group 2). An 8.5 mm endotracheal tube(ETT) connected to the test lung, simulated the patient airway. Artificial mucus was instilled into the mid-portion of the ETT. A filter was attached at both ends of the ETT to collect the mucus displaced proximally(mouth-piece filter) and distally(lung filter). The IpV machine was attached to the proximal end of the ETT and was applied for 10-min each to Group 1 and 2. After each experiment, the weight of the various circuit components were determined and compared to their dry weights to calculate the weight of the displaced *** In Group 1(spontaneously breathing model), 26.8% ± 3.1% of the simulated mucus was displaced proximally, compared to 0% in Group 2(the mechanically ventilated model) with a p-value of n fact, 17% ± 1.5% of the mucus in Group 2 remained in the mid-portion of the ETT where it was initially instilled and 80% ± 4.2% was displaced distally back towards the lung(p n overall statistically significant amount of mucusmovement proximally towards the mouth-piece in the spontaneously breathing(SB) patient. There was also an overall statistically significant amount of mucus movement distally back towards the lung in the mechanically ventilated(MV) model. In the mechanically ventilated model, no mucus was observed to move towards the proximal/mouth piece section of the ETT. COnCLUSIOn This bench model suggests that IpV is associated with displacement of mucus towards the proximal mouthpiece in the SB patient, and distally in the MV model.

关键词： Mucus Sputum Mechanical ventilators percussion Respiratory drainage Breathing exercises

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Multisensor Information Fusion for Condition Based Environment Monitoring

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Intelligent Automation & Soft Computing 2023年第4期36卷 1013-1025页

作者： A.Reyana p.Vijayalakshmi Department of Computer Science and Engineering Hindusthan College of Engineering and TechnologyCoimbatore641050India Department of Electronics and Communication Engineering Hindusthan College of Engineering and TechnologyCoimbatore641050India

Destructive wildﬁres are becoming an annual event,similar to climate change,resulting in catastrophes that wreak havoc on both humans and the *** result,however,is disastrous,causing irreversible damage to the *** location of the incident and the hotspot can sometimes have an impact on earlyﬁre detection *** the advancement of intelligent sen-sor-based control technologies,the multi-sensor data fusion technique integrates data from multiple sensor *** primary objective to avoid wildﬁre is to identify the exact location of wildﬁre occurrence,allowingﬁre units to respond as soon as *** to predict the occurrence ofﬁre in forests,a fast and effective intelligent control system is *** proposed algorithm with decision tree classiﬁcation determines whetherﬁre detection parameters are in the acceptable range and further utilizes a fuzzy-based optimization to optimize the complex *** experimental results of the proposed model have a detection rate of ***,providing real-time monitoring of certain environ-mental variables for continuous situational awareness and instant responsiveness.

关键词： Decision tree communication wildﬁre data fusion wireless sensor networks

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Melatonin modifies SOX2^+ cell proliferation in dentate gyrus and modulates SIRT1 and MECp2 in long-term sleep deprivation

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neural Regeneration Research 2019年第10期14卷 1787-1795页

作者： Alan Hinojosa-Godínez Luis F. Jave-Suarez Mario Flores-Soto Alma Y. Gálvez-Contreras Sonia Luquín Edith Oregon-Romero Oscar González-pérez Rocio E. González-Castaneda Laboratorio de Microscopía de Alta Resolución Departamento de NeurocienciasCentro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajaraMéxico Laboratorio de neurociencias Facultad de PsicologíaUniversidad de ColimaColimaMéxico División de Inmunología Centro de Investigación Biomédica de OccidenteInstituto Mexicano del Seguro SocialGuadalajaraMéxico División de neurociencias Centro de Investigación Biomédica de OccidenteInstituto Mexicano del Seguro SocialGuadalajaraMéxico Instituto de Investigación en Ciencias Biomédicas (IICB) Departamento de Biología Molecular y GenómicaCentro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajaraMéxico Unidad de Atención en neurociencias Departamento de Neurociencias. Centro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajaraMéxico

Melatonin is a pleiotropic molecule that,after a short-term sleep deprivation,promotes the proliferation of neural stem cells in the adult ***,this effect has not been observed in long-term sleep *** precise mechanism exerted by melatonin on the modulation of neural stem cells is not entirely elucidated,but evidence indicates that epigenetic regulators may be involved in this *** this study,we investigated the effect of melatonin treatment during a 96-hour sleep deprivation and analyzed the expression of epigenetic modulators predicted by computational text mining and keyword *** results showed that the administration of melatonin under sleep-deprived conditions increased the MECp2 expression and reduced the SIRT1 expression in the dentate *** observed that let-7 b,mir-132,and mir-124 were highly expressed in the dentate gyrus after melatonin administration,but they were not modified by sleep *** addition,we found more Sox2^+/5-bromo-2’-deoxyuridine(BrdU)^+cells in the subgranular zone of the sleep-deprived group treated with melatonin than in the untreated *** findings may support the notion that melatonin modifies the expression of epigenetic mediators that,in turn,regulate the proliferation of neural progenitor cells in the adult dentate gyrus under long-term sleep-deprived *** procedures performed in this study were approved by the Animal Ethics Committee of the University of Guadalajara,Mexico(approval ***-16610)on January 2,2016.

关键词： sleep-deprivation melatonin microRnA neurogenesis Sirtuin 1 SIRT1 methyl-CpG-binding protein 2 MECp2 epigenetic text-mining mir-9 let-7b

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腹股沟疝复发的时间分析

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中国实用外科杂志 2011年第4期31卷 336-340页

作者： Magnusson n nordin p Hedberg M Gunnarsson U Sandblom G Department of Surgery Mora HospitalMoraSweden Department of Surgery stersund HospitalstersundSweden CLInTEC Division of SurgeryKarolinska InstitutetStockholmSweden

目的假设不同术式疝修补术术后复发的发病过程是不同的,那么疝复发的时间也是不同的。该研究的目的是分析影响初次手术到复发后再次手术时间间隔的危险因素。方法研究数据来自瑞典疝登记注册系统。将5年随访期间的每一年的资料作为亚组... 详细信息

目的假设不同术式疝修补术术后复发的发病过程是不同的,那么疝复发的时间也是不同的。该研究的目的是分析影响初次手术到复发后再次手术时间间隔的危险因素。方法研究数据来自瑞典疝登记注册系统。将5年随访期间的每一年的资料作为亚组分列,后合为大组。对于每个危险因素以再次手术为研究终点,运用Cox回归分析复发时间与危险因素之间的关系。结果共分析了142578例,其中7.7%是女性,年龄平均59岁。5年总体复发率为4.3%。多因素分析显示复发疝修补后再次复发的时间较早(pppp<0.05)。结论不同术式疝修补术后复发的发病过程是不同的。腹腔镜修补、传统疝修补术(不应用补片)和复发疝修补术后早期复发率高可能是由于手术技术失误率较高。

关键词：疝复发注册登记术后并发症网片

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