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瓣膜性和非瓣膜性房颤患者中抗血小板药物、抗凝药物或二者联合应用的随机多中心研究

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世界核心医学期刊文摘（心脏病学分册） 2005年第3期1卷 51-52页

作者： pérez-gómez f. Alegra E. Berjón J 杜媛

This trial evaluated the ef.icacy and saf.ty of.the combination of.antiplatelet and moderate-intensity anticoagulation therapy in patients with atrial f.brillation associated with recognized risk f.ctors or mitral stenosis. Warf.rin was more ef.ective than aspirin in preventing stroke in these patients; combined therapy with low anticoagulant intensity was inef.ective. Mitral stenosis patients were not investigated. We perf.rmed a multicenter randomized trial in 1,209 patients at risk. The intermediate-risk group included patients with risk f.ctors or age >60 years: 242 received the cyclooxygenase inhibitor trif.usal, 237 received acenocumarol, and 235 received a combination of.both. The high-risk group included patients with prior embolism or mitral stenosis: 259 received anticoagulants and 236 received the combined therapy. Median f.llow-up was 2.76 years. primary outcome was a composite of.vascular death and nonf.tal stroke or systemic embolism. primary outcome was lower in the combined therapy than in the anticoagulant arm in both the intermediate-(hazard ratio0.33 [95%conf.dence interval(CI)0.12 to 0.91]; p=0.02) and the high-risk group(HR 0.51[95%CI 0.27 to 0.96]; p=0.03). primary outcome plus severe bleeding was lower with combined therapy in the intermediate-risk group. Nonvalvular and mitral stenosis patients had similar embolic event rates during anticoagulant therapy. The combined antiplatelet plus moderate-intensity anticoagulation therapy signif.cantly decreased the vascular events compared with anticoagulation alone and proved to be saf. in atrial f.brillation patients.

关键词：非瓣膜性房颤抗凝药物膜性二尖瓣狭窄栓塞事件非致死性脑卒中抗凝剂醋硝香豆素随机试验合并治疗

BaTiO3 solid solutions co-doped with gd3+ and Eu3+:Synthesis,structural evolution and dielectric properties

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Journal of.Rare Earths 2024年第10期42卷 1920-1926页

作者： R.Martínez-López M.pérez-Labra J.A.Romero-Serrano f.R.Barrientos-Hernández M.Reyes-pérez M.I.Valenzuela-Carrillo g.Urbano-Reyes V.E.Reyes-Cruz g.I.Dávila-pulido Academic Area of.Earth Sciences and Materials Autonomous University of Hidalgo State Metallurgy and Materials Department ESIQIE-IPNUPALM Autonomous University of.Coahuila Boulevard Adolfo López Mateos S/n

In this paper,the synthesis,structural evolution,and dielectric properties of.BaTiO3solid solutions codoped with rare earth elements(gd3+and Eu3+) prepared using the solid-state reaction method are *** pure precursor powders of.BaCl3,TiO2,gd2O3,and Eu2O3were mixed in stoichiometric proportions,ground in an agate mortar bef.re being uniaxially pressed at 250 Mpa and sintered at 1300℃ in air atmosphere f.r 6 h to obtain Ba1-3xgd2xTi1-3xEu4xO3（x=0,0.0015,0.01 and0.1）.X-ray dif.raction（XRD） and Rietveld's ref.nement results reveal the crystal phase f.rroelectric tetragonal BaTiO3f.r the samples with x=0,0.0015 and 0.01, as well as a consistent increment in the lattice parameters caused by the *** solubility limit of.gd3+and Eu3+in the BaTiO3structure is reached f.r the sample with x>0.01,and the orthorhombic Eu2TiO5and monoclinic BaTi2O5secondary phases were *** Raman results show the characteristic peaks of.f.rroelectric tetragonal BaTiO3around 716 cm-1（LO of.A1 symmetry）,515 cm-1（TO of.A1 symmetry）,and 305 cm-1（B1）.The maximum relative permittivity measured at 1 kHz was recorded to be 6151.8 f.r the sample with x=0.0015,and a decrease in the Curie temperature to 105℃ with respect to the undoped sample was *** punctual microanalysis f.r the samples with x=0.0015,0.01,and 0.1 reveals grains composed of.Ba,Ti,O,gd,and Eu homogeneously distributed in the *** Ba/Ti ratios f.r samples with x=0.0015,0.01 and 0.1 are 2.86,2.91,and 0.68,respectively,indicating substitution at the Ti site f.r samples with x=0.0015 and 0.01 and a substitution at the Ba site f.r the sample with x=0.1.

关键词： BaTiO3 Doping Europium gadolinium Rare earths Synthesis

Exact solutions f.r magnetohydrodynamic nanof.uids f.ow and heat transf.r over a permeable axisymmetric radially stretching/shrinking sheet

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Chinese physics B 2024年第2期33卷 108-114页

作者： U.S.Mahabaleshwar g.p.Vanitha L.M.pérez Emad H.Aly I.pop Department of.Studies in Mathematics Davangere UniversityShivagangothriDavangereIndia Departamento de f.ısica FACIUniversidad de Tarapac´aCasilla 7DAricaChile Department of.Mathematics Faculty of EducationAin Shams UniversityRoxyCairoEgypt Department of.Mathematics Babes-Bolyai University400084 Cluj-NapocaRomania

We report on the magnetohydrodynamic impact on the axisymmetric f.ow of.Al_(2)O_(3)/Cu nanoparticles suspended in H_(2)O past a stretched/shrinked *** the use of.partial dif.erential equations and the corresponding thermophysical characteristics of.nanoparticles,the physical f.ow process is *** resultant nonlinear system of.partial dif.erential equations is converted into a system of.ordinary dif.erential equations using the suitable similarity *** transf.rmed dif.erential equations are solved *** of.the magnetic parameter,solid volume f.action and stretching/shrinking parameter on momentum and temperature distribution have been analyzed and interpreted *** skin f.iction and Nusselt number were also *** addition,existence of.dual solution was deduced f.r the shrinking sheet and unique solution f.r the stretching ***,Al_(2)O_(3)/H_(2)O nanof.uid f.ow has better thermal conductivity on comparing with Cu/H_(2)O ***,it was f.und that the f.rst solutions of.the stream are stable and physically realizable,whereas those of.the second ones are unstable.

关键词： magnetohydrodynamic nanof.uid stretching/shrinking sheet axisymmetric f.ow analytical solution suction/injection

Research f.resight in bridging open science and open innovation:Overview based on the complex thinking paradigm

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International Journal of.Innovation Studies 2024年第1期8卷 59-75页

作者： Jorge Sanabria-Z Marco Cruz-Sandoval Athziri Moreno-Romo Sof.a Bosch-gómez María Soledad Ramírez-Montoya Institute f.r the f.ture of.Education Tecnologico de MonterreyZapopan45201Mexico Central Bohemian Innovation Center(SIC) PragueCzech Republic The Burnes Center f.r Social Change Northeastern UniversityBostonMA02115USA Institute f.r the f.ture of.Education Tecnologico de MonterreyMonterrey64700Mexico

Open innovation benef.ts f.om access to cutting-edge discoveries to increase their transf.rmation into tangible applications f.r the benef.t of.*** research quality has been proposed as a primary objective of.open science by the United Nations,to increase science reproducibility,impact,and trust,leading to robust decision-making and ***,opening access to data and processes is insuf.icient f.r researchers to achieve open innovation in the context of.globalization,f.r example,by gathering insights f.om external and internal *** the appropriate mindset to manage complexity and generate synergy among researchers in academia,industry,and the government is essential to catalyze knowledge and transf.rm it into relevant innovations f.r *** gain insights into the roles and challenges of.researchers aiming to bridge the gap between open science and open innovation,a decade-plus Mapping Literature Review was conducted based on the complex thinking *** thinking allows f.r novel connections of.the inf.rmation collected through open science and open innovation,considering dif.erent f.rms of.engaging with alternative means of.knowledge creation that may promote innovative and critical *** f.ndings revealed:a)broad positioning of.the terms in the European Union;b)open access and open data as current driving themes;c)a constant trade-of. between the terms“open data”and“inf.rmation protection”;d)lack of.studies on researchers’complex thinking to help them manage openness;e)absence of.the environmental helix in the initiatives;and(f.challenges in innovative communication and collaborative practices among public and private ***,we identif.ed an opportunity to develop researchers’complex thinking such that the openness of.inf.rmation becomes a shared responsibility among partners across multiple *** shared responsibility can have methodological implications that permeate how open science and ope

关键词： Open innovation Open science Complex thinking Ecosystems Research enhancement Educational innovation Higher education

High CO_(2)permeation using a new Ce_(0.85)gd_(0.15)O_(2-δ)-LaNiO_(3)composite ceramic–carbonate dual-phase membrane

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Journal of.Environmental Sciences 2024年第6期140卷 219-229页

作者： Daniela gonzález-Varela Jf.ancisco gómez-garcía gustavo Tavizon Heriberto pf.if.er Instituto de Investigaciones en Materiales Universidad Nacional Autónoma de MéxicoCd.UniversitariaDel.CoyoacánCP 04510Ciudad de MéxicoMéxico Departamento de f.sica y Química Teórica Facultad de QuímicaUniversidad Nacional Autónoma de MéxicoCd.UniversitariaDel.CoyoacánCP 04510Ciudad de MéxicoMéxico 不详

This work shows the synthesis,characterization and evaluation of.dense-ceramic membranes made of.Ce_(0.85)gd_(0.15)O_(2-δ)-LaNiO_(3)(Cg-LN)composites,where the f.uorite-perovskite ratio(Cg:LN)was varied as f.llows:75:25,80:20 and 85:15 wt.%.Supports were initially characterized by XRD,SEM and electrical conductivity(using vacuum and oxygen atmospheres),to determine the composition,microstructural and ionic-electronic conductivity ***,supports were inf.ltrated with an eutectic carbonates mixture,producing the corresponding dense dual-phase membranes,in which CO_(2)permeation tests were ***,CO_(2)permeation experiments were perf.rmed f.om 900 to 700℃,in the presence and absence of.oxygen(f.owed in the sweep membrane side).Results showed that these composites possess high CO_(2)permeation properties,where the O_(2)addition signif.cantly improves the ionic conduction on the sweep membrane ***,the gC80-LN20 composition presented the best results due to the f.llowing physicochemical characteristics:high electronic and ionic conductivity,appropriate porosity,interconnected porous channels,as well as thermal and chemical stabilities between the composite support and carbonate phases.

关键词： CO_(2)permeation Doped CeO_(2) LaNiO_(3) Impedance Ceramic carbonate membrane

Adsorption of.pharmaceutical pollutants on ZnCl_(2)-activated biochar f.om corn cob:Ef.iciency,selectivity and mechanism

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Journal of.Bioresources and Bioproducts 2024年第1期9卷 58-73页

作者： Christian f.Varela L.C.Moreno-Aldana Yazmin Yaneth Agámez-pertuz Department of.Chemistry National University of ColombiaAv.Carrera 30 No.45-03BogotáD.C.Colombia Department of.Biology and Chemistry University of the Llanoskm 12 road to Puerto LópezVillavicencioColombia

The occurrence of.pharmaceuticals in water bodies and drinking water poses risks f.r the envi-ronment and human health,thus it is necessary to study methodologies that allow the ef.icient removal of.these *** this work,corn cob-derived biochar was obtained by ZnCl_(2)-activation,and subsequent carbonization at 700℃.The ef.ect of.contact time,temperature,pH,and initial concentration on the adsorption capacity of.acetaminophen(ACE)and amoxicillin(AMX)was determined through batch *** addition,the kinetics,isotherms,and ther-modynamics parameters were *** activated biochar exhibited a maximum adsorp-tion capacity of.332.08 mg/g f.r ACE and 175.86 mg/g f.r *** adsorption kinetics and adsorption isotherm of.ACE corresponded to the pseudo-second order and Langmuir model,***,pseudo-f.rst-order kinetics and the f.eundlich isotherm model were well-f.tted to AMX *** ACE and AMX co-adsorption had a synergistic ef.ect on AMX but an antagonistic ef.ect on ACE removal,achieving a maximum adsorption capacity of.193.51 and 184.58 mg/g,*** the other hand,f.xed-bed column experiments showed that the adsorption capacity depends on the inf.uent concentration,and the breakthrough curve f.ts the Thomas and Yoon-Nelson *** mechanism adsorption studies showed that surf.ce inter-actions(hydrogen bonding f.rmation and n-𝜋interactions)are the main driving f.rces f.r the adsorption process,and pore f.lling is the rate-limiting *** this way,the prepared biochar exhibits a high potential f.r the adsorption of.pharmaceutical compounds f.om water.

关键词： Biochar Adsorption Acetaminophen Amoxicillin Wastewater treatment

Robust hybrid bismuth perovskites as potential photocatalysts f.r overall water splitting

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Nano Research 2024年第5期17卷 4593-4601页

作者： Antonio J.Chacón-garcía Herme g.Baldovi Artem A.Babaryk Antonio Rodríguez-Diéguez Sergio Navalón Yolanda pérez Hermenegildo garcía patricia Horcajada Advanced porous Materials Unit IMDEA Energy InstituteAvda.Ramón y Cajal 328935 MóstolesMadridSpain Departamento de Química Universitat Politècnica de València46022 ValènciaSpain Departamento Química Inorgánica Universidad de Granada1807GranadaSpain Departamento de Biología y geología Física y Química Inorgánica.ESCET.Universidad Rey Juan Carlos28933 MóstolesMadridSpain Instituto de tecnología química CSIC-UpV Universitat Politècnica de València(UPV)46022Spain

Organic-inorganic hybrid perovskites have gained great attention as promising photocatalysts f.r hydrogen ***,due to their poor stability in water,the use of.aqueous hydrohalic acid solutions is specif.cally required f.r an ef.icient hydrogen ***,three novel photoactive lead-f.ee hybrid perovskites based on bismuth and triazolium cations(denoted as IEf.15,IEf.16,and IEf.17(IEf.stands f.r IMDEA energy f.ameworks))were synthesized and f.lly characterized(structural,compositional,optical,etc.).f.rther,these solids were proposed as photocatalysts f.r the challenging gas phase overall water splitting(OWS)***,IEf.16 thin f.lms exhibited a remarkable photocatalytic activity in both H_(2) and O_(2) evolution,as a consequence of.its appropriate bandgap and energy-band alignment,achieving hydrogen evolution rates of.mol·g_(H_(2))^(-)1846 and 360 af.er 24 h under ultraviolet-visible(UV-vis)irradiation or simulated solar irradiation,*** study additionally highlights the remarkable structural and photochemical stability of.IEf.16 under dif.erent operational conditions(*** volume,irradiation and temperature),paving the way f.r green hydrogen production f.om OWS using perovskite-based photocatalysts.

关键词： bismuth-based hybrid perovskites thin f.lms photocatalysis overall water splitting green hydrogen

Stress tensors and quantif.cation of.f.acture patterns to analyze connectivity and potential f.uid f.ow in a mesa landf.rm of.the Northern Andes

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Journal of.Mountain Science 2024年第1期21卷 271-291页

作者： gARCÍA-ARIAS Sergio VELANDIA f.ancisco ALVArez Angélica SANABRIA-gÓmez JoséD TARAZONA Yessenia VARgAS María Camila Escuela de geología Universidad Industrial de SantanderCra.27 Calle 9BucaramangaColombia Escuela de f.sica Universidad Industrial de SantanderCra.27 Calle 9BucaramangaColombia

This work applies stress tensors inversions and quantif.cation of.f.acture patterns along the Mesa de Los Santos, in the Eastern Cordillera of.Colombia, to better understand the potential f.uid f.ow. It thus contributes to the conceptual hydrogeological model. The area was subdivided into three blocks, separated by the NW potreros and the Los Santos f.ults, having minor inner f.ults of.dif.erent orientations. This separation f.cilitates the analysis of.the f.actures measured in the f.eld, which in general show high dip angles and a conjugate geometry in the northern block, tension f.actures(Mode I) in the central block, and a random distribution in the southwestern block. WinTensor treatment of.slickensides yielded a maximum horizontal stress(SHmax) of.111o, which coincides with the WNW-ESE tensor observed f.om the conjugate and tension joints. We then used f.ac pa Q to generate interpolation maps of.f.acture intensity and density. The maps show the highest values in the central block and the lowest in the northern block,where the precipitation is higher, causing intensive rock weathering and homogenization of.the f.acture planes. Although the highest values of.connectivity by line are f.und to the south of.the mesa, we suggest the possibility of.greater f.ow f.om the recharge zone(NE) along bedding planes and open NW-SE f.actures.

关键词： Mesa de Los Santos Colombia Win-Tensor f.acpaQ Strike-slip f.ults f.actured aquif.rs

f.derated Network Intelligence Orchestration f.r Scalable and Automated f.-Based Anomaly Detection in B5g Networks

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Computers, Materials & Continua 2024年第7期80卷 163-193页

作者： pablo f.rnández Saura José M.Bernabé Murcia Emilio garcía de la Calera Molina Alejandro Molina Zarca Jorge Bernal Bernabé Antonio f.Skarmeta gómez Department of.Inf.rmation and Communications Engineering University of MurciaMurcia30100Spain University Center of.Def.nse Spanish Air Force AcademySan Javier30720Spain

The management of.network intelligence in Beyond 5g(B5g)networks encompasses the complex challenges of.scalability,dynamicity,interoperability,privacy,and *** are essential steps towards achieving the realization of.truly ubiquitous Artif.cial Intelligence(AI)-based analytics,empowering seamless integration across the entire Continuum(Edge,f.g,Core,Cloud).This paper introduces a f.derated Network Intelligence Orchestration approach aimed at scalable and automated f.derated Learning(f.)-based anomaly detection in *** leveraging a horizontal f.derated learning approach based on the f.dAvg aggregation algorithm,which employs a deep autoencoder model trained on non-anomalous traf.ic samples to recognize normal behavior,the systemorchestrates network intelligence to detect and prevent *** into a B5g Zero-touch Service Management(ZSM)aligned Security f.amework,the proposal utilizes multi-domain and multi-tenant orchestration to automate and scale the deployment of.f.-agents and AI-based anomaly detectors,enhancing reaction capabilities against *** proposed f. architecture can be dynamically deployed across the B5g Continuum,utilizing a hierarchy of.Network Intelligence orchestrators f.r real-time anomaly and security threat *** includes f. enf.rcement operations f.r interoperability and extensibility,enabling dynamic deployment,conf.guration,and reconf.guration on *** validation of.the proposed solution was conducted through dynamic orchestration,f.,and real-time anomaly detection processes using a practical test *** of.key perf.rmance metrics,leveraging the 5g-NIDD dataset,demonstrates the system’s capability f.r automatic and near real-time handling of.anomalies and attacks,including real-time network monitoring and countermeasure implementation f.r mitigation.

关键词： f.derated learning 6g orchestration anomaly detection security policy