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Non-part.cipat.on of asympt.mat.c candidat.s in screening prot.cols reduces early diagnosis and worsens prognosis of colorect.l cancer

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World Journal of Gast.oent.rology 2024年第26期30卷 3198-3200页

作者： Sergio pérez-Holanda Office of Regional Viceminist.y of Healt. Regional Viceministry of HealthOviedo 33005AsturiasSpain

t.e Agat.uma et.al’s st.dy shows t.at.despit. t.e evidence of t.e benefit. of an early colorect.l cancer(CRC)diagnosis,t.rough screening in asympt.mat.c subject.,up t. 50%of candidat.s reject.t.is opt.on and many of t.ose affect.d are diagnosed lat.r,in advanced *** efficacy of screening programs has been well-est.blished for several years,which reduces t.e risk of CRC morbidit. and mort.lit.,wit.out.t.king int. account.t.e t.st.used for screening,or ot.er ***,a significant.proport.on of pat.ent. remain unscreened,so underst.nding t.e fact.rs involved,as well as t.e barriers of t.e populat.on t. adherence is t.e first.st.p t. possibly modify t.e part.cipat.on *** barriers could include a full range of social and polit.cal aspect.,especially t.e t.pe of financial provision of each healt. *** Japan,healt. services are universal,and t.is advant.geous sit.at.on makes it.easier for cit.zens t. access t. t.ese services,cont.ibut.ng t. t.e det.ct.on of various diseases,including ***,t.e sympt.mat.c CRC group had a lower early-st.ge diagnosis rat. t.an t.e pat.ent. det.ct.d during follow-up for ot.er comorbidit.es,and sympt.mat.c and cancer screening groups showed similar early-st.ge diagnosis.

关键词： Colorect.l neoplasms Cancer regist.y Diagnost.c rout. Cancer screening St.ge at.diagnosis

Calibrat.on of t.e DEM sliding frict.on and rolling frict.on paramet.rs of a cohesionless bulk mat.rial

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part.cuology 2024年第9期92卷 126-139页

作者： Jonat.n Marín pérez t.grul Comlekci Yevgen Gorash Donald MacKenzie Universit. of St.at.clyde 75 Montrose StreetG11XJGlasgowUnited Kingdom

t.e discret. element.met.od(DEM)has become a valuable t.ol for underst.nding t.e mechanical behaviour of granular assemblies,however,t.e accuracy of t.e DEM simulat.ons depends on several int.ract.on paramet.rs such as t.e sliding frict.on and rolling frict.on ***,t.ese paramet.rs are est.mat.d using bulk calibrat.on approach(BCA)where t.e draw down t.st.has been suggest.d as an effect.ve way t. approach t.ese *** t.st.provides up t. four bulk crit.ria,t.e angle of repose,shear angle,mass flow rat. and t.e mass loss which are used t. narrow down t.e possible ***,t.ere is st.ll more research needed around it.t. fully underst.nd how t.is met.odology *** experiment.l and numerical st.dy was carried out.using t.e draw down t.st.t. assess t.e influence of different.mass flow rat.s and part.cle shapes on DEM paramet.rs for a cohesionless bulk *** is concluded t.at.use of mult.-sphere part.cles and t.ree apert.re sizes in t.e draw down t.st.t. calibrat. t.e sliding and rolling frict.on paramet.rs of a cohesionless bulk mat.rial can converge t. a small feasible region in which a single combinat.on of t.e frict.on coefficient. can be *** calibrat.d sliding and rolling frict.on coefficient. were validat.d using mult.-sphere part.cles,where t.e maximum deviat.on was 5.9%from t.e experiment.l values.

关键词： Discret. element.met.od Calibrat.on Draw down Sliding frict.on Rolling frict.on part.cle shape

Chromomagnet.c dipole moment. of light.quarks in t.e best.st.lit.le Higgs model

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Chinese physics C 2024年第10期48卷 125-136页

作者： t.Cisneros-pérez E.Cruz-Albaro A.Y.Ojeda-Cast.ñeda S.E.Solís-Núñez Unidad Académica de Ciencias Químicas Universidad Autónoma de ZacatecasApartado Postal C-58598060 ZacatecasMexico Facult.d de Física Universidad Autónoma de ZacatecasApartado Postal C-58098060 ZacatecasMexico

In t.is st.dy,we invest.gat.d t.e anomalous Chromomagnet.c Dipole Moment.CMDM),denot.d as μ_(q)^(BLHM),of light.quarks q=(u,c,d,s,b) wit.in t.e framework of t.e Best.st.Lit.le Higgs Model(BLHM)as an ext.nsion of t.e St.ndard Model(SM).Our invest.gat.on encompassed novel int.ract.ons among t.e light.quarks,heavy quark B,and heavy bosons (W'^(±),H^(±),φ^(±),η^(±))incorporat.ng t.e ext.nded Cabibbo-Kobayashi-Maskawa(CKM)mat.ix charact.rist.c of t.e *** t.oroughly explored t.e permissible paramet.r space,yielding a spect.um of CMDM values ranging from 10^(-10) t. 10^(-3).

关键词： beyond st.ndard model flavor physics chromomagnet.c dipole light.quarks

primary repair of esophageal at.esia Gross t.pe C via t.oracoscopic magnet.c compression anast.mosis:Is it.t.e best.opt.on?

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World Journal of Gast.oint.st.nal Surgery 2024年第5期16卷 1474-1481页

作者： Sonia pérez-Bert.lez Jorge Godoy-Lenz Depart.ent.of pediat.ic Surgery Sant Joan de Deu HospitalUniversity of BarcelonaBarcelona 08950Spain Depart.ent.of pediat.ic Surgery Clínica Alemana of SantiagoSantiago 7650568Chile

Magnet.c compression anast.mosis is a promising t.eat.ent.opt.on for pat.ent. wit. complex esophageal at.esia;but.at.t.e present.t.me,should not.be t.e first.t.erapeut.c opt.on in t.ose cases where t.e surgeon can per... 详细信息

关键词： Esophageal at.esia t.acheoesophageal fist.la t.oracoscopy Magnamosis Magnet.c anast.mosis

prot.in glycat.on:a wolf in sweet.sheep’s clot.ing behind neurodegenerat.on

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Neural Regenerat.on Research 2024年第5期19卷 975-976页

作者： Ana B.Uceda Francisco Leal-pérez Miquel Adrover Inst.t.t.Universit.ri d’Invest.gacióen Ciències de la Salut.IUNICS) Inst.t.t.d’Invest.gacióSanit.ria Illes Balears(IdISBa) Depart.ment.de Química Universitat de les Illes BalearsCtraPalma de MallorcaSpain

At.t.e beginning of t.e 16t. cent.ry,paracelsus coined t.e maxim:“t.e dose makes t.e poison”.t.is principle can be applied t. all living organisms,including organs and *** brain and it. glial and neuronal cells are ... 详细信息

关键词： organs sheep sweet

Exact.solut.ons for magnet.hydrodynamic nanofluids flow and heat.t.ansfer over a permeable axisymmet.ic radially st.et.hing/shrinking sheet

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Chinese physics B 2024年第2期33卷 108-114页

作者： U.S.Mahabaleshwar G.p.Vanit.a L.M.pérez Emad H.Aly I.pop Depart.ent.of St.dies in Mat.emat.cs Davangere UniversityShivagangothriDavangereIndia Depart.ment. de F´ısica FACIUniversidad de Tarapac´aCasilla 7DAricaChile Depart.ent.of Mat.emat.cs Faculty of EducationAin Shams UniversityRoxyCairoEgypt Depart.ent.of Mat.emat.cs Babes-Bolyai University400084 Cluj-NapocaRomania

We report.on t.e magnet.hydrodynamic impact.on t.e axisymmet.ic flow of Al_(2)O_(3)/Cu nanopart.cles suspended in H_(2)O past.a st.et.hed/shrinked *** t.e use of part.al different.al equat.ons and t.e corresponding t.ermophysical charact.rist.cs of nanopart.cles,t.e physical flow process is *** result.nt.nonlinear syst.m of part.al different.al equat.ons is convert.d int. a syst.m of ordinary different.al equat.ons using t.e suit.ble similarit. *** t.ansformed different.al equat.ons are solved *** of t.e magnet.c paramet.r,solid volume fract.on and st.et.hing/shrinking paramet.r on moment.m and t.mperat.re dist.ibut.on have been analyzed and int.rpret.d *** skin frict.on and Nusselt.number were also *** addit.on,exist.nce of dual solut.on was deduced for t.e shrinking sheet.and unique solut.on for t.e st.et.hing ***,Al_(2)O_(3)/H_(2)O nanofluid flow has bet.er t.ermal conduct.vit. on comparing wit. Cu/H_(2)O ***,it.was found t.at.t.e first.solut.ons of t.e st.eam are st.ble and physically realizable,whereas t.ose of t.e second ones are unst.ble.

关键词： magnet.hydrodynamic nanofluid st.et.hing/shrinking sheet axisymmet.ic flow analyt.cal solut.on suct.on/inject.on

Does enhanced recovery aft.r surgery programs improve clinical out.omes in liver cancer surgery?

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World Journal of Gast.oint.st.nal Oncology 2024年第2期16卷 255-258页

作者： Belinda Sánchez-pérez JoséM Ramia Depart.ent.of General Digestive and Transplantation SurgeryUniversity Regional HospitalMálaga 29010MálagaSpain Depart.ent.of Surgery Hospital General Universitario Dr.BalmisAlicante 03010Spain

Enhanced recovery aft.r surgery(ERAS)programs have been widely applied in liver surgery since t.e publicat.on of t.e first.ERAS guidelines in 2016 and t.e new recommendat.ons in *** surgery is usually performed in oncological pat.ent.(liver met.st.sis,hepat.cellular carcinoma,cholangiocarcinoma,et..),but.t.e real impact.of liver surgery ERAS programs in oncological out.omes is not.clearly *** advant.ges of ERAS programs are:ERAS decreases post.perat.ve complicat.on rat.s and has been demonst.at.d a clear relat.onship bet.een complicat.ons and oncological out.omes;a bet.er and fast.r post.-perat.ve recovery should let.oncologic t.ams begin chemot.erapeut.c regimens on t.me;prehabilit.t.on and nut.it.on act.ons before surgery should also improve t.e performance st.t.s of t.e pat.ent. receiving ***,ERAS could be anot.er way t. improve our oncological *** will discuss t.e lit.rat.re about.liver surgery ERAS focusing on it. oncological implicat.ons and fut.re invest.gat.ons project..

关键词： Enhanced recovery aft.r surgery programs Liver surgery Key component. Long-t.rm oncological out.omes Enhanced recovery aft.r surgery compliance

Novel umami pept.des from t.o t.rmit.myces mushrooms and molecular docking t. t.e t.st. recept.r t.R1/t.R3

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Food Science and Human Wellness 2024年第2期13卷 1055-1064页

作者： Lanyun Zhang Li Zhang Jesus pérez-Moreno Lu Bin Fengming Zhang Fuqiang Yu t.e Germplasm Bank of Wild Species Yunnan Key Laboratory for Fungal Diversity and Green DevelopmentKunming Institute of BotanyChinese Academy of SciencesKunming 650201China College of Chemical Science and t.chnology Yunnan UniversityKunming 650091China College of Food Science and t.chnology Yunnan Agricultural UniversityKunming 650201China Colegio post.raduados Campus MontecilloEdafologíaTexcoco 56230México Key Laborat.ry for Forest.Resources Conservat.on and Use in t.e Sout.west.Mount.ins of China Southwest Forestry UniversityKunming 650224China

Wild edible t.rmit.myces mushrooms are popular in Sout.west.China and umami is import.nt.flavor qualit.es of edible *** st.dy aimed t. underst.nd t.e umami t.st. of t.rmit.myces int.rmedius and t.rmit.myces *** umami pept.des from aqueous ext.act. were separat.d using a Sephadex G-15 gel filt.at.on *** int.nse umami fract.on was evaluat.d by bot. sensory evaluat.on and elect.onic *** were ident.fied as KLNDAQApK,DSt.EKFLR,VGKGAHLSGEH,MLKKKKLA,SLGFGGppGY,t.At.SSSt.pDD,AMDDDEADLLLLAM,VEDEDEKpKEK,SpEEKKEEEt.and *** pept.des,except.VEDEDEKpKEK,SpEEKKEEEt.and pEGADKpNK were select.vely synt.esized t. verify t.eir t.st. *** t.ese 10 pept.des had umami or salt.*** 10 pept.des were conduct.d by molecular docking t. st.dy t.eir int.ract.on wit. ident.fied pept.des and t.e umami t.st. recept.r t.R1/*** t.ese 10 pept.des perfect.y docked t.e act.ve residues in t.e t.R3 *** result. provide t.eoret.cal basis for t.e umami t.st. and address t.e umami mechanism of t.o wild edible t.rmit.myces mushrooms.

关键词： t.rmit.myces Non-volat.le flavor compounds Umami pept.des t.st. charact.rist.cs Molecular docking

Kent.sh plover(Charadrius alexandrinus) and Lit.le t.rn(St.rnula albifrons) prefer shells for nest.ng:A field experiment

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Avian Research 2024年第1期15卷 55-59页

作者： Macarena Cast.o Andrés De la Cruz Nuria Mart.n-Sanjuan Alejandro pérez-Hurt.do Inst.t.t. Universit.rio de Invest.gacion Marina(INMAR) Campus de Excelencia Internacional del Mar(CEIMAR)Departamento de BiologíaUniversidad de CadizPuerto RealSpain Servicios cent.ales de Invest.gacion Salinas de la Esperanza Universidad de CadizPuerto RealSpain

Shorebird populat.ons are declining worldwide,mainly due t. human dist.rbances and loss of coast.l ***,suprat.dal habit.t. as salt.ans could play a role in buffering human *** have shown t. be import.nt.as feeding or breeding sit.s of some shorebird species.A pot.nt.al conservat.on st.at.gy t. increase shorebird populat.ons in salt.ans is t. manipulat. t.e cues t.at.birds use t. select.opt.mal breeding *** it.is hypot.esized t.at.shorebirds are at.ract.d t. bivalve shells due t. t.e advant.ges t.ey *** t.is hypot.esis,we supplement.d a rest.red salt.an in 2019 and 2021 wit. bivalve shells,expect.ng an increase in t.e number of breeding birds’ *** t.an 75% of Kent.sh plover(Charadrius alexandrinus) and Lit.le t.rn(St.rnula albifrons) nest. were found in pat.hes wit. shells in bot. *** best.model for bot. species indicat.s t.at.t.e presence of shells is t.e fact.r t.at.most.correlat.s wit. t.e locat.on of *** probabilit. of choosing one place over anot.er t. set.le t.eir nest.increases in areas wit. an abundance of shells,double in t.e case of t.e Kent.sh plover and t.iple in t.e case of t.e Lit.le *** result.of t.is st.dy may const.t.t. a valuable t.ol for at.ract.ng birds t. rest.red salt.ans and could cont.ibut. t. t.e success of expensive rest.rat.on project. where t.me is usually a const.aint.

关键词： Habit.t.management Nest.sit. select.on Salt.an rest.rat.on Shell supplement.t.on Shorebirds