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Ionized calcium level predicts in-hospital mortality of severe sepsis patients:A retrospective cross-sectional study

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Journal of Acute Disease 2021年第6期10卷 247-251页

作者： Bora Cekmen Ramazan koylu Nazire Belgin Akilli Yahya Kemal Gunaydin oznur koylu Seref Emre Atis Basar Cander Department of Emergency Medicine Konya Education and Research HospitalKonyaTurkey Department of Emergency Medicine Ankara Education and Research HospitalAnkaraTurkey Department of Biochemistry Konya Education and Research HospitalKonyaTurkey Department of Emergency Medicine Mersin City HospitalMersinTurkey Department of Emergency Medicine Kanuni Sultan Suleyman Education and Research HospitalIstanbulTurkey

Objective:To evaluate the effect of serum ionized calcium levels on the prognosis of severe sepsis ***:This retrospective cross-sectional study included sepsis patients who were hospitalized in an intensive care unit between January 2011 and December *** demographic and baseline data of the patients who died and survived were *** cutoff value of ionized calcium for in-hospital mortality was determined by the receiver operating characteristics curve(ROC).In-hospital mortalities and the survival rates were compared between patients with different ionized calcium ***,the risk factor of in-hospital mortality was ***:This study included 145 patients with 113 patients who died in the *** patients who died had significantly lower ionized calcium levels(U=2.25,P=0.034).A cut-off value of 0.93 mmol/L of ionized calcium was determined by the ROC *** patients with ionized calcium>0.93 mmol/L showed a significantly lower morality(χ2=9.90,P=0.002)and higher survival rate than with≤0.93 mmol/L(log rank=6.20,P=0.010).Multivariate Cox regression revealed that ionized calcium≤0.93 mmol/L was a risk factor of in-hospital ***:Ionized calcium level≤0.93 mmol/L was an independent predictor of in-hospital mortality of severe sepsis.

关键词： Ionized calcium Critically illness Sepsis Mortality In-hospital

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