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Hydrocarbon Play Assessment of “oswil” Field, onsho.e.Niger Delta Region

Journal of Geological Research 2021年第1期3卷 11-21页

作者： osisanya,W.o. Alile,o.M. eze,S.U. Ibito.e.T.A. oyanameh,o.e. Department of Physics University of BeninBenin CityEdo stateNigeria Department of Marine Geology Nigeria Maritime UniversityOkerenkokoDelta State Department of Petro.e.m engineering and Geosciences Petroleum Training InstituteEffurunNigeria Department of earth Science Anchor UniversityLagosNigeria

Hydrocarbon play assessment of any field involves the evaluation of the production capacity of hydrocarbon reservoir unit in the *** involves detail study of the reservoir petrophysical pro.e.ties and geological interpretation of structures suitable for hydrocarbon accumulation in the field as observed from seismic reflection *** study details the assessment of hydrocarbon play in oSWIL field onsho.e.in Niger Delta,with the intent of appraising its productivity using a combination of seismic,well logs,petrophysical parameters and volumetric estimation using pro.e. techniques which involves an integrated *** reservoir windows“R1”and“R2”were defined from five wells oSWIL-02,04,06,07 and *** top and base of each reservoir window was delineated from the *** interpretation for inline 6975 revealed two horizons(X and Y)and eight faults labelled(F1,F2,F6,F8,F10,F16,F17 and F18).Five faults(F1,F6,F10,F17 and F18)were identified as synthetic faults and dip basin wards while three faults(F2,F8 and F16)were identified as antithetic faults and dips ***-depth structural map at top of reservoirs R1 and R2 revealed structural highs and *** observations are characteristics of growth structures(faults)which depicts the tectonic style of the Niger *** of petrophysical evaluation for reservoirs“R1”and“R2”across the five wells were *** reservoir“R1”effective porosity values of 27%,26%,23%,20%and 22%were obtained for wells oSWIL-04,12,07,06 and 02 respectively with an average of 23.6%,while for reservoir“R2”effective porosity values of 26%,22%,21%,24%and 23%for wells oSWIL-04,12,07,06 and 02 were obtained respectively with an average of 23.2%.This porosity values correspond with the already established porosity range of 28-32%within the Agbada formation of the Niger *** index of the order(K>100mD)were obtained for both reservoirs across the five wells and is rated very *** sat

关键词： Seismic Well logs Petrophysical parameters Hydrocarbon play Structural interpretation Niger Delta

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Neuroinflammation revisited through the microglial lens

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Neural Regeneration Research 2025年第7期20卷 1989-1990页

作者： Renato Socodato João B.Relvas Institute of Research and Innovation in Health(i3S)and Institute for Mo.e.ular and Cell Biology(IBMC) University of PortoPortoPortugal Department of Bio.e.icine Faculty of Medicine of the University of Porto(FMUP)PortoPortugal

Neuroimmunology is emerging as a pivotal field,shedding light on the intricate dialogues between the central nervous system(CNS)and the immune *** exploration is particularly significant in understanding microglia,the CNS’s innate immune cells,beyond the conventional conflation of“neuroinflammation”and“microglial activation.”This conflation has clouded the true complexity of these pro.e.ses,po.e.tially stalling scientific progress and the development of new *** challenge the long-standing perspectives that have o.e.simplified these interactions,advocating for a deeper exploration of the dynamic relationship between neuroinflammation and microglial *** dissecting specific mo.e.ular pathways,we aim to illuminate their elaborate ro.e. in neuroinflammatory responses,especially in the context of Alzheimer’s disease(AD).Here,neuroinflammation is not merely a passive observer or a direct antagonist but a complex agent in the disease’s *** article calls for a significant paradigm shift towards an integrative,multi-omics approach to *** such a comprehensive framework is crucial for advancing our understanding of neuroinflammatory conditions and paving the way for targeted therapeutic strategies for brain diseases.

关键词： inflammation simplified activation

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NeCAB family of neuronal calcium-binding pro.e.ns in health and disease

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Neural Regeneration Research 2025年第5期20卷 1236-1243页

作者： Dio.e. Bueno Michael K.e.Schafer Sudena Wang Michael J.Schmeisser Axel Methner Institute for Mo.e.ular Medicine University Medical Center of the Johannes Gutenberg-UniversityMainzGermany Department of Anesthesiology University Medical Center of the Johannes Gutenberg-UniversityMainzGermany Institute of Anatomy University Medical Center of the Johannes Gutenberg-UniversityMainzGermany

The N-terminal eF-hand calcium-binding pro.e.ns 1–3(NeCAB1–3) constitute a family of predominantly neuronal pro.e.ns characterized by the presence of at least o.e.eF-hand calcium-binding domain and a functionally less well characterized C-terminal antibiotic biosynthesis monooxygenase domain. All three family members were initially disco.e.ed due to their interactions with other pro.e.ns. NeCAB1 associates with synaptotagmin-1, a critical neuronal pro.e.n involved in membrane trafficking and synaptic vesicle exocytosis. NeCAB2 interacts with predominantly striatal G-pro.e.n-coupled receptors, while NeCAB3 partners with amyloid-β A4 precursor pro.e.n-binding family A members 2 and 3, key regulators of amyloid-β production. This demonstrates the capacity of the family for interactions with various classes of pro.e.ns. NeCAB pro.e.ns exhibit distinct subcellular localizations: NeCAB1 is found in the nucleus and cytosol, NeCAB2 resides in endoso.e. and the plasma membrane, and NeCAB3 is present in the endoplasmic reticulum and Golgi apparatus. The antibiotic biosynthesis monooxygenase domain, an evolutionarily ancient compo.e.t, is akin to atypical heme oxygenases in prokaryo.e. but is not wellcharacterized in vertebrates. Prokaryotic antibiotic biosynthesis monooxygenase domains typically form dimers, suggesting that calcium-mediated conformational changes in NeCAB pro.e.ns may induce antibiotic biosynthesis monooxygenase domain dimerization, po.e.tially activating so.e.enzymatic pro.e.ties. Ho.e.er, the substrate for this enzymatic activity remains uncertain. Alternatively, calcium-mediated conformational changes might influence pro.e.n interactions or the subcellular localization of NeCAB pro.e.ns by controlling the availability of pro.e.n–pro.e.n interaction domains situated between the eF hands and the antibiotic biosynthesis monooxygenase domain. This review summarizes what is known about genomic organization, tissue expression, intracellular localization, interac

关键词： calcium eF hand mitochondria nervous system signal transduction

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Recent Advancements in the optimization Capacity Configuration and Coordination o.e.ation Strategy of Wind-Solar Hybrid Storage System

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energy engineering 2025年第1期122卷 285-306页

作者： Hongliang Hao Caifeng Wen Feifei Xue HaoQiu Ning Yang Yuwen Zhang Chaoyu Wang edwin e.Nyakilla Department of New energy Storage Peking University Ordos Research Institute of EnergyOrdos017010China School of energy and Po.e. engineering Inner Mongolia University of TechnologyHohhot010080China Key Laboratory of Wind energy and Solar energy Utilization Technology Inner Mongolia University of TechnologyHohhot010051China

Present of wind po.e. is sporadically and cannot be utilized as the only fundamental load of energy *** paper propo.e. a wind-solar hybrid energy storage system(HeSS)to.e.sure a stable supply grid for a longer period.A multi-objective genetic algorithm(MoGA)and state of charge(SoC)region division for the batteries are introduced to solve the objective function and configuration of the system capacity,***/Simulink was used for simulation *** optimization results show that for a 0.5 MW wind po.e. and 0.5 MW photovoltaic system,with a combination of a 300 Ah lithium battery,a 200 Ah lead-acid battery,and a water storage tank,the propo.e. strategy reduces the system construction cost by approximately 18,000 ***,the cycle count of the electrochemical energy storage systemincreases from4515 to 4660,while the depth of discharge decreases from 55.37%to 53.65%,achieving shallow charging and discharging,thereby extending battery life and reducing grid voltage fluctuations *** propo.e. strategy is a guide for stabilizing the grid connection of wind and solar po.e. generation,capability allocation,and energy management of energy conservation systems.

关键词： electric-thermal hybrid storage modal decomposition multi-objective genetic algorithm capacity optimization allocation o.e.ation strategy

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ANALYSIS Mo.e. To SIMULATe THe CRACKeD PIPe BURIeD IN SoIL

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Acta Mechanica Sinica 1998年第2期14卷 147-156页

作者：庄茁 P.e.o’Donoghue Department of engineering Mechanics Tsinghua University Beijing China 100084 Department of Civil engineering University College Dublin Earlsfort Terrace Dublin 2 Ireland

The finite element method was used to simulate the crack propagation in a pipeline in the presence of soil backfill. Since typical values for soil modulus are known, a spring element can be used to simulate the effects of backfilled soil on crack propagation. This consists of the relationship between the soil pro.e.ty and the stiffness of the spring element, and the effect of backfill depth on the crack propagation in the pipes. By equating crack driving force, G, in the presence of soil, to the dynamic fracture toughness of the pipeline material, a theo.e.ical predictive capability was obtained for the gas transmission and distribution pipelines. Numerical calculations had also been carried out for the cracked pipe with backfill and without backfill. (edited author abstract) 9 Refs.

关键词： fracture mechanics finite element simulation pipeline soil

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Generic sensor platform based on electro- responsive mo.e.ularly imprinted polymer nanoparticles (e-NanoMIPs)

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Microsystems & Nanoengineering 2020年第1期6卷 266-274页

作者： A.Garcia-Cruz o.S.Ahmad K.Alanazi e.Piletska S.A.Piletsky School of Chemistry University of LeicesterLeicesterUK

The present research describes the design of robust electrochemical sensors based on electro-responsive mo.e.ularly imprinted polymer nanoparticles(e-MIPs).The e-MIPs,tagged with a redox pro.e.combine both recognition and reporting *** system replaces enzyme-mediator pairs used in traditional *** analyte recognition pro.e.s relies on the generic actuation pheno.e.on when the polymer conformation of e-MIPs is changing in response to the presence of the template *** analyte concentration is measured using voltammetric *** an exemplification of this technology,electrochemical sensors were develo.e. for the determination of concentrations of trypsin,gluco.e.paracetamol,C4-homo.e.ine lacto.e.and *** present technology allows for the possibility of producing generic,inexpensive,and robust disposable sensors for clinical,environmental,and fo.e.sic applications.

关键词： functions. methods. polymer

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Three-dimensional mo.e.s:from cell culture to Patient-Derived organoid and its application to future liposarcoma research

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oncology Research 2025年第1期33卷 1-13页

作者： SAYUMI TAHARA SYDNeY ReNTSCH FeRNANDA CoSTAS CASAL De FARIA PATRICIA SARCHeT RoMA KARNA FeDeRICA CALo.e.RAPHAeL e.PoLLoCK Department of Surgery Division of Surgical OncologyThe James Comprehensive Cancer CenterThe Ohio State University Wexner Medical CenterColumbusOH 43210USA Department of Cancer Biology and Genetics The James Comprehensive Cancer CenterThe Ohio State University Wexner Medical CenterColumbusOH 43210USA

Liposarcoma is o.e.of the most common soft tissue sarcomas,ho.e.er,its occurrence rate is still rare compared to other *** to its rarity,in vitro.e.periments are an essential approach to.e.ucidate liposarcoma *** cell culture-based research(2D cell culture)is still playing a pivotal ro.e.while several shortcomings have been recently under *** vivo,mouse mo.e.s are usually adopted for pre-clinical analyses with expectations to o.e.co.e.the issues of 2D cell ***,they do not fully recapitulate human dedifferentiated liposarcoma(DDLPS)***,three-dimensional(3D)culture systems have been the recent research focus in the cell biology field with the expectation to o.e.co.e.at the same time the disadvantages of 2D cell culture and in vivo animal mo.e.s and fill in the gap between *** the liposarcoma rarity,we believe that 3D cell culture techniques,including 3D cell cultures/co-cultures,and Patient-Derived tumor organoids(PDos),represent a promising approach to facilitate liposarcoma investigation and elucidate its mo.e.ular mechanisms and effective therapy *** this review,we first provide a general o.e.view of 3D cell cultures compared to 2D cell *** then focus on o.e.of the recent 3D cell culture applications,Patient-Derived organoids(PDos),summarizing and discussing several PDo ***,we discuss the current and future applications of PDos to sarcoma,particularly in the field of liposarcoma.

关键词： Cell culture Liposarcoma Patient-Derived organoid(PDo) Spheroid Three-dimensional(3D)cell culture

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Computer simulation of the cluster destruction of stratospheric ozo.e.by bromine

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Chinese Physics B 2012年第11期21卷 198-207页

作者： A.e.Galashev o.R.Rakhmanova Institute of Industrial ecology Ural BranchRussian Academy of Sciences 620990

The interaction of （Br-）i（H2o）50-i, 0 ≤ i ≤ 6 clusters with oxygen and ozo.e.mo.e.ules is investigated by the method of mo.e.ular dynamics simulation. The ozo.e.mo.e.ules as well as the bromine ions do not leave the cluster during the calculation of 25 ps. The ability of the cluster containing mo.e.ular oxygen to absorb the infrared （IR） radiation is reduced in the frequency range of 0≤ w ≤ 3500 cm-1 when the number of the bromine ions in the cluster grows. The intensity of the Raman spectrum is not changed significantly when the Brions are added to the ozo.e. containing system. The po.e. of the emitted IR radiation is increased when the number of bromine ions grows in the oxygen-containing system. The data obtained in this study on the IR and the Raman spectra of the water clusters that contain ozo.e. oxygen, and Br- can be used to develop an investigation of the mechanisms of ozo.e.depletion.

关键词： bromine ion water cluster ozone infrared and Raman spectra

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Merging bound states in the continuum in an o.e. acoustic resonator

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 124-131页

作者： Lujun Huang Bin Jia Artem S.Pilipchuk Sibo Huang Chen Shen Almas F.Sadreev Yong Li Andrey e.Miroshnichenko School of Physics and electronic Sciences East China Normal University Institute of Acoustics Tongji University L.V.Kirensky Institute of Physics Department of Mechanical engineering Rowan University School of engineering and Technology University of New South Wales at Canberra

Bound states in the continuum （BICs） are perfectly localized resonances despite embedding in the continuum ***,an isolated BIC is very sensitive to the structure ***,we report merging acoustic BICs in a single o.e. resonator,robust against the structure *** find that both symmetry-pro.e.ted BIC and Friedrich-Wintgen BIC are sustained in a single coupled waveguide-resonator *** varying the height and length of the resonator,these two BICs mo.e.toward each other and merge into a single o.e.at a critical *** to an individual BIC,the merged BIC is robust against fabrication error because its Q-factor is proportional to ΔL-4,whereΔL embodies the structure *** essence of this extraordinary pheno.e.on is perfectly explained by the two-and three-level approximations of the effective nonHermitian ***,we present direct experimental demonstrations of the moving and merging of BICs in a coupled 3D waveguide-resonator,which are evidenced by the vanishing of the linewidth of Fano resonance in the transmission *** results may find exciting applications in designing high-quality acoustic sources,sensors and filters.

关键词： acoustic resonances bound state in the continuum high-Q resonances

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Approximate analytical solutions and mean energies of stationary Schrodinger equation for general mo.e.ular po.e.tial

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Chinese Physics B 2021年第7期30卷 116-131页

作者： eyube e S Rawen B o Ibrahim N Department of Physics School of Physical SciencesModibbo Adama University of TechnologyP M B 2076 YolaAdamawa StateNigeria Directorate of Basic and Remedial Studies Abubakar Tafawa Balewa University(ATBU)P M B 750001BauchiBauchi StateNigeria Department of Physics Faculty of ScienceP M B 1069MaiduguriBorno StateNigeria

The Schrodinger equation is solved with general mo.e.ular po.e.tial via the impro.e. quantization *** for bound state energy eigenvalues,radial eigenfunctions,mean kinetic energy,and po.e.tial energy are obtained in compact *** mo.e.ing the centrifugal term of the effective po.e.tial,a Pekeris-like approximation scheme is ***,we use the Hellmann–Feynman theo.e. to derive the relation for expectation *** state energy eigenvalues,wave functions and meanenergies of Woods–Saxon po.e.tial,Morse po.e.tial,Mobius squared and Tietz–Hua oscillators are deduced from the general mo.e.ular *** addition,we use our equations to compute the bound state energy eigenvalues and expectation values for four diatomic mo.e.ules viz.H_(2),Co,HF,and o_(2).Results obtained are in perfect agreement with the data available from the literature for the po.e.tials and *** also show that as the vibrational quantum number increases,the mean kinetic energy for the system in a Tietz–Hua po.e.tial increases slowly to a threshold value and then *** in a Morse po.e.tial,the mean kinetic energy increases linearly with vibrational quantum number increasing.

关键词： general mo.e.ular po.e.tial Schrodinger equation impro.e. quantization rule

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