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Frequency of Bacterial Organisms Isolated from Cerebrospinal Fluid (CSF) of Children under Five Years in Windhoek from 2010 to 2014

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Open Journal of Medical Microbiology 2016年第3期6卷 125-132页

作者： Erastus Lafimana Haimbodi Munyaradzi Mukesi owen Mtambo Sylvester Rodgers Moyo Department of Health Sciences Faculty of Health and Applied Sciences Namibia University of Science and Technology Windhoek Namibia Department of Mathematics and Statistics Faculty of Health and Applied Sciences Namibia University of Science and Technology Windhoek Namibia

Bacterial meningitis (BM) is a life-threatening condition which affects the central nervous system (CNS). Its incidence rate is estimated between 0.22 - 2.66 and 0.81 - 6.1 cases/1000 lives worldwide and in Africa respectively. The objective of this study was to determine the frequency of bacterial organisms isolated from CSF of children less than five years old in Windhoek. A retrospective analysis was performed on 784 results of CSF submitted to the Namibia Institute of Pathology (NIP) from January 2010 to August 2014. The results showed that out of the suspected meningitis cases, 18 (28.6%) were due to Streptococcus pneumoniae, making it the frequently isolated organism, followed by Staphylococcus aureus 7 (11.1%), Escherichia coli 5 (7.9%) and Haemophilus influenzae 4 (6.3%). Streptococcus pneumoniae showed high resistance to penicillin 17 (70.5%) & cotrimoxazole 16 (93.7%) and 100% susceptibility to ciprofloxacin (5), vancomycin (13) & ceftri-axone (8). Haemophilus influenzae showed moderate resistance to cotrimoxazole 3 (66%) & tet-racycline 2 (50%). It showed 100% sensitivity to chloramphenicol (4), cefuroxime (2) & ceftriaxone (3). Neisseria meningitidis showed high resistance to cotrimoxazole by 100% (n = 2) and high sensitivity to chloramphenicol (n = 2), ceftriaxone & penicillin by 100% (n = 2). Streptococcus agalactiae was resistant to tetracycline and sensitive to penicillin & erythromycin by 100% (n = 1). Streptococcus pneumoniae was isolated the most in this current study and it had high resistance to penicillin & cotrimoxazole. There was a significant difference between results CSF culture and PCR, Gram stain, CSF cell count, protein & glucose, as all comparisons yielded in P values less than 0.05, indicating a significant statistical association.

关键词： Bacterial Meningitis Frequency Cerebrospinal Fluid Retrospective Namibia

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极地平流层云和臭氧洞

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气象科技 1992年第4期20卷 72-75页

作者： owen B.Toon 赵希友美国NASA Ames研究中心

1.引言极地平流层云(PSCs)对南极臭氧洞的形成及北半球臭氧的耗减是至关重要的.首先,极地平流层云通过沉降作用清除平流层中作为云的成分的氮化物.云层内低的氮化物含量。

关键词：极地平流层云臭氧洞化学反应

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Late Quaternary palaeoenvironment change and landscape evolution along the Keriya River,Xinjiang,China:the relationship between high mountain glaciation and landscape evolution in foreland desert regions

Late Quaternary palaeoenvironment change and landscape evolu...

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中国科学院地质与地球物理研究所2002学术年会

作者： D.Jaekel L.A.owen Institute of Geographical Sciences Free University BerlinGermany Department of Earth Sciences University of California

The sedimentology and geomorphology of landforms along Keriya River,that traverse the Kunlun Mountains and Taklamakan Desert,were studied to examine the relationship between environmental change and landscape evolution in mountains and desert margins of the Taklamakan *** region is divided into four geomorphic provinces:desert with active dunes and sand seas;desert pediment with fans;and foothills with deep gorges and glaciated mountains.A succession of three fans with dunes is differentiated on the basis of morphostratigraphy and relative weathering. The oldest fan and dunes are radiocarbon dated to～29 *** fan probably formed as a response to increased meltwater and sediment loads as glaciers retreated at the end of the local last glacial maximum in the Kunlun *** and glacial features throughout the region show that, during the last glacial,the snowline was lowered to～4000m a.s.l.,permafrost existed down to an altitude of～1800m a.s.l.,and that the likely temperature depression was～10℃.Radiocarbon dates on sand dunes and tamarisk hills help dune the age of the lower two terraces to>1.5 ka and a few hundred years BR This suggests that these terraces may have formed in response to increased precipitation during more humid times at～2 ka and during the Little Ice Age,*** landforms and sediments in this region are polygenetic in origin,being transported,eroded and deposited by glacial,fluvial,aeolian and lacustrine *** size characteristics show that the fluvial sediments were substantially modified down *** contrast,the aeolian sediments were modified as they were transported toward the mountains from the desert by the dominant northerly *** complex interaction between environmental change and earth surface processes provides an important framework for examining the environmental consequences of the recently growing population and intensified agricultural activities along the mountain and desert margins

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A 3D benign paroxysmal positional vertigo model for study of otolith disease

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2016年第1期2卷 -页

作者： Michael Teixido owen Woods Brian Kung Mohammad Seyyedi Christiana Care Health Systems Newark DE USA University of Montreal Canada Department of 0tolaryngology Kaiser Permanente Greater Southern Alameda CA USA

Objective:To develop a three-dimensional study tool of the membranous labyrinth in order to study the pathophysiology, diagnostic workup and treatment of benign paroxysmal posi-tional vertigo (BPPV). BPPV is the most common cause of peripheral vertigo. Its diagnosis and treat-ment depend on an understanding of the anatomy of the vestibular labyrinth and its position relative to the head. To date, many illustrations have been made to explain principals of diagnosis and treat-ment of BPPV, but few have been based on anatomical studies of the membranous labyrinth. Methods:A cadaveric human membranous labyrinth was axially sectioned at 20 mm resolution, stained and segmented to create a high-resolution digital model. The model was cloned to create an enantio-meric pair of labyrinths. These were associated a 3D model of a human skull, segmented from MRI data, and were oriented according to established anatomic norms. Canal markers representing otoliths were created to mark canalith position during movement of the model within the 3D environment. Results:The model allows visualization of true membranous labyrinth anatomy in both ears simulta-neously. The dependent portion of each semicircular duct and of the utricle can easily be visualized in any head position. Moveable markers can mark the expected progress of otolith debris with changes in head position and images can be captured to document simulations. The model can be used to simulate pathology as well as diagnostic maneuvers and treatment procedures used for BPPV. The model has great potential as a teaching tool. Conclusion:A simple model based on human anatomy has been created to allow careful study of BPPV pathophysiology and treatment. Going forward, this tool could offer insights that may lead to more ac-curate diagnosis and treatment of BPPV. Copyright a 2016 Chinese Medical Association. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. This is an open acces

关键词： Benign paroxysmal positional vertigo Modeling Anatomy Histology Model 3D

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Expression, secretion and functional characterization of three laccases in E. coli

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Synthetic and Systems Biotechnology 2022年第1期7卷 474-480页

作者： Yating Mo Hou Ip Lao Sau Wa Au Ieng Chon Li Jeremy Hu Hoi Man Yuen Wai Man Cheong owen Lok In Lo Leo Chi U.Seak Pui Ching Middle School(Macao) Edificio Pui Ching7A Av.de Horta e CostaMacao SARChina Department of Physiology Development of NeuroscienceUniversity of CambridgeCambridgeCB23DYUnited Kingdom The Centre for Inflammation Research University of Edinburgh47 Little France CrescentEdinburghEH164TJUnited Kingdom

Endocrine Disrupting Chemicals(EDCs)are a group of molecules that can influence hormonal balance,causing disturbance of the reproductive system and other health *** the efforts to eliminate EDC in the environment,all current approaches are inefficient and *** previous research,studies revealed that laccase-producing microorganisms may be a potential candidate for EDC degradation,as laccases have been found to be able to degrade many kinds of EDCs effectively and ***,we created two recombinant laccases,each fused with secretion peptide,Novel Signal Peptide 4(NSP4),and expressed them in Escherichia coli(***,BL21),together with one laccase without secretion *** first optimized the culture condition of expressing these ***,we test the activity of the recombinant laccases of decolorizing of a synthetic dye,indigo ***,we confirmed the secreted can degrade one of the EDCs,β-estradiol,showing the potential of using the laccase secretion system to degrade toxic compounds.

关键词： Laccase Endocrine disrupting chemicals(EDCs)

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英国卫生服务管理改革的趋势

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国外医学（卫生经济分册） 1992年第2期9卷 69-73页

作者： owen JW 饶辉钱海波

本文阐述了英国国家卫生服务制度(NHS)应当如何针对其面临的六个主要方面的问题进一步进行改革和发展,以及为什么解决这些紧迫的问题是卫生服务管理人员所面临的一项艰巨任务。1984年,自中央政府,到威尔士九个地区卫生局下属单位都实行... 详细信息

本文阐述了英国国家卫生服务制度(NHS)应当如何针对其面临的六个主要方面的问题进一步进行改革和发展,以及为什么解决这些紧迫的问题是卫生服务管理人员所面临的一项艰巨任务。1984年,自中央政府,到威尔士九个地区卫生局下属单位都实行了卫生服务的综合管理;这就为现行卫生服务管理体制奠定了基础,标志着卫生服务开始从原来的那种形式向主动经营形式过渡。NHS的管理人员目前必须特别重视计划安排、目标制定、政策管理、资源分配以及卫生服务的管理改革等方面的问题。1988年公布的威尔士“共同管理计划”强调基本的管理原则,并且为今后五年威尔士NHS管理工作的初步安排和最终目的提出了规化。该项计划还促进了“共同规化”方案的实施。卫生服务管理的发展趋势同1989年发布的政府白皮书“为患者服务”中所制定的NHS改革计划有着紧密的联系。本文还对威尔士推动卫生服务改革进程的一些新的做法进行了阐述。

关键词：英国卫生服务制度卫生管理改革

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Numerical investigation of the dynamics of a rigidspherical particle in a vortical cross-slot flow atmoderate inertia

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Microsystems & Nanoengineering 2023年第4期9卷 181-195页

作者： Konstantinos Kechagidis Benjamin owen Lionel Guillou Henry Tse Dino Di Carlo Timm Krüger School of Engineering Institute for Multiscale ThermofluidsUniversity of EdinburghW Mains RdEdinburgh EH93JW ScotlandUK Cytovale Inc.Executive Park Blvd.San Fransisco CA 90095 CAUSA Department of Bioengineering University of CaliforniaWestwood PlazaLos Angeles 610101 CAUSA

The study of flow and particle dynamics in microfluidic cross-slot channels is of high relevance for lab-on-a-chipapplications. In this work, we investigate the dynamics of a rigid spherical particle in a cross-slot junction for a channelheight-to-width ratio of 0.6 and at a Reynolds number of 120 for which a steady vortex exists in the junction *** an in-house immersed-boundary-lattice-Boltzmann code, we analyse the effect of the entry position of theparticle in the junction and the particle size on the dynamics and trajectory shape of the particle. We find that thedynamics of the particle depend strongly on its lateral entry position in the junction and weakly on its vertical entryposition;particles that enter close to the centre show trajectory oscillations. Larger particles have longer residencetimes in the junction and tend to oscillate less due to their confinement. Our work contributes to the understanding ofparticle dynamics in intersecting flows and enables the design of optimised geometries for cytometry and particlemanipulation.

关键词： particle dynamics spherical

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Developing a Historical Phenology Dataset through Community Involvement for Climate Change Research

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American Journal of Climate Change 2020年第1期9卷 11-22页

作者： Lori Petrauski Sheldon owen George Constantz James T. Anderson Division of Forestry and Natural Resources West Virginia University Morgantown WV USA West Virginia University Extension Service Morgantown WV USA 818 Great Plains Dr. Capon Bridge WV USA

There has been an increased effort to utilize untapped sources of historical phenological data such as museum specimens, journals written by nature-minded citizens, and dated photographs through local phenology projects for climate change research. Local phenology projects have contributed greatly to our current understanding of phenological changes over time and have an important role in the public’s engagement with natural history, but there are also significant challenges in finding and analyzing historical data. The West Virginia Climate History Project collected historical phenology data (1890-2015) from citizens in West Virginia with scientific and cultural results. We discuss the development of the project, issues we overcame, recommendations for future projects, and the conservation value of local phenology projects. Local phenology projects lend value to climate change research and conservation education. Policy directed towards supporting humanities grants and museum collections, including herbariums, is crucial in the success of these projects.

关键词： Historical Phenology Community Phenology Citizen Science Conservation Phenology

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2009最美

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汽车杂志 2009年第12期 194-203页

作者： owen

2009，是很不平凡的一年，在2008经过了各种重创后，我们看到的是人类更强更快的修复能力，金钱、斗争和美，是我们永恒讨论的三大主题，此时我们更多关注最后一个。

关键词：轿车车模 2009年编辑部

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数字机顶盒的架构与设计关键

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电子产品世界 2006年第9S期13卷 64-72页

作者： owen 中国台湾

数字电视可说是手机之外的另一波杀手级应用,它以客厅为核心,不断地整合家庭中的其它视听及信息设备,形成多元应用的家庭网络;不仅如此,数字电视与手机也向整合之路发展,移动电视(Mobile TV)已在全球各地如火如茶的推动当中.当电视广播... 详细信息

数字电视可说是手机之外的另一波杀手级应用,它以客厅为核心,不断地整合家庭中的其它视听及信息设备,形成多元应用的家庭网络;不仅如此,数字电视与手机也向整合之路发展,移动电视(Mobile TV)已在全球各地如火如茶的推动当中.当电视广播系统与网络、甚至是移动蜂窝系统结合时,包括视频、语音与数据的服务自然走向多元汇流的趋势,这是一个比过去独立形式复杂许多的应用环境,而数字机上盒(Settop-box)正位于此架构的核心位置,其面临的设计挑战确实繁重.

关键词：数字机顶盒设计架构家庭网络电视广播系统移动蜂窝系统数字电视信息设备

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