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Effect of Relaxing Needling plus Rehabilitation Training on Post-stroke Upper Limb Dysfunction

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Journal of Acupuncture and Tuina Science 2014年第3期12卷 146-149页

作者： Yao Wen-juan ouyang ba-si Hong Jue The Second School of Clinical Medicine Nanjing University of Chinese Medicine Department of Acupuncture Suzhou Hospital of Traditional Chinese Medicine

Objective: To observe the effect of relaxing needling plus rehabilitation training on post-stroke upper limb dysfunction. Methods: sixty-eight eligible subjects with post-stoke upper limb dysfunction were randomized into 2 groups by the random number table, 34 in each group, to respectively receive relaxing needling method or ordinary needling method in addition to rehabilitation training for 2 months. Fugl-Meyer assessment of upper limb motor function, neurological defect score, and clinical efficacies were observed and compared. Results: The two groups both showed effects. The total effective rate in the relaxing needling group was 93.8% versus 84.9% in the ordinary needling group, and the difference was statistically significant(Psion: Relaxing needling plus rehabilitation training can significantly improve the post-stroke motor dysfunction of upper limb, better than ordinary needling plus rehabilitation training.

关键词：针灸治疗刺破方法击复杂并发症上面的极限康复 R246.6

Carbon dots-derived three-dimensional-ordered macroporous host with high penetrability and catalytic activity for LSBs under lean electrolyte

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Rare Metals 2024年第6期43卷 2560-2573页

作者： Jiao-Zi Duan Hua-Yu Pei Quan Yang Xue Li Xin ba Xue Yong Jun-Ling Guo si-Yu Lu Green Catalysis Center College of ChemistryZhengzhou UniversityZhengzhou 450001China Country State Center for International Cooperation On Designer Low-Carbon&Environmental Materials School of Materials Science and EngineeringZhengzhou UniversityZhengzhou 450001China Hubei Institute of Quality Supervision Inspection Wuhan 430061China Department of Chemistry University of SheffieldSheffeld S37HFUK

The practical energy density of lithium-sulfur batteries(LSBs)is seriously limited by the high electrolyte-to-sulfur ratios(E/S).The E/S can be reduced by employing hosts with easy-to-infiltrate structure that ensures the uniform distribution of a lean electrolyte and high catalytic activity that can suppress"shuttle effect"via accelerating the slow conversion of soluble poly sulfides to insoluble *** the easy-to-infiltrate structures,the three-dimensional-ordered macroporous(3DOM)structure is easier to scale preparation and more suitable for the existing industrial ***,it is difficult to obtain the 3DOM with(1)high penetrability due to the high viscosity of frequently-used organic polymer precursors and(2)high catalytic activity due to the low confinement effect,meaning that uniformly dispersed small-sized catalytic materials are difficult to load on ***,using carbon dots(CDs)with both organic and inorganic properties as a precursor and aggregation limiting agent,a 3DOM host with high penetrability and homodispersed Ni particles of small sizes(Ni-CDs-3DOM)was *** this host:(1)CDs precursor with suitable viscosity can improve the penetrability.(2)CDs can effectively inhibit the agglomeration of Ni particles.(3)Uniformly dispersed small-size Ni particles offer high-efficiency catalytic activity toward sulfur ***,the Ni-CDs-3DOM/sulfur cathode exhibits high sulfur utilization and stable cycling performance even under high sulfur loading(5.5 mg·cm^(-2))and low E/S(6.5μl·mg^(-1)).This work indicates the usefulness of CDs in constructing hosts for LSBs with high energy density.

关键词： Lithium-sulfur batteries Carbon dots Catalytic action Easy-to-infiltrate structure Lean electrolyte

A signaling cascade mediating fruit trait development via phosphorylation-modulated nuclear accumulation of JAZ repressor

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Journal of Integrative Plant Biology 2024年第6期66卷 1106-1125页

作者： Wei Wang Jinyao ouyang Yating Li Changsheng Zhai Bing He Huahan si Kunsong Chen Jocelyn K.C.Rose Wensuo Jia College of Horticulture China Agricultural UniversityBeijing 100193China College of Agriculture and Biotechnology Zhejiang UniversityZijingang CampusHangzhou 310058China Plant Biology Section School of Integrative Plant ScienceCornell UniversityIthaca14853NYUSA Institute of Horticulture Crops Xinjiang Academy of Agricultural SciencesUrumqi 830000China

It is generally accepted that jasmonate-ZIM domain(JAZ)repressors act to mediate jasmonate(JA)signaling via CORONATINE-INSENsiTIVE1(COI1)-mediated ***,we report a cryptic signaling cascade where a JAZ repressor,FvJAZ12,mediates multiple signaling inputs via phosphorylation-modulated subcellular translocation rather than the COI1-mediated degradation mechanism in strawberry(Fragaria vesca).FvJAZ12 acts to regulate flavor metabolism and defense response,and was found to be the target of Fv MPK6,a mitogen-activated protein kinase that is capable of responding to multiple signal ***6 phosphorylates FvJAZ12 at the amino acid residues S179 and T183 adjacent to the PY residues,thereby attenuating its nuclear accumulation and relieving its repression for FvMYC2,which acts to control the expression of lipoxygenase 3(FvLOX3),an important gene involved in JA biosynthesis and a diverse array of cellular *** data reveal a previously unreported mechanism for JA signaling and decipher a signaling cascade that links multiple signaling inputs with fruit trait development.

关键词： defense response JAZ repressor phosphorylation strawberry subcellular translocation

Exploring cerebral structural and functional abnormalities in a mouse model of post-traumatic headache induced by mild traumatic brain injury

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Zoological Research 2024年第3期45卷 648-662页

作者： Dan Yang Bin-Bin Nie Jin-Gang He Zong-Qiang Lv Feng-Feng Mo si-Yi ouyang Jie Wang Ju-Xiang Chen Tao Tao Department of Anesthesiology Central People’s Hospital of ZhanjiangZhanjiangGuangdong 524045China Key Laboratory of Nuclear Radiation and Nuclear Energy Technology Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China Key Laboratory of Magnetic Resonance in Biological Systems State Key Laboratory of Magnetic Resonance and Atomic and Molecular PhysicsNational Center for Magnetic Resonance in WuhanWuhan Institute of Physics and MathematicsInnovation Academy for Precision Measurement Science and TechnologyChinese Academy of Sciences-Wuhan National Laboratory for OptoelectronicsWuhanHubei 430071China Department of Neurosurgery Changhai HospitalNaval Medical UniversityShanghai 200082China Department of Nutrition and Food Hygiene Faculty of Naval MedicineNaval Medical UniversityShanghai 200433China Department of Anesthesiology Nanfang HospitalSouthern Medical UniversityGuangzhouGuangdong 510515China Institute of Neuroscience and Brain Diseases/Xiangyang Central Hospital Affiliated Hospital of Hubei University of Arts and ScienceXiangyangHubei 441021China Songjiang Hospital and Songjiang Research Institute Shanghai Jiao Tong University School of MedicineShanghai 201600China Department of Anesthesiology Zhujiang HospitalSouthern Medical UniversityGuangzhouGuangdong 510515China

Mild traumatic brain injury(mTBI)-induced post-traumatic headache(PTH)is a pressing public health concern and leading cause of disability *** PTH is often accompanied by neurological disorders,the exact underlying mechanism remains largely *** potential biomarkers may prompt the diagnosis and development of effective treatments for mTBI-induced *** this study,a mouse model of mTBI-induced PTH was established to investigate its effects on cerebral structure and function during short-term *** indicated that mice with mTBI-induced PTH exhibited balance deficits during the early post-injury *** kinetics revealed that variations in neurotransmitters were most prominent in the cerebellum,temporal lobe/cortex,and hippocampal regions during the early stages of ***,variations in brain functional activities and connectivity were further detected in the early stage of PTH,particularly in the cerebellum and temporal cortex,suggesting that these regions play central roles in the mechanism underlying ***,our results suggested that GAba and glutamate may serve as potential diagnostic or prognostic biomarkers for *** studies should explore the specific neural circuits involved in the regulation of PTH by the cerebellum and temporal cortex,with these two regions potentially utilized as targets for non-invasive stimulation in future clinical treatment.

关键词： Post-traumatic headache(PTH) Mild traumatic brain injury(mTBI) Metabolic kinetics fMRI Cerebellum

Yinhuang granule alleviates carbon tetrachloride-induced liver fibrosis in mice and its mechanism

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World Journal of Hepatology 2024年第2期16卷 264-278页

作者： Hao ouyang Hui Miao Zhen Li Duan Wu si-Cheng Gao Yao-Yao Dai Xiao-Di Gao Hai-Sheng Chai Wei-Ye Hu Jun-Feng Zhu Department of Liver Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghai 201203China State Key Laboratory of Bioreactor Engineering East China University of Science and TechnologyShanghai 201203China

baCKGROUND Liver fibrosis is a formidable global medical challenge,with no effective clinical treatment currently *** granule(YHG)is a proprietary Chinese medicine comprising Scutellariae Radix and Lonicerae Japonicae *** is frequently used for upper respiratory tract infections,pharyngitis,as well as acute and chronic *** To investigate the potential of YHG in alleviating carbon tetrachloride(CCl4)-induced liver fibrosis in *** To induce a hepatic fibrosis model in mice,this study involved intraperitoneal injections of 2 mL/kg of CCl4 twice a week for 4 ***,liver fibrosis mice in the low dose of YHG(0.4 g/kg)and high dose of YHG(0.8 g/kg)groups were orally administered YHG once a day for 4 *** alanine/aspartate aminotransferase(ALT/AST)activity and liver hydroxyproline content were *** red and Masson's trichrome staining assay were *** polymerase chain reaction,western-blot and enzyme-linked immunosorbent assay were *** glutathione content,superoxide dismutase activity level,reactive oxygen species and protein carbonylation amount were *** The administration of YHG ameliorated hepatocellular injury in CCl4-treated mice,as reflected by decreased serum ALT/AST activity and improved liver histological *** also attenuated liver fibrosis,evident through reduced liver hydroxyproline content,improvements in sirius red and Masson's trichrome staining,and lowered serum hyaluronic acid ***,YHG hindered the activation of hepatic stellate cells(HSCs)and ameliorated oxidative stress injury and inflammation in liver from CCl4-treated *** prompted the nuclear accumulation of nuclear factor erythroid 2-related factor 2(Nrf2)and upregulated the expression of Nrf2-dependent downstream antioxidant *** addition,YHG promoted mitochondrial biogenesis in liver from CCl4-treated mice,as demonstrated by increased liver adenosine triphosphate content,

关键词： Yinhuang granule Liver fibrosis Hepatic stellate cells Oxidative injury Nuclear factor erythroid 2-related factor 2 Inflammation

Total body water percentage and 3rd space water are novel risk factors for training-related lower extremity muscle injuries in young males

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Chinese Journal of Traumatology 2024年第3期27卷 168-172页

作者： Liang Chen Ke-Xing Jin Jing Yang Jun-Jjie ouyang Han-Gang Chen si-Ru Zhou Xiao-Qing Luo Mi Liu Liang Kuang Yang-Li Xie Yan Hu Lin Chen Zhen-Hong Ni Xiao-Lan Du Department of Orthopedic Daping HospitalArmy Medical UniversityChongqing400042China Department of Rehabilitation Medicine Daping HospitalArmy Medical UniversityChongqing400042China Department of Wound Repair and Rehabilitation Medicine Center of Bone Metabolism and RepairLaboratory for Prevention and Rehabilitation of Training InjuriesState Key Laboratory of Trauma and Chemical Poisoning.Trauma CenterResearch Instiute of SurgeryDaping HospitalArmy Medical UniversityChongqing.400042China War Trauma Medical Center Daping HospitalArmy Medical UniversityChongqing400042.China Department of Military basic Training and Army Management Army Health Service Training BaseArmy Medical UniversityChongqing400042China Department of Army Occupational Disease Laboratory for Prevention and Rehabilitation of Training InjuriesState Key Laboratory of Trauma and Chemical PoisoningResearch Institute of SurgeryDaping HospitalArmy Medical UniversityChongqing400042.China

Purpose:To identify the risk factors for training-related lower extremity muscle injuries in young males by a non-invasive method of body composition ***:A total of 282 healthy young male volunteers aged 18-20 years participated in this cohort *** location,degree,and injury rate were adjusted by a questionnaire based on the overuse injury assessment methods used in epidemiological studies of sports *** occurrence of training injuries is monitored and diagnosed by physicians and treated *** body composition was measured using the BodyStat QuadScan 4000 multifrequency Bio-impedance system at 5,50,100 and 200 kHz to obtain 4 impedance *** Shapiro-Wilk test was used to check whether the data conformed to a normal *** of normal distribution were shown as mean±SD and analyzed by t-test,while those of non-normal distribution were shown as median(Q1,Q3)and analyzed by Wilcoxon rank sum *** receiver operator characteristic curve and logistic regression analysis were performed to investigate risk factors for developing training-related lower extremity injuries and ***:Among the 282 subjects,78(27.7%)developed training *** extremity training injuries revealed the highest incidence,accounting for 23.4%(66 cases).These patients showed higher percentages of lean body mass(p=0.001),total body water(TBW,p=0.006),extracellular water(p=0.020)and intracellular water(p=0.010)as well as a larger ratio of basal metabolic rate/total weight(p=0.006),compared with those without lower extremity muscle *** the contrary,the percentage of body fat(p=0.001)and body fat mass index(p=0.002)were *** regression analysis showed that TBW percentage>65.35%(p=0.050,odds ratio=3.114)and 3rd space water>0.95%(p=0.045,odds ratio=2.342)were independent risk factors for lower extremity muscle ***:TBW percentage and 3rd space water measured with bio-impedance method are potential ris

关键词： Body composition Training injuries Lower extremity Bio-impedance

simultaneously achieving high energy density and responsivity in submicron baTiO_(3) film capacitors integrated on si

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Journal of Advanced Ceramics 2024年第2期13卷 198-206页

作者： Jun ouyang Yinxiu Xue Chuanqi Song Meiling Yuan Kun Wang Yuyao Zhao Hongbo Cheng Hanfei Zhu Chao Liu Institute of Advanced Energy Materials and Chemistry School of Chemistry and Chemical EngineeringQilu University of Technology(Shandong Academy of Sciences)Jinan 250353China Key Laboratory of Key Film Materials&Application for Equipment School of Material Sciences and EngineeringXiangtan UniversityXiangtan 411105China School of Materials Science and Engineering Shandong UniversityJinan 250061China Academic Affairs Office Civil Aviation University of ChinaTianjin 300300China China Tobacco Shandong Industrial Co. Ltd.Jinan 250014China

In the research field of energy storage dielectrics,the“responsivity”parameter,defined as the recyclable/recoverable energy density per unit electric field,has become critically important for a comprehensive evaluation of the energy storage capability of a *** this work,high recyclable energy density and responsivity,i.e.,W_(rec)=161.1 J·cm^(-3) and ξ=373.8 J·(kV·m^(2))^(-1),have been simultaneously achieved in a prototype perovskite dielectric,baTiO_(3),which is integrated on si at 500℃ in the form of a submicron thick *** ferroelectric film features a multi-scale polar structure consisting of ferroelectric grains with different orientations and inner-grain ferroelastic domains.A LaNiO_(3) buffer layer is used to induce a{001}textured,columnar nanograin microstructure,while an elevated deposition temperature promotes lateral growth of the nanograins(in-plane diameter increases from~10-20 nm at lower temperatures to~30 nm).These preferably oriented and periodically regulated nanograins have resulted in a small remnant polarization and a delayed polarization saturation in the film’s P-E behavior,leading to a high recyclable energy ***,an improved polarizability/dielectric constant of the baTiO_(3) film has produced a much larger maximum polarization than those deposited at lower temperatures at the same electric field,leading to a record-breaking responsivity for this simple perovskite.

关键词： energy storage energy density responsivity baTiO_(3) dielectric capacitor si

液质联用色谱法同时测定降糖类中成药中9种非法添加的化学成分

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中国实验方剂学杂志 2016年第19期22卷 66-69页

作者：孟丽陈伟欧阳八四盐城卫生职业技术学院江苏盐城224006 苏州市中医医院苏州市吴门医派研究院江苏苏州215009

目的:建立高效液相色谱法同时测定降糖类中成药中9种非法添加的化学成分。方法:采用C18色谱柱,以甲醇-0.1 mol·L^(-1)乙酸铵溶液梯度洗脱,检测波长235 nm,柱温35℃,同时进行全波长扫描(190~400 nm),并对可疑成分进行质谱确认。结果:9... 详细信息

目的:建立高效液相色谱法同时测定降糖类中成药中9种非法添加的化学成分。方法:采用C18色谱柱,以甲醇-0.1 mol·L^(-1)乙酸铵溶液梯度洗脱,检测波长235 nm,柱温35℃,同时进行全波长扫描(190~400 nm),并对可疑成分进行质谱确认。结果:9种对照品在各自浓度范围内,呈现良好的线性关系(r≥0.999 9),精密度、稳定性、检出限、定量限、回收率均符合规范,并检出降糖宁中非法添加了格列本脲。结论:该方法简便快速准确,适用于上述降糖类化学成分的检测。

关键词：中成药非法添加降糖类化学成分高效液相色谱-质谱联用

Dielectric ultracapacitors based on columnar nano-grained ferroelectric oxide films with gradient phases along the growth direction

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Journal of Advanced Ceramics 2024年第7期13卷 1072-1079页

作者： Chuanqi Song Feifan Zheng Yuan Zhang Hongbo Cheng Long Teng Kun Wang Hanfei Zhu Chao Liu Li Wang Zhengyan Liang Jun ouyang Institute of Advanced Energy Materials and Chemistry School of Chemistry and Chemical EngineeringQilu University of Technology(Shandong Academy of Sciences)Jinan 250353China Department of Materials Science and Engineering Southern University of Science and TechnologyShenzhen 518055China Key Laboratory of Key Film Materials&Application for Equipment(Hunan Province) School of Materials Science and EngineeringXiangtan UniversityXiangtan 411105China China Tobacco Shandong Industrial Co. Ltd.Jinan 250104China

In this work,dielectric ultracapacitors were designed and fabricated using a combination of phase boundary and nanograin *** ultracapacitors are based on submicron-thick ba(Zr_(0.2)Ti_(0.8))O_(3) ferroelectric films sputterdeposited on si at 500℃.With a composition near a polymorphic phase boundary(PPB),a compressive strain,and a high nucleation rate due to the lowered deposition temperature,these films exhibit a columnar nanograined microstructure with gradient phases along the growth *** a microstructure presents three-dimensional polarization inhomogeneities on the nanoscale,thereby significantly delaying the saturation of the overall electric ***,a pseudolinear,ultraslim polarization(P)-electric field(E)hysteresis loop was obtained,featuring a high maximum applicable electric field(~5.7 MV/cm),low remnant polarization(~5.2μC/cm^(2))and high maximum polarization(~92.1μC/cm^(2)).This P-E loop corresponds to a high recyclable energy density(Wrec~208 J/cm^(3))and charge‒discharge efficiency(~88%).An indepth electron microscopy study revealed that the gradient ferroelectric phases consisted of tetragonal(T)and rhombohedral(R)polymorphs along the growth direction of the *** T-rich phase is abundant near the bottom of the film and gradually transforms into the R-rich phase near the *** films also exhibited a high Curie temperature of~460℃and stable capacitive energy storage up to 200℃.These results suggest a feasible pathway for the design and fabrication of high-performance dielectric film capacitors.

关键词： ferroelectric thin films energy storage phase coexistence nanograin silicon