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Novel Mannich Bases of Benzimidazole Derivatives: An Antibacterial Study of Environmental Bacterial Strains

Advances in Biological Chemistry 2023年第5期13卷 182-191页

作者： Evrard Ablo Ouehi Dosso Bakary coulibaly Kouassi Franscesco Adingra Penayori Marie-Aimée coulibaly Armand Patrick Achi Tchambaga Etienne Camara Souleymane coulibaly Siomenan Coulibali Laboratoire de Constitution et Réaction de la Matière UFR Sciences des Structures de la Matière et Technologie Université Félix Houphou&#235t-Boigny de Cocody Abidjan C&#244te d’Ivoire Laboratoire des Procédés Industriels de Synthèse de l’Environnement et des énergies Nouvelles (LAPISEN) Institut National Polytechnique Félix Houphou&#235t-Boigny Yamoussoukro C&#244te d’Ivoire Laboratoire d’Agrovalorisation Département de Biochimie-Microbiologie UFR Agroforesterie Université Jean Lorougnon Guédé Daloa C&#244te d’Ivoire

A previous study was conducted on the synthesis and antibacterial evaluation of Mannich bases of 2-(thioalkyl)-1H-methylbenzimidazole derivatives. The results of this study showed that certain 2-(thioalkyl)-1H-methylbenzimidazole and 2-(thioalkyl)-methyl-1-(piperidin-1-ylmethyl)benzimidazole derivatives possess antibacterial activities against clinical strains, such as Escherichia coli, Klebsiella pneumonia (Gram-negative bacteria), Staphylococcus aureus and Pseudomonas aeruginosa (Gram-positive bacteria). Following these favorable results, we extended the antibacterial evaluation of this series of molecules to environmental strains. The aim of this study was to assess the impact of the methyl-piperidine group fixed at position-1 of this new series of benzimidazoles on the antibacterial activity of environmental strains. In addition, we first evaluated the antibacterial activity of four 2-(thioalkyl)methylbenzimidazole derivatives and then that of five 2-(thioalkyl)-methyl-1-(piperidin-1-ylmethyl) benzimidazole derivatives. This study allowed us to show that compounds 1d and 1e could inhibit bacterial growth in vitro of the Enterobacteria P1 strain with inhibition diameters of 17.3 ± 0.6 mm and 10 ± 0.0 mm, respectively. However, addition of methyl-piperidinyl in this series showed that five (5) of 2-(thioalkyl)-methyl-1-(piperidin-1-ylmethyl) benzimidazole derivatives had an inhibitory effect on the in vitro growth of bacterial strains used except on Enterobacteria P2 with inhibition diameters between 10.0 ± 0.8 mm and 27.9 ± 1.4 mm. The introduction of the methyl-piperidinyl group at the 1-position of 2-(thioalkyl)-1H-methylbenzimidazole derivatives greatly improved the antibacterial activity against environmental bacteria such as Escherichia coli A1, A2, A3, and A4 and two Enterobacteria P1.

关键词： Methylbenzimidazole Derivatives Inhibit Bacterial Growth Mannich Base Enterobacteria Escherichia coli

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Determinants of Agroecological Practices Adoption in the Sudano-Sahelian Zone

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Journal of Environmental Protection 2019年第7期10卷 900-918页

作者： Aboubacar coulibaly Mikael Motelica-Heino Edmond Hien University of Orleans Orleans France University Ouaga I Pr Joseph Ki-Zerbo Ougadougou Burkina Faso Research Institute for Development Ouagadougou Burkina Faso

Under the combined effect of both climatic and anthropogenic factors, agroecosystems and especially arable soils undergo a worrying and fast degradation in the Sudano-Sahelian zone of Western Africa threatening its socio-economic development. Food systems need to be better managed to be more resilient, to increase agricultural production, while conserving natural resources and biodiversity. Agroecological practices alternatively with traditional cultural techniques have been locally experimented to cope with local pedoclimatic constraints such as weak (low) soil fertility and climate change, increasing food demand and economic conditions. Our work aims at by taking stock of agroecological knowledge as well as the determinants of their adoption with small-scale farmers in Eastern Burkina Faso. A survey (48 farmers) was conducted in Sampieri (Kantchari district), and Logit model was used to determine equations for agroecological practices adoption. Results show that traditional production practices for millet-bean cultural systems are gradually being replaced by those of agroecological. In fact, 60.4% of producers have participated in at least one agroecological training session and 60.8% of producers are interested at least in one agroecological topic. The most adopted and practiced techniques were superficial plowing, stone-rows, zai and compost, single or in combination (60% of the producers). Determinants of these practices adoption were the increased crop yields, improved of producers’ incomes, the provision or otherwise of material and human resources and training. Additionally, variables such as training, possession of agricultural equipment were positively correlated to the adoption of agroecological practices while illiteracy impacts negatively and significantly this adoption. Moreover, agroecological practices had a significant effect on grain and straw yields of sorghum, thus confirming producers’ claims about the improvements in production observed followi

关键词： Agroecological Practices Adoption Determinants Traditional Practices Burkina Faso

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Numerical Modelling of Coupled Heat and Mass Transfer in Porous Materials: Application to Cinder Block Bricks

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Open Journal of Applied Sciences 2024年第9期14卷 2360-2373页

作者： Benjamin Kiema Ousmane coulibaly Xavier Chesneau Belkacem Zeghmati Laboratory of Environmental Physics and Chemistry (LPCE) Department of Physics Joseph KI-ZERBO University Ouagadougou Burkina Faso Laboratory of Modelling Pluridisciplinary and simulation (LAMPS) University of Perpignan Via Domitia Perpignan France

In this work, we present numerical modelling of coupled heat and mass transfer within porous materials. Our study focuses on cinder block bricks generally used in building construction. The material is assumed to be placed in air. Moisture content and temperature have been chosen as the main transfer drivers and the equations governing these transfer drivers are based on the Luikov model. These equations are solved by an implicit finite difference scheme. A Fortran code associated with the Thomas algorithm was used to solve the equations. The results show that heat and mass transfer depend on the temperature of the air in contact with the material. As this air temperature rises, the temperature within the material increases, and more rapidly at the material surface. Also, thermal conductivity plays a very important role in the thermal conduction of building materials and influences heat and mass transfer in these materials. Materials with higher thermal conductivity diffuse more heat.

关键词： Numerical Modelling Coupled Transfer Building Materials Luikov Model Finite Differences

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Kinetic and Thermodynamic Study of the Dephosphation of Wastewater by Clay Materials from Côte d’Ivoire

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Open Journal of Applied Sciences 2021年第12期11卷 1307-1323页

作者： Ake Ake Pierre Kedi Atolé Brice coulibaly Vamoussa Laboratoire de Constitution et Réaction de la Matière UFR SSMT Université Félix Houphou&#235t-Boigny Abidjan C&#244te d’Ivoire Laboratoire des Sciences et Technologies de l’environnement UFR Environnement Université Jean Lorougnon Guédé Daloa C&#244te d’Ivoire

Phosphorus is introduced into the aquatic environment from different point sources, mainly by domestic and industrial wastewater;contributing to the eutrophication of water bodies. The most common way for wastewater dephosphation is the injection of expensive chemicals into these bodies of water. Thus, the main objective of this work was to find an alternative to chemicals by using clay materials from Côte d’Ivoire to adsorb phosphate ions from aqueous solutions. The clay samples, taken from various regions were characterized by X-ray diffraction. They have a different mineralogical composition. The influence of various parameters such as the pH of the medium, contact time, the ion force, temperature, etc. on the adsorption was studied. Adsorption is influenced by the temperature, the pH of the medium, valence of the saturated cation and the clay composition. It is described by a kinetic model of the pseudo-second order. The salt of the medium has no significant effect on the process. The thermodynamic study revealed that adsorption is spontaneous, endothermic and that it is done by electrostatic means of physical nature.

关键词： Adsorption Clay Phosphate Eutrophication Wastewater Kinetic Isotherm

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Design of an Intelligent System for Automatic Detection and Location of Potholes in Mali

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Open Journal of Applied Sciences 2024年第11期14卷 3237-3242页

作者： Bourama coulibaly Daouda Camara Drissa Traore Fadaba Danioko Electrical Engineering Department Normal School of Technical and Vocational Education (ENETP) Bamako Mali Robotics and Artificial Center Bamako Mali

Potholes are practically present on all roads in Mali. Malian drivers seek to locate potholes on the road when driving. And during night trips in Mali, it is very difficult to locate potholes on the road, which most often leads to fatal accidents. The objective of this article is to design an intelligent system for detecting and locating potholes and speed bumps in Mali. For pothole detection, an ultrasonic sensor was used with an Arduino microcontroller. GPS was used to locate the location of potholes and GSM (Global System for Mobile Communication) was used to transmit the location data of potholes. Detecting potholes helps reduce the number of traffic accidents in Mali and their locations will allow local and government structures to quickly repair the road. This project has enabled an improvement in human comfort in the existing system, so that the driver can be fully attentive and reassured when driving in Mali.

关键词： Ultrasonic Sensor GPS GSM Potholes Accidents

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Potential for Green Hydrogen Production from Biomass, Solar and Wind in Togo

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Smart Grid and Renewable Energy 2022年第2期13卷 17-27页

作者： Mawunyo Simon Pierre Kitegi Yendoube Lare Ousmane coulibaly WASCAL Alumni School of Informatics for Climate Change Ouagadougou Burkina Faso Solar Energy Laboratory Physics Department Université de Lomé Lomé Togo Laboratory of Physics and Environment Chemistry School of Informatics for Climate Change Université Joseph Ki-Zerbo Ouagadougou Burkina Faso

Potential of green hydrogen producing from biomass, solar and wind in Togo has been performed. The availability of these three resources has been depicted with maps showing them per cantons in Togo, thus, by using the datasets from ESA Biomass Climate Change Initiative, the global solar atlas and the global wind atlas. The conversions rates used were: for solar resource, 3% of land was allocated for the analysis after removing the exclusions with a conversion rate of 52.5 kWh/kg of hydrogen;for biomass hydrogen, the conversion rate of 13.4 kg BS/kg H2 was assumed. Wind resources at 50 m above ground were not sufficient to evaluate the potential as it is lower than class 3 winds. QGIS version 3.6.4 and R version 4.0.4 were used. Results showed that biomass is the leading resource for producing green hydrogen from renewable energy resources;with good impact in these two cantons: Bassar, Gobe/ Eketo/Gbadi N’Kugna. However, this resource is still decreasing and in some cantons it is null.

关键词： Green Hydrogen Potential Solar Wind Biomass Climate Change

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Performance Evaluation of Asphalt Concrete Based on Basalt Aggregates of Diack and Quartzite of Bakel

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Open Journal of Civil Engineering 2023年第4期13卷 695-705页

作者： Mory coulibaly Makhaly Ba Macodou Thiam Babacar Diouf University Institute of Technology University Iba Der Thiam of Thiès Thiès Senegal UFR Engineering Sciences University Iba Der Thiam of Thiès Thiès Senegal

In Senegal, basalt aggregates are the aggregates used for the production of asphalt. They are also in some condition in base layer. However, the only licensed and operated basalt quarry in the west-central part of the country is finished and has reached very important depths thus constituting an environmental threat. This is how quartzite present in the east of the country precisely in the department of Bakel would constitute an alternative to basalt. For this purpose, the performance of two bituminous concretes based on quartzite and basalt was compared. One is made from Diack basalt aggregates, considered as the reference aggregate for asphalt in Senegal and the other is based on Bakel quartzite aggregates, they are both class 0/14. The mechanical performance of two bituminous concretes is evaluated using the Marshall method. The results obtained from the marshall tests give compactness values between 94% and 97% representing the limits laid down in the technical specifications, the creep values for quartzite-based asphalt concrete, while respecting the limit values, are higher than those obtained with basalt aggregates. Thus showing that the former is less resistant to deformation than the former. For both bituminous mixtures, the stability values remain above the minimum value of 1000 kgf set by the specifications. The water resistance test carried out on the two bituminous concretes based on basalt aggregate and quartzite aggregate gives values of immersion/compression ratio (R’c/Rc) equal to 0.72 and 0.82 respectively. These values are above the minimum required value (0.70) in the technical specifications in Senegal.

关键词： Quartzite Basalt Bituminous Concrete Marshall Duriez

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基于BEST-method估算紫色土坡耕地不同施肥和耕作管理下的土壤水力特性

基于BEST-method估算紫色土坡耕地不同施肥和耕作管理下的土壤水...

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作者： Seydina Mohamed coulibaly 西南大学

学位级别：硕士

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Right Testicle Ectopy Associated with Left Renal Agenesis

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Surgical Science 2019年第7期10卷 217-221页

作者： Mamadou Tidiani coulibaly Ousmane Koné Moumine Zié Diarra Amadou Berthé Lahassana coulibaly Zanafon Ouattara Urologist at the Gabriel Touré University Hospital Centre Bamako Mali

Testicular ectopia is a rare genital malformation belonging to the spectrum of testicular migration abnormalities. Renal agenesis can be unilateral or bilateral, isolated or associated with other malformations (1/4 of renal agenesis is accompanied by genital malformations, and more often affects the left kidney. Few cases are reported in the literature. We report a case in a 28-year-old patient with ectopia of the right testicle in the suprapubic position associated with agenesis of the left kidney, and surgical management consisted of an orchiectomy, with good surgical results.

关键词： Testis Agenesis Kidney Migration

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Thermal Modeling of a Multilayer Integrated LC Filter for Temperature Distribution Calculation

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Engineering（科研） 2019年第11期11卷 759-767页

作者： Somo coulibaly Diby Kadjo Ambroise Loum Georges Institut National Polytechnique UMRI EEA (LARIT-SISE) Yamoussoukro Ivory Coast Université Félix Houphouët-Boigny SSMT (LPMCT) Abidjan Ivory Coast

Thermal behavior of integrated passive components has become an important issue when designing these components. This paper presents the thermal modeling of a multilayer integrated LC filter used in DC-DC step-down converter for temperature distribution calculation. The approach used for this analysis is based on thermal equivalent circuit. Temperature distribution is obtained from algebraic equation, which is in vector and matrix form. The results of analytical calculation are compared with simulation results from finite element method. These results showed a good correlation.

关键词： Thermal Modeling Integrated LC Filter Temperature Distribution F. E. M. Simulation

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