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Metabolomics for quality assessment of poultry meat and eggs

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Food Quality and Safety 2024年第1期8卷 27-40页

作者： M.S.Yogeswari Jinap Selamat Nuzul Noorahya Jambari Alf khatib Mohd Hishammfariz Mohd Amin Suganya Murugesu Laboratory of Food Safety and Food Integrity Institute of Tropical Agriculture and Food SecurityUniversiti Putra MalaysiaSerdangSelangor Darul EhsanMalaysia Department of Food Science Faculty of Food Science and TechnologyUniversiti Putra MalaysiaSerdangSelangor Darul EhsanMalaysia Department of Pharmaceutical Chemistry Kulliyyah of PharmacyInternational Islamic University MalaysiaKuantanPahang Darul MakmurMalaysia Faculty of Pharmacy Airlangga UniversitySurabayaIndonesia Department of Veterinary Service Malaysia Federal Government Administration CentrePutrajayaMalaysia

The poultry industry is experiencing rapid growth *** accelerated growth has led to multiple food fraud incidents across the food supply chain,which consequently created a demand for precise determination of quality poultry *** increase in demand for precise poultry production quality has necessitated advanced *** has emerged as a viable solution by offering detailed differentiation of biochemical indicators throughout the poultry supply ***,this study provides a means to address risk factors affecting the poultry industry without compromising animal welfare,which is a critical *** review focuses on important issues related to poultry product quality *** adulteration has escalated in recent years as it is driven by the increasing focus on consuming high-quality and nutritious ***,there is no specifc guideline for such determinations,especially when appearance,texture,and taste can be manipulated by substituting for food *** can pave the way for a deeper understanding of existing and novel biochemical indicators responsible for determining the quality of poultry meat and *** approach holds the potential to enhance the overall quality of poultry meat and egg products while also preventing food fraud.

关键词： Poultry metabolomics welfare application authentication.

Emerging bedaquiline resistance:A threat to the global fight against drug-resistant tuberculosis

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Journal of Biosafety and Biosecurity 2024年第1期6卷 13-15页

作者： Prakasini Satapathy Ramaiah Itumall Ahmad Neyazi Abdul Mobin Nabizai Taraki Mahalaqua Nazli khatib Shilpa Gaidhane Quazi Syed Zahiruddin Sarvesh Rustagi Mehrab Neyazi Center for Global Health Research Saveetha Medical College and HospitalSaveetha Institute of Medical and Technical SciencesSaveetha UniversityChennaiIndia Medical Laboratories Techniques Department AL-Mustaqbal University51001 HillahBabilIraq School of Management The Apollo UniversityChittoorAndhra Pradesh 517127India Afghanistan Center for Epidemiological Studies Afghanistan Division of Evidence Synthesis Global Consortium of Public Health and ResearchDatta Meghe Institute of Higher EducationWardhaIndia One Health Centre(COHERD) Jawaharlal Nehru Medical CollegeDatta Meghe Institute of Higher EducationWardhaIndia South Asia Infant Feeding Research Network(SAIFRN) Division of Evidence SynthesisGlobal Consortium of Public Health and ResearchDatta Meghe Institute of Higher EducationWardhaIndia School of Applied and Life Sciences Uttaranchal UniversityDehradunUttarakhandIndia

Bedaquiline resistance is increasingly observed in the treatment of rifampicin-resistant tuberculosis(TB),yet standardized regimens for managing bedaquiline-resistant TB are *** indicate a high proportion of bedaquiline-resistant cases have previously been treated for TB,and often involve strains resistant to *** monitoring of the culture status in patients receiving bedaquiline resistance treatment is *** such as experimental evolution,protein modeling,genome sequencing,and phenotypic analysis have been instrumental in identifying the mechanisms of bedaquiline ***,variants in the Rv0678 transcriptional repressor of the MmpS5-MmpL5 efflux system are linked to this type of *** probability estimates show promise in determining the genotypic–phenotypic association for bedaquiline resistance,suggesting potential utility in clinical *** research should explore the practical application of Bayesian probabilities in managing bedaquiline ***-based technologies are anticipated to play a vital role in the early detection and management of drug-resistant TB strains.

关键词： Bedaquiline Resistance Drug-Resistant Tuberculosis Quinolone Resistance

Impact of different intravenous bolus rates on fluid and electrolyte balance and mortality in critically ill patients

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World Journal of Critical Care Medicine 2024年第3期13卷 17-24页

作者： Mutaz I Othman Emad M Mustafa Moayad Alfayoumi Mohamad Y khatib Abdulqadir J Nashwan Department of Nursing Hamad Medical CorporationDoha 3050Qatar Department of Pharmacy Hamad Medical CorporationDoha 3050Qatar Department of Critical Care Hamad Medical CorporationDoha 3050Qatar

The effect of intravenous bolus rates on patient outcomes is a complex and crucial aspect of critical *** challenges are commonly used in critically ill patients to manage their hemodynamic status,but there is limited information available on the specifics of when,how much,and at what rate fluids should be administered during these *** aim of this review is to thoroughly examine the relationship between intravenous bolus rates,fluid-electrolyte balance,and mortality and to analyze key research findings and methodologies to understand these complex dynamics *** challenges are commonly employed in managing hemodynamic status in this population,yet there is limited information on the optimal timing,volume,and rate of fluid *** a narrative review approach,the analysis identified nine relevant studies that investigate these *** findings underscore the importance of a precise and individualized approach in clinical settings,highlighting the need to tailor intravenous bolus rates to each patient's specific needs to maximize *** review provides valuable insights that can inform and optimize clinical practices in critical care,emphasizing the necessity of meticulous and exact strategies in fluid administration.

关键词： Fluid balance Fluid resuscitation Intensive care unit Precision medicine Mortality

Ibuprofen-Induced Toxic Epidermal Necrolysis:A Case Report

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International Journal of Dermatology and Venereology 2024年第2期7卷 108-110页

作者： Nevin Kannappilly Mohamed Z.Peediyakkal Mohamad Y.khatib Dore C.Ananthegowda Moustafa S.elshafei Hani el Zeer Karimulla S.Shaik Moayad M.AlFayoumi Dyaneshwar P.Mutkule Ahmed A.Soliman Abdulqadir J.Nashwan Critical Care Department Hamad Medical Corporation(HMC)Doha 3050Qatar

Introduction:Toxic epidermal necrolysis(TEN)is a medical emergency that most commonly occurs as an adverse effect of certain ***,we describe a case of a 41-year-old man with no comorbid illness who developed *** presentation:The patient had been prescribed ibuprofen for myalgia and developed skin lesions after the single *** lesions were erythematous papules and macules distributed all over the body after ibuprofen *** was diagnosed based on the patient’s clinical presentation and laboratory *** was treated with intravenous dexamethasone,intravenous immunoglobulin,and *** dressing changes and skin care was done with saline,chlorhexidine,and liquid *** patient was intubated and tracheostomized,and he gradually improved and ***,he developed septicemia in the intensive care unit and was treated ***:The management of TEN includes cessation of the causative cause,multidisciplinary intensive care unit(ICU)care,prevention and early detection of sepsis,fluid and electrolyte balance,adequate analgesia and temperature control,proper organ support,aggressive nutritional management,and good psychological *** pharmacological therapy for TEN includes corticosteroids,intravenous immunoglobulin,and *** key elements of management are aseptic care and proper dressing of the ***:TEN is associated with high mortality if not managed in a systemic and protocolized way.

关键词： ibuprofen toxic epidermal necrolysis erythema drug-induced erythema

Disruption of biofilms from sewage pipes under physical and chemical conditioning

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Journal of Environmental Sciences 2009年第1期21卷 120-126页

作者： Charbel Mahfoud Antoine el Samrani Rita Mouawad Walid Hleihel Rim el khatib Bruno S. Lartiges Nam Ouani Holy Spirit University of Kaslik(USEK) Faculty of Sciences and Computer Engineering Department of Chemistry and Life SciencesWater and Environment Laboratory. P.B. 446JouniehLebanon Nancy University LEM-ENSG/INPL-CNRSPole de l'Eau15Avenue du CharmoisBP 40-F-54501 Vandoeuvre CedexFrance

Biofilms grown inside two sewage collecting pipes located in industrial and residential areas are studied. Bacterial biomass inside three layers of biofilms was evaluated. Biofilm cohesion under different mixing rate and ionic strength was also investigated. Effects of physical and chemical parameters in the biofilms were evaluated by monitoring turbidity, chemical and biochemical oxygen demands. Extracted organic matter from biofilms was partitioned to polar, aromatic and saturated fractions using activated silica column chromatography. Results revealed that bacterial biomass growth depending on biofilm thickness and stratification. The most loaded stratum in bacteria/biomass was the sewage-biofilm interface stratum that represented 51% of the total bacteria/biomass. Stirring rate and ionic strength of mono- and bivalent salts showed a major influence in biofilm disruption. The stirring time enhanced the exchange dynamic and matter capture between biofilm fragments at the critical stirring rate 90 r/min. Sodium chloride showed the dispersing effect on biofilms in suspension, and decreased the BOD5 （biochemical oxygen demand） beyond the physiological salt concentration.

关键词： biofilms, biochemical oxygen demand (BODs) chemical oxygen demand (COD) biomass ionic strength

Atomistic learning in the electronically grand-canonical ensemble

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npj Computational Materials 2023年第1期9卷 1619-1627页

作者： Xi Chen Muammar el khatib Per Lindgren Adam Willard Andrew J.Medford Andrew A.Peterson School of Engineering Brown UniversityProvidenceRI 02912USA Department of Chemistry Massachussetts Institute of TechnologyCambridgeMAUSA School of Chemical and Biomolecular Engineering Georgia Institute of TechnologyAtlantaGA 30318USA

A strategy is presented for the machine-learning emulation of electronic structure calculations carried out in the electronically grand-canonical *** approach relies upon a dual-learning scheme,where both the system charge and the system energy are predicted for each *** scheme is shown to be capable of emulating basic electrochemical reactions at a range of potentials,and coupling it with a bootstrap-ensemble approach gives reasonable estimates of the prediction *** method is also demonstrated to accelerate saddle-point searches,and to extrapolate to systems with one to five water *** anticipate that this method will allow for larger length-and time-scale simulations necessary for electrochemical simulations.

关键词： canonical ensemble electronic

An approach to evaluate the efficiency of γ-ray detectors to determine the radioactivity in environmental samples

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Chinese Physics C 2014年第6期38卷 60-66页

作者： Mohamed.S.Badawi Ahmed.M.el-khatib Samah.M.Diab Sherif.S.Nafee Ekram.A.el-Mallah Physics Department Faculty of Science Alexandria University 21511 Alexandria Egypt

This work provides an approach to determine the efficiency of T-ray detectors with a good accuracy in order to determine the concentrations of either naturally occurring or artificially prepared radionuclides. This approach is based on the efficiency transfer formula （ET）, the effective solid angles, the self- absorptions of the source matrix, the attenuation by the source container and the detector housing materials on the detector efficiency. The experimental calibration process was done using radioactive （Cylindrical ＆ Marinelli） sources, in different dimensions, that contain aqueous 152Eu radionuclide. The comparison point to a fine agreement between the experimental measured and calculated efficiencies for the （NaI ＆ HPGe） detectors using volumetric radioactive sources.

关键词： y-ray detector efficiency efficiency transfer effective solid angles radioactive source

Epidemiology,etiology,and outcomes of in-hospital cardiac arrest in Lebanon

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Journal of Geriatric Cardiology 2021年第6期18卷 416-425页

作者： Ahmed eltarras Youssef Jalloul Ola Assaad Michael Bejjani Yara Yammine Nina khatib Abdallah Rebeiz Mazen el Sayed Marwan Refaat Geriatric Medicine Division Saint Louis University School of MedicineMissouriUSA Department of Internal Medicine American University of Beirut Medical CenterBeirutLebanon Faculty of Medicine American University of BeirutBeirutLebanon School of Nursing American University of BeirutBeirutLebanon Department of Emergency Medicine American University of Beirut Medical CenterBeirutLebanon

BACKGROUND In-hospital cardiac arrest(IHCA)constitutes a significant cause of morbidity and *** data is scarce in the Middle East and Lebanon,we devised this study to shed some light on it to better inform both hospitals and policymakers about the magnitude and quality of IHCA care in *** We analyzed retrospective data from 680 IHCA events at the American University of Beirut Medical Center between July 1,2016 and May 2,*** variables included age and sex,in addition to the comorbidities listed in the Charlson comorbidity *** event variables were day,event location,time from activation to arrival,initial cardiac rhythm,and the total number of IHCA *** also looked at the months and *** considered the return of spontaneous circulation(ROSC)and survival to discharge(StD)to be our outcomes of *** The incidence of IHCA was 6.58 per 1,000 hospital admissions(95%CI:6.09−7.08).Non-shockable rhythms were 90.7%of *** IHCA cases occurred in the closed units(87.9%)(intensive care unit,respiratory care unit,neurology care unit,and cardiology care unit)and on weekdays(76.5%).ROSC followed more than half the IHCA events(56%).However,only 5.4%of IHCA events achieved *** ROSC and StD were higher in cases with a shockable *** outcomes were not significantly different between day,evening,and *** was not significantly different between weekdays and weekends;however,StD was higher in events that happened during weekdays than weekends(6.7%vs.1.9%,P=0.002).CONCLUSIONS The incidence of IHCA was high,and its outcomes were lower compared to other developed *** outcomes were better for patients who had a shockable rhythm and were similar between the time of day and days of the *** findings may help inform hospitals and policymakers about the magnitude and quality of IHCA care in Lebanon.

关键词： policy return listed

The role of nickel(II) on the homochirality of amino acids in living systems

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Chinese Chemical Letters 2010年第1期21卷 113-116页

作者： Awni khatib Fathi Aqra Department of Chemistry Faculty of Science and TechnologyHebron UniversityPO Box 40HebronWest BankPalestine

The origin of homochirality in living organisms is controversial,stands out of being particularly important and a question which is still not satisfactorily answered.A mental picture of sequence of events that is thought to have preceded the existence of chirality in molecules is described.A chemical model to mimic the original abiotic conditions in an attempt to explain the preference of homochirality in living systems was *** effect which might have influenced this preference is *** surpri...

关键词： Homochirality Living organisms Chiral preference