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Neural Regeneration Research 2012年第36期7卷 2929-2936页

作者： osman zdel Demet Kalayci Gülfizar Szeri-Varma Yilmaz Kiroglu Selim Tümkaya Tuge Toker-Ugurlu Department of Psychiatry Faculty of MedicinePamukkale University Department of Psychiatry Antalya Training and Research Hospital Department of Radiology Faculty of MedicinePamukkale University

The aim of this study was to investigate proton magnetic resonance spectroscopy metabolite values in the medial prefrontal cortex of individuals with euthymic bipolar disorder. The subjects consisted of 15 patients with euthymic bipolar disorder type I and 15 healthy controls. We performed proton magnetic resonance spectroscopy of the bilateral medial prefrontal cortex and measured levels of N-acetyl aspartate, choline and creatine. Levels of these three metabolites in the medial prefrontal cortex were found to be lower in patients with bipolar disorder compared with healthy controls. A positive correlation was found between illness duration and choline levels in the right medial prefrontal cortex. Our study suggests that during the euthymic period, there are abnormalities in cellular energy and membrane phospholipid metabolism in the medial prefrontal cortex, and that this may impair neuronal activity and integrity.

关键词： bipolar disorder proton magnetic resonance spectroscopy medial prefrontal cortex N-asetylaspartate choline creatine degradation mood disorder neurochemical metabolite illness duration neural regeneration

Evidence supporting the relationship between maternal asthma and risk for autism spectrum disorders

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Neural Regeneration Research 2025年第4期20卷 1101-1102页

作者： Hadley osman Paul Ashwood Department of Medical Microbiology and Immunology and the M.I.N.D.InstituteUniversity of California at DavisSacramentoCAUSA

During pregnancy,maternal immune activation(MIA),due to infection,chronic inflammatory disorders,or toxic exposures,can result in lasting health impacts on the developing *** has been associated with an increased risk of neurodevelopmental disorders,such as autism spectrum disorder(ASD)in the *** is characterized by increased repetitive and stereotyped behaviors and decreased *** of 2020,1 in 36 children are diagnosed with ASD by the age of 8 years,with ASD rates continuing to increase in prevalence in USA(Tamayo et al.,2023).Post-mortem brain studies,biomarker and transcriptomic studies,and epidemiology studies have provided compelling evidence of immune dysregulation in the circulation and brain of individuals diagnosed with ***,the etiology of ASD is largely unknown,however,genetic components and environmental factors can contribute to increased *** allergic asthma(MAA),a form of MIA,has been identified as a potential risk factor for developing neurodevelopmental disorders(Patel et al.,2020).Asthma is a chronic inflammatory condition driven by a T-helper type(TH)2 immune response.

关键词： disorders epidemiology fetus

Indentation Load Effect on Young＇s Modulus and Hardness of Porous Sialon Ceramic by Depth Sensing Indentation Tests

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Chinese Physics Letters 2007年第11期24卷 3206-3209页

作者： osman SAHIN Department of Physics Art and Science Faculty Silleyman Demirel University Isparta Turkey

Depth sensing indentation （DSI） tests at the range of 200-1800mN are performed on porous sialon ceramic to determine the indentation load on Young＇s modulus and hardness values. The Young modulus and hardness （Dynamic and Martens） values are deduced by analysing the unloading segments of the DSI test load-displacement curves using the Oliver-Pharr method. It is found that Young＇s modulus ET, the dynamic hardness HD and the Martens hardness HM exhibit significant indentation load dependences. The values of Young＇s modulus and hardness decrease with the increasing indentation load, as a result of indentation load effect. The experimental hf /hm ratios lower than the critical value 0.7, with hm being the maximum penetration depth during loading and hf the final unloading depth, indicate that our sample shows the work hardening behaviour.

关键词： coated conductor buffer layer self-epitaxy CeO2

The Tauride Ophiolites of Anatolia(Turkey):A Review

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Journal of Earth Science 2016年第6期27卷 901-934页

作者： osman Parlak Cukurova On Universitesi Jeoloji Muhendisligi Bolumu Balcah Adana 01380 Turkey

The Tauride ophiolites lie on the northern and southern flanks of an E-W-trending Tanride carbonate platform. They mainly consist of three tectonic units namely in ascending order, ophiolitic melange, sub-ophiolitic metamorphic sole and oceanic lithospheric remnants. They were generated above intra-oceanic subduction zones and emplaced over the Tauride carbonate platform from different Neotethyan oceanic basins in the Late Cretaceous. Tauride ophiolites from west to east are described and reviewed. All are underlain by well-preserved dynamothermal metamorphic soles of varied structural thicknesses up to 500 m that have a constant structural position between ophiolitic melange below and harzburgitic mantle tectonites above and display typical inverted metamorphic sequences from amphibolite facies above to greenschist facies below. The metamorphic soles are shown to have evolved during the initiation of subduction and emplacement processes. In the PozantlKarsantl area the contact between the metamorphic sole and the overlying serpentinized harzburgites is characterized by a 1.5-2-m-thick zone of sheared serpentinized harzburgitic mantle intercalated with amphibolites and cut by thick mafic dykes （7-8 m） which postdate intraoceanic metamorphism and high-temperature ductile deformation. This contact is interpreted as an intra-oceanic decoupling surface along which volcanics from the upper levels of the down-going plate were metamorphosed to amphibolite facies and accreted to the base of the hanging wall plate. The metamorphic soles and overlying ophiolitic rocks were intruded by numerous isolated post-metamorphic diabase dykes filled by island arc tholeiitic magma. Subduction initiation and roll-back processes best explain the structural and petrological relationships of Late Cretaceous ophiolite genesis, metamorphic sole formation and subsequent dyke emplacement of the Tauride ophiolites.

关键词： ophiolite metamorphic sole dyke emplacement roll-back subduction initiation.

Relaxation theory of spin-3/2 Ising system near phase transition temperatures

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Chinese Physics B 2010年第8期19卷 257-269页

作者： osman Canko Mustafa Keskin Department of Physics Erciyes University

Dynamics of a spin-3/2 Ising system Hamiltonian with bilinear and biquadratic nearest-neighbour exchange interactions is studied by a simple method in which the statistical equilibrium theory is combined with the Onsager＇s theory of irreversible thermodynamics. First, the equilibrium behaviour of the model in the molecular-field approximation is given briefly in order to obtain the phase transition temperatures, i.e. the first- and second-order and the tricritical points. Then, the Onsager theory is applied to the model and the kinetic or rate equations are obtained. By solving these equations three relaxation times are calculated and their behaviours are examined for temperatures near the phase transition points. Moreover, the z dynamic critical exponent is calculated and compared with the z values obtained for different systems experimentally and theoretically, and they are found to be in good agrement.

关键词： spin-3/2 Ising system 0nsager theory

Chromium Substitution Effect on the Magnetic Structure of Iron Oxides

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Chinese Physics Letters 2012年第5期29卷 217-220页

作者： osman Murat Ozkendir Mersin University Tarsus Technical Faculty of EducationTarsusTurkey UVSOR FacilityInstitute for Molecular ScienceOkazaki 444-8585Japan

The local magnetic and electronic structures of chromium substituted iron oxide polycrystalline samples are investigated via Fe L-edge x-ray absorption near-edge structural and magnetic circular dichroism measurements.A strong dependence of atomic magnetic levels on the applied external magnetic field is *** magnetic behavior of Cr-doped iron oxides are determined to be dominantly governed by the d-d hybridization between Fe and Cr valence *** addition,the formation of CrO_(2) and Cr_(2)O_(3) chromium oxide clusters in the sample are observed to determine the magnetic ordering,***-ferromagnetic or ferromagnetic with the changing external magnetic *** results highly agree with the previous studies.

关键词： chromium ferromagnetic magnetic

Frenet Curve Couples in Three Dimensional Lie Groups

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Computer Modeling in Engineering & Sciences 2022年第12期133卷 653-671页

作者： osman Zeki Okuyucu Department of Mathematics Faculty of Science and ArtsBilecik Seyh Edebali UniversityBilecikTurkey

In this study,we examine the possible relations between the Frenet planes of any given two curves in three dimensional Lie groups with left invariant *** explain these possible relations in nine cases and then introdu... 详细信息

关键词： Curves lie groups curvatures Frenet plane

Coronavirus Detection Using Two Step-AS Clustering and Ensemble Neural Network Model

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Computers, Materials & Continua 2022年第6期71卷 6307-6331页

作者： Ahmed Hamza osman Department of Information System Faculty of Computing and Information Technology King Abdulaziz University RabighSaudi Arabia

This study presents a model of computer-aided intelligence capable of automatically detecting positive COVID-19 instances for use in regular medical *** proposed model is based on an Ensemble boosting Neural Network architecture and can automatically detect discriminatory features on chestX-ray images through Two Step-As clustering algorithm with rich filter families,abstraction and weight-sharing *** contrast to the generally used transformational learning approach,the proposed model was trained before and after *** compilation procedure divides the datasets samples and categories into numerous sub-samples and subcategories and then assigns new group labels to each new group,with each subject group displayed as a distinct *** retrieved characteristics discriminant cases were used to feed the Multiple Neural Network method,which was then utilised to classify the *** Two Step-AS clustering method has been modified by pre-aggregating the dataset before applying Multiple Neural Network algorithm to detect COVID-19 cases from chest X-ray *** forMultiple Neural Network and Two Step-As clustering algorithms were optimised by utilising Ensemble Bootstrap Aggregating algorithm to reduce the number of hyper parameters they *** testswere carried out using theCOVID-19 public radiology database,and a cross-validationmethod ensured *** proposed classifier with an accuracy of 98.02%percent was found to provide the most efficient outcomes *** result is a lowcost,quick and reliable intelligence tool for detecting COVID-19 infection.

关键词： Two step-AS clustering ensemble learning bootstrap aggregating multiple neural network covid-19 X-ray images

Liver transplantation: Yesterday, today and tomorrow

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World Journal of Gastroenterology 2008年第20期14卷 3117-3122页

作者： osman Abbasoglu Department of Surgery Hacettepe University School of Medicine

With the advances in technical skills, management of postoperative complications and improvements in immunosuppressive drugs, liver transplantation is the standard treatment for many patients with chronic liver disease. Today, shortage of donor organs seems to be the major limiting factor for the application of liver transplantation. This review focuses on five issues that are challenging to clinical practice of liver transplantation and relevant to gastroenterologists. These include living donor liver transplantation, recurrent viral hepatitis, non-heart-beating donors, hepatocellular carcinoma, and ABO incompatible liver transplantation. Living donor and non-heart beating donor transplantations were initiated as a solution to increase the donor organ pool and it is expected that there will be an increase in the number of these donors. Recurrent hepatitis C and hepatocellular carcinoma following liver transplantation are among major problems and ongoing research in these diseases may lead to better outcomes in these recipients.

关键词： Liver transplantation Hepatitis C virus Hepatitis B virus Hepatocellular carcinoma ABOincompatibility Living donor

Formally Analyzing Expected Time Complexity of Algorithms Using Theorem Proving

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Journal of Computer Science & Technology 2010年第6期25卷 1305-1320页

作者： osman Hasan Sofiène Tahar Department of Electrical and Computer Engineering Concordia University

Probabilistic techniques are widely used in the analysis of algorithms to estimate the computational complexity of algorithms or a computational ***,such analyses are performed using paper-and-pencil proofs and the results are sometimes validated using simulation *** techniques are informal and thus may result in an inaccurate *** this paper,we propose a formal technique for analyzing the expected time complexity of algorithms using higher-order-logic theorem *** approach calls for mathematically modeling the algorithm along with its inputs,using indicator random variables,in higher-order *** model is then used to formally reason about the expected time complexity of the underlying algorithm in a theorem *** paper includes the higher-order-logic formalization of indicator random variables,which are fundamental to the proposed *** order to illustrate the practical effiectiveness and utilization of the proposed infrastructure,the paper also includes the analysis of algorithms for three well-known problems,i.e.,the hat-check problem,the birthday paradox and the hiring problem.

关键词： formal method higher-order logic probability theory theorem proving birthday paradox hat-check problem hiring problem