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心脏舒张功能障碍逆转的临床探讨

心血管康复医学杂志 2012年第2期21卷 162-164页

作者：王瑛崔玉娟陈玉丽王照谦坂本真吾永井阳子杨国慧朴鑫李峰春朱丽丽张新颖张哿马临庆王超易威林阳大连维特奥国际医院辽宁大连116001 长春市中心医院大连医科大学附属第一医院

目的:探讨心脏舒张功能障碍的逆转。方法:入选我院舒张功能障碍的病人223例,随机分为常规治疗组,给予丹参滴注液16g,1次/d;磷酸肌酸钠组:在常规治疗组基础上给予磷酸肌酸钠静脉滴注(轻度舒张功能障碍每日给药2.0g,中重度舒张功能障碍给... 详细信息

目的:探讨心脏舒张功能障碍的逆转。方法:入选我院舒张功能障碍的病人223例,随机分为常规治疗组,给予丹参滴注液16g,1次/d;磷酸肌酸钠组:在常规治疗组基础上给予磷酸肌酸钠静脉滴注(轻度舒张功能障碍每日给药2.0g,中重度舒张功能障碍给药2.0g,2次/d),并采用彩色多普勒超声心动图观察二尖瓣口舒张早期峰值流速(E)、二尖瓣口舒张晚期峰值流速(A)、二尖瓣环舒张早期速度峰值(Ea)、二尖瓣环舒张晚期速度峰值(Aa),计算E/A值,Ea/Aa值,E/Ea值。连续治疗14d,并根据治疗前后临床症状、体征及彩色多普勒超声心动图各指标改善情况评价疗效。结果:治疗后,与常规治疗组比较,磷酸肌酸钠组患者的症状、体征显效率(53.8%比98.2%,62.5%比92.0%),综合疗效的显效率(11.43%比82.97%),E/A值[(0.82±0.15)比(1.20±0.24)]、Ea/Aa值[(0.88±0.23)比(1.56±0.31)]显著提高,E/Ea值[(9.89±3.15)比(5.84±2.12)]显著降低,P均<0.01。结论:舒张功能障碍早期发现和干预是可以逆转的,磷酸肌酸钠有显著的治疗作用,是逆转舒张功能障碍的首选药物。

关键词：心室功能障碍磷酸肌酸丹参注射液

不同海拔高度藏汉族老年人血压变化的特点及影响因素

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高原医学杂志 2011年第4期21卷 14-18页

作者：代青湘李占全王红心许慧宁高继东杨爱荣仝海英奥宫清人松林公藏坂本龙泰木村友美张永寿王建萍才仁松保尼玛乔海生青海大学附属医院 810001 日本综合环境地球研究所青海省海北州海晏县人民医院 812200 青海省玉树州玉树县人民医院 815000 青海省畜牧兽医科学院 810016

目的:通过对不同海拔地区藏汉族老年人进行健康调查,进一步了解高原地区老年人血压变化的特点及影响因素。方法:采用随机抽样的方法,对青海省玉树县(平均海拔3 700m)、海晏县(平均海拔3 000m以上)两地区506例60岁～87岁世居藏族及移居... 详细信息

目的:通过对不同海拔地区藏汉族老年人进行健康调查,进一步了解高原地区老年人血压变化的特点及影响因素。方法:采用随机抽样的方法,对青海省玉树县(平均海拔3 700m)、海晏县(平均海拔3 000m以上)两地区506例60岁～87岁世居藏族及移居汉族的血压进行健康调查。结果:①玉树县老年人高血压的患病率显著高于海晏县,收缩压(SBP)、舒张压(DBP)及体质指数(BMI)显著高于海晏县老年人,P<0.05;玉树县藏族老年人高血压的患病率显著高于海晏县藏族,同时SBP、DBP及BMI均显著高于海晏县藏族,均P<0.05;②海晏县汉族老年人高血压的患病率显著高于海晏县藏族,同时汉族SBP、DBP均显著高于藏族,均P<0.05;③高原地区老年人高血压患病率为50.6%,男、女患病率无明显差异;高血压组的BMI、脉率(HR)及血红蛋白(Hb)显著高于血压正常组,血氧饱和度(SpO2)低于血压正常组,P<0.05。结论:高原地区老年人高血压的患病率高于海拔较低的地区,汉族高血压的患病率高于藏族;高原低氧、低温环境是高原地区老年人血压增高的重要影响因素,移居汉族、超重及牧区镇城居民更易患高血压病。

关键词：高原老年人藏族血压低氧环境

九价人乳头瘤病毒疫苗的保护效力、免疫原性和安全性:亚洲人群亚组分析

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中国病毒病杂志 2018年第4期8卷 336-342页

作者： S.M.Garland P.Pitisuttithum H.Y.S.Ngan C.-H.Cho C.-Y.Lee C.-A.Chen Y.C.Yang T.-Y.Chu N.-F.Twu R.Samakoses Y.Takeuchi T.H.Cheung S.C.Kim L.-M.Huang B.-G.Kim Y.-T.Kim K.-H.Kim Y.-S.Song S.Lalwani J.-H.Kang M.sakamoto H.-S.Ryu N.Bhatla H.Yoshikawa M.C.Ellison S.R.Han E.Moeller S.Murata M.Ritter M.Sawata C.Shields A.Walia G.Perez A.Luxembourg 魏丽惠北京大学人民医院妇产科不详

预防性人乳头瘤病毒（HPV）疫苗接种可以降低HPV相关疾病负担。过去十年内上市的二价HPV疫苗（HPV16、18）和四价疫苗（HPV6、11、16、18）可以在全世界范围内（包括亚州）预防约70%的宫颈癌,同时四价疫苗还可以预防约90%的生殖器疣。

关键词：九价HPV疫苗亚洲宫颈癌人乳头瘤病毒疫苗

Observatory science with eXTP

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Science China(Physics,Mechanics & Astronomy) 2019年第2期62卷 97-138页

作者： Jean J.M.in 't Zand Enrico Bozzo JinLu Qu Xiang-Dong Li Lorenzo Amati Yang Chen Immacolata Donnarumma Victor Doroshenko Stephen A.Drake Margarita Hernanz Peter A.Jenke Thomas J.Maccarone Simin Mahmoodifar Domitilla de Martino Alessandra De Rosa Elena M.Rossi Antonia Rowlinson Gloria Sala Giulia Stratta Thomas M.Tauris Joern Wilms XueFeng Wu Ping Zhou Iván Agudo Diego Altamirano Jean-Luc Atteia Nils A.andersson M.Cristina Baglio David R.Ballantyne Altan Baykal Ehud Behar Tomaso Belloni Sudip Bhattacharyya Stefano Bianchi Anna Bilous Pere Blay Joao Braga Sφren Brandt Edward F.Brown Niccolo Bucciantini Luciano Burderi Edward M.Cackett Riccardo Campana Sergio Campana Piergiorgio Casella Yuri Cavecchi Frank Chambers Liang Chen Yu-Peng Chen Jér?me Chenevez Maria Chernyakova ChiChuan Jin Riccardo Ciolfi Elisa Costantini Andrew Cumming Antonino D'Aì Zi-Gao Dai Filippo D'Ammando Massimiliano De Pasquale Nathalie Degenaar Melania Del Santo Valerio D'Elia Tiziana Di Salvo Gerry Doyle Maurizio Falanga XiLong Fan Robert D.Ferdman Marco Feroci Federico Fraschetti Duncan K.Galloway Angelo F.Gambino Poshak Gandhi MingYu Ge Bruce Gendre Ramandeep Gill Diego G?tz Christian Gouiffès Paola Grandi Jonathan Granot Manuel Güdel Alexander Heger Craig O.Heinke Jeroen Homan Rosario Iaria Kazushi Iwasawa Luca Izzo Long Ji Peter G.Jonker Jordi José Jelle S.Kaastra Emrah Kalemci Oleg Kargaltsev Nobuyuki Kawai Laurens Keek Stefanie Komossa Ingo Kreykenbohm Lucien Kuiper Devaky Kunneriath Gang Li En-Wei Liang Manuel Linares Francesco Longo FangJun Lu Alexander A.Lutovinov Denys Malyshev Julien Malzac Antonios Manousakis Ian McHardy Missagh Mehdipour YunPeng Men Mariano Méndez Roberto P.Mignani Romana Mikusincova M.Coleman Miller Giovanni Miniutti Christian Motch Joonas Nättilä Emanuele Nardini Torsten Neubert Paul T.O'Brien Mauro Orlandini Julian P.Osborne Luigi Pacciani Stéphane Paltani Maurizio Paolillo Iossif E.Papadakis Biswajit Paul Alberto Pellizzoni Uria Peretz Miguel A.Pérez Torres Emanuele Perinati Chanda Prescod-Weinstein Pablo Reig SRON Netherlands Institute for Space Research Department of Astronomy University of Geneva Key Laboratory for Particle Astrophysics Institute of High Energy PhysicsChinese Academy of Sciences School of Astronomy and Space Science Nanjing University INAF-IASF Bologna ASI Via del Politecnico snc INAF-Istituto di Astrofisica e Planetologie Spaziali Institut für Astronomie und Astrophysik Tübingen Universit?t Tübingen NASA Goddard Space Flight Center ICREA&Institute of Space Sciences(IEEC-CSIC) Campus UABCarrer de Can Magrans CSPAR SPA University of Alabama in Huntsville Department of Physics Texas Tech University INAF Osservatorio Astronomico di Capodimonte Leiden Observatory Leiden University Anton Pannekoek Institute University of Amsterdam ASTRON Netherlands Institute for Radio Astronomy Universitat Politecnica de Catalunya(UPC-IEEC) Universitádegli Studi di Urbino‘Carlo Bo’ Max-Planck-Institut für Radioastronomie Dr.Karl-Remeis-Sternwarte and Erlangen Centre for Astroparticle Physics(ECAP) Friedrich Alexander Universit?t Erlangen-Nurnberg Purple Mountain Observatory Chinese Academy of Sciences Instituto de Astrofysíca de Andalucia-CSIC Department of Physics and Astronomy University of Southampton IRAP Universitéde ToulouseCNRSUPSCNES Mathematical Sciences and STAG Research Centre University of Southampton New York University Abu Dhabi Center for Relativistic Astrophysics School of PhysicsGeorgia Institute of Technology Physics Department Middle East Technical University Department of Physics Technion-Israel Institute of Technology INAF Osservatorio Astronomico di Brera Tata Institute of Fundamental Research Dipartimento di Matematica e Fisica Universitàdegli Studi Roma Tre Instituto de Astrofísica de Canarias Instituto Nacional de Pesquisas Espaciais-INPE National Space Institute Technical University of Denmark(DTU Space) Department of Physics and Astronomy Michigan State University INAF Osservatorio Astrofisico di Arcetri Dipartimento di Fisica Universitádegli Studi di Cagliari Department of Physics and A

In this White Paper we present the potential of the enhanced X-ray Timing and Polarimetry(eXTP) mission for studies related to Observatory Science targets. These include flaring stars, supernova remnants, accreting white dwarfs, low and high mass X-ray binaries, radio quiet and radio loud active galactic nuclei, tidal disruption events, and gamma-ray bursts. eXTP will be excellently suited to study one common aspect of these objects: their often transient nature. Developed by an international Consortium led by the Institute of High Energy Physics of the Chinese Academy of Science, the eXTP mission is expected to be launched in the mid 2020s.

关键词： space research in struments nuclear astrophysics flare stars accretion and accretion disks mass loss and stellar winds cataclysmic binaries X-ray binaries supernova remnants active galactic nuclei X-ray bursts gamma-ray bursts gravitational waves