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Hydrogen gas and preservation of intestinal stem cells in mesenteric ischemia and reperfusion

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World Journal of Gastrointestinal Surgery 2022年第12期14卷 1329-1339页

作者： Ryo Yamamoto Sayuri Suzuki Koichiro homma Shintaro Yamaguchi Tomohisa Sujino Junichi Sasaki Department of Emergency and Critical Care Medicine Keio University School of MedicineTokyo 1608582Japan Division of Endocrinology Metabolism and NephrologyDepartment of Internal MedicineKeio University School of MedicineTokyo 1608582Japan Division of Gastroenterology and Hepatology Department of Internal MedicineKeio University School of MedicineTokyo 1608582Japan

BACKGROUND Patients with mesenteric ischemia frequently suffer from bowel necrosis even after *** gas has showed promising effects for ischemiareperfusion injury by reducing reactive oxygen species in various animal and clinical *** examined intestinal tissue injury by ischemia and reperfusion under continuous initiation of 3%hydrogen *** To clarify the treatment effects and target cells of hydrogen gas for mesenteric *** Three rat groups underwent 60-min mesenteric artery occlusion(ischemia),60-min reperfusion following 60-min occlusion(reperfusion),or ischemiareperfusion with the same duration under continuous 3%hydrogen gas inhalation(hydrogen).The distal ileum was *** staining with caspase-3 and leucine-rich repeat-containing G-protein-coupled 5(LGR5),a specific marker of intestinal stem cell,was conducted to evaluate the injury location and cell types protected by *** expressions of LGR5,olfactomedin 4(OLFM4),hairy and enhancer of split 1,Jagged 2,and Neurogenic locus notch homolog protein 1 were measured by quantitative polymerase chain *** oxidative stress was analyzed with immunostaining for 8-hydroxy-2'-deoxyguanosine(8-OHdG).Systemic oxidative stress was evaluated by plasma *** Ischemia damaged the epithelial layer at the tip of the villi,whereas reperfusion induced extensive apoptosis of the cells at the crypt base,which were identified as intestinal stem cells with double immunofluorescence *** mitigated such apoptosis at the crypt base,and the LGR5 expression of the tissues was higher in the hydrogen group than in the reperfusion ***4 was also relatively higher in the hydrogen group,whereas other measured RNAs were comparable between the groups.8-OHdG concentration was high in the reperfusion group,which was reduced by hydrogen,particularly at the crypt *** 8-OHdG concentrations were relatively higher in both reperfusion and

关键词： Hydrogen molecule Intestinal ischemia Ischemia-reperfusion injury Tissue protection Nonoperative management Leucine-rich repeat-containing G-protein-coupled 5

Effects of erect panicle genotype and environment interactions on rice yield and yield components

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Journal of Integrative Agriculture 2023年第3期22卷 716-726页

作者： WANG Yuan-zheng Olusegun IDOWU WANG Yun homma Koki NAKAZAKI Tetsuya ZHENG Wen-jing XU Zheng-jin SHIRAIWA Tatsuhiko Rice Research Institute Liaoning Academy of Agricultural SciencesShenyang 110101P.R.China Division of Agronomy and Horticulture Science Graduate School of AgricultureKyoto UniversityKyoto 606-8501Japan Rice Research Institute Shenyang Agricultural University/Key Laboratory of Northeast Rice Biology and BreedingMinistry of Agriculture and Rural Affairs/Key Laboratory of Northern Japonica Super Rice BreedingMinistry of EducationShenyang 110866P.R.China Division of Biological Resource Sciences Graduate School of Agricultural ScienceTohoku UniversitySendai 980-8576Japan

The dense and erect panicle (EP) genotype conferred by DEP1 has been widely used in the breeding of high-yield Chinese japonica rice ***,the breeding value of the EP genotype has rarely been determined at the plant population ***,the effects of the interaction of EP genotype and the environment at different locations and times on rice yield and its various components were investigated in this *** sets of near-isogenic lines (NILs)of EP and non-EP (NEP) genotypes with Liaojing 5 (LG5) and Akitakomachi (AKI) backgrounds were grown in the field in 2016 and 2017 in Shenyang,China,and Kyoto,*** 2018,these sets were grown only in Kyoto,*** average yields of the EP and NEP genotypes were 6.67 and 6.13 t ha^(-1)for the AKI background,and 6.66 and 6.58 t ha^(-1)for the LG5 background,*** EP genotype positively affected panicle number (PN) and grain number per square meter (GNPM),mostly resulting in a positive effect on harvest index (HI).In contrast,the EP genotype exerted a negative effect on thousand-grain weight (KGW).The ratio of the performance of the EP genotype relative to the NEP genotype in terms of yield and total biomass correlated positively with mean daily solar radiation during a 40-day period around *** results indicate that the effectiveness of the EP genotype depends on the availability of solar radiation,and the effect of this genotype is consistently positive for sink formation,conditional in terms of source capacity,and positive in a high-radiation environment.

关键词： erect panicle genotype by environment interaction rice(Oryza sativa L.) solar radiation yield

Single-Walled Carbon Nanotube Growth with Non-Iron- Group “Catalysts” by Chemical Vapor Deposition

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Nano Research 2009年第10期2卷 793-799页

作者： Yoshikazu homma Huaping Liu Daisuke Takagi Yoshihiro Kobayashi Department of Physics Tokyo University of ScienceShinjukuTokyo 162-8601Japan NTT Basic Research Laboratories Nippon Telegraph and Telephone CorporationAtsugiKanagawa 243-0198Japan National Institute of Advanced Industrial Science and Technology Nanotechnology Research InstituteTsukubaIbaraki305-8561Japan Department of Applied Physics Osaka UniversitySuitaOsaka 565-0871Japan

Various materials have been found to“catalyze”carbon nanotube growth in chemical vapor deposition(CVD)when they become nano-sized *** involve not only metals,such as Pd,Pt,Au,Ag,and Cu,but also semiconductors,such as Si,Ge,and *** and diamond nanoparticles also produce carbon ***“catalysts”,which are better called“seeds”,can be categorized into two types:one type forms a eutectic liquid or highly-mobile alloy with carbon,and carbon atoms precipitate from the eutectic alloy;the other type remains as a solid phase and form a carbon surface layer during CVD *** this paper,we review recent studies of SWCNT growth with these non-iron-group materials and highlight the mechanisms involved.

关键词： Carbon nanotube catalyst seed growth mechanism chemical vapor deposition vapor liquid solid mechanism

Transcatheter arterial embolization for traumatic injury to the pharyngeal branch of the ascending pharyngeal artery:Two case reports

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World Journal of Clinical Cases 2022年第32期10卷 12015-12021页

作者： Daisuke Yunaiyama Yuki Takara Takehiro Kobayashi Mika Muraki Taro Tanaka Mitsuru Okubo Toru Saguchi Motoki Nakai Kazuhiro Saito Kiyoaki Tsukahara Yuri Ishii Hiroshi homma Department of Radiology Tokyo Medical University HospitalShinjuku-ku 160-0023Japan Department of Otorhinolaryngology Head and Neck SurgeryTokyo Medical University HospitalShinjuku-ku 160-0023Japan Department of Emergency and Critical Care Medicine Tokyo Medical University HospitalShinjuku-ku 160-0023Japan

BACKGROUND The ascending pharyngeal artery(APhA)comprises the pharyngeal trunk(PT)and neuromeningeal *** PT feeds the nasopharynx and adjacent tissue,which potentially connects with the sphenopalatine artery(SPA),branched from the internal maxillary artery(IMA).Due to its location deep inside the body,the PT is rarely injured by ***,we present two cases that underwent transcatheter arterial embolization(TAE)of the PT of the APhA due to trauma and iatrogenic *** SUMMARY Case 1 is a 49-year-old Japanese woman who underwent transoral endoscopy under sedation for a medical *** nasal airway was inserted as glossoptosis occurred during *** from the nasopharynx was observed during the endoscopic *** the bleeding continued,the patient was referred to our hospital for further ***-enhanced computed tomography(CT)demonstrated extravasation in the nasopharynx originating from the right Rosenmuller *** was performed and the extravasation disappeared after *** 2 is a 28-year-old Japanese woman who fell from the sixth floor of a building and was transported to our *** CT demonstrated a complex facial fracture accompanying extravasation in the left pterygopalatine fossa to the *** demonstrated an irregular third portion of the *** angiography after TAE of the IMA demonstrated extravasation from the PT of the APhA,additional TAE to the artery was *** bleeding stopped after the *** Radiologists should be aware that the PT of the APhA can be a bleeding source,which has a potential connection with the SPA.

关键词： Arteries Catheters Hemorrhage Injury Trauma Case report

A Newly Developed Non-Destructive Tritium Measurement Technique and Its Application to V-4Cr-4Ti Alloy

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Plasma Science and Technology 2006年第6期8卷 741-744页

作者：刘翔陈学 H.homma Y.HATANO M.MATSUYAMA Southwestern Institute of Physics Chengdu 610041China Sichuan General Fire Brigade Chengdu 610072China Hydrogen Isotope Research Centre Toyama UniversityGofuku 3190Toyama 930-8555Japan

A non-destructive and in-situ technique for the measurement of tritium in materials, namely β-ray-induced X-ray spectrometry （BIXS）, has been developed recently. In the present study a V-4Cr-4Ti alloy was pre-heated at 1000℃ for 2 h to form a recrystallization structure before the tritium absorption experiments were conducted. Firstly the hydrogen isotope gas was charazterized by means of a quadrupole mass spectrometer （QMS） and a small-sized ionization chamber. Then hydrogen isotope absorption tests of V-4Cr-4Ti alloy were performed at 400 ℃ and the atomic concentration of hydrogen isotope in V-4Cr-4Ti alloy was estimated as 0.17% with a tritium content of approximately 2.5 ppm. Experimental results indicate that BIXS is a quite useful tool for quantitatively measuring the tritium content and tritium distribution in the surface layers of vanadium alloys and no strong trapping effects of tritium exist in the pre-heated V-4Cr-4Ti alloy.

关键词： tritium V-4Cr-4Ti β-ray-induced X-ray spectrometry tritium measurements

Are we leveling the playing field？ Trends and disparities in sports participation among sexual minority youth in Canada

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Journal of Sport and Health Science 2018年第2期7卷 218-226页

作者： Marion Doull Ryan J.Watson Annie Smith Yuko homma Elizabeth Saewyc Stigma and Resilience Among Vulnerable Youth Centre School of Nursing University of British Columbia Vancouver British Columbia V6T2B5 Canada Department of Human Development and Family Studies University of Connecticut Storrs CT 06269 USA McCreary Centre Society Vancouver British Columbia V5K2A 7 Canada School of Nursing Mukogawa Women's University Nishinomiya Hyogo 663-8558 Japan

Purpose: Sports participation and physical fitness are widely beneficial for young people, yet activity levels among young people are *** growing popular media attention on the participation of sexual minority(e.g., lesbian, gay, and bisexual) youth in sports and various campaigns to improve the often homophobic climate of sports, there is limited evidence that sexual minority youth participate in sports. Our aim was to provide a current portrait of sports participation among 3 groups of sexual minority youth(e.g., lesbian, gay, and bisexual) in British Columbia, Canada, as well as to document population ***: Pooled population-level data from British Columbia, Canada(n = 99,373) were used to examine trends and disparities in sports participation among sexual minority and heterosexual youth. Age-adjusted logistic regression models were used to examine changes in participation over time and disparities in participation over time(1998—2013).Results: We found an overall decline in sports participation and physical activity(PA) for all youth. Sexual minority students were less likely to participate in formal sports(with a coach) and informal sports(without a coach) compared with their heterosexual peers. The disparity in participating in informal sports between heterosexual and sexual minority youth has narrowed over time for some sexual orientation groups, whereas the disparity in participating in formal sports has widened over time in some ***: This study provides a comprehensive examination of sports participation among sexual minority youth over the past 15 *** changing societal attitudes and laudable efforts to reduce homophobia in sports, results suggest that there are continued barriers to participation for sexual minority youth. Further research is needed to understand the factors that limit sports participation for these youth and to inform program development. PA is critical to lifelong health and well-being, and

关键词：运动场加拿大青春不列颠哥伦比亚逻辑回归模型同性恋社会态度程序开发

Numerical Analysis on Wood Pyrolysis in Pre-Vacuum Chamber

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Journal of Sustainable Bioenergy Systems 2014年第3期4卷 149-160页

作者： Hiroki homma Hiroomi homma Muhammad Idris National Institute of Technology Matsue College Nishiikumacho Matsue Japan University of North Sumatera Jl. Almamater Medan Indonesia

In the previous experimental work, a new technology system for wood pyrolysis was developed to aim at mitigating climate change, global warming, and energy crisis as well as enhancing low electrification in rural areas in developing countries. The new technology system equipped with a pre-vacuum chamber requires low cost and less maintenance. However, large wood pyrolysis in the pre-vacuum chamber is rather complicated. To obtain a good understanding of the previous experimental results, a numerical analysis taking account of heat-mass transfer and chemical reaction is carried out. Two-step general reaction model is proposed for the numerical analysis. The first stage is volatile and char formation from the wood pieces and the second state is decomposition of the volatile to five species including vapor of tar. In this analysis, chemical formulae of the volatile and the tar are successfully identified hypothetically. The results obtained by this numerical analysis can explain the experimental results reasonably and provide useful information about time evolution of volatile formation, temperature change in pre-vacuum chamber with time, and species mole concentration decomposed from the volatile.

关键词： Pyrolysis Pre-Vacuum Chamber Chemical Reaction Volatile Sublimation ANSYS Fluent

Factors Influence on the Broaching Hammering Sound during Cementless Total Hip Arthroplasty

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Journal of Biomedical Science and Engineering 2022年第9期15卷 229-240页

作者： Xu Zhuang Yasuhiro homma Taichi Sato Tomonori Baba Itaru Morohashi Hideaki Iwase Kazuo Kaneko Muneaki Ishijima Department of Orthopaedic Surgery Juntendo University School of Medicine Tokyo Japan Department of Advanced Machinery Engineering Tokyo Denki University School of Engineering Tokyo Japan Department of Orthopaedic Surgery Juntendo University Shizuoka Hospital Shizuoka Japan Department of Bio-Engineering Shizuoka Medical Research Center for Disaster Juntendo University Shizuoka Hos-pital Shizuoka Japan

Background: The aim of this study is to identify the factors influence on the broaching hammering sound character during cementless total hip arthroplasty. Methods: We analyzed frequency spectrum of the hammering sound for 49 cases of uncomplicated cementless THAs using two types of proximal-coated stem performed by experienced surgeons. Normalized sound pressure (NSP) of each 0.5 kHz frequency band in final stage of broach procedure was determined by the fast Fourier transform analysis. The relationships between those sound characteristics and femoral morphology such as canal calcar ratio (CCR), Canal flare index (CFI), morphological cortical index (MCI) and femoral shaft length (FSL) in different cementless stem were investigated. Results: In Accolade 2, CCR was positively related to NSP in several bands [Frequency band (kHz);r: 2.0 - 2.5;0.37, 4.5 - 5.0;0.37, 9.5 - 10.0;0.44], and negatively related to 7.5 - 8.0 kHz (r = -0.39). Negative correlations were observed among CFI and MCI in specific frequency bands (4.5 - 5.0, 5.0 - 5.5, and 7.5 - 8.0 kHz). In Taperloc Microplasty, strong correlations were found between FSL and the NSP of 7.5. - 8.0 kHz (r = 0.78) and CCR and the 7.5 - 8.0 kHz bands. There was significant difference of NSPs between high and low group divided by morphological parameters. Acoustic characteristics of NSPs between Accolade 2 and Microplasty were significantly different in 9 frequency bands. Conclusions: The hammering sound correlated with four parameters of the femoral morphology and differed in different types of proximal-coated stem. Those novel five factors are important to consider when to predict complications using acoustic analysis.

关键词： Total Hip Arthroplasty Cementless Stem Hammering Sound Fast Fourier Transform Femoral Morphology

Effects of Secondary Chamber on Gas Yield by Pre-Vacuum Chamber Pyrolysis of Rubber Wood

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Journal of Sustainable Bioenergy Systems 2017年第1期7卷 1-13页

作者： Hiroki homma Hiroomi homma Sihar Siahaan Department of Mechanical Engineering Matsue College National Institute of Technology Matsue Japan Department of Mechanical Engineering University of North Sumatera Medan Indonesia Graduate School of Mechanical Engineering University of North Sumatera Medan Indonesia

Global warming awareness criticizes further usage of fossil fuels and insists promotion of renewable energy usage. Additionally, many people in rural areas of developing countries cannot access electricity. To solve this sort of energy crisis including global warming, current authors developed a proto-type of a pyrolysis plant equipped with a prevacuum chamber, which can be used to produce combustible gases for an engine generator in rural areas where people cannot access electricity. The plant is simple and easily maintained in consideration of special conditions that a rural area can receive very few maintenance service, technical assistance, and supply of spare parts. However, gas yield obtained by the proto-type of plant was around 20 wt% of feedstock. One way to enhance gas yield from this proto-type of plant is to utilize reaction of secondary tar cracking. This research work aims to examine possibility of gas yield enhancement keeping a simple structure of the proto-type of plant and using a simple technique of secondary tar cracking. Two tar cracking methods are examined: one is homogeneous tar cracking and the other is heterogeneous tar cracking using catalysis. In the homogeneous tar cracking, pyrolysis gases must be heated up to 650oC to 700oC and in the heterogeneous tar cracking, wood char is used as catalysis, because wood char is byproduct of pyrolysis. It is concluded that the homogeneous tar cracking is quite unlikely in the secondary chamber, but on the other hand, heterogeneous tar cracking using wood char can produce 30 wt% of gas yield from 1 kg of feedstock.

关键词： Secondary Chamber Pre-Vacuum Chamber Rubber Wood Secondary Tar Cracking Gas Yield Gas Component