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Local convergence zones or discontinuous lines in the Taklimakan Desert, Northwest China

第八届（2011）中国钢铁年会

作者： osamu ishiyama Kenichi Higuchi Kazuyuki Shinagawa Kohichi Ooyama Environmental and Process Technology Center Nippon Steel Corporation Yawata Works Nippon Steel Corporation

One of our key tasks in Tobata No. 3 Sinter Plant in Yawata Works, Nippon Steel Corp., is to reduce the consumption of expensive burnt lime, which is abundantly used to ensure the permeability of sinter beds. Conversely, as shown by many previous studies concerning the binder of raw material for sinter ore, no alternative to burnt lime has yet been developed and implemented. In this report, the development of a new binder that allows us to realize the intensified granulation of a raw material, its performance under lab-examination and the test operation of an actual plant are presented. Lab-examination results showed that the granular index can be improved when dispersant is added compounded together with micro-particles, and the highest effect on productivity improvement was identified in the pot test. An actual plant test was also implemented, targeting a reduction in burnt lime, through the improved permeability of sinter beds and with the intensified granulation of raw materials employing this new binder（micro-particles addition plus dispersant）. It was confirmed that a reduction of approximate 10 kg/t-sinter in burnt lime consumption unit could be achieved as productivity and sinter ore strength were maintained at an approximately constant level and operation stably secured. Meanwhile, the granulation index of the compounding raw materials and the permeability before ignition were retained at levels equivalent to those in the case of the base. Furthermore, synthetic binder consumption unit, including burnt lime and micro-particles additives, was reduced approximately 6 kg/t-sinter despite of adding micro-particle additives amounting to 4.3 kg/t-sinter.

关键词： granulation binder micro-particles

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Journal of Arid Land 2010年第2期2卷 77-86页

作者： Masatoshi YOSHINO Takashi ishiyama Jun SUZUKI Professor Emeritus University of Tsukuba Center for Environmental Remote Sensing Chiba University IDEA Consultants

In order to study convergence zones or discontinuous lines formed locally in the Taklimakan Desert,we analyzed available MODIS images onboad TERRA or AQUA satellite for ten cases:29 March 2002,14 April 2002;2 January 2003;21 April 2003;26 March 2004;28 April 2004;30 January 2005;25 June 2005;3 December 2005;and 26 July *** used weather maps published by the Japan Mete-orological Agency for the Asia and Pacific region at 500 hPa,700 hPa and 850 hPa,at 00Z and 12Z to analyze the meteorological conditions occurring in each *** estimated the positions of air streams,convergence zones or discontinuous lines between them,and thermal conditions on the maps and con-firmed the presence of cumulus and cumulonimbus clouds through satellite images in *** a review of previous studies,this paper introduced the results of the present *** warm areas in the Taklimakan Desert and on the Tibetan Plateau and local convergence zones or discontinuous lines in the Taklimakan Desert were discussed together with their diurnal changes,using composite maps of the ten *** the long axis of the desert the convergence zones or discontinuous lines normally extend 70-80 km in a west-east direction,but are suspected to exceed 100 km in extreme *** the other hand,the convergence zones or discontinuous lines extending in a north-south direction on the southern fringe of the desert have a length of 40-60 *** closed warm areas show clear diurnal changes,but they were not detected at the 500 hPa *** example of a clear convergence zone running in a north-south direction on 26 July 2006 was presented in detail with corresponding satellite images.

关键词： atmospheric circulation convergence zone discontinuous line satellite image Taklimakan Desert

Microscopic Investigation of Ethylene Carbonate Interface: A Molecular Dynamics and Vibrational Spectroscopic Study

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物理化学学报 2018年第10期34卷 1124-1135页

作者： WANG Lin XIN Liang ishiyama Tatsuya PENG Qiling YE Shen MORITA Akihiro Department of Chemistry Graduate School of Science Tohoku University Elements Strategy Initiative for Catalysts and Batteries (ESICB) Kyoto University Department of Applied Chemistry Graduate School of Science and Engineering University of Toyama Institute for Catalysis Hokkaido University

Ethylene carbonate(EC) liquid and its vapor-liquid interface were investigated using a combination of molecular dynamics(MD)simulation and vibrational IR, Raman and sum frequency generation(SFG)spectroscopies. The MD simulation was performed with a flexible and polarizable model of the EC molecule newly developed for the computation of vibrational spectra. The internal vibration of the model was described on the basis of the harmonic couplings of vibrational modes, including the anharmonicity and Fermi resonance coupling of C=O stretching. The polarizable model was represented by the charge response kernel(CRK),which is based on ab initio molecular orbital calculations and can be readily applied to other systems. The flexible and polarizable model can also accurately reproduce the structural and thermodynamic properties of EC liquid. Meanwhile, a comprehensive set of vibrational spectra of EC liquid, including the IR and Raman spectra of the bulk liquid as well as the SFG spectra of the liquid interface, were experimentally measured and reported. The set of experimental vibrational spectra provided valuable information for validating the model, and the MD simulation using the model comprehensively elucidates the observed vibrational IR, Raman, and SFG spectra of EC liquid. Further MD analysis of the interface region revealed that EC molecules tend to orientate themselves with the C=O bond parallel to the interface. The MD simulation explains the positive Im[χ^((2))](ssp) band of the C=O stretching region in the SFG spectrum in terms of the preferential orientation of EC molecules at the interface. This work also elucidates the distinct lineshapes of the C=O stretching band in the IR, Raman, and SFG spectra. The lineshapes of the C=O band are split by the Fermi resonance of the C=O fundamental and the overtone of skeletal stretching. The Fermi resonance of C=O stretching was fully analyzed using the empirical potential parameter shift analysis(EPSA) method. The appar

关键词： Ethylene carbonate SFG Fermi resonance EPSA

Determination of the Compound Biological Effectiveness (CBE) Factors Based on the ishiyama-IMAHORIDeterministic Parsing Model with the Dynamic PET Technique

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Journal of Cancer Therapy 2015年第8期6卷 759-766页

作者： Shintaro ishiyama Yoshio Imahori Jun Itami Hanna Koivunoro Quantum Beam Science Center Japan Atomic Energy Agency Tokai-mura Naka-gun Ibaraki Japan Cancer Intelligence Care Systems Inc. Koto-ku Ariake Tokyo Japan Department of Radiation Oncology National Cancer Center Tsukiji Chuo-ku Tokyo Japan Department of Oncology Helsinki University Central Hospital Helsinki Finland

Purpose: In defining the biological effects of the 10B(n, α)7Li neutron capture reaction, we have proposed a deterministic parsing model (ishiyama-IMAHORI model) to determine the Compound Biological Effectiveness (CBE) factor in Borono-Phenyl-Alanine (BPA)-mediated Boron Neutron Capture Therapy (BNCT). In present paper, we demonstrate a specific method of how the application of the case of application to actual patient data, which is founded on this model for tissues and tumor. Method: To determine the CBE factor, we derived the following new calculation formula founded on the deterministic parsing model with three constants, CBE0, F, n and the eigen value Nth/Nmax.? (1), where, Nth and Nmax are the threshold value of boron concentration of N and saturation boron density and CBE0, F and n are given as 0.5, 8 and 3, respectively. In order to determine Nth and Nmax in the formula, sigmoid logistic function was employed for 10B concentration data, Db(t) obtained by dynamic PET technique. (2), where, A, a and t0 are constants. Results and Conclusion: From the application of sigmoid function to dynamic PET data, it is concluded that the Nth and Nmax for tissue and tumor are identified with the parameter constants in the sigmoid function in Equation (2) as: (3). And the calculated CBE factor values obtained from Equation (1), with Nth/Nmax.

关键词： Boron Neutron Capture Therapy Compound Biological Effectiveness Borono-Phenyl-Alanine Tumor 10B(n α)7Li Sigmoid Function

Stent placement is effective on both postoperative hepatic arterial pseudoaneurysm and subsequent portal vein stricture:A case report

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World Journal of Gastroenterology 2007年第6期13卷 970-972页

作者： Toshiaki Ichihara Tsutomu Sato Hideaki Miyazawa Satoshi Shibata Manabu Hashimoto Koichi ishiyama Yuzo Yamamoto Departments of Gastroenterological Surgery and Radiology Akita University School of Medicine Hondo Akita 010-8543 Japan

To treat postoperative bleeding after hepato-pancreato-biliary surgery, interventional radiology has become essential. We report a case of coincidental pseudoan-eurysm and jejunal varices that were both successfully treated by stent-grafts. After a pancreaticoduodenec-tomy, the patient developed a pseudoaneurysm in the hepatic artery and a stenosis in its periphery. After establishing hepatic arterial flow by placing stent-grafts over both the pseudoaneurysm and the stenosis, the pseudoaneurysm was embolized with microcoils. Nine months later, the patient developed jejunal varices caused by a severe stricture in the main trunk of the portal vein. Percutaneous transhepatic portography was performed and stent-grafts were placed over the stenotic segment. A venoplasty using stent-grafts nor-malized the portal blood flow and the jejunal varices vanished. Although stenosis occurred due to scarred tissues from leakage after pancreaticoduodenectomy, stent-grafts were useful for managing jejunal bleeding post-operatively.

关键词： Extrahepatic portal vein stenosis Jejunalvarices Interventional radiology Stent-graft

Deterministic Parsing Model of the Compound Biological Effectiveness (CBE) Factor for Intracellular 10Boron Distribution in Boron Neutron Capture Therapy

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Journal of Cancer Therapy 2014年第14期5卷 1388-1398页

作者： Shintaro ishiyama Quantum Beam Science Directorate Japan Atomic Energy Agency Naka-gun Japan

Purpose: In defining the biological effects of the 10B(n, α)7Li neutron capture reaction, we have previously developed a deterministic parsing model to determine the Compound Biological Effectiveness (CBE) factor in Borono-Phenyl-Alanine (BPA)-mediated Boron Neutron Capture Therapy (BNCT). In present paper, we demonstrate that the CBE factor is directly and unambiguously derivable by the new formula for any case of intracellular 10Boron (10B) distribution, which is founded on this model for tissues and tumor. Method: To determine the CBE factor, we derive the following new calculation formula founded on the deterministic parsing model with three constants, CBE0, F, n and the eigen value Nth/Nmax. where, Nth and Nmax are the threshold value of boron concentration of N and saturation boron density in tissues and tumor. In order to determine these constants and the eigen values, iterative calculation technique was employed for the CEB factor and Nmax data set previously reported. Results and Conclusion: From the iterative calculation results, it is clear that the calculated CBE factor values obtained are almost identical to the original CBE factors and there is a good correlation between the original CBE factors and Nth/Nmax, when CBE0, F and n are given as 0.5, 8 and 3, respectively. These constants provide a better understanding of different types of intracellular10B distribution.

关键词： Boron Neutron Capture Therapy Compound Biological Effectiveness Borono-Phenyl-Alanine Tumor 10B(n α)7Li

Aluminum potassium sulfate and tannic acid sclerotherapy for Goligher Grades Ⅱ and Ⅲ hemorrhoids: Results from a multicenter study

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World Journal of Hepatology 2016年第20期8卷 844-849页

作者： Hidenori Miyamoto Takenori Hada Gentaro ishiyama Yoshito Ono Hideo Watanabe Department of Digestive and Pediatric Surgery Institute of Health Bioscience University of Tokushima Graduate School Department of Proctologic Surgery Shiseikai Miyamoto Hospital Division of Proctologic Surgery Onaka Clinic Oshiri Center Department of Anorectal Surgery Sapporo Ishiyama Hospital Department of Surgery Watanabe Hospital

AIM: To show that aluminum potassium sulfate and tannic acid(ALTA) sclerotherapy has a high success rate for Grade Ⅱ and Ⅲ ***: This study was based on the clinical data of 604 patients with hemorrhoids who underwent ALTA sclerotherapy between January 2009 and February 2015. The objective of this study was to assess the efficacy of this treatment for Grades Ⅱ and Ⅲ hemorrhoids. Preoperative and postoperative symptoms, complications and success rate were all assessed retrospectively. Follow-up consisted of a simple questionnaire, physical examination and an anoscopy. Patients were followed-up at one day, one week, two weeks, one month, one year, two years, three years, four years and five years after the ALTA ***: One hundred and sixty-nine patients were diagnosed with Grade Ⅱ hemorrhoids and 435 patients were diagnosed with Grade Ⅲ hemorrhoids. The one year, three year and five year cumulative success rates of ALTA sclerotherapy for Grades Ⅱ and Ⅲ hemo-rrhoids were 95.9% and 93.1%; 89.3% and 83.7%; and 89.3% and 78.2%, respectively. No significant differences were observed in the cumulative success rates after ALTA sclerotherapy between Grades Ⅱ and Ⅲ hemorrhoids(P = 0.09). There were forty-seven post-operative complications(low grade fever; anal pain; urinary retention; rectal ulcer; and others). No serious or life-threatening complications occurred and all cases improved through conservative treatment. At univariate analysis there were no predictive factors of ***: ALTA sclerotherapy has had a high success rate for Grade Ⅱ and Ⅲ hemorrhoids during five years of post-operative treatment. However, additional studies are needed to evaluate the efficacy of this ALTA sclerotherapy in the management of hemorrhoidal disease.

关键词： sclerotherapy Aluminum potassium sulfate and tannic acid Goligher grade Ⅲ Minimally invasive treatment Hemorrhoid

Pediatric ileoileal intussusception with a lipoma lead point:a case report

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Gastroenterology Report 2014年第1期2卷 70-72页

作者： Yoshihide Asaumi Tamon Miyanaga Yasuhiro ishiyama Masakazu Hattori Yasuo Hashizume Department of Surgery Fukui Prefectural HospitalFukuiJapan

Intussusception is a common cause of mechanical bowel obstruction among children,with older children being more likely to have a pathological lead *** neoplasms are rare and small intestinal lipomas are even less *** we describe a case of a 7-year-old boy with ileoileal intussusception,with an ileal lipoma as the pathological lead *** tomography was useful pre-operatively for revealing intussusception due to lipoma as the pathologic lead point.

关键词： Lipoma Intussusception Child

Radiation Sensitivity of in VitroEvaluation System of Pharmacokinetics in Boron Neutron Capture Therapy (BNCT) Using Three-Dimensional Artificial Human Tumor Tissue Model

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Journal of Cancer Therapy 2019年第12期10卷 1025-1035页

作者： Shintaro ishiyama Minoru Suzuki Faculty of Science and Technology Graduate School of Science and Technology Hirosaki University Bunkyo Hirosaki Aomori Japan Particle Radiation Oncology Research Center Institute for Integrated Radiation and Nuclear Science Kyoto University Asahiro-nishi Kumamori Sennan Osaka Japan

One of the important matters that must be determined in advance when performing BNCT treatment is the optimization of neutron irradiation time and dose. In this article, following the previous article (2.52 × 1012 n/cm2) (Case 1), double irradiation (5.04 × 1012 n/cm2) was further performed (Case 2) by verifying the radiation sensitivity performance of the artificial tumor tissue NHDF3D/BxPC3 and the possibility of evaluating the optimum neutron dose required for treatment was examined. As a result, although the radiation damage rate in the normal tissue NHDF3D and the tumor tissue BxPC3 increased in proportion to the irradiation dose due to heavy irradiation in Case 1 or more, the increase in the damage rate in the normal tissue exceeded the tumor tissue. Furthermore, the tumor/normal tissue damage ratio T/N ratio showed the maximum value in Case 1, and the dose ratio in Case 2 with a higher dose showed a tendency to decrease. From the above experimental facts, it was shown that irradiation dose optimization is possible to some extent by an evaluation method using an artificial tumor tissue.

关键词： Boron Neutron Capture Therapy (BNCT) Boronophenylalanine (10BPA) Artificial Human Tumor Tissue Model Cell Accumulation Method