检索结果-南通市图书馆

Comparison of 45- degree Kelman and 45- degree balanced phaco tip designs in torsional microcoaxial phacoemulsification

在线全文

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2015年第6期8卷 1168-1172页

作者： Süleyman Demircan Mustafa Atas Emre goktas Burhan Baskan Eye Clinic Kayseri Training and Research Hospital

AIMTo compare the intraoperative performance and postoperative outcome after microcoaxial torsional phacoemulsification using either a Kelman or balanced phaco *** were treated using 2.2 mm microcoaxial torsional phacoemulsification using either a 45-degree mini-flared Kelman® or a 45-degree Intrepid® Balanced phaco tip. Intraoperative measurements included total ultrasound (US) time, cumulative dissipated energy (CDE), torsional US time, and balanced salt solution (BSS) use. The central endothelial cell density (ECD) and central corneal thickness (CCT) were evaluated preoperatively and postoperatively 1, 7, and 30d after surgery using noncontact specular *** 116 enrolled eyes (116 patients) were divided equally between the Kelman and balanced tip groups. Intraoperative measurements showed significantly less total US time, torsional US time, CDE, and BSS use in the balanced group than in Kelman group (P<0.05). The total US time, torsional US time, CDE, and BSS use were 17.45±14.53s, 16.63±13.97s, 6.38±5.26, and 48.21±17.21 mL in the Kelman group and 11.39 ± 9.60s, 10.90 ± 9.25s, 4.04 ± 3.42, and 41.36 ± 12.70 mL in the balanced group, *** phacoemulsification performed with a balanced tip provided more effective lens removal with less total US time, torsional time, CDE, and BSS use, as well as similar changes in ECD with a Kelman tip in all cataract grades. This special designed phaco tip for torsional phacoemulsification provides an alternative phaco tip for many surgeons' preference with straight phaco tip.

关键词： phaco tip torsional phacoemulsification Kelman phaco tip balanced phaco tip

Ocular penetration of topically applied 1% tigecycline in a rabbit model

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2017年第5期10卷 679-683页

作者： Yasar Sakarya Rabia Sakarya Muammer Ozcimen Sertan goktas Serap Ozcimen Ismail Alpfidan Ismail Senol Ivacik Erkan Erdogan Servet Cetinkaya Abdulkadir Bukus Department of Ophthalmology Konya Training and Research Hospital Konya 42090 Turkey Department of Infectious Diseases and Clinical Microbiology Konya State Hospital Konya 42060 Turkey Department of Ophthalmology Konya Kizilay HospitalKonya 42200 Turkey

AIM：To evaluate ocular penetration of topically applied 1% ***：Forty-two New Zealand White rabbits were divided into 3 groups. A 50 μL drop of 1% tigecycline was administered in group 1. In groups 2 and 3, the drop was administered every 15 min for 60min（keratitis protocol）. Aqueous humor samples in groups 1 and 2 were collected under general anesthesia at 15, 30, 45, 60, 120, and 180 min after the last drop. All animals in group 3 were euthanatized. Cornea, vitreous and blood samples were collected 60 and 120 min after the last drop. Tigecycline concentrations were measured using high performance liquid chromatography-mass spectrometry（LC-MS/MS）.RESULTS：The peak aqueous humor tigecycline concentration [mean 0.73±0.14 mg/L（SD） and 2.41±0.14 mg/L, respectively] occurred 45 min after topical drug application in groups 1 and 2. Group 3 mean values in the cornea, and vitreous, were 3.27±0.50 μg/g, and 0.17±0.10 mg/L at 60 min and 3.17±0.77 μg/g and 0.20±0.07 mg/L at 120 min, respectively. Tigecycline serum concentrations were ***：Tigecycline levels in the aqueous humor in groups 1 and 2, and in the cornea in group 3 exceeded the minimum inhibitory concentrations of most grampositive organisms that cause bacterial keratitis and endophthalmitis.

关键词： antibiotic cornea pharmacokinetics aqueoushumor rabbit eyes

Impact of humic acids on the colonic microbiome in healthy volunteers

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2017年第5期23卷 885-890页

作者： Alexander Swidsinski Yvonne Dorffel Vera Loening-Baucke Christoph Gille Anne Reiβhauer Onder goktas Monika Krüger Jürgen Neuhaus Wieland Schrodl Laboratory for Molecular Genetics Polymicrobial Infections and BiofilmsDepartment of MedicineSection of GastroenterologyHepatology and EndocrinologyCharitéUniversitatsmedizin Berlin Outpatient Clinic Luisenstr.11-13CharitéUniversitatsmedizin Berlin entre for Infectious Diseases Faculty of Veterinary MedicineUniversity of Leipzig

AIMTo test the effects of humic acids on innate microbial communities of the *** followed the effects of oral supplementation with humic acids (Activomin®) on concentrations and composition of colonic microbiome in 14 healthy volunteers for 45 d. 3 × 800 mg Activomin® were taken orally for 10 d followed by 3 × 400 mg for 35 d. Colonic microbiota were investigated using multicolor fluorescence in situ hybridization (FISH) of Carnoy fixated and paraffin embedded stool cylinders. Two stool samples were collected a week prior to therapy and one stool sample on days 10, 31 and 45. Forty-one FISH probes representing different bacterial groups were *** sum concentration of colonic microbiota increased from 20% at day 10 to 30% by day 31 and remained stable until day 45 (32%) of humic acid supplementation (P 0.05). The others remained unaffected. Bacterial groups with initially marginal concentrations (9/mL) demonstrated no response to humic acids. The concentrations of pioneer groups of Bifidobacteriaceae, Enterobacteriaceae and Clostridium difficile increased but the observed differences were statistically not *** acids have a profound effect on healthy colonic microbiome and may be potentially interesting substances for the development of drugs that control the innate colonic microbiome.

关键词： Fluorescence in situ hybridization Colonic microbiota Colonic bioreactor Humic acids Healthy volunteers oral supplementation

后囊膜混浊及其治疗对SD-OCT测量视网膜神经纤维层厚度的影响（英文）

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

国际眼科杂志 2017年第2期17卷 209-212页

作者： Umit Calli Taha Ayyildiz Genc Selim Eren goktas Muhammed Nurullah Bulut Umraniye研究培训医院眼科土耳其伊斯坦布尔34766 Haydarpasa Numune研究培训医院眼科土耳其伊斯坦布尔34668 Kanal Dr.L.Kirdar研究培训医院眼科土耳其伊斯坦布尔34890

目的:研究后囊膜混浊(posterior capsular opacity,PCO)及其治疗对使用谱域光学相干断层扫描(spectral domain optical coherence tomography,SD-OCT)测量视网膜神经纤维层(retinal nerve fiber layer,RNFL)厚度的影响。方法:使用SD-OCT测量50例接受Nd:YAG激光后囊膜切开术患者术前和术后RNFL厚度。通过信噪比(signal to noise ratio,SNR)等级,将患者分为组1(SNR 3和4)、组2(SNR 5和6)及组3(SNR 7和8)。对侧眼作为对照组。结果:接受了Nd:YAG激光后囊膜切开术的眼BCVA、SNR和RNFL均值显著增加。组1和组2激光治疗前后BCVA、SNR和RNFL均值显著不同。尽管组3中患者治疗前后BCVA和SNR均值显著不同,RNFL厚度在治疗前后没有显著差异。结论:PCO对OCT图像质量有影响。所有接受后囊膜切开术的患者,术后SNR较术前有所改善。治疗前SNR7在以下的患者中,RNFL厚度在患者接受Nd:YAG激光后囊膜切开术后显著提高。

关键词：囊膜混浊神经纤维激光固态光学相干断层成像后囊膜切开术

Pentacam Scheimpflug成像测量晶状体密度与torsional超声乳化参数间的关系（英文）

在线全文

学校读者我要写书评

暂无评论

国际眼科杂志 2014年第10期14卷 1739-1743页

作者： Suleyman Demircan Mustafa Atas Murat Koksal Emine Pangal Isa Yuvaci Altan goktas 开赛里培训研究医院眼科土耳其开赛里138010 开赛里Modern Dunya医院土耳其开赛里238010

目的：评价运用Pentacam Scheimpflug成像测量晶状体核密度与torsinal超声乳化动力学参数（如：运用于老年核性白内障患者的超声能量水平、液体留存时间及液体量）间的关系。方法：此研究为前瞻性双盲研究。瞳孔扩大后运用Pentacam Sche... 详细信息

目的：评价运用Pentacam Scheimpflug成像测量晶状体核密度与torsinal超声乳化动力学参数（如：运用于老年核性白内障患者的超声能量水平、液体留存时间及液体量）间的关系。方法：此研究为前瞻性双盲研究。瞳孔扩大后运用Pentacam Scheimpflug 成像进行测量。白内障的等级由pentacam核密度测定法[ pentacam nucleus densitometry, PND；又名Pentacam核分段（ Pentacam nucleus staging, PNS）软件]自主分为1到5个等级。超声乳化术后,自动在Infiniti Ozil IP超声乳化系统监视器上计算并显示总超声（ U/S）时间、累计耗散能、Torsional U/S时间以及估算液体的使用情况。组间差异运用单因素方差分析（ ANOVA ）进行评定,多组分析运用Tamhane测试法,PND测量的晶状体密度与torsinal超声乳化动力学参数间的关系运用Spearman相关分析进行评定。界定P〈0.05时具有统计学意义。结果：此项研究包括125例患者（125眼）,平均年龄为69.7±9.4岁（范围：48~88岁）,其中61例男性、64例女性。 U/S总时间、torsional U/S时间、CDE及估算液体使用情况的范围分别为0.70~158.9s,0.70~158.5s,0.11~42.65和21~98mL. PND组间数据有统计学差异。评估超声乳化动力学参数与PND数据间关系后得出PND数据与总超声时间（ r=0.767； P〈0.01）、torsional超声时间（r=0.767；P〈0.01）、CDE（r=0.758； P〈0.01）及液体使用量（r=0.602；P〈0.01）均有显著相关性。结论：白内障手术前运用PND评分法获得核密度的客观程度可为超声乳化术中的参数提供可靠的预见性。因此,对每一位患者进行每一单项超声乳化参数的评估,有助于降低超声乳化能量的使用量,减少内皮细胞丢失和类固醇的使用,加速视力的恢复。

关键词： torsional超声乳化 pentacam 沙氏成像晶状体密度测定

比较21G弯头和直头在横向劈核微切口同轴超声乳化手术中的应用(英文)

在线全文

学校读者我要写书评

暂无评论

国际眼科杂志 2015年第12期15卷 2029-2035页

作者： Süleyman Demircan Mustafa Atas Emre goktas Burhan Baskan Gokmen Zararsiz 开塞利培训与研究医院眼科门诊土耳其开塞利38010 埃尔吉耶斯大学生物统计学系土耳其开塞利38010

目的:比较在微切口同轴扭动超声乳化使用直头和弯头的术中表现和术后结果。方法:白内障患者行2.2mm横向劈核微切口同轴超声乳化术中使用30°直头或弯头进行治疗。术中检查分析包括平均超声功率,总超声乳化时间,有效的超声乳化时间。使... 详细信息

目的:比较在微切口同轴扭动超声乳化使用直头和弯头的术中表现和术后结果。方法:白内障患者行2.2mm横向劈核微切口同轴超声乳化术中使用30°直头或弯头进行治疗。术中检查分析包括平均超声功率,总超声乳化时间,有效的超声乳化时间。使用非接触镜显微镜评估术前和术后1d,7d和30d的中央内皮细胞密度和角膜中央厚度。结果:此研究共纳入白内障患者190例190眼,95眼为弯头组,95眼为直头组。术中检查显示弯头组总超声乳化时间和有效的超声乳化时间较直头组显著降低(P<0.05)。弯头组总超声乳化时间和有效的超声乳化时间中位数分别为25.9(13.5-45.0)s(四分位间距)和18.0(9.0-30.0)s,直头组分别为38.8(16.5-73.5)s和26.0(11.0-49.0)s。结论:横向劈核微切口同轴超声乳化术中,相比较直头,使用弯头可以更加有效的摘除晶体,在所有阶段中除了第四阶段,总超声乳化时间和有效的超声乳化时间更短。

关键词：横向劈核微切口同轴超声乳化弯头直头微切口同轴超声乳化

在线全文

学校读者我要写书评

暂无评论

窄波UVB联合局部外用钙泊三醇治疗白癜风

世界核心医学期刊文摘（皮肤病学分册） 2006年第9期2卷 4-4页

作者： goktas E.O. Aydin F. Senturk N. 冯义国 Ondokuz Mayis University School of Medicine Department of Dermatology TR- 55139 Kurupelit Samsun Turkey

Background: Narrow band ultraviolet B (NB-UVB) phototherapy has been used successfully for the treatment of vitiligo. Recently, topical calcipotriol has also been claimed to be effective, either as monotherapy or as a part of combination therapies. Objective: The aimof the present studywas to compare the clinical efficacy of NB-UVB and NB-UVB plus topical calcipotriol in the treatment of vitiligo. Methods: NB-UVB treatment was given to 24 patientswith generalized vitiligo three times weekly. Topical calcipotriol cream was only applied to the lesions located on the right side of the body. Treatment was continued for 6 months. Treatment efficacy was evaluated by determining the average response rates of the lesions at 3-month intervals. Result: The average response rates of patients receiving combination of NB-UVB plus calcipotriol and NB-UVB alone were 51 ± 19.6% and 39 ± 18.9% , respectively. The median cumulative UVB dose and number of UVB exposures for initial repigmentation were 6345 mj/cm2 (range; 2930- 30980) and 18 (range; 12- 67) for the combination therapy, and 8867.5 mj/cm2 (range; 2500- 30980) and 24 (range; 15- 67) for the narrow band UVB therapy, respectively. Conclusions: These findings indicate that concurrent topical calcipotriol potentates the efficacy of NB-UVB in the treatment of vitiligo. This combination not only provides earlier pigmentation with lower total UVB dosage and less adverse UVB effects, but also reduces the duration and cost of treatment as well.

关键词： UVB照射有效治疗钙泊三醇局部外用白癜风临床疗效色素沉着累积剂量