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Hydrocephalus Secondary to Intraventricular Myxopapillary Ependymoma: Case Report

World Journal of Neuroscience 2024年第3期14卷 85-91页

作者： Juan Carlos Ayala-Alvarez onyekachi emmanuel anyagwa Fátima Gabriela Macías-Ortiz Oluwatoyin Adalia Dairo Courtney Storm Truebody Reza Badrnejad Aishwarya Bhuta Shashwat Sandeep Phade Srushti Kishor Jamdar Mostafa Yassin Vismaja Vijayan Neurology Department Hospital Civil Fray Antonio Alcalde Guadalajara Jalisco Mxico School of Medicine New Vision University Tbilisi Georgia

Ependymomas are a somewhat diverse category of glial tumors that often develop from the lining of the brain’s ventricles, or the spinal cord’s central canal. They make up 5% of all neuroepithelial tumors, 10% of paediatric brain tumors, and up to 33% of brain tumors in children under the age of three. Hydrocephalus is one of the complications, and it can be identified as progressive macrocephaly or increasing head circumference crossing percentiles, nausea, vomiting, poor appetite, irritability, and regression of developmental milestones.

关键词： Hydrocephalus Myxopapillary Ependymoma (MPE) Paediatrics Neurosurgery Glioma Intracranial Hypertension

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Extended Fasting Durations Delayed Gastric Emptying and Colonic Motility in Normal Male Rats

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Journal of Biosciences and Medicines 2022年第7期10卷 146-154页

作者： Olugbenga Adeola Odukanmi onyekachi emmanuel anyagwa Omowunmi Sidikat Adewunmi Keren Ifunanya Okechukwu Samuel Babafemi Olaleye Department of Physiology University of Ibadan Ibadan Nigeria

Background: Previous studies on fasting and gastrointestinal motility were reported with information lacking concerning prolonged continuous fasting and gastrointestinal motility. This study investigated the effect of prolonged fasting duration on gastrointestinal motility. Methods: Forty-five (45) male Wistar rats, with body weights between 180 - 200 g were used. They were randomly assigned into three (3) groups. Group1: control (rats fasted for 18 h—common duration of fasting for motility studies), groups 2 and 3 fasted for 48 and 72 h respectively. Five (5) rats per experiment and per group were considered. Blood glucose was determined by glucose oxidase method, gastric emptying was assessed by hydrated carbohydrate meal, intestinal motility by charcoal meal, and colonic motility was assessed using bead test. Data were reported in Mean ± SEM and analyzed with one-way ANOVA. Differences in results were considered significant at p ≤ 0.05. Results: There was no significant change in the blood glucose level (mmol/L) of rats in the 48 h group (2.94 ± 0.35) and 72 h group (3.20 ± 0.32) as compared with the control (3.62 ± 0.19). There was a significant decrease in the rate of gastric emptying (g) in the 72 h group (0.20 ± 0.08) compared with the control (0.64 ± 0.16). The intestinal transit (cm) in the 48 h group (67.54 ± 6.15) and 72 h group (72.10 ± 7.60) increased significantly when compared with the control (42.14 ± 3.14). There was a significant decrease in the colonic motility time (Sec.) in the 48 h group (2707 ± 864.1) and 72 h group (6363 ± 968.1) when compared with the control (263.8 ± 64.26). Conclusion: Extended fasting durations decrease the rate of gastric emptying and colonic motility. It suggests that extended fasting durations could be beneficial in intestinal spasms or where the gut is required to relax.

关键词： Fasting Gastrointestinal Motility Gastric Emptying Intestinal Transit Colonic Motility Rats

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