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Health 2010年第7期2卷 692-695页

作者： Ismail Dursun Faysal Gok Oguzhan Babacan Erkan Sari onur sakallioglu Suleyman Kalman Ibrahim Gokce Department of Pediatric Nephrology and Rheumatology Gulhane Military Medical AcademySchool of MedicineAnkaraTurkey Department of Pediatrics Gulhane Military Medical AcademySchool of MedicineAnkaraTurkey

The present study aimed to investigate the correlation of MPV and splenomegaly as inflammation activity of FMF patients at the attacks free period. We retrospectively reviewed the medical records of 43 patients with FMF. This study was performed at the attack free period as clinical and laboratory. For this study, patients were divided into two groups. Patients with splenomegaly is called group 1 (n = 12) and patients with no splenomegaly is called group 2 (n = 31). Groups were compared respect to age, gender, platelet counts, acute phase reactants and MPV. The mean MPV (fl) were significantly higher in group 1 (8.9 ±0.8) than in group 2 (8.4 ±0.5, p <0.05). This study suggested that increased MPV and splenomegaly without amyloidosis could be a sign of chronic inflammation in children with FMF even in attack free period.

关键词： Familial Mediterranean Fever Mean Platelet Volume Subclinical Inflammation

An integrated spatial planning of the mountainous landscapes for ski sports in a case area at the eastern Türkiye

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Journal of Mountain Science 2024年第3期21卷 754-767页

作者： SATIR onur TOSUN Busra COSKUN OZYOL Funda OZDEMIR Omer Faruk BERBEROGLU Suha Dept.of Landscape Architecture Van Yuzuncu Yil UniversityVan 65090Türkiye School of Physical Education&Sports Van Yuzuncu Yil UniversityVan 65090Türkiye Van Yuzuncu Yil University Dept.of Architecture&Urban Planning Van 65090Türkiye Dept.of Remote Sensing&GIS Cukurova UniversityAdana 01330Türkiye

Mountainous regions have disadvantages in economic development because of harsh physical and climatic ***,winter tourism activities are one of the key components for supporting economic development in the *** a ski resort area supports direct and indirect employment in a region,and it stops immigration from mountainous regions to other *** research aimed to assess the potential ski areas using a multi criteria evaluation technique in the Van region which is located in the eastern part of Tü*** this context,snow cover duration,sun effect,slope,slope length,elevation,population density,distance from main roads and lake visibility were used as input factors in the decision making *** factor was standardized using a fuzzy technique based on existing well-known ski centers in Tü*** weight of inputs was defined by applying a survey to the professional *** most important factors were detected as transportation opportunities and snow covers whereas,the least important factors were elevation and population ***,lake visibility was very important to make a difference from other existing facilities in the ***,it was included as constraints and lake visible areas were extracted at the final stage of the *** ski areas were mapped in three levels as professional,intermediate and beginner *** of the suitable areas was selected as a sample projection and for the 3D simulation of the ski investment *** costs and benefits were *** was found that a ski tourism area investment can be amortized in 3 years in the region.

关键词： Winter sports and tourism Decision making 3D simulation and modelling Landscape planning GIS

Rare-earth Magnet Free Flux-switching Generator for Wind Turbines in Micro-grids:A Review

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CES Transactions on Electrical Machines and Systems 2024年第3期8卷 295-309页

作者： Tugberk Ozmen BatıEren Ergun Mehmet onur Gulbahce Nevzat Onat Vocational School of Manisa Technical Sciences Manisa 45140Turkey department of Electrical Engineering Istanbul Technical UniversityIstanbul 34469Turkey Department of Electrical and Electronics Engineering University of Manisa Celal Bayar UniversityManisa 45140Turkey

In traditional electricity generation plants,large powerful synchronous,induction,and direct current generators were *** the proliferation of microgrids focused on electricity generation from renewable energy sources in today’s power grids,studies have been conducted on different types of *** of the traditional generator architecture,generators with brushless structures,particularly those utilizing magnets for excitation,have found broad *** generators(FSGs)are innovative types owing to their robust structure,active stator design,and high power density ***,designs have typically relied on rare-earth element ***-earth magnets possess negative characteristics such as price uncertainty,the potential risk of scarcity in the future,and limited geographical production,leading to research on FSGs that do not depend on rare-earth *** study comprehensively examines FSGs that do not use rare-earth element *** study delves into the usage areas,operational mechanisms,structural diversities,and counterparts in the literature of these generators.

关键词： Flux-switching Generator Micro-grid Wind energy

Role of biomarkers in community-acquired pneumonia management

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Journal of Acute Disease 2024年第3期13卷 87-92页

作者： Bahaeddin onur Hakan BarışDemirbas Arif Gulmez Department of Emergency Medicine Istanbul Health and Technology UniversityIstanbulTurkey Department of Emergency PHCCAl Karaana Health CenterDohaQatar Department of Emergency PHCCUmm Slala Health CenterDohaQatar Department of Family Medicine PHCCAl Thumama Health CenterDohaQatar

Community-acquired pneumonia(CAP)poses a significant global health threat,particularly affecting vulnerable *** and scoring systems play a crucial role in diagnosing,assessing severity,and guiding treatment decisions for CAP *** like C reactive protein,procalcitonin,and the neutrophil-to-lymphocyte ratio aid in diagnosis and severity assessment,while scoring systems such as CURB-65 and Pneumonia Severity Index classify patients into risk *** biomarkers(uremia,elevated respiratory rate,hypotension,and age≥65)like serum amyloid A and S100 proteins show promise in predicting disease severity and ***,further research is needed to determine their precise roles and clinical utility in CAP management.

关键词： CURB-65 Community-acquired pneumonia Procalcitonin Alpha-1 antitrypsin Serum amyloid A

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Message from Editors

CES Transactions on Electrical Machines and Systems 2024年第3期8卷 241-243页

作者： Tayfun GUNDOGDU Udochukwu B.AKURU Zhongze WU Guven KOMURGOZ Erkan MESE Okan OZGONENEL Ozan KEYSAN Mehmet onur GULBAHCE Department of Electrical Engineering Tshwane University of Technology South Africa Southeast University Istanbul Technical University Ege University Ondokuz Mayis University Middle East Technical University

AS the world embarks on a path toward electrification and strives to achieve net-zero greenhouse gas emissions,the role of electrical machines becomes increasingly vital across various *** urgent need for decarbonization and improved energy efficiency has directed attention to rare-earth-free electrical machines as a promising *** technologies offer a sustainable alternative to permanent magnet-based machines,which rely heavily on rare earth materials like neodymium and *** extraction and processing of these materials result in hazardous by-products that cause significant ecological harm,particularly near mining sites and refineries.

关键词： solution rare earth

Effect of acetyl L-carnitine on human retinal pigment epithelium-19 cells in hypoxic conditions

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国际眼科杂志 2024年第10期24卷 1515-1521页

作者： Ali Dal onur Catak Murat Erdag Mehmet Canleblebici Ebru Onalan Ilay Buran Department of Ophthalmology Faculty of MedicineFirat UniversityElazig 23119Turkey Department of Ophthalmology Ata Sokmen Faculty of MedicineMustafa Kemal UniversityHatay 31100Turkey Department of Ophthalmology Kayseri State HospitalKayseri 38200Turkey Department of Medical Biology Faculty of MedicineFirat UniversityElazig 23100Turkey

AIM:To investigate the effect of acetyl-L-carnitine(ALCAR)on cell viability,morphological integrity,and vascular endothelial growth factor(VEGF)expression in human retinal pigment epithelium(ARPE-19)cells using a hypoxic ***:In the first set of experiments,the optimal CoCl_(2) dose was determined by exposing ARPE-19 cell cultures to different *** evaluate the effect of ALCAR on cell viability,five groups of ARPE-19 cell culture were established that included a control group,a sham group(200μM CoCl_(2)),and groups that received 1,10 and 100 mM doses of ALCAR combined with 200μM CoCl_(2),*** cell viability was measured by MTT *** morphological characteristics of cells were observed by an inverted phase contrast *** levels of VEGF and HIF-1α secretion by ARPE-19 cells were detected by enzyme linked immunosorbent assay(ELISA)***:ARPE-19 cells were exposed to different doses of CoCl_(2) in order to create a hypoxia ***,when exposed to a concentration of 200μM CoCl_(2),a notable decrease in viability to 83% was *** was found to increase the cell viability at 1 mM and 10 mM concentrations,while the highest concentration(100 mM)did not have an added *** cell viability was found to be significantly higher in the groups treated with a concentration of 1 mM and 10 mM ALCAR compared to the Sham group(P=0.041,P=0.019,respectively).The cell viability and morphology remained unaffected by the greatest dose of ALCAR(100 mM).The administration of 10 mM ALCAR demonstrated a statistically significant reduction in the levels of VEGF and HIF-1α compared with the Sham group(P=0.013,P=0.033,respectively).CONCLUSION:The findings from the current study indicate that ALCAR could represent a viable therapeutic option with the potential to open up novel treatment pathways for retinal diseases,particular relevance for age-related macular degeneration(AMD).However,to fully elucidate ALCAR’s application

关键词： acetyl-L-carnitine(ALCAR) human retinal pigment epithelium(ARPE-19) vascular endothelial growth factor(VEGF) hypoxia-inducible factor 1(HIF-1α)

Radiological findings of February 2023 twin earthquakes-related spine injuries

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World Journal of Radiology 2024年第9期16卷 398-406页

作者： Ayşenur Bolukçu Ahmet Gürkan Erdemir İlkay Sedakatİdilman Adalet Elçin Yildiz GökçenÇobanÇifçi Mehmet Ruhi onur Erhan Akpinar Department of Radiology Hacettepe UniversityFaculty of MedicineAnkara 06100Türkiye Department of Radiology University of ChicagoChicagoIL 60637United States

BACKGROUND The February 6,2023,twin earthquakes in Türkiye caused significant structural damage and a high number of injuries,particularly affecting the spine,which underscores the importance of understanding the distribution and nature of vertebral injuries in disaster *** To investigate the distribution of radiological findings of vertebral injuries in patients referred to a major tertiary center during the February 6,2023 twin earthquakes in Tü*** With the approval of the institutional ethics committee,1216 examinations of 238 patients transferred from the region to a tertiary major hospital after the twin earthquakes of February 6,2023,were retrospectively analyzed for spine *** Spine computed tomography(CT)scans were performed in 192 of 238 patients with a suspected spinal injury,42 of whom also had an magnetic resonance imaging(MRI).In 86 of 192 patients(44.79%;M:F=33:53)a spinal fracture was detected on CT and in 33 of 42 patients(78.57%;M:F=20:13)a spinal injury was found on *** the 86 patients in whom vertebral injury was detected,fractures were detected in the Denis-B group in 33,Denis-C in 4,Denis-D in 20 and Denis-E in 11 *** the vertebral bodies:40"compression fractures",17"burst fractures",5"translational dislocation fractures",5"flexion-distraction fractures"and 58"prolonged forced fetal posture fractures"were *** addition,isolated transverse or spinous process fractures were found in eighteen *** Our study highlights the prevalence and diverse spectrum of spinal injuries following the February 6,2023 twin earthquakes in Turkey underscoring the urgent need for effective management strategies in similar disaster scenarios,and emphasizing the"prolonged forced fetal posture"damage we encountered in earthquake victims who remained under the collapse for a long time.

关键词： Accidental injuries Compression fractures Crush injuries Earthquakes Spine

Derivation of energy-based base shear force coefficient considering hysteretic behavior and P-delta effects

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Earthquake Engineering and Engineering Vibration 2018年第1期17卷 149-163页

作者： Taner Ucar onur Merter Department of Architecture Dokuz Eylul University Department of Civil Engineering Dokuz Eylul University

A modified energy-balance equation accounting for P-delta effects and hysteretic behavior of reinforced concrete members is derived. Reduced hysteretic properties of structural components due to combined stiffness and strength degradation and pinching effects, and hysteretic damping are taken into account in a simple manner by utilizing plastic energy and seismic input energy modification factors. Having a pre-selected yield mechanism, energy balance of structure in inelastic range is considered. P-delta effects are included in derived equation by adding the external work of gravity loads to the work of equivalent inertia forces and equating the total external work to the modified plastic energy. Earthquake energy input to multi degree of freedom（MDOF） system is approximated by using the modal energy-decomposition. Energybased base shear coefficients are verified by means of both pushover analysis and nonlinear time history（NLTH） analysis of several RC frames having different number of stories. NLTH analyses of frames are performed by using the time histories of ten scaled ground motions compatible with elastic design acceleration spectrum and fulfilling duration/amplitude related requirements of Turkish Seismic Design Code. The observed correlation between energy-based base shear force coefficients and the average base shear force coefficients of NLTH analyses provides a reasonable confidence in estimation of nonlinear base shear force capacity of frames by using the derived equation.

关键词： energy-based base shear force coefficient reduced hysteretic behavior P-delta effect pushover analysis nonlinear time history analysis

An approach for optimization of the wall thickness (weight) of a thick-walled cylinder under axially non-uniform internal service pressure distribution

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Defence Technology（防务技术） 2017年第3期13卷 150-157页

作者： onur Güngor MKE Kurumu Mühimmat Fabrikas Ar-Ge Müdürlügü 71100 Merkez

Today, improving the weight/load carrying capacity ratio of a part is the matter of studies in most of the scientific and industrial *** dimensions, the amount of material removed from outer and inner radius while manufacturing and the service pressure applied affect the residual stress distribution throughout the wall thickness and hence the load-bearing capacity of a thick-walled cylinder. Calculation of residual stresses after autofrettage process and optimization of autofrettage outline dimensions by using the amount of service pressures applied are common issues in *** this study, mandrel-cylinder tube interference dimensions were renovated by using traditional methods for swage autofrettage process of a gun barrel. Also, the residual stresses in the cylinder after autofrettage process, inside and outside material removal process and the variable service pressure throughout the cylinder applied were taken into consideration and incorporated into the design. By using the constrained optimization method, wall thickness(thus the weight) was optimized(minimized)to achieve the specified safety factor along the length of the cylinder. For the same cylinder, the results of the suggested analytical/with residual stress calculation approach were compared to analytical/without residual stress calculation results and numerical topology optimization method calculation results. Since the experimental measurement results are not yet available, it was not possible to compare them with the calculation *** suggested approach enabled 22.9% extra weight reduction in proportion to numerical topology optimization and enabled 4.2% extra weight reduction in proportion to analytical/without residual stress *** this approach, the gain from residual stresses after autofrettage operation, the loss of residual stresses after material removal, and the effects of service pressures can be taken into account for each stage of design.

关键词：尺寸优化圆筒壁厚厚壁圆筒载重量残余应力分析非均匀应力计算方法自增强材料

Determination of discontinuities in marble blocks via a nondestructive ultrasonic technique

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International Journal of Minerals,Metallurgy and Materials 2009年第5期16卷 487-493页

作者： Ahmet Hakan onur Sefa Bakrac Faculty of Engineering Mining Engineering DepartmentDokuz Eylul University35160 Tinaztepe BucaIzmirTurkey MSc in Mining Engineering Turkish General Directorate of Mineral Research and ExplorationIstanbul Cad. No.63 Bornova IzmirTurkey

Miners working in the marble industry have always been interested in identifying structural weaknesses in marble blocks before they are transported to marble processing plants. To achieve this difficult task, several simple methods have been developed among miners but observation-based methods do not consistently provide satisfactory results. A nondestructive method developed for testing concrete could be used for this purpose. In this study, this simple method based on differences in ultrasonic wave propagation in different materials was presented, and the test results performed both in the laboratory and a marble quarry were discussed.

关键词： nondestructive test marble discontinuity ultrasonic wave