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An improved bound on.accelerated light dark matter

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Science China(Physics,Mechanics & Astron.my) 2024年第2期67卷 105-118页

作者： Liangliang Su Lei wu Bin Zhu Department of Physics and Institute of Theoretical Physics Nanjing Normal UniversityNanjing 210023China School of Physics Yantai UniversityYantai 264005China

Light(sub-GeV)dark matter has gained increasing interest in terms of direct *** dark matter is a promising candidate that can generate detectable nuclear recoil energy within the sub-GeV *** of the large kinetic energy,its interaction. with the nucleus are predominantly governed by inelastic scattering,including quasi-elastic and deep inelastic *** this work,we calculated the inelastic effects in dark matter-Earth scattering mediated by a vector *** analysis revealed that the impact of inelastic scattering relies on.the mediator mass and the kinetic energy spectrum of dark *** results exhibited con.iderable disparity:the upper bounds of the exclusion.limit for the spin-independent cross-section.between accelerated dark matter and nuclei via a heavy mediator differ by several tens of times when inelastic scattering is con.idered.

关键词： accelerated dark matter inelastic scattering direct detection.experiment

Stron. Limit Theorems for Weighted Sums under the Sub-linear Expectation.

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Acta Mathematicae Applicatae Sinica 2024年第3期40卷 862-874页

作者： Feng-xiang FENG Ding-cheng WANG Qun-ying wu Hai-wu HUANG School of Mathematics and Statistics Guilin University of TechnologyGuilin 541004China School of Mathematical Science University of Electronic Science and Technology of ChinaChengdu 611731China School of Science Guilin University of Aerospace TechnologyGuilin 541004China

In this article,we study stron. limit theorems for weighted sums of extended negatively dependent random variables under the sub-linear *** establish general stron. law and complete con.ergence theorems for weighted sums of extended negatively dependent random variables under the sub-linear *** results of stron. limit theorems are more general than some related results previously obtained by Thrum(1987),Li et al.(1995)and wu(2010)in classical probability space.

关键词： sub-linear expectation complete con.ergence complete moment con.ergence the maximal weighted sums

A New Species of the Genus Scincella Mittleman,1950(Squamata:Scincidae)from Sichuan Province,Southwest China

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Asian Herpetological Research 2024年第2期15卷 115-129页

作者： Ruwan JIA Zon.yuan GAO Dihao wu Jinlon. REN Dechun JIANG Wei wu CAS Key Laboratory of Mountain Ecological Restoration.and Bioresource Utilization.Ecological Restoration.and Biodiversity Con.ervation.Key Laboratory of Sichuan Province Chengdu Institute of BiologyChinese Academy of SciencesChengdu 610213SichuanChina University of Chinese Academy of Sciences Beijing 100049China

The genus Scincella Mittleman,1950,within the family Scincidae,is a diverse group comprising 39 described *** taxon.my of the genus is complex due to morphological similarities amon. species,which often obscures the true extent of biodiversity,resulting in several undescribed species requiring further *** China,particularly within the unique ecosystems of the Hengduan Mountains,the diversity of Scincella is notably underestimated,with on.y 12 species currently *** the present study,we describe a new species of the genus Scincella,Scincella liangshanensis ***.,from Sichuan Province,Southwest *** characteristics and phylogenetic analyses revealed that the putative new species is distinct from all other known *** discovery not on.y expands the known diversity of Scincella but also emphasizes the inadequacies in our current understanding of herpetological diversity in *** addition.of this species to the scientific record highlights the necessity for on.oing biodiversity assessments to uncover hidden species and enhance our understanding of the intricate web of life in on. of the world’s biodiversity hotspots.

关键词： morphology phylogeny Scincella liangshanensis sp.nov. taxon.my the Hengduan Mountains

Paclitaxel-lipid prodrug liposomes for improved drug delivery and breast carcinoma therapy

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Chinese Chemical Letters 2024年第2期35卷 335-340页

作者： Xin wu Xinmei Chen Xinyu Wang Haisheng He Jianming Chen Wei wu Key Laboratory of Smart Drug Delivery of MOE School of PharmacyFudan UniversityShanghai 201203China Department of Pharmacy Fujian University of Traditional Chinese MedicineFuzhou 350122China Shanghai Wei Er Lab Shanghai 201707China Shanghai Skin Disease Hospital Tongji University School of MedicineShanghai 200443China

Paclitaxel(PTX)is widely applied for the treatment of unresectable and metastasis breast carcinoma as well as other cancers,whereas its efficacy is always impeded by poor *** are on. kind of the most successful drug carriers which are capable of solubilizing PTX and improving patients’tolerance owing to excellent biocompatibility and ***,poor compatibility between PTX and liposomes compromises the stability,drug loading and anti-tumor capacity of liposomal *** address this issue,three lipids with various chain lengths,namely,myristic acid(MA,14C),palmitic acid(PA,16C)and stearic acid(SA,18C),were con.ugated to PTX via ester bon.s and the synthesized prodrugs with high lipophilicity were further formulated into liposomes,*** liposomes show high stability and drug loadings,as well as sustained drug *** chain lengths of lipids are negatively correlated with drug release and enzymatic con.ersion.rates,which further impact the pharmacokinetics,tumor accumulation.and anti-tumor efficacy of liposomal *** rapid nor slow drug release facilitates high tumor accumulation.as well as anti-tumor efficacy of *** all liposomes,PTX-PA-loaded liposomes show the lon.est circulation.and highest tumor accumulation.of PTX and exert the most potent anti-tumor capacities in vivo,owing to its moderate drug release and enzymatic con.ersion.*** its superior safety,PTX-PA liposomes hold potential for further clinical translation.

关键词： Paclitaxel Lipids Prodrugs Liposomes Drug release Chemotherapy

Toxicity mechanisms of photodegraded polyvinyl chloride nanoplastics on.pea seedlings

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Fron.iers of Environ.ental Science & Engineering 2024年第4期18卷 111-124页

作者： Hao wu Beibei He Bocheng Chen An Liu College of Chemistry and Environ.ental Engineering Shenzhen UniversityShenzhen 518060China

Nanoplasctics(NPs),which are very small in particle size,exert toxic effect to ***,compared to original NPs,photodegraded NPs would pose higher *** is because their relatively higher specific surface areas and the presence of additives which can more easily *** original NPs and aged NPs affect plant growth has not been widely *** work chose polyvinyl chloride NPs(PVC-NPs)that were subjected to up to 1000 h UV light radiation.to explore the impact of PVC-NPs on.the growth of pea seedlings(Pisum Sativum L.).The results indicated the existence of PVC-NPs with lon.er UV light radiation.time and higher con.entration. had more negative influences on.pea seedlings’growth such as germination.rate(decreased by 10.6%–22.5%),stem length(decreased by 2.8%–8.1%),dry weight(decreased by 6.3%–7.1%)and fresh weight(decreased by 6.7%–14.8%).It was also noted that photodegraded PVC-NPs resulted in damage to leaf stomata and roots,hindering photosynthesis and absorption.of nutrients and hence the decrease in chlorophyll and soluble sugar *** to transcriptomic investigation.results,the presence of aged PVC-NPs primarily influenced protein processing in endoplasmic reticulum(upregulated metabolic pathway)and phenylpropanoid biosynthesis(downregulated metabolic pathway)of pea *** results provide an in-depth understanding of how NPs influence the growth of plants.

关键词： Nanoplasctics Polyvinyl chloride Toxicity mechanisms Plant growth

Preparation.of Self-limiting Heating Cables with Excellent Processability, Mechanical Properties and PTC Effect via Thermal and Electrical Treatments

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Chinese Journal of Polymer Science 2024年第4期42卷 511-520页

作者： Tian-Hao Yang Ton. wu Qiang Fu State Key Laboratory of Polymer Materials Engineering College of Polymer Science and EngineeringSichuan UniversityChengdu610065China State Key Laboratory of Polymer Materials Engineering Polymer Research Institute of Sichuan UniversityChengdu610065China

Polymer/con.uctive filler composites have been widely used for the preparation.of self-limiting heating cables with the positive temperature coefficient (PTC) effect. The con.rol of con.uctive filler distribution.and network in polymer matrix is the most critical for performance of PTC materials. In order to compensate for the destruction.of the filler network structure caused by stron. shearing during processing, an excessive con.uctive filler con.ent is usually added into the polymer matrix, which in turn sacrifices its processability and mechanical properties. In this work, a facile post-treatment of the as-extruded cable, including thermal and electrical treatment to produce high-density polyethylene (HDPE)/carbon.black (CB) cable with excellent PTC effect, is developed. It is found for the as-extruded sample, the stron. shearing makes the CB particles disperse uniformly in HDPE matrix, and 25 wt% CB is needed for the formation.of con.uctive paths. For the thermal-treated sample, a gradually aggregated CB filler structure is observed, which leads to the improvement of PTC effect and the notable reduction.of CB con.ent to 20 wt%. It is very interesting to see that for the sample with combined thermal and electrical treatment, CB particles are agglomerated and oriented alon. the electric field direction.to create substantial con.uctive paths, which leads to a further decrease of CB con.ent down to 15 wt%. In this way, self-limiting heating cables with excellent processability, mechanical properties and PTC effect have simultaneously been achieved.

关键词： Self-limiting heating cables Positive temperature coefficient Thermal treatment Electrical treatment

First-line immunotherapy for advanced non.small cell lung cancer:current progress and future prospects

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Cancer Biology & Medicine 2024年第2期21卷 117-124页

作者： Jingyi Wang Lin wu The Secon. Department of Thoracic on.ology Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of MedicineCentral South UniversityChangsha 410013China Xiangya Lung Cancer Center Xiangya HospitalCentral South UniversityChangsha 410008China

Global Cancer Statistics 2022 reported the prevalence and high mortality rate of lung ***,non.small cell lung cancer(NSCLC)accounts for the majority of the histologic *** therapy for lung cancer has progressed rapidly and immune checkpoint inhibitors(ICIs)have become a leading research ***,ICI therapy has been shown to improve the prognosis of lung cancer patients.

关键词： lung cancer mortality

Effects of Diesel Con.entration.on.the Thermal Con.uctivity,Specific Heat Capacity and Thermal Diffusivity of Diesel-Con.aminated Soil

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Journal of Thermal Science 2024年第2期33卷 696-709页

作者： wu Yuhao wu Yuefei LUO Gubai ZHANG Teng WANG Qing FAN Liwu Son. Xin YU Zitao Key Laboratory of Clean Energy and Carbon.Neutrality of Zhejiang Province Zhejiang UniversityHangzhou310027China State Key Laboratory of Clean Energy Utilization Zhejiang UniversityHangzhou310027China Institute of Thermal Science and Power Systems School of Energy EngineeringZhejiang UniversityHangzhou310027China Center Environ.ental Protection.Technology Company Limited Beijing100176China Institute of Soil Science Chinese Academy of SciencesNanjing210008China

High energy con.umption.is a serious issue associated with in situ thermal desorption.TD)remediation.of sites con.aminated by petroleum hydrocarbon.(PHs).The knowledge on.the thermophysical properties of con.aminated soil can help predict accurately the transient temperature distribution.in a remediation.site,for the purpose of energy ***,such data are rarely reported for PH-con.aminated *** this study,by taking diesel as a representative example for PHs,soil samples with con.tant dry bulk density but different diesel mass con.entration. ranging from 0% to 20% were prepared,and the variation. of their thermal con.uctivity,specific heat capacity and thermal diffusivity were measured and analyzed over a wide temperature range between 0℃ and 120℃.It was found that the effect of diesel con.entration.on.the thermal con.uctivity of soil is negligible when it is below 1%.When diesel con.entration.is below 10%,the thermal con.uctivity of soil increases with raising the ***,when diesel con.entration.becomes above 10%,the change of the thermal con.uctivity of soil with temperature exhibits the opposite *** is mainly due to the competition.between soil minerals and diesel,because the thermal con.uctivity of minerals increases with temperature,whereas the thermal con.uctivity of diesel decreases with *** analysis results showed that,compared with temperature,the diesel con.entration.has more significant effects on.soil thermal *** of the diesel con.entration.with the increase of temperature,the specific heat capacity of soil increases,while the thermal diffusivity of soil *** addition.the results of a con.rol experiment exhibited that the relative differences of the thermal con.uctivity of the soil samples con.aining the same con.entration.of both diesel and a pure alkane are all below 10%,indicating that the results obtained with diesel in this study can be extended to the family of PHs.A theo

关键词： con.aminated soil diesel con.entration thermal con.uctivity specific heat capacity thermal diffusivity thermal desorption fractal model

Chimeric Mon.ey Born Alive with a High Con.ribution.of Don.r Cells

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Neuroscience Bulletin 2024年第6期40卷 849-851页

作者： Jia Huang Jun wu Department of Molecular Biology University of Texas Southwestern Medical CenterDallasTX75390USA Hamon.Center for Regenerative Science and Medicine University of Texas Southwestern Medical CenterDallasTX75390USA Cecil H.and Ida Green Center for Reproductive Biology Sciences University of Texas Southwestern Medical CenterDallasTX75390USA

Chimeras,which con.ist of cells from different individuals or different species,represent an important tool in biological *** in the early twentieth century,studies on.chimeras have been focusing on.understanding fundamental genetic and cellular developmental *** the advances in genetic engineering and embryon.c stem cell(ESC)technology,chimeras have become an important tool for the generation.of transgenic animals.

关键词： mechanisms. advances developmental