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How has the COVID-19 pandemic changed treatment preferences of patients with proximal ureteral stones?

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Botulinum Toxin-A for the Treatment of Voiding Dysfunction: Our Initial Experience

当代泌尿学（英文） 2024年第1期18卷 66-70页

作者： Ali Kaan Yildiz Ahmet Varan Hakan kurt omer Gokhan Doluoglu Berat Cem Ozgur Department of Urology University of Medical SciencesAnkara Training and Research HospitalAnkaraTurkey

Background:The impact of the coronavirus disease 2019(COVID-19)pandemic on patient decision making remains *** study aimed to investigate the effect of the pandemic on treatment preferences of patients with proximal ureteral stones.Materials and methods:Retrospective data regarding treatment preferences of patients diagnosed with symptomatic proximal ure-teral stones between July 2018 and November 2021 at a single center were *** from 493 patients were analyzed according to 2 groups,including patients diagnosed during the COVID-19 pandemic and those diagnosed during an equivalent period of time be-fore the pandemic.Results:Preference for conservative treatment increased during the COVID-19 pandemic(p=0.009).In patients who had previously undergone shock wave lithotripsy(SWL),the preference for SWL decreased and the preference for conservative treatment increased during the COVID-19 pandemic(p=0.042).Multiple logistic regression analysis revealed a significant correlation between a preference for conservative treatment during the pandemic and no prior spontaneous stone passage(p=0.003;odds ratio[OR],2.48;95％con-fidence interval[CI],1.45-4.23),no hydronephrosis(p=0.035;OR,3.57;95％Cl,1.34-9.49),and a visual analog scale score of 4 or less(p=0.018;OR,1.97;95％Cl,1.15-3.38).Conclusions:A significant increase in the preference for conservative treatment was observed among patients diagnosed during the pandemic,and patients with a history of SWL demonstrated a preference shift from SWL to conservative treatment.

关键词： COVID-19 pandemic Treatment preference Ureter Urolithiasis.

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Open Journal of Urology 2012年第2期2卷 67-71页

作者： Sinharib Citgez Bulent Onal Fetullah Gevher Cagatay Dogan omer kurt Oktay Demirkesen Bulent Cetinel Department of Urology Cerrahpasa Medical Faculty University of Istanbul Istanbul Turkey

Objective: Evaluation of Botulinum Toxin-A (BTX-A) as an alternative treatment option in patients whom previous treatments were failed. Methods: Between March 2005 and September 2006, a total 19 patients;16 patients with overactive bladder (5 neurologic, 11 idiopathic), 2 with nocturnal enuresis, 1 with interstitial cystitis, intravesical BTX-A injection was applied. Except one patient, 18 patients with a median age 46 (20 - 80) were registered to the study. Patients were examined at postoperative 3 weeks and 6 months with ICIQ-SF (International Consultation on Incontinence Questionnaire-Short Form) and satisfaction forms used in our clinic. Results: The median follow-up time was 16 months (6 - 18). When evaluated according to diagnosis, symptoms were improved 100% in neurologic overactive bladder (5/5), 80% in idiopathic overactivity (8/10), 50% in nocturnal enuresis (1/2). In one patient with interstitial cystitis there was no improvement. Median efficiency time of BTX-A treatment was 6 months (1 - 17). At 3 weeks and 6 months after the treatment, ICIQ-SF score was decreased to 3.6 and 7.5 respectively from preoperative level of 18.7. Quality of life scores at preoperative, 3 week and 6 months were 9.7, 2.7 and 4.3 respectively. Except 3 patients with overactive neurologic bladder because of spinal cord injury, symptoms of patients with pollacuria and nocturia decreased at 3. week. Even if these rates increased at 6 months they still were significantly less than preoperative status. The spinal cord injured 3 patients had clean intermittent catheterization per 1 hour and had urinary incontinence between the catheterizations preoperatively, however at 3 weeks and 6 months the intervals of catheterisations was 4 hours and 3 hours respectively and also the urinary incontinance between the catheterisations improved. At patient satisfactions, 78% of patients declared that they were pleased and underwent the procedure again and will recommend it to their relatives with s

关键词： Botulinum Toksin-A Overactive Bladder Voiding Dysfunction

Solution approximations for a mathematical model of relativistic electrons with beta derivative

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Applied Mathematics(A Journal of Chinese Universities) 2024年第3期39卷 469-485页

作者： Ibrahim Yalcinkaya Orkun Tasbozan Ali kurt Hijaz Ahmad Department of Mathematics and Computer Sciences Faculty of ScienceNecmettin Erbakan UniversityKonyaTurkey Department of Mathematics Faculty of Science and LiteratureHatay Mustafa Kemal UniversityHatayTurkey Department of Mathematics Faculty of SciencePamukkale UniversityDenizliTurkey Near East University Operational Research Center in HealthcareTRNC Mersin 10Nicosia99138Turkey Department of Mathematics Faculty of ScienceIslamic University of MadinahMadinahSaudi Arabia

The main aim of this paper is to obtain the exact and semi-analytical solutions of the nonlinear Klein-Fock-Gordon(KFG)equation which is a model of relativistic electrons arising in the laser thermonuclear fusion with beta *** this purpose,both the modified extended tanh-function(mETF)method and the homotopy analysis method(HAM)are *** applying the mETF the chain rule for beta derivative and complex wave transform are used for obtaining the exact *** advantage of this procedure is that discretization or normalization is not *** applying the mETF,the exact solutions are ***,by applying the HAM semi-analytical results for the considered equation are *** HAM?curve gives us a chance to find the suitable value of the for the convergence of the solution ***,comparative graphical representations are given to show the effectiveness,reliability of the *** results show that the m ETF and HAM are reliable and applicable tools for obtaining the solutions of non-linear fractional partial differential equations that involve beta *** study can bring a new perspective for studies on fractional differential *** the other hand,it can be said that scientists can apply the considered methods for different mathematical models arising in physics,chemistry,engineering,social sciences and *** involves fractional *** the results may cause a new insight who studies on relativistic electron modelling.

关键词： Klein-Fock-Gordon(KFG)equation beta derivative semi-analytical solution exact solution

Red cell distribution width itself without other inflammatory markers may not accurately provide information about severity of coronary artery disease

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Chinese Medical Journal 2013年第16期126卷 3190-3190页

作者： Sevket Balta Sait Demirkol Mustafa Cakar Mustafa Dinc omer kurt Hakan Sarlak Department of Cardiology Gulhane Medical Academy Ankara Turkey Department of Internal Medicine Gulhane Medical Academy Ankara Turkey

To the editor：We read the article by Ma et al1 with a great *** aimed to investigate the potential correlation of red cell distribution width （RDW） with the severity of coronary artery disease （CAD） in a large Chinese cohort from a single *** concluded that the RDW level was significantly higher in patients with CAD than that in normal controls,and the baseline RDW level was an independent predictor for CAD and the severity of coronary stenosis.

关键词： distribution inflammatory disease

The replication crisis and its relevance to Earth Science studies:Case studies and recommendations

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Geoscience Frontiers 2024年第4期15卷 304-314页

作者： Stephen J.Puetz Kent C.Condie kurt Sundell Nick M.W.Roberts Christopher J.Spencer Slah Boulila Qiuming Cheng 475 Atkinson Dr Suite 704HonoluluHI 96814USA New Mexico Institute of Mining and Technology SocorroNM 87801USA Idaho State University PocatelloID 83209USA Geochronology and Tracers Facility British Geological SurveyKeyworthNottingham NG125GGUK Queen’s University Department of Geological Sciences and Geological EngineeringKingstonOntario K7L 3N6Canada Sorbonne Université CNRSInstitut des Sciences de la Terre ParisParisFrance State Key Laboratory of Geological Processes and Mineral Resources China University of GeosciencesWuhan 430074China

Numerous scientific fields are facing a replication crisis,where the results of a study often cannot be replicated when a new study uses independent *** issue has been particularly emphasized in psychology,health,and medicine,as incorrect results in these fields could have serious consequences,where lives might be at *** other fields have also highlighted significant replication problems,the Earth Sciences seem to be an *** paucity of Earth Science research aimed at understanding the replication crisis prompted this ***,this work aims to fill that gap by seeking to replicate geological results involving various types of *** identify and discuss 11 key variables for replicating U-Pb age distributions:independent data,global sampling,proxy data,data quality,disproportionate non-random sampling,stratigraphic bias,potential filtering bias,accuracy and precision,correlating time-series segments,testing assumptions and divergent analytical methods,and analytical *** while this work primarily focuses on U-Pb age distributions,most of these factors(or variations of them)also apply to other geoscience ***,some of the discussions involve time-series consisting ofεHf,δ18O-zircon,14C,10Be,marineδ13C,and marineδ*** then provide specific recommendations for minimizing adverse effects related to these factors,and in the process enhancing prospects for replicating geological results.

关键词： Replication crisis Replicability Independent data Global time-series Globality index Filtered data

Fetal lung growth predicts the risk for early-life respiratory infections and childhood asthma

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World Journal of Pediatrics 2024年第5期20卷 481-495页

作者： Dimitra E.Zazara Olympia Giannou Steven Schepanski Mirja Pagenkemper Anastasios D.Giannou Maike Pincus Ioannis Belios Stefan Bonn Ania C.Muntau kurt Hecher Anke Diemert Petra Clara Arck Division for Experimental Feto-Maternal Medicine Department of Obstetrics and Fetal MedicineUniversity Medical Center Hamburg-Eppendorf(UKE)Martinistraße 5220251HamburgGermany University Children’s Hospital UKEHamburgGermany Computer Engineering and Informatics Department Polytechnic SchoolUniversity of PatrasPatrasGreece Institute of Developmental Neurophysiology Center for Molecular Neurobiology Hamburg(ZMNH)UKEHamburgGermany Department of Obstetrics and Fetal Medicine UKEHamburgGermany Department of General Visceral and Thoracic SurgeryUKEHamburgGermany Section of Molecular Immunology and Gastroenterology Ⅰ.Department of MedicineUKEHamburgGermany Pediatrics and Pediatric Pneumology Practice BerlinGermany Institute of Medical Systems Biology ZMNHUKEHamburgGermany Hamburg Center for Translational Immunology UKEHamburgGermany

Background Early-life respiratory infections and asthma are major health burdens during *** predicting an increased risk for early-life respiratory diseases are ***,we identified the predictive value of ultrasound-monitored fetal lung growth for the risk of early-life respiratory infections and *** Fetal lung size was serially assessed at standardized time points by transabdominal ultrasound in pregnant women participating in a pregnancy *** between fetal lung growth and respiratory infections in infancy or early-onset asthma at five years were ***-learning models relying on extreme gradient boosting regressor or classifier algorithms were developed to predict respiratory infection or asthma risk based on fetal lung *** model development and validation,study participants were randomly divided into a training and a testing group,respectively,by the employed *** Enhanced fetal lung growth throughout pregnancy predicted a lower early-life respiratory infection *** sex was associated with a higher risk for respiratory infections in *** lung growth could also predict the risk of asthma at five years of *** designed three machine-learning models to predict the risk and number of infections in infancy as well as the risk of early-onset *** models’R2 values were 0.92,0.90 and 0.93,respectively,underscoring a high accuracy and agreement between the actual and predicted *** variables included known risk factors and novel predictors,such as ultrasound-monitored fetal lung *** Sonographic monitoring of fetal lung growth allows to predict the risk for early-life respiratory infections and asthma.

关键词： Asthma Child risk Early-life respiratory infections Prenatal lung development Sexual dimorphism

Analysis of a New Toothbrushing Technique through Plaque Removal Success

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Open Journal of Stomatology 2024年第3期14卷 133-152页

作者： Elhadi A. A. Shkorfu Serkan kurt Fatih Atalar Ali Olamat Aysel Ersoy Department of Electrical and Electronic Engineering Istanbul University-Cerrahpa&scedila Avc&imathlar Istanbul Türkiye Department of Electronics and Communication Engineering Y&imathld&imathz Technical University Istanbul Türkiye Department of Bioengineering Y&imathld&imathz Technical University Istanbul Türkiye

Background/Aims: Determining the levels of oral health and the quality of dental care are fundamental to building concepts of oral health. This study aims to assess toothbrushing techniques using a technical and physical model, clarifying how children and pre-adults learn to brush their teeth. Materials and Methods: Data were recorded from 23 participants, both male and female of various ages, using a proposed electronic toothbrush equipped with X-Y-Z axes pathways. The data, collected before and after training experiments, were processed with MATLAB to generate plots for the three axes. Results: The study revealed that most parameter values, such as Mean Difference Between Amplitudes (MAV, 6.00), Wilson Amplitude (WAMP, 179.419), and Average Amplitude Coupling (AAC, 1.270), decreased from before to after the experiments. Furthermore, the average overall epoch lengths (AVG) showed a 75% reduction in movement amplitude between the two experiments. Conclusion: Dentist observations indicated which brushing methods were acceptable or not. Analytical values suggest that individuals learn the toothbrushing technique effectively, and medical observations clearly demonstrate the success of the proposed method.

关键词： Techno-Physical Toothbrushing Oral Hygiene Education Dental Technology Plaque Analysis

Threads拟推广服务加剧与X的商业竞争

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商业周刊（中文版） 2024年第11期 12-13页

作者： kurt Wagner 程玺(译) 不详

对阵X一周年后,Threads已网罗1.75亿月活用户下一步是与X争夺广告收入。一年前,当埃隆·马斯克(Elon Musk)的社交媒体平台X(旧称推特)深陷困境之时,Meta PlatformsInc.的马克·扎克伯格(Mark Zuckerberg)把握时机推出了Threads。

关键词：把握时机广告收入推广服务商业竞争社交媒体平台

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应对政治风暴Meta做出中立承诺

商业周刊（中文版） 2024年第14期 51-52页

作者： kurt Wagner Emily Chang 陈佳靖不详

近年来,Meta一直在逐步淡化政治氛围,面对即将举行的美国总统大选,身为CEO的扎克伯格极力表现出无党派倾向,随着2024年美国大选临近,社交媒体再度陷入可能干预选举的巨大争议之中,Meta也不例外。美国共和党总统候选人、前总统唐纳德·... 详细信息

近年来,Meta一直在逐步淡化政治氛围,面对即将举行的美国总统大选,身为CEO的扎克伯格极力表现出无党派倾向,随着2024年美国大选临近,社交媒体再度陷入可能干预选举的巨大争议之中,Meta也不例外。美国共和党总统候选人、前总统唐纳德·特朗普(Donald Trump)在9月出版的新书中声称,Meta首席执行官马克·扎克伯格在2020年美国总统选举期间曾密谋阻挠他当选。特朗普还放下狠话称,如果再次这么做,扎克伯格“将在监狱中度过余生”。这是特朗普对扎克伯格的最新攻击,这位前总统曾多次秤击对方干预了上届大选。

关键词：美国总统选举美国总统大选总统候选人特朗普美国大选社交媒体美国共和党淡化政治