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Botulinum Toxin-A for the Treatment of Voiding Dysfunction: Our Initial Experience

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Open Journal of Urology 2012年第2期2卷 67-71页

作者： Sinharib Citgez Bulent Onal Fetullah Gevher Cagatay Dogan omer kurt Oktay Demirkesen Bulent Cetinel Department of Urology Cerrahpasa Medical Faculty University of Istanbul Istanbul Turkey

Objective: Evaluation of Botulinum Toxin-A (BTX-A) as an alternative treatment option in patients whom previous treatments were failed. Methods: Between March 2005 and September 2006, a total 19 patients;16 patients with overactive bladder (5 neurologic, 11 idiopathic), 2 with nocturnal enuresis, 1 with interstitial cystitis, intravesical BTX-A injection was applied. Except one patient, 18 patients with a median age 46 (20 - 80) were registered to the study. Patients were examined at postoperative 3 weeks and 6 months with ICIQ-SF (International Consultation on Incontinence Questionnaire-Short Form) and satisfaction forms used in our clinic. Results: The median follow-up time was 16 months (6 - 18). When evaluated according to diagnosis, symptoms were improved 100% in neurologic overactive bladder (5/5), 80% in idiopathic overactivity (8/10), 50% in nocturnal enuresis (1/2). In one patient with interstitial cystitis there was no improvement. Median efficiency time of BTX-A treatment was 6 months (1 - 17). At 3 weeks and 6 months after the treatment, ICIQ-SF score was decreased to 3.6 and 7.5 respectively from preoperative level of 18.7. Quality of life scores at preoperative, 3 week and 6 months were 9.7, 2.7 and 4.3 respectively. Except 3 patients with overactive neurologic bladder because of spinal cord injury, symptoms of patients with pollacuria and nocturia decreased at 3. week. Even if these rates increased at 6 months they still were significantly less than preoperative status. The spinal cord injured 3 patients had clean intermittent catheterization per 1 hour and had urinary incontinence between the catheterizations preoperatively, however at 3 weeks and 6 months the intervals of catheterisations was 4 hours and 3 hours respectively and also the urinary incontinance between the catheterisations improved. At patient satisfactions, 78% of patients declared that they were pleased and underwent the procedure again and will recommend it to their relatives with s

关键词： Botulinum Toksin-A Overactive Bladder Voiding Dysfunction

Red cell distribution width itself without other inflammatory markers may not accurately provide information about severity of coronary artery disease

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Chinese Medical Journal 2013年第16期126卷 3190-3190页

作者： Sevket Balta Sait Demirkol Mustafa Cakar Mustafa Dinc omer kurt Hakan Sarlak Department of Cardiology Gulhane Medical Academy Ankara Turkey Department of Internal Medicine Gulhane Medical Academy Ankara Turkey

To the editor：We read the article by Ma et al1 with a great *** aimed to investigate the potential correlation of red cell distribution width （RDW） with the severity of coronary artery disease （CAD） in a large Chinese cohort from a single *** concluded that the RDW level was significantly higher in patients with CAD than that in normal controls,and the baseline RDW level was an independent predictor for CAD and the severity of coronary stenosis.

关键词： distribution inflammatory disease

Effects of contrast media on the hepato-pancreato-biliary system

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World Journal of Gastroenterology 2009年第38期15卷 4788-4793页

作者： omer Topcu Atilla kurt Isilay Nadir Sema Arici Ayhan Koyuncu Cengiz Aydin Department of General Surgery Faculty of MedicineCumhuriyet University Department of Gastroenterology Numune Hospital Department of Pathology Faculty of MedicineCumhuriyet University

AIM： To determine the effects of high osmolarity contrast media （HOCM） and iso-osmolar contrast media （CM） application, with or without pressure, on hepato-pancreato-biliary （HPB） system. METHODS： Sixty rats were divided into six equal groups as follows： Group i：（0.9% NaCl, control）, Group 2：（diatrizoate meglumine Na, ionic HOCM, Urographin）, Group 3：（iodixanol, iso-osmolar nonionic CM, Visipaque）; each of which was applied without pressure, whereas the animals of the remaining three groups （1p, 2p, 3p） were subjected to the same CM with pressure. We performed a duodenal puncture and introduced a catheter into the ampulla. After the catheterization, 0.2 mL CM or 0.9% NaCI was injected with or without pressure. Blood samples were taken for biochemical evaluations. The histopathological examinations of liver, common bile duct, and pancreas were performed. RESULTS： There were no significant differences between the six groups for blood amylase, alanine aminotransferases, aspartate aminotransferases, bilirubin levels （P 〉 0.05）. Alkaline phosphatase and γ glutamyl transaminase levels were higher （P 〈 0.05） in the Urographin groups （2, 2p） than the Visipaque groups （3, 3p）, or control groups （1, 1p）. Hepatocyte necrosis, portal area inflammation, and Kupffer＇s cell hyperplasia were higher （P 〈 0.05） in the study groups than the control group. However, there were no significant differences （P 〉 0.05） between HOCM （2, 2p） and iso-osmolar CM （3, 3p） groups. Bile duct proliferation and regeneration in the Urographin groups （2, 2p） were significantly higher （P 〈 0.05） than the Visipaque~ groups （3, 3p） or the control groups （1, lp）. Although CM caused minor damage to the pancreas, there were no statistically significant differences （P 〉 0.05） between the groups. Application of the CM with pressure did not cause additional damage to the HPB system. CONCLUSION： Iso-osmolar, non-ionic CM could be more reliable than the ionic HOCM, whereas the application of pressure during the

关键词： Contrast media Liver Pancreas Biliarytract Pressure

Calculation of the infrared frequency and the damping constant (full width at half maximum) for metal organic frameworks

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Chinese Physics B 2019年第6期28卷 324-331页

作者： M kurt H Yurtseven A kurt S Aksoy Department of Physics Canakkale 18 Mart University17100 CanakkaleTurkey Department of Physics Middle East Technical University06531 AnkaraTurkey Lapseki ICDAS CIB MTAL High School 17100 CanakkaleTurkey

The ρ(NH2) infrared(IR) frequencies and the corresponding full width at half maximum(FWHM) values for(CH3)2 NH2 FeⅢ M Ⅱ(HCOO)6(DMFe M, M = Ni, Zn, Cu, Fe, and Mg) are analyzed at various temperatures by using the experimental data from the literature. For the analysis of the IR frequencies of the ρ(NH2) mode which is associated with the structural phase transitions in those metal structures, the temperature dependence of the mode frequency is assumed as an order parameter and the IR frequencies are calculated by using the molecular field theory. Also, the temperature dependence of the IR frequencies and of the damping constant as calculated from the models of pseudospin(dynamic disorder of dimethylammonium(DMA+) cations)–phonon coupling(PS) and of the energy fluctuation(EF), is fitted to the observed data for the wavenumber and FWHM of the ρ(NH2) IR mode of the niccolites studied here. We find that the observed behavior of the IR frequencies and the FWHM of this mode can be described adequately by the models studied for the crystalline structures of interest. This method of calculating the frequencies(IR and Raman) and FWHM of modes which are responsible for the phase transitions can also be applied to some other metal organic frameworks.

关键词： infrared(IR) frequency full width at half maximum(FWHM) phase transitions ρ(NH2) mode niccolites

How has the COVID-19 pandemic changed treatment preferences of patients with proximal ureteral stones?

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Current Urology 2024年第1期18卷 66-70页

作者： Ali Kaan Yildiz Ahmet Varan Hakan kurt omer Gokhan Doluoglu Berat Cem Ozgur Department of Urology University of Medical SciencesAnkara Training and Research HospitalAnkaraTurkey

Background:The impact of the coronavirus disease 2019(COVID-19)pandemic on patient decision making remains *** study aimed to investigate the effect of the pandemic on treatment preferences of patients with proximal ureteral *** and methods:Retrospective data regarding treatment preferences of patients diagnosed with symptomatic proximal ureteral stones between July 2018 and November 2021 at a single center were *** from 493 patients were analyzed according to 2 groups,including patients diagnosed during the COVID-19 pandemic and those diagnosed during an equivalent period of time before the ***:Preference for conservative treatment increased during the COVID-19 pandemic(p=0.009).In patients who had previously undergone shock wave lithotripsy(SWL),the preference for SWL decreased and the preference for conservative treatment increased during the COVID-19 pandemic(p=0.042).Multiple logistic regression analysis revealed a significant correlation between a preference for conservative treatment during the pandemic and no prior spontaneous stone passage(p=0.003;odds ratio[OR],2.48;95%confidence interval[CI],1.45-4.23),no hydronephrosis(p=0.035;OR,3.57;95%Cl,1.34-9.49),and a visual analog scale score of 4 or less(p=0.018;OR,1.97;95%Cl,1.15-3.38).Conclusions:A significant increase in the preference for conservative treatment was observed among patients diagnosed during the pandemic,and patients with a history of SWL demonstrated a preference shift from SWL to conservative treatment.

关键词： COVID-19 pandemic Treatment preference Ureter Urolithiasis

New Analytical and Numerical Results For Fractional Bogoyavlensky-Konopelchenko Equation Arising in Fluid Dynamics

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Applied Mathematics(A Journal of Chinese Universities) 2020年第1期35卷 101-112页

作者： Ali kurt Department of Mathematics Pamukkale UniversityDenizli 20180Turkey

In this article,(2+1)-dimensional time fractional Bogoyavlensky-Konopelchenko(BK)equation is studied,which describes the interaction of wave propagating along the x axis and y *** acquire the exact solutions of BK equation we employed sub equation method that is predicated on Riccati equation,and for numerical solutions the residual power series method is *** graphical results that compares the numerical and analytical solutions are given for di erent values of.Also comparative table for the obtained solutions is presented.

关键词： Conformable Fractional Derivative Fractional Bogoyavlensky-Konopelchenko Equation Sub-Equation Method Residual Power Series Method

Exploration of the Townsend regime by discharge light emission in a gas discharge device

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Chinese Physics B 2014年第1期23卷 289-296页

作者： Hilal Yucel kurt Gazi University Faculty of Sciences Department of Physics 06500 Ankara Turkey

The Townsend discharge mechanism has been explored in a planar microelectronic gas discharge device （MGDD） with different applied voltages U and interelectrode distance d under various pressures in air. The anode and the cathode of the MGDD are formed by a transparent SnO2 covered glass and a GaAs semiconductor, respectively. In the experiments, the discharge is found to be unstable just below the breakdown voltage Ub, whereas the discharge passes through a homo- geneous stable Townsend mode beyond the breakdown voltage. The measurements are made by an electrical circuit and a CCD camera by recording the currents and light emission （LE） intensities. The intensity profiles, which are converted from the 3D light emission images along the semiconductor diameter, have been analysed for different system parameters. Dif- ferent instantaneous conductivity ~t regimes are found below and beyond the Townsend region. These regimes govern the current and spatio-temporal LE stabilities in the plasma system. It has been proven that the stable LE region increases up to 550 Torr as a function of pressure for small d. If the active area of the semiconductor becomes larger and the interlectrode distance d becomes smaller, the stable LE region stays nearly constant with pressure.

关键词： Townsend discharge breakdown microelectronic gas discharge device semiconductor cathode

Effect of ZrSiO_4 on the Friction Performance of Automotive Brake Friction Materials

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Journal of Materials Science & Technology 2007年第6期23卷 843-850页

作者： Mustafa BOZ Adem kurt Metallurgy Department Z.K.U.Karabük Technical Education Faculty78200 KarabükTurkey Metallurgy Department Gazi UniversityTechnical Education Faculty06500 AnkaraTurkey

Friction-wear properties of the ZrSiO4 reinforced samples were measured and compared with those of plain bronze based ones. For this purpose, density, hardness, friction coefficient wear behaviour of the samples were tested. Microstructures of samples before and after sintering and worn surfaces were also investigated by scanning electron microscopy （SEM）, and the wear types were determined. The optimum friction-wear behaviour was obtained in the sample compacted at 500 MPa and sintered at 820℃. Density of the final samples decreased with increasing the amount of reinforcing elements （ZrSiO4） before pre-sintering. However after sintering, there is no change in density of the samples including reinforcing elements （ZrSiO4）. With increasing friction surface temperature, a reduction in the friction coefficient of the samples was observed. However, the highest reductions in the friction coefficients were observed in the as-received samples containing 0. 5% reinforced ZrSiO4. The SEM images of the sample indicated that while bronze-based break lining material without ZrSiO4 showed abrasive wear behaviour, increasing the amount of ZrSiO4 resulted a change in abrasive to adhesive wear mechanism. All samples exhibited friction-wear values, which were within the values shown in SAE-J661 standard. With increasing the amount of reinforcing ZrSiO4, wear resistance of the samples was increased. However samples reinforced with 5% and 6% ZrSiO4 showed the best results.

关键词： Friction materials ZrSiO4 Wear Friction Brake lining

Effect of Different Amounts of Graphite on the Sintering and Transverse Rupture Properties of Powder Metal Parts

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Journal of Materials Science & Technology 2006年第3期22卷 419-422页

作者： Mustafa Boz Adem kurt Karabuk Technical Education Faculty Zonguldak Karaelmas University Karabuk 78050 Turkey Technical Education Faculty Gazi University Besevler 06500 Ankara Turkey

Iron powders were mixed with graphite powders by 1-15 wt pct to produce block samples using powder metallurgy technique. The powders were blended in a three dimensional blender for 20 min and compacted in a die under 500 MPa by using a one directional press. Sinterability and mechanical properties of the samples with different carbon content were investigated. Sintering process was carried out on a belt furnace with flame curtain in dissociated ammonia atmosphere. Block samples produced were suitable for ASTM B-312 transverse rupture strength test apparatus and were tested with 0.050 kN/s velocity in a press under 100 g load. It was found that graphite amount up to 2 wt pct increased the contact area of particles and acted as a lubricant to affect the sintering behaviour positively. The results indicated that the samples containing up to 5 wt pct showed good sintering behaviour and also good hardness due to an increase in pearlite amount. However, the samples containing higher amount of graphite （more than 5 wt pct） affected the sintering behaviour negatively due to the settlement of free graphite around the Fe powders, which resulted in a decrease in the hardness and transverse rupture strength.

关键词： Powder metallurgy Sintering Fe Graphite Transverse rupture strength