检索结果-南通市图书馆

Surgical Science 2018年第1期9卷 52-61页

作者： Waleed Elnahas omar hamdy Khaled Abdel Wahab Sameh Roshdy Sara Raafat Mohamed Hafez omar Farouk Mohamed Elmetwally Surgical Oncology Unit Mansoura Oncology Centre Mansoura University Mansoura Egypt Pathology Department Faculty of Medicine Mansoura University Mansoura Egypt

Purpose: Most important factor affecting prognosis of breast cancer is axillary nodal involvement. Several studies evaluated the accuracy of Sentinel lymph node biopsy in breast cancer patients post neoadjuvant chemotherapy. In this study, we will examine accuracy and feasibility of using Sentinel lymph node biopsy in predicting axillary lymph node status in breast cancer patients after neoadjuvant chemotherapy. Methods: 45 female patients with resectable, nonmetastatic breast carcinoma cases who received neoadjuvant chemotherapy were enrolled in this study according to the routine Mansoura Oncology Center—guidelines of management of breast cancer. Methylene blue dye used for detection of Sentinel lymph node. Results: Successful Sentinel lymph node detection was 82.2%. Skin involvement (T4 disease) were linked to a low identification (P = 0.005). False negative rate equals 11/27 = (40.7%).With advancement of the stage of the tumor, the incidence of false negative results increases significantly (p = 0.012) with 95% confidence interval;1.2 - 5.4. Conclusion: Sentinel lymph node should be adopted to be the standard method for axillary staging with T1-3 tumors after receiving neoadjuvant chemotherapy, in T4 patients, it is associated with low detection rate & high false negative rate making it doubtful technique for axillary staging.

关键词： Breast Cancer Sentinel Lymph Node Neo Adjuvant Chemotherapy Blue Dye

Evaluation of Bilateral Mental Nerve Block as an Alternative to General Anesthesia for Resection of Lower Lip Tumors

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Surgical Science 2017年第8期8卷 319-325页

作者： Ashraf Khater Islam A. Elzahaby Mohamed hamdy Mohammad Zuhdy omar hamdy Mohamed Ezzat Mahmoud Abdelaziz Ahmad M. Farid Mansour Elmoatasem Amr Hassan Khalid Atallah Mahmoud Mostafa Saleh Maha A. Abo-Zeid Amr Yassin Ola Taha Abd Eldayem Mona Gad Department of Surgical Oncology Mansoura Oncology Center (OCMU) Faculty of Medicine Mansoura University Mansoura Egypt Anesthesia and Surgical Intensive Care Department Mansoura University Hospital Faculty of Medicine Mansoura University Mansoura Egypt

Objective: Nerve blockade is commonly used in oncosurgical procedures as an alternative to general anesthesia for older patients and those with significant medical problems. We report a single tertiary oncology center experience in performing various lip resections and reconstructive techniques using this technique. Patients and methods: sixty patients with lower lip tumors were enrolled into this study with exclusion of refusing, non-compliant and critically ill patients. A solution of 4 ml 2% Lidocaine and epinephrine was put in a 5 ml syringe. Half the solution (2 ml) was injected into each side with a 23 gauge needle and after 5 minutes the surgical resection was carried out after testing for anesthesia. Results: The mean age was 68 ± 6.2 years. The mean ASA score was 3 ± 0.75. There were 4 cases who expressed painful sensation and their operations were completed with fentanyl increments. Mean hospital stay was 1 ± 0.75 days. There were three cases of wound gaping who were treated with secondary closure in an outpatient basis. One patient expressed postoperative acute ischemic heart pain that was managed with anti-ischemic measurements. Conclusion: Bilateral mental nerve block is a safe and effective alternative to general anesthesia in lower lip tumors’ resection especially in older patients and those with poor tolerance for general anesthesia provided that there is no need for cervical nodal dissection.

关键词： Mental Nerve Block Lip Tumors Lidocaine

The Effectiveness of Intraoperative Frozen Section Analysis of Safety Margins in Breast Conserving Surgery and the Role of Surgeon in Decreasing the Rate of Positive Margins

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Surgical Science 2017年第12期8卷 499-509页

作者： omar Farouk Ahmed Senbel Mosab Shetiwy Essam Attia Ahmed Abdallah Osama El-Damshety Ashraf Khater Sameh Roshdy Amr Abouzid Amr Hossam Islam H. Metwally omar hamdy Amir M. Zaid Mahmoud Abdelaziz Mohamed Elmetwally Adel Fathi Emad-Eldeen Hamed Khaled Abdel Wahab Wagdi El-Kashef Mohamed Hafez Khaled Zalata Mohamed Hegazy Adel Denewer Surgical Oncology Department Oncology Center Faculty of Medicine Mansoura University Mansoura Egypt Pathology Department Faculty of Medicine Mansoura University Mansoura Egypt

Introduction: Nowadays the more accepted surgical option for treating early breast cancer is breast conserving surgery. The main challenge in this type of surgery is to get free safety margins without need of second surgical operation, so many breast surgeons have started to depend on intraoperative frozen sections to ensure free safety margins. Aim of work: To assess our policy that we prefer to depend on intraoperative frozen section analysis to get free safety margin in breast conserving surgery from the 1st surgery, and its oncologic outcome. Patients and Methods: This is a retrospective study conducted in Oncology Center—Mansoura University (OCMU), where the data of 219 patients with breast cancer, who were managed by breast conserving surgery with intraoperative frozen section analysis of the safety margins, was analyzed. Results: The intraoperative frozen section analysis of safety margin was negative from the start in 183 (83.6%) patients, while it was positive in 36 patients (16.4%). Intraoperative decision of margin re-excision was applied for 29 patients (13.2%) in order to reach negative margin, modified radical mastectomy was offered for 4 patients (1.8%), while nipple sparing mastectomy with immediate breast reconstruction using latissimus dorsi flap was offered for 3 patients (1.4%). The postoperative paraffin results were typical with intraoperative frozen section analysis results in 216 patients (98.6%) and different results were obtained in only 3 patients (1.4%) who were managed by modified radical mastectomy in a second operation. Only 4 patients had local recurrence (1.8%) during the period of follow-up duration which was ranged from 1 to 86 months with mean ± SD (22.3 ± 14.1). Conclusion: The intraoperative frozen section analysis of safety margins in breast conserving surgery has very high-rate typical results with the paraffin section analysis and it is very helpful in decreasing the rate of second surgical operation in cases of infiltrated m

关键词： Breast Conserving Surgery Intraoperative Frozen Section Analysis Safety Margins Breast

White Cord Syndrome: The Terrible Nightmare

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Modern Neurosurgery 2020年第2期10卷 275-283页

作者： Hussein Fathalla omar Ragab Ahmed hamdy Ashry Division of Neurosurgery Cairo University Hospitals Cairo Egypt Division of Neurosurgery Beni Suef University Beni Suef Egypt

Introduction: Reperfusion injury of spinal cord “white cord syndrome” refers to acute neurological deterioration after decompressive spinal surgery without any reported intraoperative events. The postoperative appearance of diffuse hyperintense intramedullary areas in T2-weighted MRI is characteristic without any other pathological or compressive signs. The etiology may be due to sudden expansion of the cord after reperfusion of chronically ischemic areas leading to disruption of blood-spinal cord barrier. The incidence and risk factors of the syndrome are not well documented in the literature. Methods: This is a retrospective case series that included 150 patients with cervical spondylotic myelopathy who had undergone decompression surgery in our institution from 2017 to 2019. Patients’ demographics, clinical, imaging characteristics, intraoperative and postoperative data were collected and analysed. Results: In this study, we documented 7 cases of this syndrome. We found that advanced age, chronic hypertension, pre-existing cord signal in MRI and long history of symptoms may be risk factors for this syndrome. Conclusion: Early diagnosis and prompt treatment of this syndrome with steroids and physical therapy may lead to initial improvement. Awareness of the surgeons about this syndrome should be increased and identifying its risk factors is very important for patients counseling.

关键词： White Cord Syndrome Spondylotic Cervical Myelopathy Reperfusion Injury

Towards hepatitis C virus elimination:Egyptian experience,achievements and limitations

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2018年第38期24卷 4330-4340页

作者： Dalia Omran Mohamed Alboraie Rania A Zayed Mohamed-Naguib Wifi Mervat Naguib Mohamed Eltabbakh Mohamed Abdellah Ahmed Fouad Sherief Sahar Maklad Heba hamdy Eldemellawy omar Khalid Saad Doaa Mohamed Khamiss Mohamed El Kassas Department of Endemic Medicine and Hepatology Faculty of MedicineCairo UniversityCairo 11651Egypt Department of Endemic Medicine Faculty of MedicineHelwan UniversityCairo 11599Egypt Department of Internal Medicine Al-Azhar UniversityCairo 11651Egypt Department of Clinical and Chemical Pathology Faculty of MedicineCairo UniversityCairo 11651Egypt Department of Internal Medicine Faculty of MedicineCairo UniversityCairo 11599Egypt Department of Tropical Medicine Faculty of MedicineAin Shams UniversityCairo 11566Egypt National Hepatology and Tropical Medicine Research Institute Cairo 11599Egypt Department of Internal Medicine Faculty of MedicineBeni-Suef UniversityBeni-Suef 62511Egypt Faculty of Medicine Ain Shams UniversityCairo 11566Egypt Department of Clinical and Chemical Pathology El-monera hospitalMinistry of HealthCairo 11562Egypt

Worldwide, more than one million people die each year from hepatitis C virus(HCV) related diseases, and over 300 million people are chronically infected with hepatitis B or C. Egypt used to be on the top of the countries with heavy HCV burden. Some countries are making advances in elimination of HCV, yet multiple factors preventing progress; remain for the majority. These factors include lack of global funding sources for treatment, late diagnosis, poor data, and inadequate screening. Treatment of HCV in Egypt has become one of the top national priorities since 2007. Egypt started a national treatment program intending to provide cure for Egyptian HCV-infected patients. Mass HCV treatment program had started using Pegylated interferon and ribavirin between 2007 and 2014. Yet, with the development of highly-effective direct acting antivirals(DAAs) for HCV, elimination of viral hepatitis has become a real possibility. The Egyptian National Committee for the Control of Viral Hepatitis did its best to provide Egyptian HCV patients with DAAs. Egypt adopted a strategy that represents a model of care that could help other countries with high HCV prevalence rate in their battle against HCV. This review covers the effects of HCV management in Egyptian real life settings and the outcome of different treatment protocols. Also, it deals with the current and future strategies for HCV prevention and screening as well as the challenges facing HCV elimination and the prospect of future eradication of HCV.

关键词： Hepatitis C virus Egypt Direct acting antivirals screening elimination Limitations

Effect of SARS-CoV-2 infection on the liver

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Virology 2023年第2期12卷 109-121页

作者： Adekunle Sanyaolu Aleksandra Marinkovic Abu Fahad Abbasi Stephanie Prakash Risha Patidar Priyank Desai Martina Williams Abdul Jan Kareem hamdy Rachael Solomon Vyshnavy Balendra Maaz Ansari omar Shazley Nasar Khan Rochelle Annan Yashika Dixon Chuku Okorie Afolabi Antonio Department of Public Health Federal Ministry of HealthAbujaNigeriaAbuja 0000FCTNigeria Department of Basic Medical Science Saint James School of MedicineThe Quarter 26400000Anguilla Department of Internal Medicine Loyola University Medical CenterMaywoodIllinoisIL 60153United States Department of Basic Medical Science American University of Saint Vincent School of MedicineSaint Vincent and the Grenadines 0000Saint Vincent and the Grenadines Department of Basic Medical Science Windsor University School of MedicineCayon 0000Saint Kitts and Nevis Department of Basic Medical Science Caribbean Medical University School of MedicineWillemstad 0000CuraçaoNetherlands Antilles Basic Medical Science Saint James School of MedicineSaint Vincent and the Grenadines 0000Saint Vincent and the Grenadines University of Health Sciences Antigua School of Medicine PiccadillySt.John's Antigua Department of Science Union County CollegePlainfieldNew JerseyNJ 07016United States Department of Internal Medicine Lloydminster Regional HospitalLloydminster S9V 1Y5SaskatchewanCanada

There have been numerous concerns about the disease and how it affects the human body since the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)pandemic began in December *** impact of SARS-CoV-2 on the liver is being carefully investigated due to an increase in individuals with hepatitis and other liver illnesses,such as alcoholic liver ***,the liver is involved in the metabolism of numerous drugs used to treat comorbidities and coronavirus disease 2019(COVID-19).Determining how SARS-CoV-2 affects the liver and what factors place individuals with COVID-19 at a higher risk of developing liver problems are the two main objectives of this *** evaluation of the literature included research from three major scientific *** provide an update on the current impact of COVID-19 on the liver,data was collected and relevant information was incorporated into the *** more knowledge about the effect of the disease on the liver,better management and therapeutics can be developed,and education can ultimately save lives and reduce the long-term impact of the pandemic on our population.

关键词： Coronavirus COVID-19 SARS-CoV-2 Liver Hepatic complications

Comorbidity of Attention-Deficit/Hyperactivity Disorder (ADHD) in Children with Epilepsy, Egyptian Study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neuroscience & Medicine 2020年第4期11卷 119-129页

作者： Nahed Salah El-din Ahmed Maha Ali Nada Randa Mohamed Amin omar Sayed Khalifa Ali Mohamed hamdy Ibrahim Neurology Department Faculty of Medicine Ain Shams University Cairo Egypt Neurology Department Faculty of Medicine Minia University Cairo Egypt

Background: Epilepsy is one of the most common neurological conditions with about 65 million people affected worldwide. It is also a common condition in children, where its prevalence is approximately 3.2 - 5.5/1000 in the developed world. Children with epilepsy (CWE) experience not only seizures but also multiple cognitive, behavioral, and emotional problems. ADHD is one of the more common comorbidities of childhood epilepsy. Objectives: To discuss the relationship between childhood epilepsy and comorbidities especially ADHD. Study Design: This is a prospective observational analytical cross-sectional study carried out on one hundred and fifteen patients at Ain Shams University and Nasr-city Health Insurance out-patient clinics, Cairo, Egypt fulfilling the inclusion criteria. Patients were selected by simple random sample. Results: ADHD is very common epilepsy comorbidity in Egyptian epileptic children with under-diagnosis and treatment. Conclusion: Frequent assessment for ADHD in epileptic children is mandatory for better quality of life.

关键词： Attention Deficit Seizures Comorbidity Egyptian Study

Relation between Carotid Artery Plaques Characteristics as a Predictor of Haemodynamics Changes after Carotid Artery Stenting

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neuroscience & Medicine 2021年第1期12卷 12-21页

作者： Hany Mahmoud Zaki ei-Dine Mohamed Khaled Elewa Tamer Mahmoud Elsayed Roushdy omar Mohamed Hashim Mohamed hamdy Ibrahim Neurology Department Faculty of Medicine Ain Shams University Cairo Egypt Railway Hospital Ministry of Health Cairo Egypt

Objectives: To study relationship between carotid artery plaques characteristics and haemodynamic changes after carotid stenting. Patients and Methods: This observational prospective (pilot) study included 20 patients—who underwent CAS. The study was carried out in Ain shams university hospitals—Railway hospital (ERMED) and Suez insurance hospital from December 2018 to February 2020. Inclusion criteria, Symptomatic (defined as amaurosis fugax, TIA, Minor stroke or Major stroke) stenosis > 70%. Asymptomatic stenosis > 80% (accidentally discovered during pre-operative assessment for CABG and during full assessment for irrelevant stroke). Results: Regarding to plaque character for degree of stenosis, calcification and ulceration revealed significantly higher degree of stenosis in hemodynamic events group (P = 0.024). On the other hand, that there was no statistically significant difference between the two groups as regard calcification, ulceration and lesion location. Conclusion: The study revealed that HI is a common occurrence following CAS procedures and significantly higher degree of stenosis in hemodynamic events group. Plaque shape, ulcerations hardly affect haeodynamic instability after carotid stenting.

关键词： Carotid Artery Plaques Carotid Stenting Haemodynamics Carotid Stenosis

Trends and outcomes of pancreaticoduodenectomy for periampullary tumors: A 25-year single-center study of 1000 consecutive cases

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2017年第38期23卷 7025-7036页

作者： ayman el nakeeb waleed askar ehab atef ehab el hanafy ahmad m sultan tarek salah ahmed shehta mohamed el sorogy emad hamdy mohamed el hemly ahmed a el-geidi tharwat kandil mohamed el shobari talaat abd allah amgad fouad mostafa abu zeid ahmed abu el eneen nabil gad el-hak gamal el ebidy omar fathy ahmed sultan mohamed abdel wahab gastroenterology surgical center mansoura university

AIM To evaluate the evolution, trends in surgical approaches a n d r e c o n s t r u c t i o n t e c h n i q u e s, a n d i m p o r t a n t lessons learned from performing 1000 consecutive pancreaticoduodenectomies(PDs) for periampullary *** This is a retrospective review of the data of all patients who underwent PD for periampullary tumor during the period from January 1993 to April 2017. The data were categorized into three periods, including early period(1993-2002), middle period(2003-2012), and late period(2013-2017).RESULTS The frequency showed PD was increasingly performed after the year 2000. With time, elderly, cirrhotic and obese patients, as well as patients with uncinate process carcinoma and borderline tumor were increasingly selected for PD. The median operative time and postoperative hospital stay decreased significantly over the periods. Hospital mortality declined significantly, from 6.6% to 3.1%. Postoperative complications significantly decreased, from 40% to 27.9%. There was significant decrease in postoperative pancreatic fistula in the second 10 years, from 15% to 12.7%. There was a significant improvement in median survival and overall survival among the *** Surgical results of PD significantly improved, with mortality rate nearly reaching 3%. Pancreatic reconstruction following PD is still debatable. The survival rate was also improved but the rate of recurrence is still high, at 36.9%.

关键词： Pancreaticoduodenectomy Pancreaticogastrostomy Pancreaticojejunostomy 手术后的胰腺的管 Periampullary 肿瘤