检索结果-南通市图书馆

Intraductal Prostatic Carcinoma: Epidemiological and Anatomopathological Aspects in Dakar

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Pathology 2024年第2期14卷 54-63页

作者： Ibou Thiam Fabrice Senghor omar sow Kor Ndiaye Mohamed Moustapha Chérif Dial Anatomical Pathology Department Aristide Le Dantec University Hospital Dakar Senegal Anatomical Pathology Department Peace Hospital Ziguinchor Senegal General Surgery Department Peace Hospital Ziguinchor Senegal Anatomical Pathology Department Idrissa Pouye University Hospital Dakar Senegal

Introduction: Intraductal carcinoma is often associated with high-grade, high-stage adenocarcinoma. Its frequency is variable and it is considered a poor prognostic factor. In our context, when prostatic carcinoma is diagnosed, pathologists do not always report the presence of this anatomopathological entity. We therefore conducted a study to determine the epidemiological and anatomopathological profile of patients with this lesion in Dakar. Materials and Methods: This is a retrospective descriptive study covering a 1-year period from January to December 2022. It focused on cases of intraductal carcinoma diagnosed among prostatic carcinomas collected in the anatomopathology laboratories of Hôpital Général Idrissa Pouye (HOGIP) and Hôpital Militaire de Ouakam (HMO). It was based on archives of anatomopathological reports, blocks and slides. A total of 200 cases of prostatic carcinoma were collated and reviewed to identify those presenting with intraductal carcinoma according to the diagnostic criteria of Guo and Epstein. Results: 87 cases of intraductal carcinoma were found, representing 43.5% of prostatic carcinomas. The mean age was 71 years. Patients in their seventh decade were the most represented, i.e. 42.5%. The majority of samples examined were biopsies (72.4%). The mean PSA level was 965.91 ng/ml, with extremes ranging from 0.03 to 10,000 ng/ml. Histologically, 96.5% of cases (N = 84) were invasive prostatic carcinoma. Gleason score 8 (4 + 4) was the most common, accounting for 42.53% (N = 37). On average, the study found four (04) foci of intraductal carcinoma per specimen, with extremes ranging from 1 to 30. Dense cribriform architecture accounted for 78.16%, loose cribriform for 11.5%, solid for 8.04% and micropapillary for 2.3%. Six cases (6.9%) showed foci of comedonecrosis. The vast majority of radical prostatectomies (87.5%) were classified as pT3. Node invasion and perineural sheathing were observed in 12.5% and 52.32% of cases respectively. Conclusi

关键词： Intraductal Carcinoma Prostate Pathological Anatomy Senegal

Results of the Management of Gastrointestinal Stromal Tumors (GIST): About 6 Cases at the Vichy Hospital Center (France)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Cancer Therapy 2022年第7期13卷 397-404页

作者： omar sow Nicolas Sorbane Fetche Vermare Clarisse Annabel Bautrand Alice Anusca Lionel Perrot Department of Visceral and Digestive Surgery Vichy Hospital Center Vichy France Department of Surgery H&ocirc pital de la Paix Assane Seck University Ziguinchor Senegal

The aim of our study was to analyze the results of surgical management of gastrointestinal stromal tumors (GIST) at the Vichy Hospital Center. Methodology: Between 2010 and 2020, the data of 6 patients operated at the Vichy Hospital Center for GIST were analyzed. The parameters studied were: age, sex, antecedents, discovery circumstances, imagery, surgical procedure, anatomopathological data, the follow-up and the morbidity-mortality. Results: There were 5 men and one woman with an average age of 72.16 years [58 - 80 years]. The average time of evolution was 8 months (0 - 14 months). The diagnosis was fortuitous in 2 cases. Atypical abdominal pain was the main symptom in 3 cases. One case was received in a clinical picture of peritoneal irritation syndrome. Echo-endoscopy with biopsy specimen histology made it possible to make the diagnosis in 5 cases and the surgical specimen in 1 case. The fusiform type was the predominant histological form. The stomach was the most common location. The average size of GISTs was 7.3 × 4 cm with a positive C Kit in all patients. Neoadjuvant chemotherapy was performed on one patient. Surgery was curative and was done laparoscopically on 4 patients. Adjuvant chemotherapy based on Imatinib at a rate of 400 mg/d in 3 patients was initiated. One patient presented a fistula of the esophagus-jejunal anastomosis on D6 post operation controlled by a drainage and an antibiotic therapy. Mortality was zero. During the surgery, all of the patients were followed up with surgeon, oncologist. Conclusion: GISTs are the most common mesenchymal tumors of the digestive tract with a preferential gastric location. Laparoscopic surgery, with advances in molecular biology and the introduction of targeted therapy has improved the management of these tumors in terms of morbidity and mortality.

关键词： Gastrointestinal Stromal Tumor Laparoscopic Surgery Targeted Therapy

Management of Acute Bowel Obstruction in Adults in Ziguinchor Hospital Establishments: About 163 Cases Followed Up

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Surgical Science 2024年第4期15卷 207-218页

作者： omar sow Cheikh H. Badji Mouhamed Dieng Reymond Seydi Aissata Diallo Cheikh Diouf Papa A. Ba Boubacar Fall Department of General Surgery Peace Hospital Assane Seck University of Ziguinchor Ziguinchor Senegal Department of General Surgery Central Regional Hospital of Ziguinchor Assane Seck University of Ziguinchor Ziguinchor Senegal Department of General Surgery University of Iba Der Thiam Thies Senegal

Acute intestinal obstruction represents a very frequent admission to surgical emergencies. The aim of our study was to make a descriptive analysis of the management of acute intestinal obstructions at the level of hospital establishments in Ziguinchor. Materials and Methods: This was a retrospective, descriptive, multicenter study from the period of January 1, 2017 to December 31, 2021. Patients over 15 years of age admitted for occlusive syndrome in the two surgical departments of the Ziguinchor regional hospitals were included in the study. Epidemiological, diagnostic, therapeutic and evolutionary data were studied. Results: Acute intestinal occlusions accounted for 8.3% of admissions. A total of 163 patients were enrolled, 61.9% were men, sex ratio of 1.6. The mean age was 48.7 years. The average consultation time was 74.8 hours (3.12 days). The total occlusive syndrome was in 48.5% of the cases. Abdominal pain was present in 87.1%, vomiting in 74.2%, cessation of matter and gas in 60.7% and meteorism in 36.2%. Biological lab tests reported hyperleukocytosis in 28.1% of the cases. Abdominal CT scans were performed in 71.2%, confirming the diagnosis in 90.5% and determining the etiology in 93.1%. The zone of the obstruction in the small bowel was 62.7%, and in the colon in 37.3%. Functional occlusions accounted for 22.7% of cases and mechanical for 77.3%, including 120 cases of strangulation occlusion (95.2%) and 6 cases of obstruction. Etiologies were dominated by adhesions and/or fibrous bands (61.2%). Medical treatment resolved the occlusive syndrome in 9.2% of cases, instrumental treatment in 17.1% and surgical treatment in 77.3%. Adhesiolysis/section of fibrous bands (55.7%), detorsion (14.3%) and resection anastomosis (11.9%) were the most common surgical procedures. Overall morbidity was 11.6%, dominated by surgical site infection (7.14%). The mean resumption of intestinal transit was 2.7 days, and the mean hospital stay was 7.9 days. Overall mortality was

关键词： Intestinal Obstruction Emergency Surgery Ziguinchor

The First Cases of Laparoscopic Colectomy for Cancer in Ziguinchor Peace Hospital

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Surgical Science 2023年第8期14卷 550-556页

作者： omar sow Aissé Thioubou Reymond Saidy Aboubacar Traoré Modou D. Ndiaye Mouhamadou L. Gueye Ibrahima Ka Madieng Dieng Department of Surgery Peace Hospital Assane Seck University Ziguinchor Senegal Department of General Surgery Cheikh Anta Diop University Dakar Senegal

Laparoscopic colectomy is a standardized technique for the curative treatment of colon cancer, based on the principles of carcinological surgery. It is rarely performed in our region but common practice in developed countries. We conducted a retrospective study of the first 4 cases of laparoscopic colectomy for cancer. The patients were 3 men and 1 woman, with a mean age of 54.2 years. Of the 4 cancers, 3 were localized to the sigmoid and one to the cecum. The main symptom was rectal bleeding. Total colonoscopy with biopsy was performed in 3 patients and the histological type was a lieberkühnian, infiltrative, moderately differentiated adenocarcinoma. Thoraco-abdomino-pelvic computed tomography (TAP CT) was performed in all the cases. Three patients were presented to the multidisciplinary team (MDT) prior to surgery. The operations were one right hemicolectomy and three left hemicolectomies. The mean operative time was 182.25 min [152 - 210]. Average blood loss was estimated at 200 cc. The average hospital stay was 4.71 days. Cancer staging was classified as stage I in 1 case (p T1N0M0) and stage III in 3 cases (pT3N1Mx, pT3N2Mx). Resection margins were healthy. The number of lymph nodes removed was 12, 14, 17 and 13 respectively. Conclusion: This is a safe and reproducible technique, but requires a much higher cost than laparotomy.

关键词： Colectomy Cancer Laparoscopy Ziguinchor

Intraductal Prostatic Carcinoma: Epidemiological and Anatomopathological Aspects in Dakar

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Management of Acute Bowel Obstruction in Adults in Ziguinchor Hospital Establishments:About 163 Cases Followed Up

Open Journal of Pathology（病理学期刊） 2024年第2期 54页

作者： Ibou Thiam Fabrice Senghor omar sow Kor Ndiaye Mohamed Moustapha Chérif Dial

来源：博看期刊评论

在线全文

博看期刊

学校读者我要写书评

暂无评论

The First Cases of Laparoscopic Colectomy for Cancer in Ziguinchor Peace Hospital

Surgical Science（外科学） 2024年第4期 207页

作者： omar sow Cheikh H.Badji Mouhamed Dieng Reymond Seydi Aissata Diallo Cheikh Diouf Papa A.Ba Boubacar Fall

来源：博看期刊评论

在线全文

博看期刊

学校读者我要写书评

暂无评论

Application of solvent evaporation technique for pure drug crystal spheres preparation

Surgical Science（外科学） 2023年第8期

作者： omar sow Aissé Thioubou Reymond Saidy Aboubacar Traoré Modou D. Ndiaye Mouhamadou L. Gueye Ibrahima Ka Madieng Dieng

来源：博看期刊评论

在线全文

博看期刊

学校读者我要写书评

暂无评论

Particuology 2022年第8期20卷 79-89页

作者： omar Mady Department of Pharmaceutical Technology Faculty of Pharmacy Tanta UniversityEgypt

An innovative application ofthe solventevaporation technique was *** tech nique is a technique for drug encapsulation and nanosphere *** widely used technique is also facing the problem of low actual drug entrapment percent,which is not economic from the industrial *** goal of this work is trying to use the advantage of this technique concerning the product sphericity and the ability to control particle size,to prepare a drug as pure crystals *** is selected as a model *** spheres are formed by using Polyvinyl pyrrolidone(PVP)or Polyethylene glycol(PEG)as an anti-aggregating agent but not formed on using tween or *** size and actual drug content depend on the concentrations the anti-aggregating agent *** of the drug crystal spheres are porous with empty sphere internal structure on using PvP but spongy and rough on using *** drug has its identity chemical form in the drug crystal *** scan of spheres prepared on using PEG showed a characteristic ether *** showed melting endothermic peak of PEG,but X-ray showed minor change in the drug crystal *** release profiles from crystal spheres prepared with the same anti-aggregating agent are close to each *** drug release profiles from drug crystal spheres prepared by using PEG are more controlled than that prepared by using *** drug release mechanism is *** was concluded that,the same technique could be suggested for preparation ofother biomedical material in pure crystals spheres with controlled particle *** properties may encourage to prepare very small particles with spherical shape for inhalation or injection as an innovative particle technology application for the widely used technique.

关键词： Solvent evaporation technique Drug crystal spheres Ibuprofen Polyvinyl pyrrolidone Polyethylene glycol

Monolayer MoS_(2)/n-Si Heterostructure Schottky Solar Cell

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Renewable Materials 2022年第7期10卷 1979-1988页

作者： omar Salih omar The University of Duhok College of ScienceDepartment of PhysicsDuhokKurdistan RegionIraq

Monolayer MoS_(2)has a promising optoelectronics property,with a bandgap in the visible range;the material is a potential candidate for solar cell *** this work,we grew MoS_(2)monolayers using a low-pressure chemical vapor deposition *** produce uniform wafer-scale MoS_(2)monolayer films,precursors molybdenum dioxide(MoO_(2))and sulfur(S)are *** force microscopy was used to quantify the thickness of the monolayers,and the result was validated by Raman *** electron microscopy(TEM)was used to confirm the crystalline quality of the monolayers,and photoluminescence spectroscopy was used to evaluate their optical *** were able to create a Schottky solar cell with a MoS_(2)monolayer up to 1 cm2 area by transferring monolayer film to n-type *** MoS_(2)/n-Si Schottky solar cell demonstrated photovoltaic characteristics with a short circuit current density of 14.8 mA cm^(-2)and an open-circuit voltage of 0.32 V under 100 mW cm^(-2)*** fill factor and energy conversion efficiency were 53%and 2.46%,respectively,with the highest external quantum efficiency at 530 nm being 44%.

关键词： MoS_(2)monolayers chemical vapor deposition Schottky solar cell